Collated Gene Ontology terms

Biological process: phosphatidylinositol transfer activity(2017, 2021, 2024) phosphatidylinositol binding(2017, 2021, 2024) insulin binding(2014, 2024) metal ion binding(2024) lipid binding(2024)

Molecular function: positive regulation of insulin secretion involved in cellular response to glucose stimulus2014, 2017, 2021, 2024 phospholipid transport2024 intermembrane lipid transfer2024 lipid transport2024

Cellular component: membrane2014, 2024 cytoplasmic side of apical plasma membrane2017, 2021, 2024 plasma membrane2012, 2023, 2024 endoplasmic reticulum-plasma membrane contact site2018, 2024 cortical endoplasmic reticulum2017, 2024 endoplasmic reticulum membrane2024 endoplasmic reticulum2024 nucleus2007 cytosol2008

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
A0A0G2L2I7_DANRE
ZFIN»
0.0
c2cd2 C2 calcium-dependent domain-containing 2 (C2
domain-containing protein 2 isoform X1)		 Danio rerio
TI:7955 None
 
A0A1L8FLG0_XENLA
Xenbase»
0.0
c2cd2l.L Phospholipid transfer protein C2CD2L Xenopus laevis
TI:8355 None
   
A0A1L8HCD6_XENLA
Xenbase»
0.0
c2cd2.L C2 domain-containing protein 2 Xenopus laevis
TI:8355 None
   
A0A2A6CGF1_PRIPA
EnsemblMetazoa»
0.0
WBGene00108208 C2 domain containing protein Pristionchus pacificus
TI:54126 None 		 
 
A0A2I2Z0U1_GORGO
Ensembl»
0.0
C2CD2 C2 calcium dependent domain containing 2 Gorilla gorilla
TI:9593 None 		 
 
A0A5F8GT54_MONDO
Ensembl»
0.0
C2CD2L C2CD2 like Monodelphis domestica
TI:13616 None
   
A0A6I8P974_ORNAN
Ensembl»
0.0
C2 domain-containing protein Ornithorhynchus anatinus
TI:9258 None 		     
A0A6I8PCE7_ORNAN
Ensembl»
0.0
C2CD2L C2CD2 like Ornithorhynchus anatinus
TI:9258 None
   
A0A6I8RED4_XENTR
Xenbase»
0.0
c2cd2 C2 calcium-dependent domain containing
2 (C2 domain-containing protein 2)		 Xenopus tropicalis
TI:8364 None
   
A0A7M7N9Y4_STRPU
EnsemblMetazoa»
0.0
C2 domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A8I3MVN8_CANLF
Ensembl»
0.0
C2CD2L C2CD2 like Canis lupus
TI:9612 None
   
A0A8I3QMY8_CANLF
Ensembl»
0.0
C2CD2 C2 calcium dependent domain containing 2 Canis lupus
TI:9612 None
   
A0A8J0UJD5_XENLA
Xenbase»
0.0
c2cd2.S C2 domain-containing protein 2 isoform X1 Xenopus laevis
TI:8355 None
   
A0A8M2BJ64_DANRE
CTD»
1.5
c2cd2l Phospholipid transfer protein C2CD2L isoform X1 Danio rerio
TI:7955 None
   
A0A8V0YBE3_CHICK
Ensembl»
0.0
C2CD2 C2 calcium dependent domain containing 2 Gallus gallus
TI:9031 None
   
A0A8V0ZZD2_CHICK
Ensembl»
0.0
C2CD2L C2CD2 like Gallus gallus
TI:9031 None 		     
A0A9J7LDV6_BRAFL
CTD»
0.0
LOC118418988 Phospholipid transfer protein
C2CD2L-like isoform X1		 Branchiostoma floridae
TI:7739 None
   
A0A9J7MV72_BRAFL
CTD»
0.0
LOC118419031 C2 domain-containing protein 2-like Branchiostoma floridae
TI:7739 None
   
A0NGL2_ANOGA
EnsemblMetazoa»
0.0
4577642 AGAP012190-PA Anopheles gambiae
TI:7165 None
 
A6IQH6_RAT
RGD»
0.0
C2cd2 C2 calcium-dependent domain containing 2 Rattus norvegicus
TI:10116 None
 
A7SY97_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g248059 SMP-LTD domain-containing protein Nematostella vectensis
TI:45351 None
 
A7SY99_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g248060 Phorbol-ester/DAG-type domain-containing protein Nematostella vectensis
TI:45351 None
 
A7Z071_BOVIN
Ensembl»
0.0
C2CD2L C2CD2 like (C2CD2L protein) Bos taurus
TI:9913 None
 
A8XJL6_CAEBR
WormBase»
0.0
CBG14248 CBG_14248 Protein CBG14248 Caenorhabditis briggsae
TI:6238 None
 
