Standard knownness: 4.0; Custom knownness: None; Num. species: 39; Orthology database: Panther19.0; Protein members: 58
Molecular function: U2 snRNA 3'-end processing2008, 2017, 2024 snRNA processing2009, 2012, 2022, 2024 negative regulation of apoptotic process2008, 2024 inner cell mass cell proliferation2008, 2024 embryo implantation2023, 2024 blastocyst growth2008, 2024 snRNA 3'-end processing2012 regulation of transcription elongation by RNA polymerase II2022 positive regulation of neuron differentiation2019
Cellular component: integrator complex2009, 2012, 2017, 2022, 2024 nucleus2008, 2022, 2024 membrane2014, 2024 nuclear membrane2024 nucleoplasm2015
| Chordates: | 21/21 |  | 
| Echinoderms: | 0/0 | |
| Hemichordates: | 1/1 | |
| Annelids: | 1/1 | |
| Molluscs: | 0/0 | |
| Bryozoans: | 0/0 | |
| Platyhelminthes: | 0/0 | |
| Rotifers: | 0/0 | |
| Nematodes: | 3/3 | |
| Arthropods: | 5/5 | |
| Tardigrades: | 0/0 | |
| Placozoa: | 1/1 | |
| Cnidaria: | 1/1 | |
| Porifera: | 0/0 | |
| Choanoflagellates+: | 0/1 | |
| Dikarya: | 0/14 | |
| Fungi (other): | 0/1 | |
| Protozoa: | 2/3 | |
| Excavates: | 0/4 | |
| Harosa: | 2/4 | |
| Hacrobia: | 0/0 | |
| Plants: | 2/39 | |
| Archea: | 0/8 | |
| Bacteria: | 0/35 | 
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| UniProt ID Organism DB» | Standard knownness | clustom knownness | Gene name | Description | Species [Key only] | GO terms | Seq. links | Protein domain links | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A0A2R6X798_MARPO EnsemblPlants» | 
 | 
 | MARPO_0032s0133 | DUF3677 domain-containing protein | Marchantia polymorpha TI:3197 None |  |  |  | |||||
| A0A7I4D9I5_PHYPA EnsemblPlants» | 
 | 
 | DUF3677 domain-containing protein | Physcomitrium patens TI:3218 None |  |  |  | ||||||
| A0A7M7NCY9_STRPU EnsemblMetazoa» | 
 | 
 | DUF3677 domain-containing protein | Strongylocentrotus purpuratus TI:7668 None |  |  | |||||||
| A0A7M7NQM3_STRPU EnsemblMetazoa» | 
 | 
 | DUF3677 domain-containing protein | Strongylocentrotus purpuratus TI:7668 None |  |  | |||||||
| A7SCM5_NEMVE EnsemblMetazoa» | 
 | 
 | NEMVEDRAFT_v1g50030 | DUF3677 domain-containing protein | Nematostella vectensis TI:45351 None |  |  |  | |||||
| B3S8E3_TRIAD EnsemblMetazoa» | 
 | 
 | TRIADDRAFT_60509 | DUF3677 domain-containing protein | Trichoplax adhaerens TI:10228 None |  |  |  | |||||
| B8BQ18_THAPS EnsemblProtists» | 
 | 
 | THAPSDRAFT_20681 | DUF3677 domain-containing protein | Thalassiosira pseudonana TI:35128 None |  |  |  | |||||
| E9FST9_DAPPU EnsemblMetazoa» | 
 | 
 | DAPPUDRAFT_310202 | DUF3677 domain-containing protein | Daphnia pulex TI:6669 None |  |  |  | |||||
| F1A4U5_DICPU EnsemblProtists» | 
 | 
 | DICPUDRAFT_100030 | DUF3677 domain-containing protein | Dictyostelium purpureum TI:5786 None |  |  |  | |||||
| H2XNV6_CIOIN Ensembl» | 
 | 
 | DUF3677 domain-containing protein | Ciona intestinalis TI:7719 None |  |  | |||||||
| H3H4N3_PHYRM EnsemblProtists» | 
 | 
 | DUF3677 domain-containing protein | Phytophthora ramorum TI:164328 None |  |  |  | ||||||
