Cluster UKP09570
- PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY G MEMBER 7
Standard knownness: 5.0; Custom knownness: None; Num. species: 37; Orthology database: Panther19.0; Protein members: 74
Collated Gene Ontology terms
Molecular function:
Rho protein signal transduction2020, 2024
endothelial cell migration2007, 2020, 2024
intracellular signal transduction2024
blood vessel endothelial cell migration2009, 2024
angiogenesis2009, 2024
endothelial cell chemotaxis2013
regulation protein catabolic process at presynapse2024
signal transduction2024
regulation of small GTPase mediated signal transduction2024
positive regulation of Rho protein signal transduction2013
positive regulation of I-kappaB kinase/NF-kappaB signaling2004
imaginal disc-derived leg morphogenesis2012
gastrulation2010
Cellular component:
plasma membrane2007, 2020, 2024
endocytic vesicle2013, 2020, 2024
axon2020, 2024
lamellipodium2013, 2024
cytoplasm2013, 2024
cell-cell junction2013
perinuclear region of cytoplasm2024
cell projection2024
anchoring junction2024
presynapse2022, 2024
synapse2022
membrane2024
cytosol2023
Phylogenetic distribution
| Chordates: | 22/21 |  |
| Echinoderms: | 0/0 | |
| Hemichordates: | 1/1 | |
| Annelids: | 1/1 | |
| Molluscs: | 0/0 | |
| Bryozoans: | 0/0 | |
| Platyhelminthes: | 0/0 | |
| Rotifers: | 0/0 | |
| Nematodes: | 3/3 | |
| Arthropods: | 5/5 | |
| Tardigrades: | 0/0 | |
| Placozoa: | 1/1 | |
| Cnidaria: | 1/1 | |
| Porifera: | 0/0 | |
| Choanoflagellates+: | 0/1 | |
| Dikarya: | 0/14 | |
| Fungi (other): | 0/1 | |
| Protozoa: | 3/3 | |
| Excavates: | 0/4 | |
| Harosa: | 0/4 | |
| Hacrobia: | 0/0 | |
| Plants: | 0/39 | |
| Archea: | 0/8 | |
| Bacteria: | 0/35 |
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Proteins
| UniProt ID Organism DB» |
Standard knownness | clustom knownness | Gene name | Description | Species [Key only] | GO terms | Seq. links | Protein domain links | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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F1R1Q2_DANRE ZFIN» |
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plekhg5a | Pleckstrin homology domain-containing family G member 5 isoform X1 (Pleckstrin homology domain-containing, family G (with RhoGef domain) member 5a) |
Danio rerio TI:7955 None |
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A0A0G2L933_DANRE ZFIN» |
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plekhg5b | Pleckstrin homology domain-containing family G member 5-like isoform X1 (Pleckstrin homology domain-containing, family G (with RhoGef domain) member 5b) |
Danio rerio TI:7955 None |
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PKHG5_MOUSE Ensembl» |
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Plekhg5 | Pleckstrin homology domain-containing family G member 5 (PH domain-containing family G member 5) (Synectin-binding RhoA exchange factor) (SYX) |
Mus musculus TI:10090 None |
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PKHG5_HUMAN Ensembl» |
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PLEKHG5 | Pleckstrin homology domain-containing family G member 5 (PH domain-containing family G member 5) (Guanine nucleotide exchange factor 720) (GEF720) |
Homo sapiens TI:9606 None |
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PKHG5_RAT RGD» |
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Plekhg5 | Pleckstrin homology domain-containing family G member 5 (PH domain-containing family G member 5) (Neuronal RhoA GEF protein) (Transcript highly enriched in cortex and hippocampus) |
Rattus norvegicus TI:10116 None |
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Q9VW85_DROME FlyBase» |
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CG13812 | Uncharacterized protein, isoform C |
Drosophila melanogaster TI:7227 None |
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A0A8M3ATA9_DANRE CTD» |
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plekhg6 | Pleckstrin homology domain-containing family G member 6 isoform X1 |
Danio rerio TI:7955 None |
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S6EZU2_CAEEL WormBase» |
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rhgf-2 | DH domain-containing protein |
Caenorhabditis elegans TI:6239 None |
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A8HAL3_DANRE ZFIN» |
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si:ch211-276p10.1 | Pleckstrin homology domain-containing family G member 7 (Pleckstrin homology domain-containing, family G (with RhoGef domain) member 7) |
Danio rerio TI:7955 None |
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F1P129_CHICK Ensembl» |
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PLEKHG7 | Pleckstrin homology and RhoGEF domain containing G7 |
Gallus gallus TI:9031 None |
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PKHG7_HUMAN Ensembl» |
