Standard knownness: 2.4; Custom knownness: None; Num. species: 33; Orthology database: Panther19.0; Protein members: 45
Molecular function: negative regulation of epidermal growth factor-activated receptor activity2009, 2024 negative regulation of epidermal growth factor receptor signaling pathway2009, 2024 endocytosis2021
Cellular component: early endosome membrane2009, 2018, 2024 cytosol2009, 2024 membrane2024 endosome2024 cytoplasm2024 early endosome2023
| Chordates: | 21/21 |  | 
| Echinoderms: | 0/0 | |
| Hemichordates: | 1/1 | |
| Annelids: | 1/1 | |
| Molluscs: | 0/0 | |
| Bryozoans: | 0/0 | |
| Platyhelminthes: | 0/0 | |
| Rotifers: | 0/0 | |
| Nematodes: | 3/3 | |
| Arthropods: | 5/5 | |
| Tardigrades: | 0/0 | |
| Placozoa: | 1/1 | |
| Cnidaria: | 0/1 | |
| Porifera: | 0/0 | |
| Choanoflagellates+: | 0/1 | |
| Dikarya: | 0/14 | |
| Fungi (other): | 0/1 | |
| Protozoa: | 1/3 | |
| Excavates: | 0/4 | |
| Harosa: | 0/4 | |
| Hacrobia: | 0/0 | |
| Plants: | 0/39 | |
| Archea: | 0/8 | |
| Bacteria: | 0/35 | 
Click here to switch to the previous version of the database.
| UniProt ID Organism DB» | Standard knownness | clustom knownness | Gene name | Description | Species [Key only] | GO terms | Seq. links | Protein domain links | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A0A1L8HKR8_XENLA Xenbase» | 
 | 
 | zfyve28a.S | Lateral signaling target protein 2 homolog isoform X1 | Xenopus laevis TI:8355 None |  |  | ||||||
| A0A1L8HT29_XENLA Xenbase» | 
 | 
 | zfyve28a.L | Lateral signaling target protein 2 homolog isoform X1 | Xenopus laevis TI:8355 None |  |  | ||||||
| A0A6I8S1S0_XENTR Xenbase» | 
 | 
 | zfyve28 | Lateral signaling target protein 2 homolog isoform X1 (Lateral-signaling target protein 2 homolog) | Xenopus tropicalis TI:8364 None |  |  | ||||||
| A0A7D9N0M7_XENTR Xenbase» | 
 | 
 | zfyve28 | Lateral signaling target protein 2 homolog isoform X1 (Lateral-signaling target protein 2 homolog) | Xenopus tropicalis TI:8364 None |  |  | ||||||
| A0A8J0UY72_XENLA Xenbase» | 
 | 
 | zfyve28b.S | Lateral signaling target protein 2 homolog isoform X1 | Xenopus laevis TI:8355 None |  |  | ||||||
| A0A8J1M0R8_XENLA Xenbase» | 
 | 
 | LOC108706519 | Lateral signaling target protein 2 homolog isoform X2 | Xenopus laevis TI:8355 None |  |  | ||||||
| LST2_XENTR Xenbase» | 
 | 
 | zfyve28 | Lateral signaling target protein 2 homolog (Zinc finger FYVE domain-containing protein 28) | Xenopus tropicalis TI:8364 None |  |  |  | |||||
| Q6DCE1_XENLA Xenbase» | 
 | 
 | zfyve28b.L | MGC83588 protein (Zinc finger FYVE-type containing 28 L homeolog) | Xenopus laevis TI:8355 None |  |  |  | |||||
| B3S384_TRIAD EnsemblMetazoa» | 
 | 
 | TRIADDRAFT_58631 | FYVE-type domain-containing protein | Trichoplax adhaerens TI:10228 None |  |  |  | |||||
| D6WZX8_TRICA EnsemblMetazoa» | 
 | 
 | AUGUSTUS-3.0.2_11751 | Lateral signaling target protein 2 homolog | Tribolium castaneum TI:7070 None |  |  |  | |||||
| A0A5G2R6B3_PIG Ensembl» | 
 | 
 | ZFYVE28 | Zinc finger FYVE-type containing 28 | Sus scrofa TI:9823 None |  |  | ||||||
| A0A7M7PBA1_STRPU EnsemblMetazoa» | 
 | 
 | FYVE-type domain-containing protein | Strongylocentrotus purpuratus TI:7668 None |  |  | |||||||
| A0A7M7REX6_STRPU EnsemblMetazoa» | 
 | 
 | FYVE-type domain-containing protein | Strongylocentrotus purpuratus TI:7668 None |  |  | |||||||
| A0A8I5ZMR3_RAT RGD» | 
 | 
 | Zfyve28 | Zinc finger FYVE-type containing 28 | Rattus norvegicus TI:10116 None |  |  | ||||||
| A0A2A6BCL7_PRIPA EnsemblMetazoa» | 
 | 
 | WBGene00095682 | Lst-2 | Pristionchus pacificus TI:54126 None |  |  |  | |||||
| K7D9W0_PANTR Ensembl» | 
 | 
 | ZFYVE28 | Zinc finger FYVE-type containing 28 (Zinc finger, FYVE domain containing 28) | Pan troglodytes TI:9598 None |  |  |  | |||||
| H2MMH2_ORYLA Ensembl» | 
 | 
 | zfyve28 | Zinc finger FYVE-type containing 28 | Oryzias latipes TI:8090 None |  |  | ||||||
