Standard knownness: 2.3; Custom knownness: None; Num. species: 32; Orthology database: Panther19.0; Protein members: 38
Molecular function: vesicle cytoskeletal trafficking2019, 2020, 2024 negative regulation of proteasomal protein catabolic process2019, 2024 protein stabilization2022
Cellular component: early endosome2019, 2020, 2024 nucleus2010, 2019, 2024 nuclear body2019, 2024 cytoplasm2019, 2024 endosome2024 membrane2024
| Chordates: | 19/21 | ![]()  | 
                   
                 
| Echinoderms: | 0/0 | |
| Hemichordates: | 1/1 | |
| Annelids: | 1/1 | |
| Molluscs: | 0/0 | |
| Bryozoans: | 0/0 | |
| Platyhelminthes: | 0/0 | |
| Rotifers: | 0/0 | |
| Nematodes: | 0/3 | |
| Arthropods: | 5/5 | |
| Tardigrades: | 0/0 | |
| Placozoa: | 1/1 | |
| Cnidaria: | 1/1 | |
| Porifera: | 0/0 | |
| Choanoflagellates+: | 1/1 | |
| Dikarya: | 0/14 | |
| Fungi (other): | 0/1 | |
| Protozoa: | 2/3 | |
| Excavates: | 1/4 | |
| Harosa: | 0/4 | |
| Hacrobia: | 0/0 | |
| Plants: | 0/39 | |
| Archea: | 0/8 | |
| Bacteria: | 0/35 | 
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| UniProt ID Organism DB»  | 
	    
        
          
            Standard knownness | clustom knownness | Gene name | Description | Species [Key only] | GO terms | Seq. links | Protein domain links | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 
        HAP40_RAT RGD»  | 
        
          
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        F8a1 | 40-kDa huntingtin-associated protein (Factor VIII intron 22 protein)  | 
        
        Rattus norvegicus TI:10116 None  | 
        
          
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        HAP40_HUMAN Ensembl»  | 
        
          
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        F8A1; F8A2; F8A3 | 40-kDa huntingtin-associated protein (HAP40) (CpG island protein) (Factor VIII intron 22 protein)  | 
        
        Homo sapiens TI:9606 None  | 
        
          
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        HAP40_MOUSE Ensembl»  | 
        
          
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        F8a1 | 40-kDa huntingtin-associated protein (CpG island protein) (Factor VIII intron 22 protein)  | 
        
        Mus musculus TI:10090 None  | 
        
          
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| 
        H2R4G8_PANTR Ensembl»  | 
        
          
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        F8A1 | Coagulation factor VIII associated 3 (Coagulation factor VIII-associated 1)  | 
        
        Pan troglodytes TI:9598 None  | 
        
          
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| 
        A0A139WE85_TRICA EnsemblMetazoa»  | 
        
          
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        AUGUSTUS-3.0.2_34009 | Factor VIII intron 22 protein-like Protein | 
        Tribolium castaneum TI:7070 None  | 
        
          
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| 
        A9VAL0_MONBE EnsemblProtists»  | 
        
          
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        MONBRDRAFT_34266 | R3H domain-containing protein | 
        Monosiga brevicollis TI:81824 None  | 
        
          
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| 
        Q9VXR6_DROME FlyBase»  | 
        
          
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        Hap40 | GH09650p (Uncharacterized protein, isoform A) (Uncharacterized protein, isoform B)  | 
        
        Drosophila melanogaster TI:7227 None  | 
        
          
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| 
        A0A1S4HDZ6_ANOGA EnsemblMetazoa»  | 
        
          
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        Factor VIII intron 22 protein | 
        Anopheles gambiae TI:7165 None  | 
        
          
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| 
        A0A2I3SRC6_PANTR Ensembl»  | 
        
          
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        Factor VIII intron 22 protein | 
        Pan troglodytes TI:9598 None  | 
        
          
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| 
        A0A337STW8_FELCA Ensembl»  | 
        
          
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        LOC101095239 | Factor VIII intron 22 protein | 
        Felis catus TI:9685 None  | 
        
          
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        A0A3B3I775_ORYLA Ensembl»  | 
        
          
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        LOC101157109 | Factor VIII intron 22 protein | 
        Oryzias latipes TI:8090 None  | 
        
          
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| 
        A0A3Q2H601_HORSE Ensembl»  | 
        
          
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        F8A1 | Factor VIII intron 22 protein | 
        Equus caballus TI:9796 None  | 
        
          
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| 
        A0A5F5XBQ2_FELCA Ensembl»  | 
        
          
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        Factor VIII intron 22 protein | 
        Felis catus TI:9685 None  | 
        
          
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| 
        A0A5F7ZD20_MACMU Ensembl»  | 
        
          
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        Factor VIII intron 22 protein | 
        Macaca mulatta TI:9544 None  | 
        
          
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| 
        A0A7M7SYH3_STRPU EnsemblMetazoa»  | 
        
          
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        Factor VIII intron 22 protein | 
        Strongylocentrotus purpuratus TI:7668 None  | 
        
