Collated Gene Ontology terms

Biological process: translation elongation factor activity(2025)

Molecular function: positive regulation of DNA damage response, signal transduction by p53 class mediator2005, 2013, 2021, 2025 translation2025 positive regulation of cellular senescence2016, 2025 positive regulation of apoptotic process2005, 2025 negative regulation of cell population proliferation2005, 2025 translational elongation2025 positive regulation of apoptotic signaling pathway2013 cellular response to leukemia inhibitory factor2017 tRNA aminoacylation for protein translation2025

Cellular component: aminoacyl-tRNA synthetase multienzyme complex2005, 2017, 2021, 2025 cytoplasm2005, 2021, 2025 nucleus2005, 2021, 2025 protein-containing complex2025 cytosol2013, 2017, 2025 nucleoplasm2024, 2025 intracellular protein-containing complex2025 catalytic complex2025 nucleolus2025

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
MCA3_MOUSE
Ensembl»
4.5
Eef1e1 Eukaryotic translation elongation factor 1 epsilon-1 (Elongation
factor p18) (Multisynthase complex auxiliary component p18)		 Mus musculus
TI:10090 None
 
A0A8I6A4G8_RAT
RGD»
3.0
Eef1e1 Eukaryotic translation elongation
factor 1 epsilon 1		 Rattus norvegicus
TI:10116 None
   
MCA3_HUMAN
Ensembl»
2.9
EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 (Aminoacyl tRNA synthetase complex-interacting
multifunctional protein 3) (Elongation factor p18) (Multisynthase complex auxiliary component p18)		 Homo sapiens
TI:9606 None
 
Q8MKK1_DROME
FlyBase»
0.5
AIMP3 AaRS-interacting multifunctional
protein 3 (RH09246p)		 Drosophila melanogaster
TI:7227 None
 
A0A139WEF6_TRICA
CTD»
0.0
AUGUSTUS-3.0.2_33706 Eukaryotic translation elongation
factor 1 epsilon-1-like Protein		 Tribolium castaneum
TI:7070 None
 
A0A286ZWJ2_PIG
Ensembl»
0.0
EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 (Elongation
factor p18) (Multisynthase complex auxiliary component p18)		 Sus scrofa
TI:9823 None
 
A0A2I2Y7B6_GORGO
Ensembl»
0.0
GST C-terminal domain-containing protein Gorilla gorilla
TI:9593 None
 
A0A3B3I7D0_ORYLA
Ensembl»
0.0
EEF1E1 Eukaryotic translation elongation
factor 1 epsilon 1		 Oryzias latipes
TI:8090 None
   
A0A5F8GMH2_MONDO
Ensembl»
0.0
EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 (Elongation
factor p18) (Multisynthase complex auxiliary component p18)		 Monodelphis domestica
TI:13616 None
   
A0A7M7RCQ1_STRPU
EnsemblMetazoa»
0.0
GST C-terminal domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A803T737_ANOCA
Ensembl»
0.0
EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 (Elongation
factor p18) (Multisynthase complex auxiliary component p18)		 Anolis carolinensis
TI:28377 None
   
A0A8I3P666_CANLF
Ensembl»
0.0
EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 (Elongation
factor p18) (Multisynthase complex auxiliary component p18)		 Canis lupus
TI:9612 None
   
A0A8V0YGI8_CHICK
Ensembl»
0.0
EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 (Elongation
factor p18) (Multisynthase complex auxiliary component p18)		 Gallus gallus
TI:9031 None
   
A0A9L0S684_HORSE
Ensembl»
0.0
EEF1E1 Eukaryotic translation elongation
factor 1 epsilon 1		 Equus caballus
TI:9796 None
   
A0BEQ0_PARTE
neXtProt»
0.0
GSPATT00028050001 GST C-terminal domain-containing protein Paramecium tetraurelia
TI:5888 None
 
A0D7Y5_PARTE
neXtProt»
0.0
GSPATT00014119001 GST C-terminal domain-containing protein Paramecium tetraurelia
TI:5888 None
 
A7RVG0_NEMVE
neXtProt»
0.0
NEMVEDRAFT_v1g240962 GST C-terminal domain-containing protein Nematostella vectensis
TI:45351 None
 
A9JSA9_XENTR
Xenbase»
0.0
eef1e1 Eukaryotic translation elongation factor 1 epsilon-1 (Elongation
factor p18) (Multisynthase complex auxiliary component p18)		 Xenopus tropicalis
TI:8364 None
 
B3S0Y2_TRIAD
CTD»
0.0
TRIADDRAFT_58127 Nuclear-export cofactor Arc1-like
N-terminal domain-containing protein		 Trichoplax adhaerens
TI:10228 None
 
B7PH63_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW004346 Elongation factor 1 gamma, putative Ixodes scapularis
TI:6945 None
 
C3ZYB0_BRAFL
euHCVdb»
0.0
LOC118409680 Eukaryotic translation elongation
factor 1 epsilon-1-like		 Branchiostoma floridae
TI:7739 None
 
C9J1V9_HUMAN
Ensembl»
0.0
EEF1E1-BLOC1S5 EEF1E1-BLOC1S5 readthrough
(NMD candidate) (HCG2043275)		 Homo sapiens
TI:9606 None
 
F1QVE4_DANRE
ZFIN»
0.0
eef1e1 Eukaryotic translation elongation
factor 1 epsilon-1		 Danio rerio
TI:7955 None
 
F6TNV5_CIOIN
Ensembl»
0.0
LOC100184121 Eukaryotic translation elongation
factor 1 epsilon-1-like		 Ciona intestinalis
TI:7719 None
   
F6XYD6_ORNAN
Ensembl»
0.0
EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 (Elongation
factor p18) (Multisynthase complex auxiliary component p18)		 Ornithorhynchus anatinus
TI:9258 None
   
G3R2B5_GORGO
Ensembl»
0.0
EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 (Elongation
factor p18) (Multisynthase complex auxiliary component p18)		 Gorilla gorilla
TI:9593 None
 
H2QSA0_PANTR
Ensembl»
0.0
EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 (Elongation
factor p18) (Multisynthase complex auxiliary component p18)		 Pan troglodytes
TI:9598 None
 
H3GKN2_PHYRM
EnsemblProtists»
0.0
GST C-terminal domain-containing protein Phytophthora ramorum
TI:164328 None
 
Q3SZ15_BOVIN
Ensembl»
0.0
EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 (Elongation
factor p18) (Multisynthase complex auxiliary component p18)		 Bos taurus
TI:9913 None
 
Q5U5C0_XENLA
Xenbase»
0.0
eef1e1.L Eukaryotic translation elongation factor 1 epsilon-1 (Elongation
factor p18) (Multisynthase complex auxiliary component p18)		 Xenopus laevis
TI:8355 None
 
Q7Q7Z9_ANOGA
EnsemblMetazoa»
0.0
AgaP_AGAP004929 AGAP004929-PA Anopheles gambiae
TI:7165 None
 
T1G855_HELRO
EnsemblMetazoa»
0.0
20217252 GST C-terminal domain-containing protein Helobdella robusta
TI:6412 None
 
W5N6M5_LEPOC
Ensembl»
0.0
Eukaryotic translation elongation
factor 1 epsilon 1		 Lepisosteus oculatus
TI:7918 None