Standard knownness: 6.5; Custom knownness: None; Num. species: 40; Orthology database: Panther19.0; Protein members: 60
Molecular function: U2 snRNA 3'-end processing2008, 2017, 2025 RNA polymerase II transcription initiation surveillance2025 snRNA processing2009, 2012, 2025 regulation of transcription elongation by RNA polymerase II2025 negative regulation of apoptotic process2008 inner cell mass cell proliferation2008 embryo implantation2023 blastocyst growth2008 snRNA 3'-end processing2012 positive regulation of neuron differentiation2019
Cellular component: integrator complex2012, 2024, 2025 nucleus2008, 2024, 2025 INTAC complex2025 nuclear membrane2025 recycling endosome2025 plasma membrane2025 nucleoplasm2015 membrane2014 cytoskeleton2025 cell projection2025
| Chordates: | 22/21 | ![]() |
| Echinoderms: | 0/0 | |
| Hemichordates: | 1/1 | |
| Annelids: | 1/1 | |
| Molluscs: | 0/0 | |
| Bryozoans: | 0/0 | |
| Platyhelminthes: | 0/0 | |
| Rotifers: | 0/0 | |
| Nematodes: | 3/3 | |
| Arthropods: | 5/5 | |
| Tardigrades: | 0/0 | |
| Placozoa: | 1/1 | |
| Cnidaria: | 1/1 | |
| Porifera: | 0/0 | |
| Choanoflagellates+: | 0/1 | |
| Dikarya: | 0/14 | |
| Fungi (other): | 0/1 | |
| Protozoa: | 2/3 | |
| Excavates: | 0/4 | |
| Harosa: | 2/4 | |
| Hacrobia: | 0/0 | |
| Plants: | 2/39 | |
| Archea: | 0/8 | |
| Bacteria: | 0/35 |
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| UniProt ID Organism DB» |
Standard knownness | clustom knownness | Gene name | Description | Species [Show all] | GO terms | Seq. links | Protein domain links | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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O01483_CAEEL WormBase» |
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ints-1 | Integrator complex subunit 1 RPB2-binding domain-containing protein |
Caenorhabditis elegans TI:6239 None |
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A0ACD6B7E6_DANRE ZFIN» |
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ints1 | Integrator complex subunit 1 |
Danio rerio TI:7955 None |
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INT1_DICDI dictyBase» |
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ints1 | Integrator complex subunit 1 homolog |
Dictyostelium discoideum TI:44689 None |
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INT1_DROME FlyBase» |
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IntS1 | Integrator complex subunit 1 |
Drosophila melanogaster TI:7227 None |
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A0A8V0Z496_CHICK Ensembl» |
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INTS1 | Integrator complex subunit 1 |
Gallus gallus TI:9031 None |
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INT1_HUMAN Ensembl» |
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INTS1 | Integrator complex subunit 1 (Int1) |
Homo sapiens TI:9606 None |
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INT1_MOUSE Ensembl» |
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Ints1 | Integrator complex subunit 1 (Int1) |
Mus musculus TI:10090 None |
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F1M8D7_RAT RGD» |
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Ints1 | Integrator complex subunit 1 |
Rattus norvegicus TI:10116 None |
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