Collated Gene Ontology terms

Biological process: RNA binding(2013, 2024)

Molecular function: mRNA processing2024 tRNA processing2005, 2013, 2024 termination of RNA polymerase II transcription, poly(A)-coupled2018, 2019, 2024 negative regulation of protein binding2018 co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway2023, 2024 cell adhesion2024 ribosomal large subunit biogenesis2021 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021 mRNA trans splicing, via spliceosome2016 mRNA 3'-end processing by stem-loop binding and cleavage2016
endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021 cilium movement involved in cell motility2024 cilium assembly2024

Cellular component: nucleus2009, 2017, 2018, 2024 mRNA cleavage and polyadenylation specificity factor complex2004, 2016, 2017, 2018, 2019, 2020, 2024 nucleoplasm2001, 2016, 2017, 2023, 2024 nuclear stress granule2016, 2024 cytoplasm2001, 2024 plasma membrane2023, 2024 nuclear body2017, 2024 cytosol2023, 2024 cytoskeleton2024 bicellular tight junction2024
tricellular tight junction2016 radial spoke2024 membrane2024 histone locus body2016 cilium2024 axoneme2024

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 3/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 2/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
SYMPK_HUMAN
Ensembl»
0.8
SYMPK Symplekin Homo sapiens
TI:9606 None
 
SYMPK_MOUSE
Ensembl»
0.5
Sympk Symplekin Mus musculus
TI:10090 None
 
PTA1_YEAST
SGD»
3.2
PTA1 Pre-tRNA-processing protein PTA1 Saccharomyces cerevisiae
TI:4932 None
 
SYMPK_DROME
FlyBase»
1.6
Sym Symplekin Drosophila melanogaster
TI:7227 None
 
A0A0G2K1E5_RAT
RGD»
0.0
Sympk Symplekin Rattus norvegicus
TI:10116 None
   
PTA1_SCHPO
PomBase»
1.5
pta1 mRNA cleavage and polyadenylation
specificity factor complex subunit pta1		 Schizosaccharomyces pombe
TI:4896 None
 
A0A0R4I9D6_DANRE
ZFIN»
0.0
sympk Symplekin (Symplekin isoform X1) Danio rerio
TI:7955 None
 
O16929_CAEEL
WormBase»
0.0
symk-1 DUF3453 domain-containing protein Caenorhabditis elegans
TI:6239 None
 
Q54PX4_DICDI
dictyBase»
0.0
sympk Symplekin Dictyostelium discoideum
TI:44689 None