Collated Gene Ontology terms

Biological process: identical protein binding(2025) hyaluronan synthase activity(2013)

Molecular function: protein secretion2011, 2019, 2025 protein import into nucleus2016, 2019 positive regulation of hyaluranon cable assembly2012 positive regulation of DNA-templated transcription2012 polysaccharide biosynthetic process2013 hyaluronan biosynthetic process2024 extracellular matrix assembly2013 double-strand break repair via nonhomologous end joining2025 Golgi organization2006

Cellular component: cytoplasm2013, 2019, 2025 nucleus2009, 2013, 2025 Golgi apparatus2006, 2024, 2025 membrane2025 cytosol2006, 2009 plasma membrane2022 hyaluranon cable2012 UDP-N-acetylglucosamine transferase complex2024

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 1/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 3/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
A0A1S4GXC6_ANOGA
EnsemblMetazoa»
0.0
Uncharacterized protein Anopheles gambiae
TI:7165 None
 
A0A7M7N4U0_STRPU
EnsemblMetazoa»
0.0
Transport and Golgi
organization protein 6 homolog		 Strongylocentrotus purpuratus
TI:7668 None
   
A0A9L0SK53_HORSE
Ensembl»
0.0
Transport and golgi organization 6 homolog Equus caballus
TI:9796 None 		     
F7A9P4_CIOIN
Ensembl»
0.0
DNA-dependent protein kinase catalytic
subunit CC3 domain-containing protein		 Ciona intestinalis
TI:7719 None
 
H2XVW9_CIOIN
Ensembl»
0.0
TANGO6 N-terminal domain-containing protein Ciona intestinalis
TI:7719 None 		     
H2Y3U5_CIOIN
Ensembl»
0.0
Condensin complex subunit
1 C-terminal domain-containing protein		 Ciona intestinalis
TI:7719 None 		     
H3GK10_PHYRM
EnsemblProtists»
0.0
Uncharacterized protein Phytophthora ramorum
TI:164328 None
 
W5M350_LEPOC
Ensembl»
0.0
Transport and golgi organization 6 homolog Lepisosteus oculatus
TI:7918 None
 
T1EGX0_HELRO
EnsemblMetazoa»
0.0
20195820 Uncharacterized protein Helobdella robusta
TI:6412 None 		 
 
T1FG16_HELRO
EnsemblMetazoa»
0.0
20207765 TANGO6 N-terminal domain-containing protein Helobdella robusta
TI:6412 None 		 
 
Q4WMC8_ASPFU
TubercuList»
0.0
AFUA_6G10360 Protein required for cell viability, putative Aspergillus fumigatus
TI:746128 None
 
Q755H0_EREGS
euHCVdb»
0.0
AGOS_AFL147C AFL147Cp Eremothecium gossypii
TI:33169 None
 
Q5BAH4_EMENI
TubercuList»
0.0
ANIA_02456 Protein required for cell
viability, putative (AFU_orthologue AFUA_6G10360)		 Emericella nidulans
TI:162425 None
 
D6WL57_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_14300 Transmembrane and coiled-coil
domain-containing protein 7		 Tribolium castaneum
TI:7070 None
 
F4P9L1_BATDJ
neXtProt»
0.0
BATDEDRAFT_26940 RNA polymerase II assembly
factor Rtp1 C-terminal domain-containing protein		 Batrachochytrium dendrobatidis
TI:109871 None
 
A0A1D8PRI9_CANAL
CGD»
0.0
CAALFM_C704150WA orf19.7159 RNA polymerase II assembly
factor Rtp1 C-terminal domain-containing protein		 Candida albicans
TI:5476 None
 
Q5KQ11_CRYD1
TubercuList»
0.0
CNA00860 RNA polymerase II assembly
factor Rtp1 C-terminal domain-containing protein		 Cryptococcus deneoformans
TI:40410 None
 
E9GD13_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_302379 Uncharacterized protein Daphnia pulex
TI:6669 None
 
