Collated Gene Ontology terms

Biological process: RNA binding(2013, 2025)

Molecular function: mRNA processing2025 cell adhesion2025 mRNA 3'-end processing2025 termination of RNA polymerase II transcription, poly(A)-coupled2019, 2025 tRNA processing2005, 2013, 2025 nuclear histone mRNA catabolic process2024, 2025 negative regulation of protein binding2018 co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway2023, 2024 response to xenobiotic stimulus2014 mRNA trans splicing, via spliceosome2016
mRNA 3'-end processing by stem-loop binding and cleavage2016

Cellular component: mRNA cleavage and polyadenylation specificity factor complex2004, 2016, 2017, 2019, 2020, 2025 nucleus2009, 2017, 2025 nucleoplasm2016, 2017, 2025 plasma membrane2025 nuclear body2017, 2025 nuclear stress granule2016, 2025 cytoskeleton2025 bicellular tight junction2025 cytoplasm2001, 2025 anchoring junction2025
tricellular tight junction2016 histone locus body2025 cytosol2025

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 15/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 3/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 2/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
PTA1_YEAST
SGD»
3.2
PTA1 Pre-tRNA-processing protein PTA1 Saccharomyces cerevisiae
TI:4932 None
 
SYMPK_DROME
FlyBase»
2.2
Sym Symplekin Drosophila melanogaster
TI:7227 None
 
SYMPK_HUMAN
Ensembl»
2.2
SYMPK Symplekin Homo sapiens
TI:9606 None
 
PTA1_SCHPO
PomBase»
2.1
pta1 mRNA cleavage and polyadenylation
specificity factor complex subunit pta1		 Schizosaccharomyces pombe
TI:4896 None
 
SYMPK_MOUSE
Ensembl»
1.0
Sympk Symplekin Mus musculus
TI:10090 None
 
A0A0R4I9D6_DANRE
ZFIN»
0.0
sympk Symplekin Danio rerio
TI:7955 None
 
F1LSH0_RAT
RGD»
0.0
Sympk Symplekin Rattus norvegicus
TI:10116 None
   
O16929_CAEEL
WormBase»
0.0
symk-1 DUF3453 domain-containing protein Caenorhabditis elegans
TI:6239 None
 
Q54PX4_DICDI
dictyBase»
0.0
sympk Symplekin Dictyostelium discoideum
TI:44689 None