Collated Gene Ontology terms

Biological process: guanyl-nucleotide exchange factor activity(2013, 2021, 2024, 2025) nucleotide binding(2025) glycine-tRNA ligase activity(2025) ATP binding(2025)

Molecular function: cell-cell adhesion2024, 2025 axon guidance2021 regulation of small GTPase mediated signal transduction2025 intracellular signal transduction2025 regulation of locomotor rhythm2015 positive regulation of Rho protein signal transduction2013 neuron projection morphogenesis2015 mesoderm morphogenesis2004 imaginal disc-derived leg morphogenesis2012 glycyl-tRNA aminoacylation2025
animal organ morphogenesis2004

Cellular component: cytosol2017, 2020, 2021, 2025 cytoplasm2024, 2025 nucleus2024, 2025 basal plasma membrane2024, 2025 plasma membrane2024, 2025 cell-cell junction2024, 2025 extrinsic component of membrane2024 anchoring junction2025 hemidesmosome2025 cytoskeleton2025

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
A0A8I5ZUE2_RAT
RGD»
0.0
Arhgef40 Rho guanine nucleotide exchange factor 40 Rattus norvegicus
TI:10116 None
   
A0A8V0YIP1_CHICK
Ensembl»
0.0
KIAA1755 KIAA1755 Gallus gallus
TI:9031 None 		     
A0A8V0ZJ14_CHICK
Ensembl»
0.0
PLEKHG4 Pleckstrin homology and
RhoGEF domain containing G4		 Gallus gallus
TI:9031 None
   
A0ABK0LL84_RAT
RGD»
0.0
Plekhg4 Pleckstrin homology and
RhoGEF domain containing G4		 Rattus norvegicus
TI:10116 None
   
ARH40_MOUSE
Ensembl»
0.0
Arhgef40 Rho guanine nucleotide exchange factor
40 (Protein SOLO) (Scambio) (Sabi)		 Mus musculus
TI:10090 None
 
E7F579_DANRE
ZFIN»
0.0
arhgef40 Rho guanine nucleotide exchange factor (GEF)
40 (Rho guanine nucleotide exchange factor 40)		 Danio rerio
TI:7955 None
 
E7FCG7_DANRE
ZFIN»
0.0
quoa Pleckstrin homology domain-containing family G
member 4B isoform X1 (Si:dkey-65j6.2)		 Danio rerio
TI:7955 None
 
K1755_MOUSE
Ensembl»
0.0
Uncharacterized protein KIAA1755 homolog Mus musculus
TI:10090 None 		 
 
F8VPS6_MOUSE
Ensembl»
0.8
Plekhg4 Pleckstrin homology domain containing, family
G (with RhoGef domain) member 4		 Mus musculus
TI:10090 None
   
K1755_HUMAN
Ensembl»
1.0
KIAA1755 Uncharacterized protein KIAA1755 Homo sapiens
TI:9606 None
 
A0AB32TQS0_DANRE
ZFIN»
1.6
quob Quattro isoform X1 Danio rerio
TI:7955 None
   
ARH40_HUMAN
Ensembl»
2.8
ARHGEF40 Rho guanine nucleotide exchange factor
40 (Protein SOLO) (Scambio) (Sabi)		 Homo sapiens
TI:9606 None
 
PKHG4_HUMAN
Ensembl»
2.8
PLEKHG4 Puratrophin-1 (Pleckstrin homology domain-containing family G member 4) (PH
domain-containing family G member 4) (Purkinje cell atrophy-associated protein 1)		 Homo sapiens
TI:9606 None
 
Q7KU89_DROME
FlyBase»
3.4
Pura Puratrophin-1-like, isoform A Drosophila melanogaster
TI:7227 None
 
PKH4B_HUMAN
Ensembl»
4.4
PLEKHG4B Pleckstrin homology domain-containing family G member
4B (PH domain-containing family G member 4B)		 Homo sapiens
TI:9606 None