Q54Y12_DICDI
dictyBase»
0.0
DDB_G0278691 Uncharacterized protein Dictyostelium discoideum
TI:44689 None 		 
 
Q54Y11_DICDI
dictyBase»
0.0
DDB_G0278693 Uncharacterized protein Dictyostelium discoideum
TI:44689 None 		 
 
F0ZY84_DICPU
TubercuList»
0.0
DICPUDRAFT_5706 Uncharacterized protein Dictyostelium purpureum
TI:5786 None 		 
 
F0ZY85_DICPU
TubercuList»
0.0
DICPUDRAFT_95597 Uncharacterized protein Dictyostelium purpureum
TI:5786 None 		 
 
A0A0G2JYH9_RAT
RGD»
3.5
Has3 Transport and golgi organization 6 homolog Rattus norvegicus
TI:10116 None
   
B7QM98_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW014758 RNA polymerase II assembly
factor Rtp1 C-terminal domain-containing protein		 Ixodes scapularis
TI:6945 None 		 
 
B7QM99_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW014759 TANGO6 N-terminal domain-containing protein Ixodes scapularis
TI:6945 None 		 
 
A0A7U2F6Y6_PHANO
TubercuList»
0.0
JI435_066880 RNA polymerase II assembly
factor Rtp1 C-terminal domain-containing protein		 Phaeosphaeria nodorum
TI:13684 None 		 
 
A9RTL0_PHYPA
EnsemblPlants»
0.0
LOC112274198 Uncharacterized protein Physcomitrium patens
TI:3218 None
 
A0A9J7L474_BRAFL
neXtProt»
0.0
LOC118414754 Transport and Golgi
organization protein 6 homolog		 Branchiostoma floridae
TI:7739 None
   
A0A2R6WXF0_MARPO
euHCVdb»
0.0
MARPO_0050s0007 TANGO6 HEAT repeat domain-containing protein Marchantia polymorpha
TI:3197 None
 
Q7RU49_NEUCR
TubercuList»
0.0
NCU01615 Protein required for cell viability Neurospora crassa
TI:5141 None
 
A7S0G2_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g99870 Transport and Golgi
organization protein 6 homolog		 Nematostella vectensis
TI:45351 None
 
A7S0G0_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g99899 RNA polymerase II assembly
factor Rtp1 C-terminal domain-containing protein		 Nematostella vectensis
TI:45351 None 		 
 
E3KFM6_PUCGT
TubercuList»
0.0
PGTG_09043 RNA polymerase II assembly
factor Rtp1 C-terminal domain-containing protein		 Puccinia graminis
TI:5297 None
 
RTP1_YEAST
SGD»
1.3
RTP1 RNA polymerase II assembly factor RTP1 (Required for nuclear transport of
RNA pol II protein 1) (Transport and Golgi organization protein 6 homolog)		 Saccharomyces cerevisiae
TI:4932 None
 
D8S0C6_SELML
euHCVdb»
0.0
SELMODRAFT_416765 TANGO6 HEAT repeat domain-containing protein Selaginella moellendorffii
TI:88036 None
 
D8SB13_SELML
euHCVdb»
0.0
SELMODRAFT_420121 Uncharacterized protein Selaginella moellendorffii
TI:88036 None
 
A7F708_SCLS1
TubercuList»
0.0
SS1G_13388 RNA polymerase II assembly
factor Rtp1 C-terminal domain-containing protein		 Sclerotinia sclerotiorum
TI:5180 None
 
A0A1D5RHR5_MACMU
Ensembl»
0.0
TANGO6 Transport and golgi organization 6 homolog Macaca mulatta
TI:9544 None
   
A0A287BPU8_PIG
Ensembl»
0.0
TANGO6 Transport and golgi organization 6 homolog Sus scrofa
TI:9823 None
   
A0A5F8GJE4_MONDO
Ensembl»
0.0
TANGO6 Transport and golgi organization 6 homolog Monodelphis domestica
TI:13616 None
   
