Collated Gene Ontology terms

Biological process: guanyl-nucleotide exchange factor activity(2013, 2021, 2022, 2024) glycine-tRNA ligase activity(2024) ATP binding(2024)

Molecular function: axon guidance2021 regulation of small GTPase mediated signal transduction2024 intracellular signal transduction2024 regulation of locomotor rhythm2015 positive regulation of Rho protein signal transduction2013 neuron projection morphogenesis2015 mesoderm morphogenesis2004 imaginal disc-derived leg morphogenesis2012 glycyl-tRNA aminoacylation2024 cell-cell adhesion2024
animal organ morphogenesis2004 activation of GTPase activity2013

Cellular component: plasma membrane2022, 2023, 2024 cytosol2017, 2020, 2021, 2023, 2024 cytoplasm2022, 2024 extrinsic component of membrane2023 nucleus2024 basal plasma membrane2024 membrane2024 cell-cell junction2024 anchoring junction2024

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
PKH4B_HUMAN
Ensembl»
4.4
PLEKHG4B Pleckstrin homology domain-containing family G member
4B (PH domain-containing family G member 4B)		 Homo sapiens
TI:9606 None
 
ARH40_HUMAN
Ensembl»
2.8
ARHGEF40 Rho guanine nucleotide exchange
factor 40 (Protein SOLO)		 Homo sapiens
TI:9606 None
 
PKHG4_HUMAN
Ensembl»
2.8
PLEKHG4 Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (PH
domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1)		 Homo sapiens
TI:9606 None
 
Q7KU89_DROME
FlyBase»
3.4
Pura Puratrophin-1-like, isoform A Drosophila melanogaster
TI:7227 None
 
K1755_HUMAN
Ensembl»
1.0
KIAA1755 Uncharacterized protein KIAA1755 Homo sapiens
TI:9606 None
   
A0A0G2JZE7_RAT
RGD»
0.0
Arhgef40 Rho guanine nucleotide exchange factor 40 Rattus norvegicus
TI:10116 None
   
Q6DN89_DANRE
ZFIN»
1.6
sb:cb9 Quattro Danio rerio
TI:7955 None
 
ARH40_MOUSE
Ensembl»
0.0
Arhgef40 Rho guanine nucleotide exchange
factor 40 (Protein SOLO)		 Mus musculus
TI:10090 None
 
F8VPS6_MOUSE
Ensembl»
0.8
Plekhg4 Pleckstrin homology domain containing, family
G (with RhoGef domain) member 4		 Mus musculus
TI:10090 None
   
A0A8I6AG98_RAT
RGD»
0.0
Plekhg4 Pleckstrin homology and
RhoGEF domain containing G4		 Rattus norvegicus
TI:10116 None
   
A0A8V0ZJ14_CHICK
Ensembl»
0.0
PLEKHG4 Pleckstrin homology and
RhoGEF domain containing G4		 Gallus gallus
TI:9031 None
   
E7F579_DANRE
ZFIN»
0.0
arhgef40 Pleckstrin homology domain-containing family G member 4B
(Rho guanine nucleotide exchange factor (GEF) 40)		 Danio rerio
TI:7955 None
 
E7FCG7_DANRE
ZFIN»
0.0
si:dkey-65j6.2 Pleckstrin homology domain-containing family G
member 4B isoform X1 (Si:dkey-65j6.2)		 Danio rerio
TI:7955 None
 
E7FEK1_DANRE
ZFIN»
0.0
plekhg4 Pleckstrin homology domain-containing, family G (with RhoGef
domain) member 4 (Uncharacterized protein plekhg4 isoform X1)		 Danio rerio
TI:7955 None
 
A0A8V0YIP1_CHICK
Ensembl»
0.0
KIAA1755 KIAA1755 Gallus gallus
TI:9031 None 		       
A2RV33_DANRE
ZFIN»
0.0
zgc:158766 Uncharacterized protein
LOC100009641 (Zgc:158766 protein)		 Danio rerio
TI:7955 None 		 
   
F1M4P5_RAT
RGD»
0.0
Kiaa1755 RIKEN cDNA D630003M21 gene Rattus norvegicus
TI:10116 None 		       
K1755_MOUSE
Ensembl»
0.0
Uncharacterized protein KIAA1755 homolog Mus musculus
TI:10090 None