A9UYK9_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_25161 C2 domain-containing protein Monosiga brevicollis
TI:81824 None
 
B3S7K7_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_60201 C2 domain-containing protein Trichoplax adhaerens
TI:10228 None 		 
 
B7PJX4_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW017806 Phorbol-ester/DAG-type domain-containing protein Ixodes scapularis
TI:6945 None
 
B7YZL3_DROME
FlyBase»
0.0
10737 Uncharacterized protein, isoform T Drosophila melanogaster
TI:7227 None
 
C2C2L_HUMAN
Ensembl»
3.9
C2CD2L Phospholipid transfer protein C2CD2L (C2 domain-containing
protein 2-like) (C2CD2-like) (Transmembrane protein 24)		 Homo sapiens
TI:9606 None
 
C2C2L_MOUSE
Ensembl»
3.1
C2cd2l Phospholipid transfer protein C2CD2L (C2
domain-containing protein 2-like) (Transmembrane protein 24)		 Mus musculus
TI:10090 None
 
C2CD2_HUMAN
Ensembl»
0.0
C2CD2 C2 domain-containing protein
2 (Transmembrane protein 24-like)		 Homo sapiens
TI:9606 None
 
C2CD2_MOUSE
Ensembl»
0.0
C2cd2 C2 domain-containing protein 2 Mus musculus
TI:10090 None
 
D6WH87_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_02505 Uncharacterized protein Tribolium castaneum
TI:7070 None
 
E9HF17_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_328892 Phorbol-ester/DAG-type domain-containing protein Daphnia pulex
TI:6669 None
 
F1SAH4_PIG
Ensembl»
0.0
C2CD2L C2CD2 like Sus scrofa
TI:9823 None
   
F6TXG0_MACMU
Ensembl»
0.0
C2CD2L C2 domain-containing protein 2-like (C2CD2 like) Macaca mulatta
TI:9544 None
 
F6VVC6_HORSE
Ensembl»
0.0
C2CD2 C2 calcium dependent domain containing 2 Equus caballus
TI:9796 None
   
F6YCQ4_CIOIN
Ensembl»
0.0
LOC100176306 Uncharacterized LOC100176306 Ciona intestinalis
TI:7719 None
 
F6YZN9_XENTR
Xenbase»
0.0
c2cd2l C2CD2-like (Phospholipid transfer
protein C2CD2L isoform X1)		 Xenopus tropicalis
TI:8364 None
   
F7EUW3_RAT
RGD»
3.5
C2cd2l C2CD2-like Rattus norvegicus
TI:10116 None
   
F7F447_MACMU
Ensembl»
0.0
C2CD2 C2 calcium dependent domain containing 2
(C2 domain-containing protein 2 isoform 1)		 Macaca mulatta
TI:9544 None 		 
 
G1KBP8_ANOCA
Ensembl»
0.0
C2CD2 C2 calcium dependent domain containing 2 Anolis carolinensis
TI:28377 None
   
G3QYG7_GORGO
Ensembl»
0.0
C2CD2L C2CD2 like Gorilla gorilla
TI:9593 None
 
H2KYE1_CAEEL
WormBase»
0.0
tmem-24 C2 domain-containing protein Caenorhabditis elegans
TI:6239 None
 
H2LTL0_ORYLA
Ensembl»
0.0
c2cd2l C2CD2 like Oryzias latipes
TI:8090 None
   
H2MAZ7_ORYLA
Ensembl»
0.0
c2cd2 C2 calcium dependent domain containing 2 Oryzias latipes
TI:8090 None 		     
H2QL21_PANTR
Ensembl»
0.0
C2CD2 C2 calcium-dependent domain containing 2 Pan troglodytes
TI:9598 None 		 
 
H2R0L2_PANTR
Ensembl»
0.0
C2CD2L C2CD2-like Pan troglodytes
TI:9598 None
 
I3L9E6_PIG
Ensembl»
0.0
C2CD2 C2 calcium dependent domain containing 2
(C2 domain-containing protein 2 isoform 1)		 Sus scrofa
TI:9823 None
 
M3VW38_FELCA
Ensembl»
0.0
C2CD2L C2CD2 like Felis catus
TI:9685 None
 
M3WHE8_FELCA
Ensembl»
0.0
C2CD2 C2 calcium dependent domain containing 2 Felis catus
TI:9685 None
 
T1FPU7_HELRO
EnsemblMetazoa»
0.0
20210844 C2 domain-containing protein Helobdella robusta
TI:6412 None 		 
 
W5M7Z2_LEPOC
Ensembl»
0.0
C2cd2 like Lepisosteus oculatus
TI:7918 None
 
W5MAX7_LEPOC
Ensembl»
0.0
C2 calcium dependent domain containing 2 Lepisosteus oculatus
TI:7918 None