Standard knownness: 3.5; Custom knownness: None; Num. species: 31; Orthology database: Panther19.0; Protein members: 37
Molecular function: positive regulation of stress-activated MAPK cascade2013, 2018, 2024 rescue of stalled ribosome2023, 2024 ubiquitin-dependent protein catabolic process via the C-end degron rule pathway2021, 2023, 2024 protein ubiquitination2024 protein phosphorylation2024 phosphorylation2024 intracellular signal transduction2024 MAPK cascade2024
Cellular component: Cul2-RING ubiquitin ligase complex2013, 2021, 2023, 2024 cytoplasm2023, 2024 nucleoplasm2023, 2024 nucleus2024 membrane2024
| Chordates: | 21/21 | ![]()  | 
                   
                 
| Echinoderms: | 0/0 | |
| Hemichordates: | 1/1 | |
| Annelids: | 0/1 | |
| Molluscs: | 0/0 | |
| Bryozoans: | 0/0 | |
| Platyhelminthes: | 0/0 | |
| Rotifers: | 0/0 | |
| Nematodes: | 3/3 | |
| Arthropods: | 4/5 | |
| Tardigrades: | 0/0 | |
| Placozoa: | 1/1 | |
| Cnidaria: | 1/1 | |
| Porifera: | 0/0 | |
| Choanoflagellates+: | 0/1 | |
| Dikarya: | 0/14 | |
| Fungi (other): | 0/1 | |
| Protozoa: | 0/3 | |
| Excavates: | 0/4 | |
| Harosa: | 0/4 | |
| Hacrobia: | 0/0 | |
| Plants: | 0/39 | |
| Archea: | 0/8 | |
| Bacteria: | 0/35 | 
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| UniProt ID Organism DB»  | 
	    
        
          
            Standard knownness | clustom knownness | Gene name | Description | Species [Key only] | GO terms | Seq. links | Protein domain links | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 
        A0A803TKJ8_ANOCA Ensembl»  | 
        
          
  | 
        
          
  | 
        KLHDC10 | Kelch domain containing 10 | 
        Anolis carolinensis TI:28377 None  | 
        
          
           | 
        |||||||
| 
        Q7Q7V5_ANOGA EnsemblMetazoa»  | 
        
          
  | 
        
          
  | 
        1275829 | AGAP005004-PA | 
        Anopheles gambiae TI:7165 None  | 
        
          
           | 
        
          
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        |||||
| 
        KLD10_BOVIN Ensembl»  | 
        
          
  | 
        
          
  | 
        KLHDC10 | Kelch domain-containing protein 10 | 
        Bos taurus TI:9913 None  | 
        
          
           | 
        
          
           | 
        
          
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        |||||
| 
        A0A9J7L8D3_BRAFL CTD»  | 
        
          
  | 
        
          
  | 
        LOC118416880 | Kelch domain-containing protein 10-like | 
        Branchiostoma floridae TI:7739 None  | 
        
          
           | 
        |||||||
| 
        A8WQT3_CAEBR WormBase»  | 
        
          
  | 
        
          
  | 
        CBG01796 CBG_01796 | Protein CBG01796 | 
        Caenorhabditis briggsae TI:6238 None  | 
        
          
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        |||||
| 
        Q95PZ3_CAEEL WormBase»  | 
        
          
  | 
        
          
  | 
        CELE_Y67H2A.2 Y67H2A.2 | Kelch domain-containing protein 10 | 
        Caenorhabditis elegans TI:6239 None  | 
        
          
           | 
        
          
           | 
        
          
           | 
        |||||
| 
        A0A8I3P3N8_CANLF Ensembl»  | 
        
          
  | 
        
          
  | 
        KLHDC10 | Kelch domain containing 10 | 
        Canis lupus TI:9612 None  | 
        
          
           | 
        
          
           | 
        ||||||
| 
        F7A7N9_CIOIN Ensembl»  | 
        
          
  | 
        
          
  | 
        Kelch domain-containing protein | 
        Ciona intestinalis TI:7719 None  | 
        
          
           | 
        
          
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        |||||||
| 
        H2XT42_CIOIN Ensembl»  | 
        
