Collated Gene Ontology terms

Biological process: metal ion binding(2025)

Molecular function: U2 snRNA 3'-end processing2008, 2017, 2025 RNA polymerase II transcription initiation surveillance2025 snRNA processing2009, 2012, 2025 regulation of transcription elongation by RNA polymerase II2025 negative regulation of apoptotic process2008 inner cell mass cell proliferation2008 embryo implantation2023 blastocyst growth2008 snRNA 3'-end processing2012 positive regulation of neuron differentiation2019

Cellular component: integrator complex2012, 2024, 2025 nucleus2008, 2024, 2025 INTAC complex2025 nuclear membrane2025 recycling endosome2025 plasma membrane2025 nucleoplasm2015 membrane2014 cytoskeleton2025 cell projection2025

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 2/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
A0A2R6X798_MARPO
euHCVdb»
0.0
MARPO_0032s0133 DUF3677 domain-containing protein Marchantia polymorpha
TI:3197 None
 
A0A7I4D9I5_PHYPA
EnsemblPlants»
0.0
LOC112274712 DUF3677 domain-containing protein Physcomitrium patens
TI:3218 None
 
F1A4U5_DICPU
TubercuList»
0.0
DICPUDRAFT_100030 DUF3677 domain-containing protein Dictyostelium purpureum
TI:5786 None
 
H3GGN5_PHYRM
EnsemblProtists»
0.0
Glutamate carboxypeptidase Phytophthora ramorum
TI:164328 None
 
A0A2A6BFI0_PRIPA
EnsemblMetazoa»
0.0
WBGene00118157 Inst-1 Pristionchus pacificus
TI:54126 None
   
A0A2R6W2Z2_MARPO
neXtProt»
0.0
MARPO_0170s0022 Integrator complex subunit
1 INTS2-binding domain-containing protein		 Marchantia polymorpha
TI:3197 None
 
A0A2R6XUY4_MARPO
neXtProt»
0.0
MARPO_0001s0008 Integrator complex subunit
1 INTS2-binding domain-containing protein		 Marchantia polymorpha
TI:3197 None
 
A7TCK4_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g225280 Integrator complex subunit
1 INTS2-binding domain-containing protein		 Nematostella vectensis
TI:45351 None
 
B8BQ18_THAPS
euHCVdb»
0.0
THAPSDRAFT_20681 Integrator complex subunit
1 RPB2-binding domain-containing protein		 Thalassiosira pseudonana
TI:35128 None
 
E9GHA6_DAPPU
neXtProt»
0.0
DAPPUDRAFT_242719 Integrator complex subunit
1 INTS2-binding domain-containing protein		 Daphnia pulex
TI:6669 None
 
E9HJE9_DAPPU
neXtProt»
0.0
DAPPUDRAFT_260637 Integrator complex subunit
1 INTS2-binding domain-containing protein		 Daphnia pulex
TI:6669 None
 
E9HPE2_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_332240 Integrator complex subunit
1 INTS2-binding domain-containing protein		 Daphnia pulex
TI:6669 None
 
H3H4N3_PHYRM
EnsemblProtists»
0.0
Integrator complex subunit
1 RPB2-binding domain-containing protein		 Phytophthora ramorum
TI:164328 None
 
O01483_CAEEL
WormBase»
0.5
ints-1 Integrator complex subunit
1 RPB2-binding domain-containing protein		 Caenorhabditis elegans
TI:6239 None
 
A0A1L8EXS4_XENLA
Xenbase»
0.0
ints1.L Integrator complex subunit 1 Xenopus laevis
TI:8355 None
   
A0A1S4GX41_ANOGA
EnsemblMetazoa»
0.0
Integrator complex subunit 1 Anopheles gambiae
TI:7165 None
 
A0A5F8A532_MACMU
Ensembl»
0.0
INTS1 Integrator complex subunit 1 Macaca mulatta
TI:9544 None
   
A0A7M7NCY9_STRPU
EnsemblMetazoa»
0.0
Integrator complex subunit 1 Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7NQM3_STRPU
EnsemblMetazoa»
0.0
Integrator complex subunit 1 Strongylocentrotus purpuratus
TI:7668 None
   
A0A8I3N7E9_CANLF
Ensembl»
0.0
INTS1 Integrator complex subunit 1 Canis lupus
TI:9612 None
   
A0A8V0Z496_CHICK
Ensembl»
0.5
INTS1 Integrator complex subunit 1 Gallus gallus
TI:9031 None
   
A0AAA9TV32_BOVIN
Ensembl»
0.0
INTS1 Integrator complex subunit 1 Bos taurus
TI:9913 None
   
A0ABI7W630_FELCA
Ensembl»
0.0
INTS1 Integrator complex subunit 1 Felis catus
TI:9685 None
   
A0ACD6B7E6_DANRE
ZFIN»
0.0
ints1 Integrator complex subunit 1 Danio rerio
TI:7955 None 		     
A7SCM2_NEMVE
neXtProt»
0.0
NEMVEDRAFT_v1g244326 Integrator complex subunit 1 Nematostella vectensis
TI:45351 None
 
