Collated Gene Ontology terms

Biological process: zinc ion binding(2025) methyl-CpG binding(2017) metal ion binding(2025) DNA binding(2025)

Molecular function: apoptotic process2010, 2019, 2025 cell projection organization2025 determination of left/right symmetry2016, 2017, 2024, 2025 cilium assembly2017, 2024, 2025 negative regulation of cilium assembly2015, 2025 negative regulation of cell growth2010, 2025 cilium movement2016, 2024 flagellated sperm motility2021, 2024 epithelial cilium movement involved in determination of left/right asymmetry2016, 2021 spermatogenesis2025
sperm flagellum assembly2024 manchette assembly2024 cell differentiation2025 protein localization to motile cilium2021 negative regulation of transcription by RNA polymerase II2025 cerebrospinal fluid circulation2021 axoneme assembly2025 DNA-templated transcription2025 DNA methylation-dependent constitutive heterochromatin formation2024

Cellular component: cilium2024, 2025 keratin filament2006, 2015, 2019, 2025 centrosome2011, 2024, 2025 axoneme2015, 2017, 2021, 2024, 2025 cytoskeleton2025 centriolar satellite2021, 2024, 2025 spindle pole2024, 2025 polymeric cytoskeletal fiber2025 mitochondrion2010, 2024, 2025 cytoplasm2010, 2025
plasma membrane2010, 2025 axonemal microtubule2022, 2023, 2025 ciliary transition zone2024, 2025 apical cortex2006, 2025 cytosol2024, 2025 sperm flagellum2024 intermediate filament2025 desmosome2015, 2025 manchette2024 extracellular region2025 ciliary transition fiber2015, 2025 axonemal A tubule inner sheath2024 ciliary base2015, 2025 sperm principal piece2025 sperm midpiece2025 nucleus2025 nucleoplasm2025 nuclear speck2025 nuclear membrane2025 nuclear matrix2025 ciliary basal body2025 chromosome2025 centriole2025 9+2 motile cilium2021 9+0 motile cilium2021

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 0/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 4/4 
Harosa: 3/4 
Hacrobia: 0/0 
Plants: 5/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
TCHP_MOUSE
Ensembl»
3.5
Tchp Trichoplein keratin filament-binding protein (Protein TCHP)
(Mitochondrial protein with oncostatic activity) (Mitostatin)		 Mus musculus
TI:10090 None
 
Q7K4X4_DROME
FlyBase»
0.5
Dmel\CG17230 GH24095p (Uncharacterized protein, isoform A) (Uncharacterized
protein, isoform B) (Uncharacterized protein, isoform C)		 Drosophila melanogaster
TI:7227 None
 
CFA53_DANRE
ZFIN»
4.5
cfap53 Cilia- and flagella-associated protein
53 (Coiled-coil domain-containing protein 11)		 Danio rerio
TI:7955 None
 
CFA53_HUMAN
Ensembl»
4.6
CFAP53 Cilia- and flagella-associated protein
53 (Coiled-coil domain-containing protein 11)		 Homo sapiens
TI:9606 None
 
G7N5F8_MACMU
Ensembl»
0.0
TCHP Trichoplein keratin filament-binding protein Macaca mulatta
TI:9544 None
 
TCHP_DANRE
ZFIN»
0.5
tchp Trichoplein keratin filament-binding
protein (Protein TCHP)		 Danio rerio
TI:7955 None
 
TCHP_HUMAN
Ensembl»
2.9
TCHP Trichoplein keratin filament-binding protein (Protein TCHP) (Mitochondrial
protein with oncostatic activity) (Mitostatin) (Tumor suppressor protein)		 Homo sapiens
TI:9606 None
 
W5N579_LEPOC
Ensembl»
0.0
Cilia- and flagella-associated protein 53 Lepisosteus oculatus
TI:7918 None
 
CFA53_MOUSE
Ensembl»
8.6
Cfap53 Cilia- and flagella-associated protein
53 (Coiled-coil domain-containing protein 11)		 Mus musculus
TI:10090 None
 
F1RIT5_PIG
Ensembl»
0.0
TCHP Trichoplein keratin filament-binding protein Sus scrofa
TI:9823 None
 
Q57VE0_TRYB2
TubercuList»
0.0
Tb05.30H13.190 Cilia- and flagella-associated protein 53 Trypanosoma brucei
TI:5691 None
 
TCHP_XENLA
Xenbase»
0.0
tchp Trichoplein keratin filament-binding
protein (Protein TCHP)		 Xenopus laevis
TI:8355 None
 
A0A1S4GZM9_ANOGA
EnsemblMetazoa»
0.0
Uncharacterized protein Anopheles gambiae
TI:7165 None
 
A0A1Y1HMU5_KLENI
euHCVdb»
0.0
KFL_000140290 Cilia- and flagella-associated protein 53 Klebsormidium nitens
TI:105231 None
 
