Cluster UKP09437
- SYMPLEKIN-RELATED
Standard knownness: 3.2; Custom knownness: None; Num. species: 55; Orthology database: Panther19.0; Protein members: 60
Collated Gene Ontology terms
Molecular function:
mRNA processing2024
tRNA processing2005, 2013, 2024
termination of RNA polymerase II transcription, poly(A)-coupled2018, 2019, 2024
negative regulation of protein binding2018
co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway2023, 2024
cell adhesion2024
ribosomal large subunit biogenesis2021
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021
mRNA trans splicing, via spliceosome2016
mRNA 3'-end processing by stem-loop binding and cleavage2016
endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021
cilium movement involved in cell motility2024
cilium assembly2024
Cellular component:
nucleus2009, 2017, 2018, 2024
mRNA cleavage and polyadenylation specificity factor complex2004, 2016, 2017, 2018, 2019, 2020, 2024
nucleoplasm2001, 2016, 2017, 2023, 2024
nuclear stress granule2016, 2024
cytoplasm2001, 2024
plasma membrane2023, 2024
nuclear body2017, 2024
cytosol2023, 2024
cytoskeleton2024
bicellular tight junction2024
tricellular tight junction2016
radial spoke2024
membrane2024
histone locus body2016
cilium2024
axoneme2024
Phylogenetic distribution
| Chordates: | 20/21 |  |
| Echinoderms: | 0/0 | |
| Hemichordates: | 1/1 | |
| Annelids: | 1/1 | |
| Molluscs: | 0/0 | |
| Bryozoans: | 0/0 | |
| Platyhelminthes: | 0/0 | |
| Rotifers: | 0/0 | |
| Nematodes: | 3/3 | |
| Arthropods: | 5/5 | |
| Tardigrades: | 0/0 | |
| Placozoa: | 1/1 | |
| Cnidaria: | 1/1 | |
| Porifera: | 0/0 | |
| Choanoflagellates+: | 14/1 | |
| Dikarya: | 0/14 | |
| Fungi (other): | 0/1 | |
| Protozoa: | 2/3 | |
| Excavates: | 3/4 | |
| Harosa: | 2/4 | |
| Hacrobia: | 0/0 | |
| Plants: | 2/39 | |
| Archea: | 0/8 | |
| Bacteria: | 0/35 |
Click here to switch to the previous version of the database.
Proteins
| UniProt ID Organism DB» |
Standard knownness | clustom knownness | Gene name | Description | Species [Key only] | GO terms | Seq. links | Protein domain links | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
PTA1_YEAST SGD» |
|
|
PTA1 | Pre-tRNA-processing protein PTA1 |
Saccharomyces cerevisiae TI:4932 None |
|
|
|
|||||
|
SYMPK_DROME FlyBase» |
|
|
Sym | Symplekin |
Drosophila melanogaster TI:7227 None |
|
|
|
|||||
|
PTA1_SCHPO PomBase» |
|
|
pta1 | mRNA cleavage and polyadenylation specificity factor complex subunit pta1 |
Schizosaccharomyces pombe TI:4896 None |
|
|
|
|||||
|
SYMPK_HUMAN Ensembl» |
|
|
SYMPK | Symplekin |
Homo sapiens TI:9606 None |
|
|
|
|||||
|
SYMPK_MOUSE Ensembl» |
|
|
Sympk | Symplekin |
Mus musculus TI:10090 None |
|
|
|
|||||
|
A0A0G2K1E5_RAT RGD» |
|
|
Sympk | Symplekin |
Rattus norvegicus TI:10116 None |
|
|
||||||
|
A0A0R4I9D6_DANRE ZFIN» |
|
|
sympk | Symplekin (Symplekin isoform X1) |
Danio rerio TI:7955 None |
|
|
|
|||||
|
A0A1D8PQP8_CANAL EnsemblFungi» |
|
|
CAALFM_C700780WA orf19.7041 | RNA-processing protein |
Candida albicans TI:5476 None |
|
|
|
|||||
|
A0A1L8F3F9_XENLA Xenbase» |
|
|
sympk.S | Symplekin isoform X1 |
Xenopus laevis TI:8355 None |
|
|
||||||
|
A0A1Y1I3V9_KLENI EnsemblPlants» |
|
|