| O01483_CAEEL WormBase» | 
 | 
 | ints-1 | DUF3677 domain-containing protein | Caenorhabditis elegans TI:6239 None |  |  |  | |||||
| T1FIQ3_HELRO EnsemblMetazoa» | 
 | 
 | 20208702 | DUF3677 domain-containing protein | Helobdella robusta TI:6412 None |  |  |  | |||||
| H3GGN5_PHYRM EnsemblProtists» | 
 | 
 | Glutamate carboxypeptidase | Phytophthora ramorum TI:164328 None |  |  |  | ||||||
| A0A2A6BFI0_PRIPA EnsemblMetazoa» | 
 | 
 | WBGene00118157 | Inst-1 | Pristionchus pacificus TI:54126 None |  |  |  | |||||
| E9HPE2_DAPPU EnsemblMetazoa» | 
 | 
 | DAPPUDRAFT_332240 | Integrator complex subunit 5 C-terminal domain-containing protein | Daphnia pulex TI:6669 None |  |  |  | |||||
| A0A0R4IJ75_DANRE ZFIN» | 
 | 
 | ints1 | Integrator complex subunit 1 | Danio rerio TI:7955 None |  |  |  | |||||
| A0A1L8EXS4_XENLA Xenbase» | 
 | 
 | ints1.L | Integrator complex subunit 1 | Xenopus laevis TI:8355 None |  |  | ||||||
| A0A1S4GX41_ANOGA EnsemblMetazoa» | 
 | 
 | Integrator complex subunit 1 | Anopheles gambiae TI:7165 None |  |  |  | ||||||
| A0A5F8A532_MACMU Ensembl» | 
 | 
 | INTS1 | Integrator complex subunit 1 | Macaca mulatta TI:9544 None |  |  | ||||||
| A0A8I3N7E9_CANLF Ensembl» | 
 | 
 | INTS1 | Integrator complex subunit 1 | Canis lupus TI:9612 None |  |  | ||||||
| A0A8V0Z496_CHICK Ensembl» | 
 | 
 | INTS1 | Integrator complex subunit 1 | Gallus gallus TI:9031 None |  |  | ||||||
| A7SCM2_NEMVE EnsemblMetazoa» | 
 | 
 | NEMVEDRAFT_v1g244326 | Integrator complex subunit 1 | Nematostella vectensis TI:45351 None |  |  |  | |||||
| F6QP93_ORNAN Ensembl» | 
 | 
 | INTS1 | Integrator complex subunit 1 | Ornithorhynchus anatinus TI:9258 None |  |  | ||||||
| F7AK08_HORSE Ensembl» | 
 | 
 | INTS1 | Integrator complex subunit 1 | Equus caballus TI:9796 None |  |  | ||||||
| F7AYL9_XENTR Xenbase» | 
 | 
 | gcnt4 | Integrator complex subunit 1 | Xenopus tropicalis TI:8364 None |  |  | ||||||
| F7GD11_MONDO Ensembl» | 
 | 
 | INTS1 | Integrator complex subunit 1 | Monodelphis domestica TI:13616 None |  |  | ||||||
| G3RH34_GORGO Ensembl» | 
 | 
 | INTS1 | Integrator complex subunit 1 | Gorilla gorilla TI:9593 None |  |  |  | |||||
| H2LIX6_ORYLA Ensembl» | 
 | 
 | ints1 | Integrator complex subunit 1 | Oryzias latipes TI:8090 None |  |  | ||||||
| H9GHC0_ANOCA Ensembl» | 
 | 
 | INTS1 | Integrator complex subunit 1 | Anolis carolinensis TI:28377 None |  |  | ||||||
| I3LRU6_PIG Ensembl» | 
 | 
 | INTS1 | Integrator complex subunit 1 | Sus scrofa TI:9823 None |  |  | ||||||
| INT1_DROME FlyBase» | 
 | 
 | IntS1 | Integrator complex subunit 1 | Drosophila melanogaster TI:7227 None |  |  |  | |||||
| K7ATZ5_PANTR Ensembl» | 
 | 
 | INTS1 | Integrator complex subunit 1 | Pan troglodytes TI:9598 None |  |  |  | |||||
| M3W832_FELCA Ensembl» | 
 | 
 | INTS1 | Integrator complex subunit 1 | Felis catus TI:9685 None |  |  |  | |||||
| W5LZC6_LEPOC Ensembl» | 
 | 
 | Integrator complex subunit 1 | Lepisosteus oculatus TI:7918 None |  |  |  | ||||||
| INT1_HUMAN Ensembl» | 