A7SCM5_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g50030 Integrator complex subunit 1 Nematostella vectensis
TI:45351 None
 
F1M8D7_RAT
RGD»
4.5
Ints1 Integrator complex subunit 1 Rattus norvegicus
TI:10116 None
   
F6QP93_ORNAN
Ensembl»
0.0
INTS1 Integrator complex subunit 1 Ornithorhynchus anatinus
TI:9258 None
   
F7AK08_HORSE
Ensembl»
0.0
INTS1 Integrator complex subunit 1 Equus caballus
TI:9796 None
   
F7AYL9_XENTR
Xenbase»
0.0
ints1 Integrator complex subunit 1 Xenopus tropicalis
TI:8364 None
   
F7GD11_MONDO
Ensembl»
0.0
INTS1 Integrator complex subunit 1 Monodelphis domestica
TI:13616 None
   
G3RH34_GORGO
Ensembl»
0.0
INTS1 Integrator complex subunit 1 Gorilla gorilla
TI:9593 None
 
H2LIX6_ORYLA
Ensembl»
0.0
INTS1 Integrator complex subunit 1 Oryzias latipes
TI:8090 None
   
H9GHC0_ANOCA
Ensembl»
0.0
INTS1 Integrator complex subunit 1 Anolis carolinensis
TI:28377 None
   
I3LRU6_PIG
Ensembl»
0.0
INTS1 Integrator complex subunit 1 Sus scrofa
TI:9823 None
   
INT1_DROME
FlyBase»
3.4
IntS1 Integrator complex subunit 1 Drosophila melanogaster
TI:7227 None
 
K7ATZ5_PANTR
Ensembl»
0.0
INTS1 Integrator complex subunit 1 Pan troglodytes
TI:9598 None
 
W5LZC6_LEPOC
Ensembl»
0.0
Integrator complex subunit 1 Lepisosteus oculatus
TI:7918 None
 
INT1_HUMAN
Ensembl»
4.1
INTS1 Integrator complex subunit 1 (Int1) Homo sapiens
TI:9606 None
 
INT1_MOUSE
Ensembl»
6.5
Ints1 Integrator complex subunit 1 (Int1) Mus musculus
TI:10090 None
 
INT1_DICDI
dictyBase»
1.0
ints1 Integrator complex subunit 1 homolog Dictyostelium discoideum
TI:44689 None
 
A0A9J7M5D8_BRAFL
euHCVdb»
0.0
LOC118428625 Integrator complex subunit 1-like Branchiostoma floridae
TI:7739 None
   
D6WAZ1_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_01242 Integrator complex subunit 1-like Protein Tribolium castaneum
TI:7070 None
 
B7PNY5_IXOSC
EnsemblMetazoa»
0.0
8051185 Integrator complex subunit, putative Ixodes scapularis
TI:6945 None
 
A8Y1I6_CAEBR
WormBase»
0.0
ints-1 Protein CBG22096 Caenorhabditis briggsae
TI:6238 None
 
A0A2R6WZA1_MARPO
neXtProt»
0.0
MARPO_0046s0006 Uncharacterized protein Marchantia polymorpha
TI:3197 None
 
B3S8E3_TRIAD
CTD»
0.0
TRIADDRAFT_60509 Uncharacterized protein Trichoplax adhaerens
TI:10228 None
 
E9FST9_DAPPU
neXtProt»
0.0
DAPPUDRAFT_310202 Uncharacterized protein Daphnia pulex
TI:6669 None
 
E9GHA8_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_317902 Uncharacterized protein Daphnia pulex
TI:6669 None
 
E9GHA9_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_317903 Uncharacterized protein Daphnia pulex
TI:6669 None
 
E9GV12_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_306111 Uncharacterized protein Daphnia pulex
TI:6669 None
 
E9HAG2_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_111914 Uncharacterized protein Daphnia pulex
TI:6669 None
 
E9HJH3_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_260581 Uncharacterized protein Daphnia pulex
TI:6669 None
 
E9HJK6_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_330438 Uncharacterized protein Daphnia pulex
TI:6669 None
 
E9HW27_DAPPU
neXtProt»
0.0
DAPPUDRAFT_334644 Uncharacterized protein Daphnia pulex
TI:6669 None
 
E9HW29_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_334645 Uncharacterized protein Daphnia pulex
TI:6669 None
 
E9HZN9_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_119856 Uncharacterized protein Daphnia pulex
TI:6669 None
 
H2XNV6_CIOIN
Ensembl»
0.0
Uncharacterized protein Ciona intestinalis
TI:7719 None
   
H3H7V3_PHYRM
EnsemblProtists»
0.0
Uncharacterized protein Phytophthora ramorum
TI:164328 None
 
T1FIQ3_HELRO
EnsemblMetazoa»
0.0
20208702 Uncharacterized protein Helobdella robusta
TI:6412 None