KFL_001760180 | HEAT repeat family protein |
Klebsormidium nitens TI:105231 None |
|
|
|
|||||
|
A0A2A6CSQ7_PRIPA EnsemblMetazoa» |
|
|
WBGene00276162 | Symk-1 |
Pristionchus pacificus TI:54126 None |
|
|
|
|||||
|
A0A2I2UYD9_FELCA Ensembl» |
|
|
SYMPK | Symplekin scaffold protein |
Felis catus TI:9685 None |
|
|
|
|||||
|
A0A2K3E241_CHLRE EnsemblPlants» |
|
|
CHLRE_02g099200v5 | Symplekin |
Chlamydomonas reinhardtii TI:3055 None |
|
|
|
|||||
|
A0A5F8HEV0_MONDO Ensembl» |
|
|
SYMPK | Symplekin |
Monodelphis domestica TI:13616 None |
|
|
||||||
|
A0A6I8PL60_ORNAN Ensembl» |
|
|
SYMPK | Symplekin |
Ornithorhynchus anatinus TI:9258 None |
|
|
||||||
|
A0A7M7RE72_STRPU EnsemblMetazoa» |
|
|
Symplekin |
Strongylocentrotus purpuratus TI:7668 None |
|
|
|||||||
|
A0A8I3MTP9_CANLF Ensembl» |
|
|
SYMPK | Symplekin scaffold protein |
Canis lupus TI:9612 None |
|
|
||||||
|
A0A8J0QIY6_XENTR Xenbase» |
|
|
sympk | Symplekin |
Xenopus tropicalis TI:8364 None |
|
|
||||||
|
A0A9J7KYJ5_BRAFL CTD» |
|
|
LOC118413513 | Symplekin-like isoform X1 |
Branchiostoma floridae TI:7739 None |
|
|
||||||
|
A2DQ40_TRIV3 VEuPathDB» |
|
|
TVAG_494090 | Symplekin C-terminal domain-containing protein |
Trichomonas vaginalis TI:5722 None |
|
|
|
|||||
|
A7E8R3_SCLS1 EnsemblFungi» |
|
|
SS1G_01691 | Symplekin/Pta1 N-terminal domain-containing protein |
Sclerotinia sclerotiorum TI:5180 None |
|
|
|
|||||
|
A7RP74_NEMVE EnsemblMetazoa» |
|
|
NEMVEDRAFT_v1g33075 | Symplekin C-terminal domain-containing protein |
Nematostella vectensis TI:45351 None |
|
|
|
|||||
|
A7STE5_NEMVE EnsemblMetazoa» |
|
|
NEMVEDRAFT_v1g131016 | Symplekin/Pta1 N-terminal domain-containing protein |
Nematostella vectensis TI:45351 None |
|
|
|
|||||
|
A8WQK5_CAEBR WormBase» |
|
|
symk-1 | Protein CBR-SYMK-1 |
Caenorhabditis briggsae TI:6238 None |
|
|
|
|||||
|
A9URI3_MONBE EnsemblProtists» |
|
|
MONBRDRAFT_31365 | Symplekin |
Monosiga brevicollis TI:81824 None |
|
|
|
|||||
|
B3S0M3_TRIAD EnsemblMetazoa» |
|
|
TRIADDRAFT_57101 | Symplekin |
Trichoplax adhaerens TI:10228 None |
|
|
|
|||||
|
B6K1D9_SCHJY EnsemblFungi» |
|
|
SJAG_02865 | mRNA cleavage and polyadenylation specificity factor complex subunit Pta1 |
Schizosaccharomyces japonicus TI:4897 None |
|
|
|
|||||
|
B7QNR2_IXOSC EnsemblMetazoa» |
|
|
IscW_ISCW015151 | Symplekin, putative |
Ixodes scapularis TI:6945 None |
|
|
|
|||||
|
B8BYA6_THAPS EnsemblProtists» |
|
|
THAPSDRAFT_21839 | Symplekin C-terminal domain-containing protein |
Thalassiosira pseudonana TI:35128 None |
|
|
|
|||||
|
C8VMC6_EMENI EnsemblFungi» |
|
|
ANIA_01456 | mRNA cleavage and polyadenylation specificity factor complex subunit (Pta1), putative (AFU_orthologue AFUA_8G04420) |
Emericella nidulans TI:162425 None |
|
|
|
|||||
|
D6WKQ1_TRICA EnsemblMetazoa» |
|
|
AUGUSTUS-3.0.2_10414 | Symplekin-like Protein |
Tribolium castaneum TI:7070 None |
|
|
|
|||||
|
E1BJF6_BOVIN Ensembl» |
|
|
SYMPK | Symplekin scaffold protein |
Bos taurus TI:9913 None |
|
|
||||||
|
E9GTR9_DAPPU EnsemblMetazoa» |
|
|
DAPPUDRAFT_321741 | Symplekin |
Daphnia pulex TI:6669 None |
|
|
|
|||||
|
F0ZXP5_DICPU EnsemblProtists» |
|
|
DICPUDRAFT_89712 | Symplekin |
Dictyostelium purpureum TI:5786 None |
|
|
|
|||||
|
