Collated Gene Ontology terms

Biological process: inositol-polyphosphate 5-phosphatase activity(2001, 2006, 2014, 2019, 2020, 2024) hydrolase activity(2024) inositol-1,4,5-trisphosphate 5-phosphatase activity(2024) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(2024) PH domain binding(2009, 2024) inositol phosphate phosphatase activity(2015, 2024) endonuclease activity(2024)

Molecular function: phosphatidylinositol dephosphorylation2014, 2024 negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway2023, 2024 organophosphate metabolic process2024 ovulation2004, 2024 negative regulation of epidermal growth factor receptor signaling pathway2023, 2024 intracellular signal transduction2014 inositol phosphate metabolic process2024

Cellular component: plasma membrane2011, 2020, 2024 dendrite2020, 2024 membrane2001, 2019, 2024 cell projection2024 nucleus2017

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 2/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
A0A803TBH3_ANOCA
Ensembl»
0.0
INPP5A inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Anolis carolinensis
TI:28377 None
   
Q7QEY1_ANOGA
EnsemblMetazoa»
0.0
1272061 inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Anopheles gambiae
TI:7165 None
 
A0A9J7KW82_BRAFL
CTD»
0.0
LOC118412784 inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Branchiostoma floridae
TI:7739 None
   
A8WZS2_CAEBR
WormBase»
0.0
CBG05397 CBG_05397 Protein CBG05397 Caenorhabditis briggsae
TI:6238 None
 
A8XKR4_CAEBR
WormBase»
0.0
ipp-5 inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Caenorhabditis briggsae
TI:6238 None
 
I5P1_CAEEL
WormBase»
3.1
ipp-5 Probable type I inositol
1,4,5-trisphosphate 5-phosphatase (5PTase) (EC 3.1.3.56)		 Caenorhabditis elegans
TI:6239 None
 
Q17543_CAEEL
WormBase»
0.5
C01B10.3 CELE_C01B10.3 Endonuclease/exonuclease/phosphatase
family protein		 Caenorhabditis elegans
TI:6239 None
 
A0A8I3PMF2_CANLF
Ensembl»
0.0
INPP5A inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Canis lupus
TI:9612 None
   
I5P1_CANLF
CTD»
0.0
INPP5A Inositol polyphosphate-5-phosphatase A (EC 3.1.3.56)
(Type I inositol 1,4,5-trisphosphate 5-phosphatase) (5PTase)		 Canis lupus
TI:9612 None
 
F6TVG3_CIOIN
Ensembl»
0.0
LOC100178482 Type I
inositol 1,4,5-trisphosphate 5-phosphatase-like		 Ciona intestinalis
TI:7719 None
   
A0A8M9PYV7_DANRE
CTD»
0.0
inpp5a inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Danio rerio
TI:7955 None
   
A0A8M9QG68_DANRE
CTD»
0.0
LOC101884438 inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Danio rerio
TI:7955 None
   
Q2YDR0_DANRE
ZFIN»
0.5
inpp5l inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Danio rerio
TI:7955 None
 
B7Z0Q2_DROME
FlyBase»
1.3
5PtaseI inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Drosophila melanogaster
TI:7227 None
 
A0A3Q2HVQ3_HORSE
Ensembl»
0.0
INPP5A inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Equus caballus
TI:9796 None
   
M3WE58_FELCA
Ensembl»
0.0
INPP5A inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Felis catus
TI:9685 None
 
A0A1D5PX66_CHICK
Ensembl»
0.5
INPP5A inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Gallus gallus
TI:9031 None
   
A0A2I2YQG2_GORGO
Ensembl»
0.0
INPP5A inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Gorilla gorilla
TI:9593 None
 
T1FZ48_HELRO
EnsemblMetazoa»
0.0
20214096 inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Helobdella robusta
TI:6412 None
 
I5P1_HUMAN
Ensembl»
5.0
INPP5A Inositol polyphosphate-5-phosphatase A (EC 3.1.3.56) (43 kDa inositol
polyphosphate 5-phosphatase) (Type I inositol 1,4,5-trisphosphate 5-phosphatase) (5PTase)		 Homo sapiens
TI:9606 None
 