A0A8I3RVT9_CANLF
Ensembl»
0.0
TANGO6 Transport and golgi organization 6 homolog Canis lupus
TI:9612 None
   
F1MNM6_BOVIN
Ensembl»
0.0
TANGO6 Transport and golgi organization 6 homolog Bos taurus
TI:9913 None
   
F6TMC8_ORNAN
Ensembl»
0.0
TANGO6 Transport and golgi organization 6 homolog Ornithorhynchus anatinus
TI:9258 None
   
G3R3G9_GORGO
Ensembl»
0.0
TANGO6 Transport and golgi organization 6 homolog Gorilla gorilla
TI:9593 None
 
H2MIW5_ORYLA
Ensembl»
0.0
TANGO6 Transport and golgi organization 6 homolog Oryzias latipes
TI:8090 None
   
H2RA28_PANTR
Ensembl»
0.0
TANGO6 Transport and golgi organization 6 homolog Pan troglodytes
TI:9598 None
 
H9G717_ANOCA
Ensembl»
0.0
TANGO6 Transport and golgi organization 6 homolog Anolis carolinensis
TI:28377 None
   
TNG6_HUMAN
Ensembl»
0.5
TANGO6 Transport and Golgi organization protein 6
homolog (Transmembrane and coiled-coil domain-containing protein 7)		 Homo sapiens
TI:9606 None
 
B8CDN7_THAPS
neXtProt»
0.0
THAPSDRAFT_25065 RNA polymerase II assembly
factor Rtp1 C-terminal domain-containing protein		 Thalassiosira pseudonana
TI:35128 None
 
A0A8V0XW65_CHICK
Ensembl»
0.5
TMCO7 Transport and golgi organization 6 homolog Gallus gallus
TI:9031 None
   
B3RIP3_TRIAD
CTD»
0.0
TRIADDRAFT_52476 Uncharacterized protein Trichoplax adhaerens
TI:10228 None 		 
 
B3RIP4_TRIAD
CTD»
0.0
TRIADDRAFT_52477 TANGO6 N-terminal domain-containing protein Trichoplax adhaerens
TI:10228 None 		 
 
A2D8B0_TRIV3
TubercuList»
0.0
TVAG_072060 RNA polymerase II assembly
factor Rtp1 C-terminal domain-containing protein		 Trichomonas vaginalis
TI:5722 None
 
TNG6_DROME
FlyBase»
2.1
Tango6 Transport and Golgi organization protein 6 Drosophila melanogaster
TI:7227 None
 
TNG6_MOUSE
Ensembl»
0.5
Tango6 Transport and Golgi organization protein 6
homolog (Transmembrane and coiled-coil domain-containing protein 7)		 Mus musculus
TI:10090 None
 
Q6CCN6_YARLI
TubercuList»
0.0
YALI0_C07909g YALI0C07909p Yarrowia lipolytica
TI:4952 None
 
A8X9X3_CAEBR
WormBase»
0.0
ekl-6 Protein CBG09896 Caenorhabditis briggsae
TI:6238 None
 
Q22528_CAEEL
WormBase»
0.5
ekl-6 RTP1_C1 domain-containing protein Caenorhabditis elegans
TI:6239 None
 
B6K0D5_SCHJY
TubercuList»
0.0
rtp1 Eukaryotic protein Schizosaccharomyces japonicus
TI:4897 None
 
RTP1_SCHPO
PomBase»
1.0
rtp1 RNA polymerase II assembly factor rtp1 Schizosaccharomyces pombe
TI:4896 None
 
F6QBJ5_XENTR
Xenbase»
0.0
tango6 Transport and Golgi organization protein 6
homolog (Transport and golgi organization 6 homolog)		 Xenopus tropicalis
TI:8364 None
   
A0A1L8GKZ4_XENLA
Xenbase»
0.0
tango6.L Transport and Golgi
organization protein 6 homolog		 Xenopus laevis
TI:8355 None