          
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| 
        A0JMS8_XENLA Xenbase»  | 
        
          
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        f8a1.L | Coagulation factor VIII L homeolog (F8a1 protein)  | 
        
        Xenopus laevis TI:8355 None  | 
        
          
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| 
        A2BIC9_DANRE ZFIN»  | 
        
          
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        si:ch211-243a20.2 | Factor VIII intron 22 protein isoform X1 (Zgc:101679)  | 
        
        Danio rerio TI:7955 None  | 
        
          
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| 
        A2DHA7_TRIV3 VEuPathDB»  | 
        
          
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        TVAG_021250 | Uncharacterized protein | 
        Trichomonas vaginalis TI:5722 None  | 
        
          
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| 
        A2DHE5_TRIV3 VEuPathDB»  | 
        
          
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        TVAG_021650 | Uncharacterized protein | 
        Trichomonas vaginalis TI:5722 None  | 
        
          
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| 
        A2G453_TRIV3 VEuPathDB»  | 
        
          
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        TVAG_143830 | Transcriptional regulator | 
        Trichomonas vaginalis TI:5722 None  | 
        
          
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| 
        A2G6T3_TRIV3 VEuPathDB»  | 
        
          
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        TVAG_255370 | Uncharacterized protein | 
        Trichomonas vaginalis TI:5722 None  | 
        
          
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| 
        A7RY05_NEMVE EnsemblMetazoa»  | 
        
          
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        NEMVEDRAFT_v1g228977 | Factor VIII intron 22 protein | 
        Nematostella vectensis TI:45351 None  | 
        
          
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| 
        B3RN17_TRIAD EnsemblMetazoa»  | 
        
          
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        TRIADDRAFT_53007 | Factor VIII intron 22 protein | 
        Trichoplax adhaerens TI:10228 None  | 
        
          
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| 
        B7PGC8_IXOSC EnsemblMetazoa»  | 
        
          
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        8052493 | Factor VIII intron 22 protein | 
        Ixodes scapularis TI:6945 None  | 
        
          
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| 
        E9H2U2_DAPPU EnsemblMetazoa»  | 
        
          
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        DAPPUDRAFT_307550 | EOG090X06TI | 
        Daphnia pulex TI:6669 None  | 
        
          
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| 
        F0ZUR8_DICPU EnsemblProtists»  | 
        
          
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        DICPUDRAFT_38570 | Uncharacterized protein | 
        Dictyostelium purpureum TI:5786 None  | 
        
          
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| 
        F1RZ35_PIG Ensembl»  | 
        
          
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        F8A1 | Factor VIII intron 22 protein | 
        Sus scrofa TI:9823 None  | 
        
          
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        |||||
| 
        F6ZSW9_MONDO Ensembl»  | 
        
          
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        Factor VIII intron 22 protein | 
        Monodelphis domestica TI:13616 None  | 
        
          
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        |||||||
| 
        F7A2P7_MACMU Ensembl»  | 
        
          
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        Factor VIII intron 22 protein | 
        Macaca mulatta TI:9544 None  | 
        
          
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| 
        G3QM27_GORGO Ensembl»  | 
        
          
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        Factor VIII intron 22 protein | 
        Gorilla gorilla TI:9593 None  | 
        
          
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        ||||||
| 
        G3X7W1_BOVIN Ensembl»  | 
        
          
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        F8A1 | Factor VIII intron 22 protein | 
        Bos taurus TI:9913 None  | 
        
          
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| 
        H9GMK2_ANOCA Ensembl»  | 
        
          
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        LOC100551683 | Factor VIII intron 22 protein | 
        Anolis carolinensis TI:28377 None  | 
        
          
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| 
        Q55FH3_DICDI dictyBase»  | 
        
          
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        DDB_G0268116 | Uncharacterized protein | 
        Dictyostelium discoideum TI:44689 None  | 
        
          
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        |||||
| 
        T1G876_HELRO EnsemblMetazoa»  | 
        
          
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        20217273 | Factor VIII intron 22 protein | 
        Helobdella robusta TI:6412 None  | 
        
          
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        |||||
| 
        A0A8I3Q617_CANLF Ensembl»  | 
        
          
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        Uncharacterized protein | 
        Canis lupus TI:9612 None  | 
        
          
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| 
        A0A8V0Z3P7_CHICK Ensembl»  | 
        
          
  | 
        
          
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        F8A3 | Factor VIII intron 22 protein | 
        Gallus gallus TI:9031 None  | 
        
          
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        |||||||
| 
        A0A9J7M770_BRAFL CTD»  | 
        
          
  | 
        
          
  | 
        LOC118429504 | 40-kDa huntingtin-associated protein-like | 
        Branchiostoma floridae TI:7739 None  | 
        
          
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        |||||||
| 
        Q0P4L3_XENTR Xenbase»  | 
        
          
  | 
        
          
  | 
        f8a1 | Coagulation factor VIII (F8A1 protein) | 
        Xenopus tropicalis TI:8364 None  | 
        
          
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        ||||||