F1RM40_PIG Ensembl» |
|
|
SYMPK | Symplekin scaffold protein |
Sus scrofa TI:9823 None |
|
|
||||||
|
F4P940_BATDJ EnsemblBacteria» |
|
|
BATDEDRAFT_35753 | Symplekin |
Batrachochytrium dendrobatidis TI:109871 None |
|
|
|
|||||
|
G3QLK1_GORGO Ensembl» |
|
|
SYMPK | Symplekin |
Gorilla gorilla TI:9593 None |
|
|
|
|||||
|
H2MKJ4_ORYLA Ensembl» |
|
|
sympk | Symplekin |
Oryzias latipes TI:8090 None |
|
|
||||||
|
H2QGM1_PANTR Ensembl» |
|
|
SYMPK | Symplekin (Symplekin scaffold protein) |
Pan troglodytes TI:9598 None |
|
|
|
|||||
|
H2XWK5_CIOIN Ensembl» |
|
|
Symplekin |
Ciona intestinalis TI:7719 None |
|
|
|
||||||
|
H3GED7_PHYRM EnsemblProtists» |
|
|
Symplekin C-terminal domain-containing protein |
Phytophthora ramorum TI:164328 None |
|
|
|
||||||
|
H6QUB7_PUCGT EnsemblFungi» |
|
|
PGTG_22369 | Symplekin |
Puccinia graminis TI:5297 None |
|
|
|
|||||
|
H9G8S2_ANOCA Ensembl» |
|
|
Symplekin |
Anolis carolinensis TI:28377 None |
|
|
|||||||
|
I0FJW9_MACMU Ensembl» |
|
|
SYMPK | Symplekin (Symplekin scaffold protein) |
Macaca mulatta TI:9544 None |
|
|
|
|||||
|
O16929_CAEEL WormBase» |
|
|
symk-1 | DUF3453 domain-containing protein |
Caenorhabditis elegans TI:6239 None |
|
|
|
|||||
|
Q4Q626_LEIMA EnsemblProtists» |
|
|
LMJF_31_2350 | Symplekin C-terminal domain-containing protein |
Leishmania major TI:5664 None |
|
|
|
|||||
|
Q4WCH3_ASPFU EnsemblFungi» |
|
|
AFUA_8G04420 | mRNA cleavage and polyadenylation specificity factor complex subunit (Pta1), putative |
Aspergillus fumigatus TI:746128 None |
|
|
|
|||||
|
Q54PX4_DICDI dictyBase» |
|
|
sympk | Symplekin |
Dictyostelium discoideum TI:44689 None |
|
|
|
|||||
|
Q57V70_TRYB2 VEuPathDB» |
|
|
Tb08.30P3.10 | Symplekin C-terminal domain-containing protein |
Trypanosoma brucei TI:5691 None |
|
|
|
|||||
|
Q584L2_TRYB2 VEuPathDB» |
|
|
Tb04.3M17.180 | Symplekin C-terminal domain-containing protein |
Trypanosoma brucei TI:5691 None |
|
|
|
|||||
|
Q5KFF7_CRYNJ EnsemblFungi» |
|
|
CNF01910 | Cleavage/polyadenylation specificity factor, putative |
Cryptococcus neoformans TI:5207 None |
|
|
|
|||||
|
Q6C2Z4_YARLI EnsemblFungi» |
|
|
YALI0_F03883g | YALI0F03883p |
Yarrowia lipolytica TI:4952 None |
|
|
|
|||||
|
Q758Y5_ASHGO EnsemblFungi» |
|
|
AGOS_ADR392W | ADR392Wp |
Ashbya gossypii TI:33169 None |
|
|
|
|||||
|
Q7QCG6_ANOGA EnsemblMetazoa» |
|
|
1273349 | AGAP002618-PA |
Anopheles gambiae TI:7165 None |
|
|
|
|||||
|
SYMPK_XENLA Xenbase» |
|
|
sympk | Symplekin |
Xenopus laevis TI:8355 None |
|
|
|
|||||
|
T1F0X8_HELRO EnsemblMetazoa» |
|
|
20202478 | Symplekin/Pta1 N-terminal domain-containing protein |
Helobdella robusta TI:6412 None |
|
|
|
|||||
|
T1G9J0_HELRO EnsemblMetazoa» |
|
|
20217737 | Symplekin C-terminal domain-containing protein |
Helobdella robusta TI:6412 None |
|
|
|
|||||
|
V5IPN5_NEUCR EnsemblFungi» |
|
|
NCU09128 | Symplekin/Pta1 N-terminal domain-containing protein |
Neurospora crassa TI:5141 None |
|
|
|
|||||
|
W5NA60_LEPOC Ensembl» |
|
|
Uncharacterized protein |
Lepisosteus oculatus TI:7918 None |
|
|
|
||||||
|
W5NA63_LEPOC Ensembl» |
|
|
Clathrin/coatomer adaptor adaptin-like N-terminal domain-containing protein |
Lepisosteus oculatus TI:7918 None |
|
|
|
||||||