 | 
 | INTS1 | Integrator complex subunit 1 (Int1) | Homo sapiens TI:9606 None |  |  |  | |||||
| INT1_MOUSE Ensembl» | 
 | 
 | Ints1 | Integrator complex subunit 1 (Int1) | Mus musculus TI:10090 None |  |  |  | |||||
| INT1_DICDI dictyBase» | 
 | 
 | ints1 | Integrator complex subunit 1 homolog | Dictyostelium discoideum TI:44689 None |  |  |  | |||||
| A0A9J7M5D8_BRAFL CTD» | 
 | 
 | LOC118428625 | Integrator complex subunit 1-like | Branchiostoma floridae TI:7739 None |  |  | ||||||
| F1M8D7_RAT RGD» | 
 | 
 | Ints1 | Integrator complex subunit 1-like | Rattus norvegicus TI:10116 None |  |  | ||||||
| D6WAZ1_TRICA EnsemblMetazoa» | 
 | 
 | AUGUSTUS-3.0.2_01242 | Integrator complex subunit 1-like Protein | Tribolium castaneum TI:7070 None |  |  |  | |||||
| B7PNY5_IXOSC EnsemblMetazoa» | 
 | 
 | 8051185 | Integrator complex subunit, putative | Ixodes scapularis TI:6945 None |  |  |  | |||||
| A8Y1I6_CAEBR WormBase» | 
 | 
 | ints-1 | Protein CBG22096 | Caenorhabditis briggsae TI:6238 None |  |  |  | |||||
| A0A2R6W2Z2_MARPO EnsemblPlants» | 
 | 
 | MARPO_0170s0022 | Uncharacterized protein | Marchantia polymorpha TI:3197 None |  |  |  | |||||
| A0A2R6WZA1_MARPO EnsemblPlants» | 
 | 
 | MARPO_0046s0006 | Uncharacterized protein | Marchantia polymorpha TI:3197 None |  |  |  | |||||
| A0A2R6XUY4_MARPO EnsemblPlants» | 
 | 
 | MARPO_0001s0008 | Uncharacterized protein | Marchantia polymorpha TI:3197 None |  |  |  | |||||
| A7TCK4_NEMVE EnsemblMetazoa» | 
 | 
 | NEMVEDRAFT_v1g225280 | Uncharacterized protein | Nematostella vectensis TI:45351 None |  |  |  | |||||
| E9GHA6_DAPPU EnsemblMetazoa» | 
 | 
 | DAPPUDRAFT_242719 | Uncharacterized protein | Daphnia pulex TI:6669 None |  |  |  | |||||
| E9GHA8_DAPPU EnsemblMetazoa» | 
 | 
 | DAPPUDRAFT_317902 | Uncharacterized protein | Daphnia pulex TI:6669 None |  |  |  | |||||
| E9GV12_DAPPU EnsemblMetazoa» | 
 | 
 | DAPPUDRAFT_306111 | Uncharacterized protein | Daphnia pulex TI:6669 None |  |  |  | |||||
| E9HAG2_DAPPU EnsemblMetazoa» | 
 | 
 | DAPPUDRAFT_111914 | Uncharacterized protein | Daphnia pulex TI:6669 None |  |  |  | |||||
| E9HJE9_DAPPU EnsemblMetazoa» | 
 | 
 | DAPPUDRAFT_260637 | Uncharacterized protein | Daphnia pulex TI:6669 None |  |  |  | |||||
| E9HJH3_DAPPU EnsemblMetazoa» | 
 | 
 | DAPPUDRAFT_260581 | Uncharacterized protein | Daphnia pulex TI:6669 None |  |  |  | |||||
| E9HJK6_DAPPU EnsemblMetazoa» | 
 | 
 | DAPPUDRAFT_330438 | Uncharacterized protein | Daphnia pulex TI:6669 None |  |  |  | |||||
| E9HW27_DAPPU EnsemblMetazoa» | 
 | 
 | DAPPUDRAFT_334644 | Uncharacterized protein | Daphnia pulex TI:6669 None |  |  |  | |||||
| E9HW29_DAPPU EnsemblMetazoa» | 
 | 
 | DAPPUDRAFT_334645 | Uncharacterized protein | Daphnia pulex TI:6669 None |  |  |  | |||||
| E9HZN9_DAPPU EnsemblMetazoa» | 
 | 
 | DAPPUDRAFT_119856 | Uncharacterized protein | Daphnia pulex TI:6669 None |  |  |  | |||||
| H3H7V3_PHYRM EnsemblProtists» | 
 | 
 | Uncharacterized protein | Phytophthora ramorum TI:164328 None |  |  |  | ||||||