          
  | 
        
          
  | 
        Uncharacterized protein | 
        Ciona intestinalis TI:7719 None  | 
        
          
           | 
        
          
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        |||||||
| 
        A0A8M2BBZ4_DANRE CTD»  | 
        
          
  | 
        
          
  | 
        klhdc10 | Kelch domain-containing protein 10 isoform X1 | 
        Danio rerio TI:7955 None  | 
        
          
           | 
        
          
           | 
        ||||||
| 
        KLD10_DROME FlyBase»  | 
        
          
  | 
        
          
  | 
        slim | Kelch domain-containing protein 10 homolog (Scruin like at the midline)  | 
        
        Drosophila melanogaster TI:7227 None  | 
        
          
           | 
        
          
           | 
        
          
           | 
        |||||
| 
        M3W057_FELCA Ensembl»  | 
        
          
  | 
        
          
  | 
        KLHDC10 | Kelch domain containing 10 | 
        Felis catus TI:9685 None  | 
        
          
           | 
        
          
           | 
        ||||||
| 
        A0A8V0XLK1_CHICK Ensembl»  | 
        
          
  | 
        
          
  | 
        KLHDC10 | Kelch domain containing 10 | 
        Gallus gallus TI:9031 None  | 
        
          
           | 
        |||||||
| 
        G3QEH2_GORGO Ensembl»  | 
        
          
  | 
        
          
  | 
        KLHDC10 | Kelch domain containing 10 | 
        Gorilla gorilla TI:9593 None  | 
        
          
           | 
        
          
           | 
        
          
           | 
        |||||
| 
        KLD10_HUMAN Ensembl»  | 
        
          
  | 
        
          
  | 
        KLHDC10 | Kelch domain-containing protein 10 | 
        Homo sapiens TI:9606 None  | 
        
          
           | 
        
          
           | 
        
          
           | 
        |||||
| 
        B7PD33_IXOSC EnsemblMetazoa»  | 
        
          
  | 
        
          
  | 
        IscW_ISCW017356 | Kelch repeat protein, putative | 
        Ixodes scapularis TI:6945 None  | 
        
          
           | 
        
          
           | 
        
          
           | 
        |||||
| 
        W5NGA1_LEPOC Ensembl»  | 
        
          
  | 
        
          
  | 
        Kelch domain containing 10 | 
        Lepisosteus oculatus TI:7918 None  | 
        
          
           | 
        
          
           | 
        
          
           | 
        ||||||
| 
        F7HLQ8_MACMU Ensembl»  | 
        
          
  | 
        
          
  | 
        KLHDC10 | Kelch domain containing 10 | 
        Macaca mulatta TI:9544 None  | 
        
          
           | 
        
          
           | 
        ||||||
| 
        A0A5F8GXV6_MONDO Ensembl»  | 
        
          
  | 
        
          
  | 
        KLHDC10 | Kelch domain containing 10 | 
        Monodelphis domestica TI:13616 None  | 
        
          
           | 
        
          
           | 
        ||||||
| 
        KLD10_MOUSE Ensembl»  | 
        
          
  | 
        
          
  | 
        Klhdc10 | Kelch domain-containing protein 10 | 
        Mus musculus TI:10090 None  | 
        
          
           | 
        
          
           | 
        
          
           | 
        |||||
| 
        A7SYI0_NEMVE EnsemblMetazoa»  | 
        
          
  | 
        
          
  | 
        NEMVEDRAFT_v1g194768 | Kelch domain-containing protein 10 | 
        Nematostella vectensis TI:45351 None  | 
        
          
           | 
        
          
           | 
        
          
           | 
        |||||
| 
        A0A6I8NK80_ORNAN Ensembl»  | 
        
          
  | 
        
          
  | 
        KLHDC10 | Kelch domain containing 10 | 
        Ornithorhynchus anatinus TI:9258 None  | 
        
          
           | 
        
          
           | 
        ||||||
| 
        H2M566_ORYLA Ensembl»  | 
        
          
  | 
        
          
  | 
        LOC101173702 | Kelch domain-containing protein 10-like | 
        Oryzias latipes TI:8090 None  | 
        
