Collated Gene Ontology terms

Biological process: calcium ion binding(2025)

Molecular function: snRNA 3'-end processing2012, 2017, 2025 snRNA processing2006, 2012, 2025 RNA polymerase II transcription initiation surveillance2025 regulation of transcription elongation by RNA polymerase II2025 positive regulation of neuron differentiation2019 positive regulation of gene expression2019

Cellular component: integrator complex2006, 2012, 2024, 2025 nucleus2017, 2024, 2025 cytoplasm2017, 2025 INTAC complex2025 nuclear membrane2025 nucleoplasm2015 membrane2014

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 2/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 1/4 
Hacrobia: 0/0 
Plants: 4/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
INT2_DROME
FlyBase»
4.2
IntS2 Integrator complex subunit 2 Drosophila melanogaster
TI:7227 None
 
INT2_HUMAN
Ensembl»
4.1
INTS2 Integrator complex subunit 2 (Int2) Homo sapiens
TI:9606 None
 
INT2_MOUSE
Ensembl»
3.0
Ints2 Integrator complex subunit 2 (Int2) Mus musculus
TI:10090 None
 
A0A096MJ28_RAT
RGD»
2.0
Ints2 BRCA1 interacting helicase 1 Rattus norvegicus
TI:10116 None
   
INT2_CHICK
CTD»
1.0
INTS2 Integrator complex subunit 2 (Int2) Gallus gallus
TI:9031 None
 
INT2_DICDI
dictyBase»
1.0
ints2 Integrator complex subunit 2 homolog Dictyostelium discoideum
TI:44689 None
 
A0A8V1AC67_CHICK
Ensembl»
0.5
INTS2 Integrator complex subunit 2 Gallus gallus
TI:9031 None
   
E5QCH1_CAEEL
WormBase»
0.5
ints-2 INTegrator complex Subunit homolog Caenorhabditis elegans
TI:6239 None
 
E9QC62_DANRE
ZFIN»
0.5
ints2 Integrator complex subunit 2 Danio rerio
TI:7955 None