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PLEKHG7 | Pleckstrin homology domain-containing family G member 7 (PH domain-containing family G member 7) |
Homo sapiens TI:9606 None |
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Y6504_DICDI dictyBase» |
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DDB_G0289917 | Uncharacterized protein DDB_G0289917 |
Dictyostelium discoideum TI:44689 None |
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A0A1D5Q4S3_MACMU Ensembl» |
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PLEKHG7 | Pleckstrin homology and RhoGEF domain containing G7 |
Macaca mulatta TI:9544 None |
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A0A1L8GUP4_XENLA Xenbase» |
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plekhg7.S | Uncharacterized protein plekhg7.S isoform X1 |
Xenopus laevis TI:8355 None |
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A0A1L8GYC9_XENLA Xenbase» |
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plekhg7.L | Pleckstrin homology domain-containing family G member 5 |
Xenopus laevis TI:8355 None |
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A0A1S4H437_ANOGA EnsemblMetazoa» |
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Uncharacterized protein |
Anopheles gambiae TI:7165 None |
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A0A2A6BM49_PRIPA EnsemblMetazoa» |
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WBGene00096248 | Pleckstrin homology domain containing protein |
Pristionchus pacificus TI:54126 None |
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A0A2I3RX28_PANTR Ensembl» |
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PLEKHG7 | Pleckstrin homology and RhoGEF domain containing G7 |
Pan troglodytes TI:9598 None |
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A0A5F5PR54_HORSE Ensembl» |
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PLEKHG5 | Pleckstrin homology and RhoGEF domain containing G5 |
Equus caballus TI:9796 None |
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A0A5F8HAX0_MONDO Ensembl» |
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PLEKHG5 | Pleckstrin homology and RhoGEF domain containing G5 |
Monodelphis domestica TI:13616 None |
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A0A5G2R4N6_PIG Ensembl» |
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PLEKHG5 | Pleckstrin homology and RhoGEF domain containing G5 |
Sus scrofa TI:9823 None |
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A0A6I8PLU1_ORNAN Ensembl» |
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PLEKHG5 | Pleckstrin homology and RhoGEF domain containing G5 |
Ornithorhynchus anatinus TI:9258 None |
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A0A6I8QW21_XENTR Xenbase» |
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plekhg7 | Pleckstrin homology and RhoGEF domain-containing G7 (Pleckstrin homology domain-containing family G member 7) |
Xenopus tropicalis TI:8364 None |
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A0A6I8SU90_XENTR Xenbase» |
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plekhg5 | Pleckstrin homology and RhoGEF domain containing G5 (Pleckstrin homology domain-containing family G member 5 isoform X1) |
Xenopus tropicalis TI:8364 None |
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A0A7M7N0Z3_STRPU EnsemblMetazoa» |
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DH domain-containing protein |
Strongylocentrotus purpuratus TI:7668 None |
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A0A7M7PP29_STRPU EnsemblMetazoa» |
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Uncharacterized protein |
Strongylocentrotus purpuratus TI:7668 None |
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A0A7M7PWB4_STRPU EnsemblMetazoa» |
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Uncharacterized protein |
Strongylocentrotus purpuratus TI:7668 None |
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A0A7M7SZH1_STRPU EnsemblMetazoa» |
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DH domain-containing protein |
Strongylocentrotus purpuratus TI:7668 None |
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A0A8I3PT13_CANLF Ensembl» |
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PLEKHG5 | Pleckstrin homology and RhoGEF domain containing G5 |
Canis lupus TI:9612 None |
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A0A8J0TGE2_XENLA Xenbase» |
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plekhg5.S | Pleckstrin homology domain-containing family G member 5 isoform X1 |
Xenopus laevis TI:8355 None |
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A0A8J1L723_XENLA Xenbase» |
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plekhg5.L | Pleckstrin homology domain-containing family G member 5 isoform X1 |