A0A286ZZD2_PIG
Ensembl»
0.0
CFAP53 Cilia- and flagella-associated protein 53 Sus scrofa
TI:9823 None
 
A0A2K1K081_PHYPA
EnsemblPlants»
0.0
LOC112287828 Cilia- and flagella-associated protein 53 Physcomitrium patens
TI:3218 None
 
A0A2K3DY02_CHLRE
euHCVdb»
0.0
CHLRE_03g185050v5 Cilia- and flagella-associated protein 53 Chlamydomonas reinhardtii
TI:3055 None
 
A0A2R6XN31_MARPO
euHCVdb»
0.0
MARPO_0008s0187 Uncharacterized protein Marchantia polymorpha
TI:3197 None
 
A0C940_PARTE
euHCVdb»
0.0
GSPATT00006613001 Cilia- and flagella-associated protein 53 Paramecium tetraurelia
TI:5888 None
 
A0CS00_PARTE
euHCVdb»
0.0
GSPATT00038918001 Cilia- and flagella-associated protein 53 Paramecium tetraurelia
TI:5888 None
 
A0DG59_PARTE
neXtProt»
0.0
GSPATT00002154001 Cilia- and flagella-associated protein 53 Paramecium tetraurelia
TI:5888 None
 
A0DPS9_PARTE
euHCVdb»
0.0
GSPATT00019228001 Uncharacterized protein Paramecium tetraurelia
TI:5888 None
 
A0DPT0_PARTE
euHCVdb»
0.0
GSPATT00019229001 Uncharacterized protein Paramecium tetraurelia
TI:5888 None
 
A2G223_TRIV3
TubercuList»
0.0
TVAG_436250 Cilia- and flagella-associated protein 53 Trichomonas vaginalis
TI:5722 None
 
A2G2G6_TRIV3
TubercuList»
0.0
TVAG_023280 Cilia- and flagella-associated protein 53 Trichomonas vaginalis
TI:5722 None
 
A7RK95_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g198339 Trichoplein keratin filament-binding protein Nematostella vectensis
TI:45351 None
 
A7SJC8_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g120431 Cilia- and flagella-associated protein 53 Nematostella vectensis
TI:45351 None
 
A7SKB0_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g245840 Trichoplein keratin filament-binding protein Nematostella vectensis
TI:45351 None
 
A8BTT3_GIAIC
TubercuList»
0.0
GL50803_0016013 Cilia- and flagella-associated protein 53 Giardia intestinalis
TI:5741 None
 
A8JQT2_DROME
FlyBase»
0.0
CG12584 Trichohyalin Drosophila melanogaster
TI:7227 None
 
A9UQU7_MONBE
euHCVdb»
0.0
MONBRDRAFT_1351 Cilia- and flagella-associated protein 53 Monosiga brevicollis
TI:81824 None
 
A9URC2_MONBE
euHCVdb»
0.0
MONBRDRAFT_23153 Trichoplein keratin filament-binding protein Monosiga brevicollis
TI:81824 None
 
B1H1B8_XENTR
Xenbase»
0.0
cfap53 Cilia- and flagella-associated protein 53 Xenopus tropicalis
TI:8364 None
 
B3RSC4_TRIAD
CTD»
0.0
TRIADDRAFT_63249 Cilia- and flagella-associated protein 53 Trichoplax adhaerens
TI:10228 None
 
B3S4H7_TRIAD
CTD»
0.0
TRIADDRAFT_59089 Trichoplein keratin filament-binding protein Trichoplax adhaerens
TI:10228 None
 
B8BRA0_THAPS
euHCVdb»
0.0
THAPSDRAFT_1555 Trichohyalin-plectin-homology
domain-containing protein		 Thalassiosira pseudonana
TI:35128 None
 
C3XV29_BRAFL
euHCVdb»
0.0
LOC118426281 Trichoplein keratin filament-binding protein Branchiostoma floridae
TI:7739 None
 
CFA53_XENLA
Xenbase»
0.0
cfap53.L Cilia- and flagella-associated protein 53
(Coiled-coil domain-containing protein 11) (xCcdc11)		 Xenopus laevis
TI:8355 None
 
D2A6F1_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_14996 Trichoplein keratin filament-binding protein Tribolium castaneum
TI:7070 None
 
D6WS10_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_09525 Cilia- and flagella-associated protein 53 Tribolium castaneum
TI:7070 None
 
D8R1A6_SELML
euHCVdb»
0.0
SELMODRAFT_406736 Cilia- and flagella-associated protein 53 Selaginella moellendorffii
TI:88036 None
 
D8S1I0_SELML
euHCVdb»
0.0
SELMODRAFT_417142 Cilia- and flagella-associated protein 53 Selaginella moellendorffii
TI:88036 None
 
E9HIJ5_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_330101 Trichoplein keratin filament-binding protein Daphnia pulex
TI:6669 None
 
