Cluster UKP08651
- NEGATIVE ELONGATION FACTOR D
Standard knownness: 3.4; Custom knownness: None; Num. species: 39; Orthology database: Panther19.0; Protein members: 42
Collated Gene Ontology terms
Molecular function: negative regulation of transcription elongation by RNA polymerase II2011, 2022, 2024 negative regulation of DNA-templated transcription2024 translational elongation2024 negative regulation of transcription by RNA polymerase II2018 mRNA splicing, via spliceosome2017
Cellular component:
NELF complex2011, 2012, 2019, 2022, 2024
nucleus2011, 2022, 2024
membrane2014, 2024
transcription repressor complex2003
transcription elongation factor complex2006
polytene chromosome puff2006
polytene chromosome interband2006
nucleoplasm2013
chromosome2024
U2-type prespliceosome2017
U1 snRNP2017
Phylogenetic distribution
| Chordates: | 21/21 |  |
| Echinoderms: | 0/0 | |
| Hemichordates: | 1/1 | |
| Annelids: | 1/1 | |
| Molluscs: | 0/0 | |
| Bryozoans: | 0/0 | |
| Platyhelminthes: | 0/0 | |
| Rotifers: | 0/0 | |
| Nematodes: | 0/3 | |
| Arthropods: | 5/5 | |
| Tardigrades: | 0/0 | |
| Placozoa: | 1/1 | |
| Cnidaria: | 1/1 | |
| Porifera: | 0/0 | |
| Choanoflagellates+: | 2/1 | |
| Dikarya: | 0/14 | |
| Fungi (other): | 0/1 | |
| Protozoa: | 2/3 | |
| Excavates: | 1/4 | |
| Harosa: | 3/4 | |
| Hacrobia: | 0/0 | |
| Plants: | 1/39 | |
| Archea: | 0/8 | |
| Bacteria: | 0/35 |
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Proteins
| UniProt ID Organism DB» |
Standard knownness | clustom knownness | Gene name | Description | Species [Key only] | GO terms | Seq. links | Protein domain links | |||||
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NELFD_DROME FlyBase» |
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TH1 | Negative elongation factor D |
Drosophila melanogaster TI:7227 None |
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NELFD_HUMAN Ensembl» |
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NELFCD | Negative elongation factor C/D (NELF-C/D) (TH1-like protein) |
Homo sapiens TI:9606 None |
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A0A8I6B5Y3_RAT RGD» |
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Nelfcd | Negative elongation factor complex member C/D |
Rattus norvegicus TI:10116 None |
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Q55F13_DICDI dictyBase» |
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DDB_G0268678 | TH1 family protein |
Dictyostelium discoideum TI:44689 None |
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Q5ZIQ8_CHICK Ensembl» |
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NELFCD | Negative elongation factor complex member C/D |
Gallus gallus TI:9031 None |
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Q7ZVZ0_DANRE ZFIN» |
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th1l | Negative elongation factor C/D (TH1-like (Drosophila)) |
Danio rerio TI:7955 None |
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A0A1D5RAZ2_MACMU Ensembl» |
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NELFCD | Negative elongation factor complex member C/D |
Macaca mulatta TI:9544 None |
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A0A1L8ET09_XENLA Xenbase» |
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nelfcd.L | Negative elongation factor D |
Xenopus laevis TI:8355 None |
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A0A2I2ZQD7_GORGO Ensembl» |
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NELFCD | Negative elongation factor complex member C/D |
Gorilla gorilla TI:9593 None |
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A0A2K3DY54_CHLRE EnsemblPlants» |
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CHLRE_03g187550v5 | Uncharacterized protein |
Chlamydomonas reinhardtii TI:3055 None |
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A0A7M7SV66_STRPU EnsemblMetazoa» |
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Negative elongation factor D |
Strongylocentrotus purpuratus TI:7668 None |
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A0A803TY53_ANOCA Ensembl» |
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NELFCD | Negative elongation factor complex member C/D |
Anolis carolinensis TI:28377 None |
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A0A8I3NUK3_CANLF Ensembl» |
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NELFCD | Negative elongation factor complex member C/D |
Canis lupus TI:9612 None |
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A2EY60_TRIV3 VEuPathDB» |
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TVAG_206820 | Symplekin C-terminal domain-containing protein |
Trichomonas vaginalis TI:5722 None |
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A2GBU2_TRIV3 VEuPathDB» |
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TVAG_225160 | Uncharacterized protein |
Trichomonas vaginalis TI:5722 None |
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A7RMD1_NEMVE EnsemblMetazoa» |
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NEMVEDRAFT_v1g199243 | Negative elongation factor D |
Nematostella vectensis TI:45351 None |
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A7T2E6_NEMVE EnsemblMetazoa» |
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NEMVEDRAFT_v1g176382 | Negative elongation factor D |
Nematostella vectensis TI:45351 None |
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A9VB53_MONBE EnsemblProtists» |