Xenopus laevis TI:8355 None |
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A0A8M9P7M0_DANRE CTD» |
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LOC110438497 | Pleckstrin homology domain-containing family G member 6-like |
Danio rerio TI:7955 None |
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A0A8V0Z9W1_CHICK Ensembl» |
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PLEKHG5 | Pleckstrin homology and RhoGEF domain containing G5 |
Gallus gallus TI:9031 None |
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A0A9J7MFD0_BRAFL CTD» |
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LOC118431175 | Pleckstrin homology domain-containing family G member 5-like |
Branchiostoma floridae TI:7739 None |
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A0A9J7MQF3_BRAFL CTD» |
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LOC118415203 | Uncharacterized protein LOC118415203 isoform X1 |
Branchiostoma floridae TI:7739 None |
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A7RG07_NEMVE EnsemblMetazoa» |
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NEMVEDRAFT_v1g237981 | Pleckstrin homology domain-containing family G member 7 |
Nematostella vectensis TI:45351 None |
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A7S9N2_NEMVE EnsemblMetazoa» |
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NEMVEDRAFT_v1g243788 | Pleckstrin homology domain-containing family G member 5 |
Nematostella vectensis TI:45351 None |
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A8WZ74_CAEBR WormBase» |
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prhg-1 | Protein CBG05122 |
Caenorhabditis briggsae TI:6238 None |
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A8XTC0_CAEBR WormBase» |
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rhgf-2 | Protein CBR-RHGF-2 |
Caenorhabditis briggsae TI:6238 None |
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B3RZI4_TRIAD EnsemblMetazoa» |
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TRIADDRAFT_64013 | DH domain-containing protein |
Trichoplax adhaerens TI:10228 None |
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B3S744_TRIAD EnsemblMetazoa» |
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TRIADDRAFT_60035 | DH domain-containing protein |
Trichoplax adhaerens TI:10228 None |
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B7Q3L1_IXOSC EnsemblMetazoa» |
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IscW_ISCW008875 | Rho guanine exchange factor, putative |
Ixodes scapularis TI:6945 None |
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B7Q8E5_IXOSC EnsemblMetazoa» |
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IscW_ISCW010836 | DH domain-containing protein |
Ixodes scapularis TI:6945 None |
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C4LYA1_ENTH1 EnsemblProtists» |
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EHI_166990 | DH domain-containing protein |
Entamoeba histolytica TI:5759 None |
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C4M177_ENTH1 EnsemblProtists» |
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EHI_188030 | DH domain-containing protein |
Entamoeba histolytica TI:5759 None |
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D6WMV8_TRICA EnsemblMetazoa» |
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AUGUSTUS-3.0.2_14600 | DH domain-containing protein |
Tribolium castaneum TI:7070 None |
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E9FTQ3_DAPPU EnsemblMetazoa» |
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DAPPUDRAFT_95014 | DH domain-containing protein |
Daphnia pulex TI:6669 None |
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F1A476_DICPU EnsemblProtists» |
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DICPUDRAFT_84941 | Uncharacterized protein |
Dictyostelium purpureum TI:5786 None |
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F1MPJ6_BOVIN Ensembl» |
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PLEKHG5 | Pleckstrin homology and RhoGEF domain containing G5 |
Bos taurus TI:9913 None |
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F6TBV6_CIOIN Ensembl» |
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DH domain-containing protein |
Ciona intestinalis TI:7719 None |
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F6U0H1_MACMU Ensembl» |
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PLEKHG5 | Pleckstrin homology and RhoGEF domain containing G5 |
Macaca mulatta TI:9544 None |
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F7C6M3_ORNAN Ensembl» |
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Pleckstrin homology and RhoGEF domain containing G7 |
Ornithorhynchus anatinus TI:9258 None |
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F7DNX0_HORSE Ensembl» |