          
           | 
        
          
           | 
        ||||||
| 
        H2MHD7_ORYLA Ensembl»  | 
        
          
  | 
        
          
  | 
        klhdc10 | Kelch domain containing 10 | 
        Oryzias latipes TI:8090 None  | 
        
          
           | 
        
          
           | 
        ||||||
| 
        H2QVD2_PANTR Ensembl»  | 
        
          
  | 
        
          
  | 
        KLHDC10 | Kelch domain containing 10 | 
        Pan troglodytes TI:9598 None  | 
        
          
           | 
        
          
           | 
        
          
           | 
        |||||
| 
        A0A2A6CB46_PRIPA EnsemblMetazoa»  | 
        
          
  | 
        
          
  | 
        WBGene00277170 | Kelch repeat protein | 
        Pristionchus pacificus TI:54126 None  | 
        
          
           | 
        
          
           | 
        ||||||
| 
        KLD10_RAT RGD»  | 
        
          
  | 
        
          
  | 
        Klhdc10 | Kelch domain-containing protein 10 | 
        Rattus norvegicus TI:10116 None  | 
        
          
           | 
        
          
           | 
        
          
           | 
        |||||
| 
        A0A7M7MXN1_STRPU EnsemblMetazoa»  | 
        
          
  | 
        
          
  | 
        Kelch domain-containing protein 10 | 
        Strongylocentrotus purpuratus TI:7668 None  | 
        
          
           | 
        
          
           | 
        |||||||
| 
        A0A7M7PQC7_STRPU EnsemblMetazoa»  | 
        
          
  | 
        
          
  | 
        Uncharacterized protein | 
        Strongylocentrotus purpuratus TI:7668 None  | 
        
          
           | 
        
          
           | 
        |||||||
| 
        A0A7M7SSI0_STRPU EnsemblMetazoa»  | 
        
          
  | 
        
          
  | 
        Uncharacterized protein | 
        Strongylocentrotus purpuratus TI:7668 None  | 
        
          
           | 
        
          
           | 
        |||||||
| 
        A0A286ZWR0_PIG Ensembl»  | 
        
          
  | 
        
          
  | 
        KLHDC10 | Kelch domain containing 10 | 
        Sus scrofa TI:9823 None  | 
        
          
           | 
        
          
           | 
        ||||||
| 
        D6X316_TRICA EnsemblMetazoa»  | 
        
          
  | 
        
          
  | 
        AUGUSTUS-3.0.2_12522 | Kelch domain-containing protein 10 homolog-like Protein  | 
        
        Tribolium castaneum TI:7070 None  | 
        
          
           | 
        
          
           | 
        
          
           | 
        |||||
| 
        B3RUW1_TRIAD EnsemblMetazoa»  | 
        
          
  | 
        
          
  | 
        TRIADDRAFT_55434 | Kelch domain-containing protein 10 | 
        Trichoplax adhaerens TI:10228 None  | 
        
          
           | 
        
          
           | 
        
          
           | 
        |||||
| 
        A0A1L8GTR3_XENLA Xenbase»  | 
        
          
  | 
        
          
  | 
        klhdc10.S | Kelch domain-containing protein 10 | 
        Xenopus laevis TI:8355 None  | 
        
          
           | 
        
          
           | 
        ||||||
| 
        A0A8J0QRX9_XENTR Xenbase»  | 
        
          
  | 
        
          
  | 
        map3k4 | Mitogen-activated protein kinase kinase kinase 4 isoform X1  | 
        
        Xenopus tropicalis TI:8364 None  | 
        
          
           | 
        
          
           | 
        ||||||
| 
        KLD10_XENLA Xenbase»  | 
        
          
  | 
        
          
  | 
        klhdc10 | Kelch domain-containing protein 10 | 
        Xenopus laevis TI:8355 None  | 
        
          
           | 
        
          
           | 
        
          
           | 
        |||||
| 
        KLD10_XENTR Xenbase»  | 
        
          
  | 
        
          
  | 
        klhdc10 | Kelch domain-containing protein 10 | 
        Xenopus tropicalis TI:8364 None  | 
        
          
           | 
        
          
           | 
        
          
           | 
        |||||