Collated Gene Ontology terms

Biological process: catalytic activity(2025)

Molecular function: synaptic vesicle endocytosis2024, 2025 synaptic vesicle budding from endosome2024, 2025 endocytosis2025

Cellular component: nucleus2021, 2022, 2025 extrinsic component of synaptic vesicle membrane2024, 2025 presynapse2025 nucleoplasm2024, 2025 cytoplasmic vesicle2025 clathrin-coated vesicle2025 synaptic vesicle2018, 2025 neuron projection terminus2018, 2025 axon2025 AP-2 adaptor complex2018, 2025
cytoplasm2022

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 0/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 1/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 2/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 1/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
BTBD8_MOUSE
Ensembl»
4.8
Btbd8 BTB/POZ domain-containing protein 8
(AP2-interacting clathrin-endocytosis protein) (APache)		 Mus musculus
TI:10090 None
 
BTBD8_RAT
RGD»
1.0
Btbd8 BTB/POZ domain-containing protein 8
(AP2-interacting clathrin-endocytosis protein) (APache)		 Rattus norvegicus
TI:10116 None
 
BTBD8_HUMAN
Ensembl»
0.0
BTBD8 BTB/POZ domain-containing protein
8 (AP2-interacting clathrin-endocytosis) (APache)		 Homo sapiens
TI:9606 None
 
A0A5F8A6B3_MACMU
Ensembl»
0.0
C1H1orf146 BTB/POZ domain-containing protein 8 Macaca mulatta
TI:9544 None
   
A0A286ZV78_PIG
Ensembl»
0.0
BTBD8 BTB/POZ domain-containing protein 8 Sus scrofa
TI:9823 None
   
A0A8V0ZNI0_CHICK
Ensembl»
0.0
BTB/POZ domain-containing protein 8 Gallus gallus
TI:9031 None
   
F7GDE7_MONDO
Ensembl»
0.0
BTBD8 BTB/POZ domain-containing protein 8 Monodelphis domestica
TI:13616 None
   
G1KD12_ANOCA
Ensembl»
0.0
BTBD8 BTB/POZ domain-containing protein 8 Anolis carolinensis
TI:28377 None
   
A0A6I8NZH3_ORNAN
Ensembl»
0.0
BTBD8 BTB/POZ domain-containing protein 8 Ornithorhynchus anatinus
TI:9258 None
   
G3RBU6_GORGO
Ensembl»
0.0
BTBD8 BTB/POZ domain-containing protein 8 Gorilla gorilla
TI:9593 None
 
G3S0L3_GORGO
Ensembl»
0.0
BTBD8 BTB domain containing 8 Gorilla gorilla
TI:9593 None
 
H2PZE1_PANTR
Ensembl»
0.0
BTBD8 BTB/POZ domain-containing protein 8 Pan troglodytes
TI:9598 None
 
H2PZE2_PANTR
Ensembl»
0.0
KIAA1107 Symbol withdrawn,
see [HGNC:21019](/data/-symbol-report/#!/hgnc_id/HGNC:21019)		 Pan troglodytes
TI:9598 None
 
A0A3B3H4M2_ORYLA
Ensembl»
0.0
prr36b BTB/POZ domain-containing protein Oryzias latipes
TI:8090 None
   
A0A1L8H2K2_XENLA
CTD»
0.0
LOC108711676 Mucin-17 Xenopus laevis
TI:8355 None 		     
A0A2A6CFS9_PRIPA
EnsemblMetazoa»
0.0
WBGene00276802 BTB domain-containing protein Pristionchus pacificus
TI:54126 None 		     
A0A2K3DPY1_CHLRE
euHCVdb»
0.0
CHLRE_06g285451v5 BTBD8 BACK domain-containing protein Chlamydomonas reinhardtii
TI:3055 None 		 
 