F5HMW6_ANOGA
EnsemblMetazoa»
0.0
11175707 A-kinase anchoring
protein AKAP120 (AGAP013011-PA)		 Anopheles gambiae
TI:7165 None
 
F6W1E1_CIOIN
Ensembl»
0.0
LOC100181281 Cilia- and flagella-associated protein 53 Ciona intestinalis
TI:7719 None
 
G3SGY6_GORGO
Ensembl»
0.0
TCHP Trichoplein keratin filament-binding protein Gorilla gorilla
TI:9593 None
 
H2Q6V0_PANTR
Ensembl»
0.0
TCHP Trichoplein keratin filament-binding protein Pan troglodytes
TI:9598 None
 
H2QEI8_PANTR
Ensembl»
0.0
CFAP53 Cilia- and flagella-associated protein 53 Pan troglodytes
TI:9598 None
 
H2Y326_CIOIN
Ensembl»
0.0
Trichoplein keratin filament-binding protein Ciona intestinalis
TI:7719 None
 
H3GEQ8_PHYRM
EnsemblProtists»
0.0
Cilia- and flagella-associated protein 53 Phytophthora ramorum
TI:164328 None
 
Q4QAZ3_LEIMA
TubercuList»
0.0
LMJF_23_1450 Cilia- and flagella-associated protein 53 Leishmania major
TI:5664 None
 
W5M9J4_LEPOC
Ensembl»
0.0
Trichoplein keratin filament-binding protein Lepisosteus oculatus
TI:7918 None
 
A0A3B3HVN3_ORYLA
Ensembl»
0.0
cfap53 Cilia- and flagella-associated protein 53 Oryzias latipes
TI:8090 None
   
A0A7M7P8X5_STRPU
EnsemblMetazoa»
0.0
Trichoplein keratin filament-binding protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7RHS4_STRPU
EnsemblMetazoa»
0.0
Cilia- and flagella-associated protein 53 Strongylocentrotus purpuratus
TI:7668 None
   
A0A8I3NV08_CANLF
Ensembl»
0.0
CFAP53 Cilia- and flagella-associated protein 53 Canis lupus
TI:9612 None
   
A0A8I3S567_CANLF
Ensembl»
0.0
TCHP Trichoplein keratin filament-binding protein Canis lupus
TI:9612 None
   
A0A8J1IQ99_XENTR
Xenbase»
0.0
tchp Trichoplein keratin filament-binding protein Xenopus tropicalis
TI:8364 None
   
A0A8J1LIY3_XENLA
CTD»
0.0
tchp.L Trichoplein keratin filament-binding protein Xenopus laevis
TI:8355 None
   
A0A8V0ZM89_CHICK
Ensembl»
0.5
TCHP Trichoplein keratin filament-binding protein Gallus gallus
TI:9031 None
   
A0A9J7MGH9_BRAFL
euHCVdb»
0.0
LOC118409764 Cilia- and flagella-associated protein 53 Branchiostoma floridae
TI:7739 None
   
A0A9L0R6K2_HORSE
Ensembl»
0.0
Trichoplein keratin filament-binding protein Equus caballus
TI:9796 None
   
A0ABI7Y6K2_FELCA
Ensembl»
0.0
TCHP Trichoplein keratin filament-binding protein Felis catus
TI:9685 None
   
CFA53_BOVIN
CTD»
0.0
CFAP53 Cilia- and flagella-associated protein 53 Bos taurus
TI:9913 None
   
D3ZY42_RAT
RGD»
2.0
Tchp Trichoplein keratin filament-binding protein Rattus norvegicus
TI:10116 None
   
F1MYY5_BOVIN
Ensembl»
0.0
TCHP Trichoplein keratin filament-binding protein Bos taurus
TI:9913 None
   
F6SVU9_MONDO
Ensembl»
0.0
TCHP Trichoplein keratin filament-binding protein Monodelphis domestica
TI:13616 None
   
F7AAE6_MONDO
Ensembl»
0.0
CFAP53 Cilia- and flagella-associated protein 53 Monodelphis domestica
TI:13616 None
   
F7BMH9_ORNAN
Ensembl»
0.0
TCHP Trichoplein keratin filament-binding protein Ornithorhynchus anatinus
TI:9258 None
   
F7F411_ORNAN
Ensembl»
0.0
CFAP53 Cilia- and flagella-associated protein 53 Ornithorhynchus anatinus
TI:9258 None
   
F7FBN7_MACMU
Ensembl»
0.0
MBD1 Cilia- and flagella-associated protein 53 (Methyl-CpG-binding
domain protein 1) (Methyl-CpG-binding protein MBD1)		 Macaca mulatta
TI:9544 None
   
H2LSW8_ORYLA
Ensembl»
0.0
tchp Trichoplein keratin filament-binding protein Oryzias latipes
TI:8090 None
   
H9GFW9_ANOCA
Ensembl»
0.0
cfap53 Cilia- and flagella-associated protein 53 Anolis carolinensis
TI:28377 None