Collated Gene Ontology terms

Biological process: translation elongation factor activity(2025)

Molecular function: positive regulation of DNA damage response, signal transduction by p53 class mediator2005, 2013, 2021, 2025 translation2025 positive regulation of cellular senescence2016, 2025 positive regulation of apoptotic process2005, 2025 negative regulation of cell population proliferation2005, 2025 translational elongation2025 positive regulation of apoptotic signaling pathway2013 cellular response to leukemia inhibitory factor2017 tRNA aminoacylation for protein translation2025

Cellular component: aminoacyl-tRNA synthetase multienzyme complex2005, 2017, 2021, 2025 cytoplasm2005, 2021, 2025 nucleus2005, 2021, 2025 protein-containing complex2025 cytosol2013, 2017, 2025 nucleoplasm2024, 2025 intracellular protein-containing complex2025 catalytic complex2025 nucleolus2025

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
Q8MKK1_DROME
FlyBase»
0.5
AIMP3 AaRS-interacting multifunctional
protein 3 (RH09246p)		 Drosophila melanogaster
TI:7227 None
 
MCA3_MOUSE
Ensembl»
4.5
Eef1e1 Eukaryotic translation elongation factor 1 epsilon-1 (Elongation
factor p18) (Multisynthase complex auxiliary component p18)		 Mus musculus
TI:10090 None
 
MCA3_HUMAN
Ensembl»
2.9
EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 (Aminoacyl tRNA synthetase complex-interacting
multifunctional protein 3) (Elongation factor p18) (Multisynthase complex auxiliary component p18)		 Homo sapiens
TI:9606 None
 
F1QVE4_DANRE
ZFIN»
0.0
eef1e1 Eukaryotic translation elongation
factor 1 epsilon-1		 Danio rerio
TI:7955 None
 
C9J1V9_HUMAN
Ensembl»
0.0
EEF1E1-BLOC1S5 EEF1E1-BLOC1S5 readthrough
(NMD candidate) (HCG2043275)		 Homo sapiens
TI:9606 None
 
A0A8V0YGI8_CHICK
Ensembl»
0.0
EEF1E1 Eukaryotic translation elongation factor 1 epsilon-1 (Elongation
factor p18) (Multisynthase complex auxiliary component p18)		 Gallus gallus
TI:9031 None
   
A0A8I6A4G8_RAT
RGD»
3.0
Eef1e1 Eukaryotic translation elongation
factor 1 epsilon 1		 Rattus norvegicus
TI:10116 None