B7PLK8_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW018836 Type I inositol-1,4,5-trisphosphate 5-phosphatase, putative
(Type I inositol-1,4,5-trisphosphate 5-phosphatase, putative (Fragment))		 Ixodes scapularis
TI:6945 None
 
B7PLK9_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW018837 inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Ixodes scapularis
TI:6945 None
 
Q4QGX8_LEIMA
EnsemblProtists»
0.0
LMJF_11_1010 Putative inositol-1,4,5-trisphosphate (IP3)
5-phosphatase (EC 3.1.3.56)		 Leishmania major
TI:5664 None
 
W5MKU3_LEPOC
Ensembl»
0.0
INPP5A inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Lepisosteus oculatus
TI:7918 None
 
W5ND01_LEPOC
Ensembl»
0.0
inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Lepisosteus oculatus
TI:7918 None
 
H9FU21_MACMU
Ensembl»
0.0
INPP5A inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Macaca mulatta
TI:9544 None
 
A9V458_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_33207 inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Monosiga brevicollis
TI:81824 None
 
I5P1_MOUSE
Ensembl»
2.1
Inpp5a Inositol polyphosphate-5-phosphatase A (EC 3.1.3.56)
(Type I inositol 1,4,5-trisphosphate 5-phosphatase) (5PTase)		 Mus musculus
TI:10090 None
 
A7RGY0_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g196982 inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Nematostella vectensis
TI:45351 None
 
A0A6I8PR23_ORNAN
Ensembl»
0.0
INPP5A inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Ornithorhynchus anatinus
TI:9258 None
   
H2L4H6_ORYLA
Ensembl»
0.0
INPP5A inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Oryzias latipes
TI:8090 None
   
H2M7F8_ORYLA
Ensembl»
0.0
LOC101171587 inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Oryzias latipes
TI:8090 None
   
A0A2I3TRE1_PANTR
Ensembl»
0.0
INPP5A inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Pan troglodytes
TI:9598 None
 
A0A2A6BXG5_PRIPA
EnsemblMetazoa»
0.0
WBGene00091024 Endonuclease/exonuclease/phosphatase
domain-containing protein		 Pristionchus pacificus
TI:54126 None
 
A0A2A6CU51_PRIPA
EnsemblMetazoa»
0.0
WBGene00099139 inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Pristionchus pacificus
TI:54126 None
 
I5P1_RAT
RGD»
3.3
Inpp5a Inositol polyphosphate-5-phosphatase A (EC 3.1.3.56)
(Type I inositol 1,4,5-trisphosphate 5-phosphatase) (5PTase)		 Rattus norvegicus
TI:10116 None
 
A0A7M7NZT8_STRPU
EnsemblMetazoa»
0.0
inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Strongylocentrotus purpuratus
TI:7668 None
   
F1SDI6_PIG
Ensembl»
0.0
INPP5A inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Sus scrofa
TI:9823 None
   
D6X3B1_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_11918 inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Tribolium castaneum
TI:7070 None
 
B3S8V9_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_31282 inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Trichoplax adhaerens
TI:10228 None
 
Q385E2_TRYB2
VEuPathDB»
0.0
Tb11.02.4140 inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Trypanosoma brucei
TI:5691 None
 
A0A1L8H274_XENLA
Xenbase»
0.0
inpp5a.2.L inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Xenopus laevis
TI:8355 None
   
A0A8J1JSR3_XENTR
Xenbase»
0.0
inpp5a.1 inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Xenopus tropicalis
TI:8364 None
   
A0A8J1LA99_XENLA
Xenbase»
0.0
inpp5a.1.S inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Xenopus laevis
TI:8355 None
   
A0A8J1LC11_XENLA
Xenbase»
0.0
inpp5a.1.L inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Xenopus laevis
TI:8355 None
   
F6ZFS5_XENTR
Xenbase»
0.0
inpp5a.2 inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Xenopus tropicalis
TI:8364 None