Collated Gene Ontology terms

Biological process: serine-type endopeptidase inhibitor activity(2017, 2025) peptidase inhibitor activity(2025) ion channel inhibitor activity(2025) enzyme inhibitor activity(2025)

Molecular function: negative regulation of flagellated sperm motility2015, 2024, 2025 defense response to bacterium2012, 2025 negative regulation of calcium ion import2015, 2025 negative regulation of peptidase activity2012 venom-mediated perturbation of hemostasis2025 insemination2025 innate immune response2020 antibacterial humoral response2020

Cellular component: extracellular space2012, 2015, 2017, 2018, 2020, 2025 extracellular region2025 cell surface2015, 2025 protein-containing complex2015, 2025 cytoplasm2003, 2025 acrosomal vesicle2011, 2025 sperm plasma membrane2016 nematocyst2025

Phylogenetic distribution

Chordates: 15/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 0/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 2/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
Q4V621_DROME
FlyBase»
0.5
Acp24A4 ACP24A4 (Accessory gland protein 24A4, isoform B) (Accessory
gland protein 24A4, isoform C) (GEO10734p1) (IP06005p) (IP06105p)		 Drosophila melanogaster
TI:7227 None
 
EPPI_HUMAN
Ensembl»
3.7
EPPIN Eppin (Cancer/testis antigen 71) (CT71) (Epididymal protease inhibitor) (Protease inhibitor WAP7) (Serine protease
inhibitor-like with Kunitz and WAP domains 1) (WAP four-disulfide core domain protein 7)		 Homo sapiens
TI:9606 None
 
EPPI_MOUSE
Ensembl»
1.5
Eppin Eppin (Epididymal protease inhibitor) (Serine protease
inhibitor-like with Kunitz and WAP domains 1)		 Mus musculus
TI:10090 None
 
WFC6A_MOUSE
Ensembl»
0.5
Wfdc6a WAP four-disulfide core domain protein
6A (Putative protease inhibitor WAP6A)		 Mus musculus
TI:10090 None
 
Q9VQT7_DROME
FlyBase»
0.0
Dmel\CG16713 RH15675p (RH15676p) Drosophila melanogaster
TI:7227 None
 
WFC6B_MOUSE
Ensembl»
0.5
Wfdc6b WAP four-disulfide core domain protein
6B (Putative protease inhibitor WAP6B)		 Mus musculus
TI:10090 None
 
EPPI_RAT
RGD»
3.5
Eppin Eppin (Epididymal protease inhibitor) (Serine protease
inhibitor-like with Kunitz and WAP domains 1)		 Rattus norvegicus
TI:10116 None
 
E1JHS4_DROME
FlyBase»
0.0
Dmel\CG42464 BPTI/Kunitz inhibitor domain-containing protein Drosophila melanogaster
TI:7227 None
 
O16701_CAEEL
WormBase»
0.5
CELE_R12A1.3 R12A1.3 Kunitz/Bovine pancreatic trypsin
inhibitor domain protein		 Caenorhabditis elegans
TI:6239 None
 
Q6IE19_RAT
RGD»
0.5
Wfdc6b WAP four-disulfide core 6-like 1
(WAP four-disulfide core domain 6B)		 Rattus norvegicus
TI:10116 None