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MONBRDRAFT_29453 | Sugar phosphate transporter domain-containing protein |
Monosiga brevicollis TI:81824 None |
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B3RV68_TRIAD EnsemblMetazoa» |
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TRIADDRAFT_55545 | Negative elongation factor D |
Trichoplax adhaerens TI:10228 None |
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B7PEW0_IXOSC EnsemblMetazoa» |
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8050449 | Negative elongation factor C/D, putative |
Ixodes scapularis TI:6945 None |
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B8C2S7_THAPS EnsemblProtists» |
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THAPSDRAFT_22716 | WW domain-containing protein |
Thalassiosira pseudonana TI:35128 None |
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C3YGG3_BRAFL CTD» |
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LOC118418469 | Negative elongation factor D-like |
Branchiostoma floridae TI:7739 None |
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D6WGW8_TRICA EnsemblMetazoa» |
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AUGUSTUS-3.0.2_03474 | Negative elongation factor D-like Protein |
Tribolium castaneum TI:7070 None |
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E9G5E8_DAPPU EnsemblMetazoa» |
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EOG090X02QS | EOG090X02QS |
Daphnia pulex TI:6669 None |
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F1A0C4_DICPU EnsemblProtists» |
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DICPUDRAFT_157917 | TH1 family protein |
Dictyostelium purpureum TI:5786 None |
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F1MW69_BOVIN Ensembl» |
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NELFCD | Negative elongation factor complex member C/D |
Bos taurus TI:9913 None |
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F4P297_BATDJ EnsemblBacteria» |
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BATDEDRAFT_88143 | DNA mismatch repair protein HSM3 N-terminal domain-containing protein |
Batrachochytrium dendrobatidis TI:109871 None |
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F6ZD99_MONDO Ensembl» |
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NELFCD | Negative elongation factor complex member C/D |
Monodelphis domestica TI:13616 None |
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F6ZDB4_CIOIN Ensembl» |
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LOC100183995 | Negative elongation factor C/D |
Ciona intestinalis TI:7719 None |
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F7EJ98_ORNAN Ensembl» |
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NELFCD | Negative elongation factor complex member C/D |
Ornithorhynchus anatinus TI:9258 None |
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H2MIJ8_ORYLA Ensembl» |
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nelfcd | Negative elongation factor complex member C/D |
Oryzias latipes TI:8090 None |
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H2QKN7_PANTR Ensembl» |
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NELFCD | Negative elongation factor complex member C/D (TH1-like) |
Pan troglodytes TI:9598 None |
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H3GE46_PHYRM EnsemblProtists» |
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WW domain-containing protein |
Phytophthora ramorum TI:164328 None |
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K7GPN5_PIG Ensembl» |
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NELFCD | Negative elongation factor complex member C/D |
Sus scrofa TI:9823 None |
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M3VVI6_FELCA Ensembl» |
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NELFCD | Negative elongation factor complex member C/D |
Felis catus TI:9685 None |
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NELFD_MOUSE Ensembl» |
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Nelfcd | Negative elongation factor D (NELF-D) (TH1-like protein) |
Mus musculus TI:10090 None |
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NELFD_PIG Ensembl» |
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NELFCD | Negative elongation factor D (NELF-D) (TH1-like protein) |
Sus scrofa TI:9823 None |
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Q566L2_XENTR Xenbase» |
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nelfcd | GNAS complex locus (Negative elongation factor C/D) (Th1l protein) |
Xenopus tropicalis TI:8364 None |
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Q7QFB3_ANOGA EnsemblMetazoa» |
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1271857 | AGAP000391-PA |
Anopheles gambiae TI:7165 None |
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Q9U0K9_PLAF7 EnsemblProtists» |
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PF3D7_0407700 | Uncharacterized protein |
Plasmodium falciparum TI:5833 None |
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T1EMI2_HELRO EnsemblMetazoa» |
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20197782 | Negative elongation factor C/D |
Helobdella robusta TI:6412 None |
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W5MGP7_LEPOC Ensembl» |
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Negative elongation factor complex member C/D |
Lepisosteus oculatus TI:7918 None |
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