Cluster UKP08988
- INTEGRATOR COMPLEX SUBUNIT 2
Standard knownness: 4.2; Custom knownness: None; Num. species: 43; Orthology database: Panther19.0; Protein members: 52
Collated Gene Ontology terms
Molecular function: snRNA 3'-end processing2012, 2017, 2025 snRNA processing2006, 2012, 2025 RNA polymerase II transcription initiation surveillance2025 regulation of transcription elongation by RNA polymerase II2025 positive regulation of neuron differentiation2019 positive regulation of gene expression2019
Cellular component: integrator complex2006, 2012, 2024, 2025 nucleus2017, 2024, 2025 cytoplasm2017, 2025 INTAC complex2025 nuclear membrane2025 nucleoplasm2015 membrane2014
Phylogenetic distribution
| Chordates: | 22/21 |  |
| Echinoderms: | 0/0 | |
| Hemichordates: | 1/1 | |
| Annelids: | 1/1 | |
| Molluscs: | 0/0 | |
| Bryozoans: | 0/0 | |
| Platyhelminthes: | 0/0 | |
| Rotifers: | 0/0 | |
| Nematodes: | 3/3 | |
| Arthropods: | 5/5 | |
| Tardigrades: | 0/0 | |
| Placozoa: | 1/1 | |
| Cnidaria: | 1/1 | |
| Porifera: | 0/0 | |
| Choanoflagellates+: | 2/1 | |
| Dikarya: | 0/14 | |
| Fungi (other): | 0/1 | |
| Protozoa: | 2/3 | |
| Excavates: | 0/4 | |
| Harosa: | 1/4 | |
| Hacrobia: | 0/0 | |
| Plants: | 4/39 | |
| Archea: | 0/8 | |
| Bacteria: | 0/35 |
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Proteins
| UniProt ID Organism DB» |
Standard knownness | clustom knownness | Gene name | Description | Species [Key only] | GO terms | Seq. links | Protein domain links | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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INT2_DROME FlyBase» |
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IntS2 | Integrator complex subunit 2 |
Drosophila melanogaster TI:7227 None |
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INT2_HUMAN Ensembl» |
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INTS2 | Integrator complex subunit 2 (Int2) |
Homo sapiens TI:9606 None |
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INT2_MOUSE Ensembl» |
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Ints2 | Integrator complex subunit 2 (Int2) |
Mus musculus TI:10090 None |
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A0A096MJ28_RAT RGD» |
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Ints2 | BRCA1 interacting helicase 1 |
Rattus norvegicus TI:10116 None |
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INT2_CHICK CTD» |
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INTS2 | Integrator complex subunit 2 (Int2) |
Gallus gallus TI:9031 None |
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INT2_DICDI dictyBase» |
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ints2 | Integrator complex subunit 2 homolog |
Dictyostelium discoideum TI:44689 None |
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A0A8V1AC67_CHICK Ensembl» |
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INTS2 | Integrator complex subunit 2 |
Gallus gallus TI:9031 None |
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E5QCH1_CAEEL WormBase» |
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ints-2 | INTegrator complex Subunit homolog |
Caenorhabditis elegans TI:6239 None |
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E9QC62_DANRE ZFIN» |
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ints2 | Integrator complex subunit 2 |
Danio rerio TI:7955 None |
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A0A1L8H7Z9_XENLA Xenbase» |
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ints2.S | Integrator complex subunit 2 S homeolog isoform X1 |
Xenopus laevis TI:8355 None |
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A0A1U7YNR6_NELNU neXtProt» |
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LOC104586155 | Uncharacterized protein LOC104586155 isoform X1 |
Nelumbo nucifera TI:4432 None |
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A0A2A6CGH8_PRIPA EnsemblMetazoa» |
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WBGene00277550 | Uncharacterized protein |
Pristionchus pacificus TI:54126 None |
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A0A2K1JBF8_PHYPA EnsemblPlants» |
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LOC112292014 | Uncharacterized protein |
Physcomitrium patens TI:3218 None |
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A0A2R6WBW3_MARPO euHCVdb» |
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MARPO_0112s0002 | Uncharacterized protein |
Marchantia polymorpha TI:3197 None |
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A0A3Q1MYE6_BOVIN Ensembl» |
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INTS2 | Integrator complex subunit 2 |
Bos taurus TI:9913 None |
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A0A5F7ZF87_MACMU Ensembl» |
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INTS2 | Integrator complex subunit 2 |
Macaca mulatta TI:9544 None |
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A0A7M7P7A8_STRPU EnsemblMetazoa» |
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Integrator complex subunit 2 |
Strongylocentrotus purpuratus TI:7668 None |
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A0A803SSL8_ANOCA Ensembl» |
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Integrator complex subunit 2 |
Anolis carolinensis TI:28377 None |
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A0A8I3QCL0_CANLF Ensembl» |
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INTS2 | Integrator complex subunit 2 |
Canis lupus TI:9612 None |
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A0A9J7N5Y6_BRAFL euHCVdb» |
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LOC118425797 | Integrator complex subunit 2-like |
Branchiostoma floridae TI:7739 None |
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A0A9L0REB8_HORSE Ensembl» |
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INTS2 | Integrator complex subunit 2 |
Equus caballus TI:9796 None |
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A0ABI7ZYW7_FELCA Ensembl» |
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INTS2 | Integrator complex subunit 2 |
Felis catus TI:9685 None |
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A7RVD7_NEMVE neXtProt» |
