Collated Gene Ontology terms

Biological process: guanyl-nucleotide exchange factor activity(2005, 2010, 2012, 2016, 2021, 2024, 2025) identical protein binding(2023, 2025) small GTPase binding(2023) GTPase binding(2005, 2025) phosphatidylinositol-4-phosphate binding(2013) kinase binding(2011, 2025)

Molecular function: protein transport2025 protein targeting to membrane2014, 2025 exocytosis2005, 2013, 2025 cilium assembly2008, 2025 negative regulation of filopodium assembly2016, 2025 ascospore-type prospore membrane formation2010, 2021, 2025 sporulation resulting in formation of a cellular spore2021, 2025 protein localization to meiotic spindle pole body2017, 2025 autophagy2013 ascospore-type prospore-specific spindle pole body remodeling2008, 2025
ascospore formation2008, 2025 meiotic cell cycle2025 intracellular protein transport2005 hyphal growth2014 filamentous growth2014 ciliary basal body-plasma membrane docking2025 Golgi to plasma membrane transport2008

Cellular component: cytosol2005, 2013, 2014, 2016, 2024, 2025 cell tip2009, 2020 nucleus2005, 2025 centrosome2024, 2025 nucleoplasm2024, 2025 meiotic spindle pole body2016, 2017, 2024, 2025 cytoplasm2006, 2025 cellular bud neck2013, 2018, 2025 Golgi to plasma membrane transport vesicle2014, 2025 transport vesicle2013, 2025
proximal dendrite2016, 2025 perinuclear region of cytoplasm2016, 2025 lamellipodium2025 cytoskeleton2025 cellular bud tip2013, 2025 vesicle2025 prospore membrane2016, 2025 meiotic spindle pole2017, 2025 medial cortical node2016, 2025 cytoplasmic vesicle2025 cell cortex of cell tip2016, 2025 spitzenkorper2014 spindle pole body2025 mating projection tip2018 ciliary basal body2008 cell division site2009

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 3/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 15/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
RAB3I_HUMAN
Ensembl»
7.3
RAB3IP Rab-3A-interacting protein (Rab3A-interacting protein)
(Rabin-3) (Rabin8) (SSX2-interacting protein)		 Homo sapiens
TI:9606 None
 
RAB3I_RAT
RGD»
6.9
Rab3ip Rab-3A-interacting protein (Rab3A-interacting
protein) (Rabin-3) (SSX2-interacting protein)		 Rattus norvegicus
TI:10116 None
 
R3GEF_HUMAN
Ensembl»
3.0
RAB3IL1 Guanine nucleotide exchange factor for Rab-3A (Rab-3A-interacting-like
protein 1) (Rab3A-interacting-like protein 1) (Rabin3-like 1)		 Homo sapiens
TI:9606 None
 
R3GEF_MOUSE
Ensembl»
2.5
Rab3il1 Guanine nucleotide exchange factor for Rab-3A (Rab-3A-interacting-like
protein 1) (Rab3A-interacting-like protein 1) (Rabin3-like 1)		 Mus musculus
TI:10090 None
 
SEC2_YEAST
SGD»
7.7
SEC2 Rab guanine nucleotide exchange factor
SEC2 (GDP-GTP exchange factor SEC2)		 Saccharomyces cerevisiae
TI:4932 None
 
H3BNG1_HUMAN
Ensembl»
0.0
RAB3I protein Homo sapiens
TI:9606 None
 
Q20759_CAEEL
WormBase»
0.5
rabi-1 GDP/GTP exchange factor
Sec2 N-terminal domain-containing protein		 Caenorhabditis elegans
TI:6239 None
 
R3GEF_RAT
RGD»
3.1
Rab3il1 Guanine nucleotide exchange factor for Rab-3A (Rab-3A-interacting-like
protein 1) (Rab3A-interacting-like protein 1) (Rabin3-like 1)		 Rattus norvegicus
TI:10116 None
 
RAB3I_MOUSE
Ensembl»
6.4
Rab3ip Rab-3A-interacting protein (Rab3A-interacting
protein) (Rabin-3) (SSX2-interacting protein)		 Mus musculus
TI:10090 None
 
SEC2_SCHPO
PomBase»
2.8
sec2 Rab guanine nucleotide exchange factor
sec2 (GDP-GTP exchange factor sec2)		 Schizosaccharomyces pombe
TI:4896 None
 
SPO13_SCHPO
PomBase»
4.8
spo13 Sporulation-specific protein 13 Schizosaccharomyces pombe
TI:4896 None
 
A0A8M9PH17_DANRE
ZFIN»
0.5
rab3il1 Guanine nucleotide exchange factor
for Rab-3A isoform X1		 Danio rerio
TI:7955 None
   
A0A8V0YLA2_CHICK
Ensembl»
0.5
RAB3IP RAB3A interacting protein Gallus gallus
TI:9031 None
   
A0A8V1A7C2_CHICK
Ensembl»
0.5
RAB3IL1 RAB3A interacting protein like 1 Gallus gallus
TI:9031 None