Collated Gene Ontology terms

Biological process: inositol-polyphosphate 5-phosphatase activity(2001, 2006, 2014, 2019, 2020, 2024) hydrolase activity(2024) inositol-1,4,5-trisphosphate 5-phosphatase activity(2024) inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity(2024) PH domain binding(2009, 2024) inositol phosphate phosphatase activity(2015, 2024) endonuclease activity(2024)

Molecular function: phosphatidylinositol dephosphorylation2014, 2024 negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway2023, 2024 organophosphate metabolic process2024 ovulation2004, 2024 negative regulation of epidermal growth factor receptor signaling pathway2023, 2024 intracellular signal transduction2014 inositol phosphate metabolic process2024

Cellular component: plasma membrane2011, 2020, 2024 dendrite2020, 2024 membrane2001, 2019, 2024 cell projection2024 nucleus2017

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 2/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
I5P1_HUMAN
Ensembl»
5.0
INPP5A Inositol polyphosphate-5-phosphatase A (EC 3.1.3.56) (43 kDa inositol
polyphosphate 5-phosphatase) (Type I inositol 1,4,5-trisphosphate 5-phosphatase) (5PTase)		 Homo sapiens
TI:9606 None
 
I5P1_RAT
RGD»
3.3
Inpp5a Inositol polyphosphate-5-phosphatase A (EC 3.1.3.56)
(Type I inositol 1,4,5-trisphosphate 5-phosphatase) (5PTase)		 Rattus norvegicus
TI:10116 None
 
I5P1_CAEEL
WormBase»
3.1
ipp-5 Probable type I inositol
1,4,5-trisphosphate 5-phosphatase (5PTase) (EC 3.1.3.56)		 Caenorhabditis elegans
TI:6239 None
 
I5P1_MOUSE
Ensembl»
2.1
Inpp5a Inositol polyphosphate-5-phosphatase A (EC 3.1.3.56)
(Type I inositol 1,4,5-trisphosphate 5-phosphatase) (5PTase)		 Mus musculus
TI:10090 None
 
B7Z0Q2_DROME
FlyBase»
1.3
5PtaseI inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Drosophila melanogaster
TI:7227 None
 
A0A1D5PX66_CHICK
Ensembl»
0.5
INPP5A inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Gallus gallus
TI:9031 None
   
Q17543_CAEEL
WormBase»
0.5
C01B10.3 CELE_C01B10.3 Endonuclease/exonuclease/phosphatase
family protein		 Caenorhabditis elegans
TI:6239 None
 
Q2YDR0_DANRE
ZFIN»
0.5
inpp5l inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Danio rerio
TI:7955 None
 
A0A8M9PYV7_DANRE
CTD»
0.0
inpp5a inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Danio rerio
TI:7955 None
   
A0A8M9QG68_DANRE
CTD»
0.0
LOC101884438 inositol-polyphosphate 5-phosphatase
(EC 3.1.3.56)		 Danio rerio
TI:7955 None