Collated Gene Ontology terms

Biological process: serine-type endopeptidase inhibitor activity(2017, 2025) peptidase inhibitor activity(2025) ion channel inhibitor activity(2025) enzyme inhibitor activity(2025)

Molecular function: negative regulation of flagellated sperm motility2015, 2024, 2025 defense response to bacterium2012, 2025 negative regulation of calcium ion import2015, 2025 negative regulation of peptidase activity2012 venom-mediated perturbation of hemostasis2025 insemination2025 innate immune response2020 antibacterial humoral response2020

Cellular component: extracellular space2012, 2015, 2017, 2018, 2020, 2025 extracellular region2025 cell surface2015, 2025 protein-containing complex2015, 2025 cytoplasm2003, 2025 acrosomal vesicle2011, 2025 sperm plasma membrane2016 nematocyst2025

Phylogenetic distribution

Chordates: 15/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 0/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 2/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
A0A287AZ32_PIG
Ensembl»
0.0
Uncharacterized protein Sus scrofa
TI:9823 None
   
A0A287BQB3_PIG
Ensembl»
0.0
EPPIN Epididymal peptidase inhibitor Sus scrofa
TI:9823 None
   
A0A2A6BRW8_PRIPA
EnsemblMetazoa»
0.0
WBGene00106535 BPTI/Kunitz inhibitor domain-containing protein Pristionchus pacificus
TI:54126 None
   
A0A2I2YQ06_GORGO
Ensembl»
0.0
BPTI/Kunitz inhibitor domain-containing protein Gorilla gorilla
TI:9593 None
 
A0A2I3SFC6_PANTR
Ensembl»
0.0
WFDC6 BPTI/Kunitz inhibitor domain-containing protein Pan troglodytes
TI:9598 None
 
A0A3Q1M4H9_BOVIN
Ensembl»
0.0
BPTI/Kunitz inhibitor domain-containing protein Bos taurus
TI:9913 None
   
A0A3Q2L4H4_HORSE
Ensembl»
0.0
Eppin Equus caballus
TI:9796 None
   
A0A5F8GC46_MONDO
Ensembl»
0.0
BPTI/Kunitz inhibitor domain-containing protein Monodelphis domestica
TI:13616 None
   
A0A6I8MZH9_ORNAN
Ensembl»
0.0
BPTI/Kunitz inhibitor domain-containing protein Ornithorhynchus anatinus
TI:9258 None
   
A0A6I8NPJ2_ORNAN
Ensembl»
0.0
LOC100081773 BPTI/Kunitz inhibitor domain-containing protein Ornithorhynchus anatinus
TI:9258 None
   
A0A6I8PFE9_ORNAN
Ensembl»
0.0
LOC100081858 WAP four-disulfide core domain 8 Ornithorhynchus anatinus
TI:9258 None
   
A0A7M7LSQ4_STRPU
EnsemblMetazoa»
0.0
Uncharacterized protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A803SZ10_ANOCA
Ensembl»
0.0
BPTI/Kunitz inhibitor domain-containing protein Anolis carolinensis
TI:28377 None
   
A0A803TBG4_ANOCA
Ensembl»
0.0
BPTI/Kunitz inhibitor domain-containing protein Anolis carolinensis
TI:28377 None
   
A0A803TD86_ANOCA
Ensembl»
0.0
LOC103280499 Uncharacterized protein Anolis carolinensis
TI:28377 None
   
A0A803TK70_ANOCA
Ensembl»
0.0
LOC103281241 BPTI/Kunitz inhibitor domain-containing protein Anolis carolinensis
TI:28377 None
   
A0A803TQH4_ANOCA
Ensembl»
0.0
LOC103282277 BPTI/Kunitz inhibitor domain-containing protein Anolis carolinensis
TI:28377 None
   
A0A803TUL7_ANOCA
Ensembl»
0.0
WAP domain-containing protein Anolis carolinensis
TI:28377 None
   
A0A8I3NVX9_CANLF
Ensembl»
0.0
LOC119865675 BPTI/Kunitz inhibitor domain-containing protein Canis lupus
TI:9612 None
   
A0A9J7KUV9_BRAFL
euHCVdb»
0.0
LOC118411634 Papilin-like Branchiostoma floridae
TI:7739 None
   
A0ABI8A4N9_FELCA
Ensembl»
0.0
LOC101087913 Eppin-like Felis catus
TI:9685 None
   
A0ABI8A4Q8_FELCA
Ensembl»
0.0
WAP domain-containing protein Felis catus
TI:9685 None
   