A0A3B3IHP2_ORYLA
Ensembl»
0.0
btbd8 BTB domain containing 8 Oryzias latipes
TI:8090 None 		     
A0A3B3IKG9_ORYLA
Ensembl»
0.0
prr36a BTB/POZ domain-containing protein Oryzias latipes
TI:8090 None 		     
A0A3Q2H1Y0_HORSE
Ensembl»
0.0
PRR36 Proline rich 36 Equus caballus
TI:9796 None 		     
A0A6I8P7T5_ORNAN
Ensembl»
0.0
LOC103166610 BTB/POZ domain-containing protein Ornithorhynchus anatinus
TI:9258 None 		     
A0A6I8RCA2_XENTR
Xenbase»
0.0
prr36 Proline rich 36 (Proline-rich protein 36) Xenopus tropicalis
TI:8364 None 		     
A0A7D9NKS2_XENTR
Xenbase»
0.0
btbd8 AP2-interacting clathrin-endocytosis protein isoform
X1 (BTB domain-containing 8)		 Xenopus tropicalis
TI:8364 None 		     
A0A7M7GLN6_STRPU
EnsemblMetazoa»
0.0
BTB domain-containing protein Strongylocentrotus purpuratus
TI:7668 None 		     
A0A7M7PMJ1_STRPU
EnsemblMetazoa»
0.0
BTB domain-containing protein Strongylocentrotus purpuratus
TI:7668 None 		     
A0A803TKP7_ANOCA
Ensembl»
0.0
prr36 BTB/POZ domain-containing protein Anolis carolinensis
TI:28377 None 		     
A0A8I3P0X9_CANLF
Ensembl»
0.0
BTBD8 BTB domain containing 8 Canis lupus
TI:9612 None 		     
A0A8I3Q0P0_CANLF
Ensembl»
0.0
PRR36 Proline rich 36 Canis lupus
TI:9612 None 		     
A0A8J0V5H4_XENLA
CTD»
0.0
btbd8.S AP2-interacting clathrin-endocytosis
protein isoform X1		 Xenopus laevis
TI:8355 None 		     
A0A8N7UTE4_DANRE
CTD»
0.0
prr36b Uncharacterized protein prr36b Danio rerio
TI:7955 None 		       
A0A9J7KY65_BRAFL
euHCVdb»
0.0
LOC118413228 Serine/arginine repetitive matrix protein 2-like Branchiostoma floridae
TI:7739 None 		     
A0A9L0TA31_HORSE
Ensembl»
0.0
BTBD8 BTB domain containing 8 Equus caballus
TI:9796 None 		     
A0ABI0NRG9_BOVIN
Ensembl»
0.0
BTBD8 BTB domain containing 8 Bos taurus
TI:9913 None 		     
A0ABI7XIE8_FELCA
Ensembl»
0.0
BTB domain-containing protein Felis catus
TI:9685 None 		     
A0ABI8AMD2_FELCA
Ensembl»
0.0
PRR36 BTB/POZ domain-containing protein Felis catus
TI:9685 None 		     
A0ACD6B7I8_DANRE
ZFIN»
0.0
btbd8 BTB/POZ domain-containing protein 8 isoform X1 Danio rerio
TI:7955 None 		     
A7RXL4_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g203648 BTB domain-containing protein Nematostella vectensis
TI:45351 None 		 
 
A7TC02_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g225020 BTBD8 BACK domain-containing protein Nematostella vectensis
TI:45351 None 		 
 
B3RQV1_TRIAD
CTD»
0.0
TRIADDRAFT_54008 BTB domain-containing protein Trichoplax adhaerens
TI:10228 None 		 
 
B7P9I2_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW001881 BTB domain-containing protein Ixodes scapularis
TI:6945 None 		 
 
D3ZUH5_RAT
RGD»
0.0
Prr36 Proline rich 36 Rattus norvegicus
TI:10116 None 		     
D6WGC3_TRICA
CTD»
0.0
AUGUSTUS-3.0.2_10343 BTB domain-containing protein Tribolium castaneum
TI:7070 None 		 
 
E3JXN9_PUCGT
TubercuList»
0.0
PGTG_02275 CAP-Gly domain-containing protein Puccinia graminis
TI:5297 None 		 
 
E9HAN6_DAPPU
neXtProt»
0.0
DAPPUDRAFT_327405 BTB domain-containing protein Daphnia pulex
TI:6669 None 		 
 
E9PV26_MOUSE
Ensembl»
0.0
Prr36 Proline rich 36 Mus musculus
TI:10090 None 		     
F1SA83_PIG
Ensembl»
0.0
PRR36 Proline rich 36 Sus scrofa
TI:9823 None 		     
F6P0E6_DANRE
ZFIN»
0.0
prr36a Mucin-4 (Si:ch211-214c7.4) Danio rerio
TI:7955 None 		 
 
F6UQS9_CIOIN
Ensembl»
0.0
BTBD8 BACK domain-containing protein Ciona intestinalis
TI:7719 None 		     
F7AVI8_MACMU
Ensembl»
0.0
PRR36 Proline rich 36 Macaca mulatta
TI:9544 None 		     
G3QHV4_GORGO
Ensembl»
0.0
PRR36 Proline rich 36 Gorilla gorilla
TI:9593 None 		 
 
H2QF74_PANTR
Ensembl»
0.0
PRR36 Proline rich 36 Pan troglodytes
TI:9598 None 		 
 
PRR36_HUMAN
Ensembl»
0.0
PRR36 Proline-rich protein 36 Homo sapiens
TI:9606 None 		 
 
Q3SYN0_XENLA
Xenbase»
0.0
btbd8.L BTB domain containing 8
L homeolog (MGC115245 protein)		 Xenopus laevis
TI:8355 None 		 
 
Q5KHQ5_CRYD1
TubercuList»
0.0
CND05670 Expressed protein Cryptococcus deneoformans
TI:40410 None 		 
 
Q7Q6M4_ANOGA
EnsemblMetazoa»
0.0
1276435 AGAP005765-PA Anopheles gambiae
TI:7165 None 		 
 
Q9W0D3_DROME
FlyBase»
0.0
Dmel\CG13917 GH15728p Drosophila melanogaster
TI:7227 None 		 
 
W5MBN6_LEPOC
Ensembl»
0.0
BTB domain containing 8 Lepisosteus oculatus
TI:7918 None 		 
 
W5MI15_LEPOC
Ensembl»
0.0
BTB/POZ domain-containing protein Lepisosteus oculatus
TI:7918 None