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PLEKHG7 | Pleckstrin homology and RhoGEF domain containing G7 |
Equus caballus TI:9796 None |
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F7F9Z4_MONDO Ensembl» |
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PLEKHG7 | Pleckstrin homology and RhoGEF domain containing G7 |
Monodelphis domestica TI:13616 None |
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G1KMA5_ANOCA Ensembl» |
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PLEKHG7 | Pleckstrin homology and RhoGEF domain containing G7 |
Anolis carolinensis TI:28377 None |
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G3RDZ2_GORGO Ensembl» |
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Pleckstrin homology and RhoGEF domain containing G7 |
Gorilla gorilla TI:9593 None |
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G3SF04_GORGO Ensembl» |
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PLEKHG5 | Pleckstrin homology and RhoGEF domain containing G5 |
Gorilla gorilla TI:9593 None |
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H2L0P5_CAEEL WormBase» |
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prhg-1 | Pleckstrin homology domain-containing family G member 7 |
Caenorhabditis elegans TI:6239 None |
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H2M6T9_ORYLA Ensembl» |
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plekhg7 | Pleckstrin homology and RhoGEF domain containing G7 |
Oryzias latipes TI:8090 None |
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H2MA02_ORYLA Ensembl» |
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plekhg6 | Pleckstrin homology and RhoGEF domain containing G6 |
Oryzias latipes TI:8090 None |
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H2MYE3_ORYLA Ensembl» |
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plekhg5 | Pleckstrin homology and RhoGEF domain containing G5 |
Oryzias latipes TI:8090 None |
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H2R042_PANTR Ensembl» |
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PLEKHG5 | Pleckstrin homology and RhoGEF domain containing G5 |
Pan troglodytes TI:9598 None |
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M3VV66_FELCA Ensembl» |
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PLEKHG5 | Pleckstrin homology and RhoGEF domain containing G5 |
Felis catus TI:9685 None |
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T1EP78_HELRO EnsemblMetazoa» |
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20198378 | DH domain-containing protein |
Helobdella robusta TI:6412 None |
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T1EP79_HELRO EnsemblMetazoa» |
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20198379 | Uncharacterized protein |
Helobdella robusta TI:6412 None |
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T1EQC9_HELRO EnsemblMetazoa» |
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20198779 | PH domain-containing protein |
Helobdella robusta TI:6412 None |
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T1EQD0_HELRO EnsemblMetazoa» |
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20198780 | DH domain-containing protein |
Helobdella robusta TI:6412 None |
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T1EQU7_HELRO EnsemblMetazoa» |
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20198947 | Uncharacterized protein |
Helobdella robusta TI:6412 None |
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T1F8Y3_HELRO EnsemblMetazoa» |
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20205282 | DH domain-containing protein |
Helobdella robusta TI:6412 None |
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T1FGL0_HELRO EnsemblMetazoa» |
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20207959 | DH domain-containing protein |
Helobdella robusta TI:6412 None |
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T1FU70_HELRO EnsemblMetazoa» |
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20212366 | DH domain-containing protein |
Helobdella robusta TI:6412 None |
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W5M4N7_LEPOC Ensembl» |
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Pleckstrin homology and RhoGEF domain containing G5 |
Lepisosteus oculatus TI:7918 None |
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W5MIT9_LEPOC Ensembl» |
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DH domain-containing protein |
Lepisosteus oculatus TI:7918 None |
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W5NDV9_LEPOC Ensembl» |
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Pleckstrin homology domain containing, family G (with RhoGef domain) member 7 |
Lepisosteus oculatus TI:7918 None |
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