A7S322_NEMVE
neXtProt»
0.0
NEMVEDRAFT_v1g102600 BPTI/Kunitz inhibitor domain-containing protein Nematostella vectensis
TI:45351 None
 
A8X268_CAEBR
WormBase»
0.0
CBG06419 CBG_06419 Protein CBG06419 Caenorhabditis briggsae
TI:6238 None
 
E1JHS4_DROME
FlyBase»
0.0
Dmel\CG42464 BPTI/Kunitz inhibitor domain-containing protein Drosophila melanogaster
TI:7227 None
 
E9HLG2_DAPPU
neXtProt»
0.0
DAPPUDRAFT_9483 BPTI/Kunitz inhibitor domain-containing protein Daphnia pulex
TI:6669 None
 
EPPI_HUMAN
Ensembl»
3.7
EPPIN Eppin (Cancer/testis antigen 71) (CT71) (Epididymal protease inhibitor) (Protease inhibitor WAP7) (Serine protease
inhibitor-like with Kunitz and WAP domains 1) (WAP four-disulfide core domain protein 7)		 Homo sapiens
TI:9606 None
 
EPPI_MACMU
CTD»
0.0
EPPIN Eppin (Epididymal protease inhibitor) (Serine protease
inhibitor-like with Kunitz and WAP domains 1)		 Macaca mulatta
TI:9544 None
 
EPPI_MOUSE
Ensembl»
1.5
Eppin Eppin (Epididymal protease inhibitor) (Serine protease
inhibitor-like with Kunitz and WAP domains 1)		 Mus musculus
TI:10090 None
 
EPPI_RAT
RGD»
3.5
Eppin Eppin (Epididymal protease inhibitor) (Serine protease
inhibitor-like with Kunitz and WAP domains 1)		 Rattus norvegicus
TI:10116 None
 
F7GKY8_MONDO
Ensembl»
0.0
BPTI/Kunitz inhibitor domain-containing protein Monodelphis domestica
TI:13616 None
   
F7HT91_MACMU
Ensembl»
0.0
WAP four-disulfide core domain 6 Macaca mulatta
TI:9544 None
   
F7HTA3_MACMU
Ensembl»
0.0
SPINLW1 Eppin (Epididymal protease inhibitor) (Serine protease
inhibitor-like with Kunitz and WAP domains 1)		 Macaca mulatta
TI:9544 None
   
G2HDV8_PANTR
Ensembl»
0.0
EPPIN Eppin (Epididymal protease inhibitor) (Serine protease
inhibitor-like with Kunitz and WAP domains 1)		 Pan troglodytes
TI:9598 None
 
G3RES3_GORGO
Ensembl»
0.0
EPPIN Eppin (Epididymal protease inhibitor) (Serine protease
inhibitor-like with Kunitz and WAP domains 1)		 Gorilla gorilla
TI:9593 None
 
O16701_CAEEL
WormBase»
0.5
CELE_R12A1.3 R12A1.3 Kunitz/Bovine pancreatic trypsin
inhibitor domain protein		 Caenorhabditis elegans
TI:6239 None
 
Q32KP8_BOVIN
Ensembl»
0.0
SPINLW1 Serine peptidase inhibitor-like, with Kunitz
and WAP domains 1 (Eppin)		 Bos taurus
TI:9913 None
 
Q4V621_DROME
FlyBase»
0.5
Acp24A4 ACP24A4 (Accessory gland protein 24A4, isoform B) (Accessory
gland protein 24A4, isoform C) (GEO10734p1) (IP06005p) (IP06105p)		 Drosophila melanogaster
TI:7227 None
 
Q6IE19_RAT
RGD»
0.5
Wfdc6b WAP four-disulfide core 6-like 1
(WAP four-disulfide core domain 6B)		 Rattus norvegicus
TI:10116 None
 
Q9VQT7_DROME
FlyBase»
0.0
Dmel\CG16713 RH15675p (RH15676p) Drosophila melanogaster
TI:7227 None
 
WFC6A_MOUSE
Ensembl»
0.5
Wfdc6a WAP four-disulfide core domain protein
6A (Putative protease inhibitor WAP6A)		 Mus musculus
TI:10090 None
 
WFC6B_MOUSE
Ensembl»
0.5
Wfdc6b WAP four-disulfide core domain protein
6B (Putative protease inhibitor WAP6B)		 Mus musculus
TI:10090 None