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NEMVEDRAFT_v1g20356 | Integrator complex subunit 2 |
Nematostella vectensis TI:45351 None |
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A8WYD0_CAEBR WormBase» |
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ints-2 | Protein CBG04741 |
Caenorhabditis briggsae TI:6238 None |
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A9VDN6_MONBE neXtProt» |
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MONBRDRAFT_12899 | Uncharacterized protein |
Monosiga brevicollis TI:81824 None |
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B3RJM0_TRIAD CTD» |
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TRIADDRAFT_18353 | Integrator complex subunit 2 |
Trichoplax adhaerens TI:10228 None |
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B7PLG7_IXOSC EnsemblMetazoa» |
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IscW_ISCW005794 | Integrator complex subunit, putative |
Ixodes scapularis TI:6945 None |
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D2A4V3_TRICA neXtProt» |
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AUGUSTUS-3.0.2_15300 | Integrator complex subunit 2-like Protein |
Tribolium castaneum TI:7070 None |
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D8RWT1_SELML euHCVdb» |
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SELMODRAFT_442872 | Uncharacterized protein |
Selaginella moellendorffii TI:88036 None |
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D8TD51_SELML euHCVdb» |
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SELMODRAFT_431589 | Uncharacterized protein |
Selaginella moellendorffii TI:88036 None |
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E9FQN3_DAPPU euHCVdb» |
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DAPPUDRAFT_232326 | Uncharacterized protein |
Daphnia pulex TI:6669 None |
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E9FQN4_DAPPU neXtProt» |
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DAPPUDRAFT_232328 | Uncharacterized protein |
Daphnia pulex TI:6669 None |
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E9G4S7_DAPPU euHCVdb» |
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DAPPUDRAFT_300423 | Integrator complex subunit 2 |
Daphnia pulex TI:6669 None |
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E9GKJ8_DAPPU euHCVdb» |
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DAPPUDRAFT_244259 DAPPUDRAFT_270920 | Uncharacterized protein |
Daphnia pulex TI:6669 None |
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E9GNI1_DAPPU euHCVdb» |
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DAPPUDRAFT_319996 | Uncharacterized protein |
Daphnia pulex TI:6669 None |
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E9GPQ4_DAPPU neXtProt» |
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DAPPUDRAFT_105173 | Uncharacterized protein |
Daphnia pulex TI:6669 None |
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E9GV56_DAPPU euHCVdb» |
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DAPPUDRAFT_26173 | Uncharacterized protein |
Daphnia pulex TI:6669 None |
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E9HW39_DAPPU euHCVdb» |
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DAPPUDRAFT_66511 | Uncharacterized protein |
Daphnia pulex TI:6669 None |
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F1A4E3_DICPU TubercuList» |
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DICPUDRAFT_99991 | Integrator complex subunit 2 |
Dictyostelium purpureum TI:5786 None |
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F1S221_PIG Ensembl» |
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INTS2 | Integrator complex subunit 2 |
Sus scrofa TI:9823 None |
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F4NRX6_BATDJ euHCVdb» |
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BATDEDRAFT_84503 | Uncharacterized protein |
Batrachochytrium dendrobatidis TI:109871 None |
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F6T2D0_CIOIN Ensembl» |
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LOC100187315 | Integrator complex subunit 2 |
Ciona intestinalis TI:7719 None |
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F6TPG9_ORNAN Ensembl» |
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INTS2 | Integrator complex subunit 2 |
Ornithorhynchus anatinus TI:9258 None |
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F6UL09_XENTR Xenbase» |
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ints2 | Integrator complex subunit 2 |
Xenopus tropicalis TI:8364 None |
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F6X1I7_MONDO Ensembl» |
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INTS2 | Integrator complex subunit 2 |
Monodelphis domestica TI:13616 None |
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G3QP22_GORGO Ensembl» |
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INTS2 | Integrator complex subunit 2 |
Gorilla gorilla TI:9593 None |
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H2MAG8_ORYLA Ensembl» |
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INTS2 | Integrator complex subunit 2 |
Oryzias latipes TI:8090 None |
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H2QDL6_PANTR Ensembl» |
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INTS2 | Integrator complex subunit 2 |
Pan troglodytes TI:9598 None |
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H3HE48_PHYRM EnsemblProtists» |
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EF-hand domain-containing protein |
Phytophthora ramorum TI:164328 None |
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Q5TU39_ANOGA EnsemblMetazoa» |
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3290728 | AGAP003033-PA |
Anopheles gambiae TI:7165 None |
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T1EQB3_HELRO EnsemblMetazoa» |
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20198763 | Integrator complex subunit 2 |
Helobdella robusta TI:6412 None |
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W5M7Q9_LEPOC Ensembl» |
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Integrator complex subunit 2 |
Lepisosteus oculatus TI:7918 None |
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