Standard knownness: 4.4; Custom knownness: None; Num. species: 30; Orthology database: Panther19.0; Protein members: 91
                   Molecular function:
                   
                     axon guidance2021
                   
                     regulation of small GTPase mediated signal transduction2024
                   
                     intracellular signal transduction2024
                   
                     regulation of locomotor rhythm2015
                   
                     positive regulation of Rho protein signal transduction2013
                   
                     neuron projection morphogenesis2015
                   
                     mesoderm morphogenesis2004
                   
                     imaginal disc-derived leg morphogenesis2012
                   
                     glycyl-tRNA aminoacylation2024
                   
                     cell-cell adhesion2024
                   
                   
                      
                      
                      
                        
                          animal organ morphogenesis2004
                        
                          activation of GTPase activity2013
                        
                      
                    
                   
Cellular component: plasma membrane2022, 2023, 2024 cytosol2017, 2020, 2021, 2023, 2024 cytoplasm2022, 2024 extrinsic component of membrane2023 nucleus2024 basal plasma membrane2024 membrane2024 cell-cell junction2024 anchoring junction2024
| Chordates: | 22/21 | ![]()  | 
                   
                 
| Echinoderms: | 0/0 | |
| Hemichordates: | 1/1 | |
| Annelids: | 1/1 | |
| Molluscs: | 0/0 | |
| Bryozoans: | 0/0 | |
| Platyhelminthes: | 0/0 | |
| Rotifers: | 0/0 | |
| Nematodes: | 0/3 | |
| Arthropods: | 5/5 | |
| Tardigrades: | 0/0 | |
| Placozoa: | 0/1 | |
| Cnidaria: | 1/1 | |
| Porifera: | 0/0 | |
| Choanoflagellates+: | 0/1 | |
| Dikarya: | 0/14 | |
| Fungi (other): | 0/1 | |
| Protozoa: | 0/3 | |
| Excavates: | 0/4 | |
| Harosa: | 0/4 | |
| Hacrobia: | 0/0 | |
| Plants: | 0/39 | |
| Archea: | 0/8 | |
| Bacteria: | 0/35 | 
Click here to switch to the previous version of the database.
| UniProt ID Organism DB»  | 
	    
        
          
            Standard knownness | clustom knownness | Gene name | Description | Species [Show all] | GO terms | Seq. links | Protein domain links | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 
        K1755_MOUSE Ensembl»  | 
        
          
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        Uncharacterized protein KIAA1755 homolog | 
        Mus musculus TI:10090 None  | 
        
          
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| 
        ARH40_HUMAN Ensembl»  | 
        
          
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        ARHGEF40 | Rho guanine nucleotide exchange factor 40 (Protein SOLO)  | 
        
        Homo sapiens TI:9606 None  | 
        
          
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| 
        A0A0G2JZE7_RAT RGD»  | 
        
          
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        Arhgef40 | Rho guanine nucleotide exchange factor 40 | 
        Rattus norvegicus TI:10116 None  | 
        
          
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| 
        ARH40_MOUSE Ensembl»  | 
        
          
  | 
        
          
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        Arhgef40 | Rho guanine nucleotide exchange factor 40 (Protein SOLO)  | 
        
        Mus musculus TI:10090 None  | 
        
          
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| 
        A0A8V0YIP1_CHICK Ensembl»  | 
        
          
  | 
        
          
  | 
        KIAA1755 | KIAA1755 | 
        Gallus gallus TI:9031 None  | 
        ||||||||
| 
        K1755_HUMAN Ensembl»  | 
        
          
  | 
        
          
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        KIAA1755 | Uncharacterized protein KIAA1755 | 
        Homo sapiens TI:9606 None  | 
        
          
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| 
        F1M4P5_RAT RGD»  | 
        
          
  | 
        
          
  | 
        Kiaa1755 | RIKEN cDNA D630003M21 gene | 
        Rattus norvegicus TI:10116 None  | 
        ||||||||
| 
        A0A8V0ZJ14_CHICK Ensembl»  | 
        
          
  | 
        
          
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        PLEKHG4 | Pleckstrin homology and RhoGEF domain containing G4  | 
        
        Gallus gallus TI:9031 None  | 
        
          
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| 
        PKHG4_HUMAN Ensembl»  | 
        
          
  | 
        
          
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        PLEKHG4 | Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (PH domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1)  | 
        
        Homo sapiens TI:9606 None  | 
        
          
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        |||||
| 
        PKH4B_HUMAN Ensembl»  | 
        
          
  | 
        
          
  | 
        PLEKHG4B | Pleckstrin homology domain-containing family G member 4B (PH domain-containing family G member 4B)  | 
        
        Homo sapiens TI:9606 None  | 
        
          
           | 
        
          
           | 
        
          
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        |||||
| 
        A0A8I6AG98_RAT RGD»  | 
        
          
  | 
        
          
  | 
        Plekhg4 | Pleckstrin homology and RhoGEF domain containing G4  | 
        
        Rattus norvegicus TI:10116 None  | 
        
          
           | 
        
          
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| 
        F8VPS6_MOUSE Ensembl»  | 
        
          
  | 
        
          
  | 
        Plekhg4 | Pleckstrin homology domain containing, family G (with RhoGef domain) member 4  | 
        
        Mus musculus TI:10090 None  | 
        
          
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        ||||||
| 
        Q7KU89_DROME FlyBase»  | 
        
          
  | 
        
          
  | 
        Pura | Puratrophin-1-like, isoform A | 
        Drosophila melanogaster TI:7227 None  | 
        
          
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| 
        E7F579_DANRE ZFIN»  | 
        
          
  | 
        
          
  | 
        arhgef40 | Pleckstrin homology domain-containing family G member 4B (Rho guanine nucleotide exchange factor (GEF) 40)  | 
        
        Danio rerio TI:7955 None  | 
        
          
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| 
        E7FEK1_DANRE ZFIN»  | 
        
          
  | 
        
          
  | 
        plekhg4 | Pleckstrin homology domain-containing, family G (with RhoGef domain) member 4 (Uncharacterized protein plekhg4 isoform X1)  | 
        
        Danio rerio TI:7955 None  | 
        
          
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| 
        Q6DN89_DANRE ZFIN»  | 
        
          
  | 
        
          
  | 
        sb:cb9 | Quattro | 
        Danio rerio TI:7955 None  | 
        
          
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| 
        E7FCG7_DANRE ZFIN»  | 
        
          
  | 
        
          
  | 
        si:dkey-65j6.2 | Pleckstrin homology domain-containing family G member 4B isoform X1 (Si:dkey-65j6.2)  | 
        
        Danio rerio TI:7955 None  | 
        
          
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        |||||
| 
        A2RV33_DANRE ZFIN»  | 
        
          
  | 
        
          
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        zgc:158766 | Uncharacterized protein LOC100009641 (Zgc:158766 protein)  | 
        
        Danio rerio TI:7955 None  | 
        
          
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        |||||||