| A0A6I8MYK6_ORNAN Ensembl» | 
 | 
 | ZFYVE28 | Zinc finger FYVE-type containing 28 | Ornithorhynchus anatinus TI:9258 None |  |  | ||||||
| A0A6I8MYZ9_ORNAN Ensembl» | 
 | 
 | FYVE-type domain-containing protein | Ornithorhynchus anatinus TI:9258 None |  |  | |||||||
| LST2_MOUSE Ensembl» | 
 | 
 | Zfyve28 | Lateral signaling target protein 2 homolog (Zinc finger FYVE domain-containing protein 28) | Mus musculus TI:10090 None |  |  |  | |||||
| F6XJ86_MONDO Ensembl» | 
 | 
 | LOC100031900 | Lateral signaling target protein 2 homolog | Monodelphis domestica TI:13616 None |  |  | ||||||
| F7AES7_MONDO Ensembl» | 
 | 
 | ZFYVE28 | Zinc finger FYVE-type containing 28 | Monodelphis domestica TI:13616 None |  |  | ||||||
| A0A1D5RBC7_MACMU Ensembl» | 
 | 
 | ZFYVE28 | Zinc finger FYVE-type containing 28 | Macaca mulatta TI:9544 None |  |  | ||||||
| W5MIY5_LEPOC Ensembl» | 
 | 
 | Zinc finger FYVE-type containing 28 | Lepisosteus oculatus TI:7918 None |  |  |  | ||||||
| W5N263_LEPOC Ensembl» | 
 | 
 | Lateral signaling target protein 2 homolog | Lepisosteus oculatus TI:7918 None |  |  |  | ||||||
| B7PAW0_IXOSC EnsemblMetazoa» | 
 | 
 | IscW_ISCW001994 | Lateral signaling target protein 2 homolog | Ixodes scapularis TI:6945 None |  |  |  | |||||
| LST2_HUMAN Ensembl» | 
 | 
 | ZFYVE28 | Lateral signaling target protein 2 homolog (hLst2) (Zinc finger FYVE domain-containing protein 28) | Homo sapiens TI:9606 None |  |  |  | |||||
| T1EJI1_HELRO EnsemblMetazoa» | 
 | 
 | 20196731 | FYVE-type domain-containing protein | Helobdella robusta TI:6412 None |  |  |  | |||||
| T1G6X3_HELRO EnsemblMetazoa» | 
 | 
 | 20216820 | Uncharacterized protein | Helobdella robusta TI:6412 None |  | |||||||
| A0A2I2YK91_GORGO Ensembl» | 
 | 
 | ZFYVE28 | Zinc finger FYVE-type containing 28 | Gorilla gorilla TI:9593 None |  |  |  | |||||
| A0A8V0Y2A5_CHICK Ensembl» | 
 | 
 | MXD3 | FYVE-type domain-containing protein | Gallus gallus TI:9031 None |  |  | ||||||
| A0A8V0Z1R1_CHICK Ensembl» | 
 | 
 | ZFYVE28 | Zinc finger FYVE-type containing 28 | Gallus gallus TI:9031 None |  |  | ||||||
| A0A5F5XN78_FELCA Ensembl» | 
 | 
 | ZFYVE28 | Zinc finger FYVE-type containing 28 | Felis catus TI:9685 None |  |  | ||||||
| A0A5F5PXS5_HORSE Ensembl» | 
 | 
 | ZFYVE28 | Zinc finger FYVE-type containing 28 | Equus caballus TI:9796 None | ||||||||
| LST2_DROME FlyBase» | 
 | 
 | CG6051 | Lateral signaling target protein 2 homolog | Drosophila melanogaster TI:7227 None |  |  |  | |||||
| Q55FL4_DICDI dictyBase» | 
 | 
 | DDB_G0268424 | FYVE-type domain-containing protein | Dictyostelium discoideum TI:44689 None |  |  |  | |||||
| E9G154_DAPPU EnsemblMetazoa» | 
 | 
 | DAPPUDRAFT_312971 | Lateral signaling target protein 2 homolog | Daphnia pulex TI:6669 None |  |  |  | |||||
| LST2_DANRE ZFIN» | 
 | 
 | zfyve28 | Lateral signaling target protein 2 homolog (Zinc finger FYVE domain-containing protein 28) | Danio rerio TI:7955 None |  |  |  | |||||
| A0A8I3NP27_CANLF Ensembl» | 
 | 
 | ZFYVE28 | Zinc finger FYVE-type containing 28 | Canis lupus TI:9612 None |  |  | ||||||
| LST2_CAEBR WormBase» | 
 | 
 | lst-2 | Lateral signaling target protein 2 | Caenorhabditis briggsae TI:6238 None |  |  |  | |||||
| LST2_CAEEL WormBase» | 
 | 
 | lst-2 | Lateral signaling target protein 2 | Caenorhabditis elegans TI:6239 None |  |  |  | |||||
| A0A9J7MNP7_BRAFL CTD» | 
 | 
 | LOC118414211 | Lateral signaling target protein 2 homolog | Branchiostoma floridae TI:7739 None | ||||||||
| F1MNN2_BOVIN Ensembl» | 
 | 
 | ZFYVE28 | Zinc finger FYVE-type containing 28 | Bos taurus TI:9913 None |  |  | ||||||
| LST2_ANOGA VEuPathDB» | 
 | 
 | AGAP003678 | Lateral signaling target protein 2 homolog | Anopheles gambiae TI:7165 None |  |  |  | |||||
| G1KEJ7_ANOCA Ensembl» | 
 | 
 | FYVE-type domain-containing protein | Anolis carolinensis TI:28377 None |  |  | |||||||