Collated Gene Ontology terms

Biological process: guanyl-nucleotide exchange factor activity(2005, 2010, 2012, 2016, 2021, 2024, 2025) identical protein binding(2023, 2025) small GTPase binding(2023) GTPase binding(2005, 2025) phosphatidylinositol-4-phosphate binding(2013) kinase binding(2011, 2025)

Molecular function: protein transport2025 protein targeting to membrane2014, 2025 exocytosis2005, 2013, 2025 cilium assembly2008, 2025 negative regulation of filopodium assembly2016, 2025 ascospore-type prospore membrane formation2010, 2021, 2025 sporulation resulting in formation of a cellular spore2021, 2025 protein localization to meiotic spindle pole body2017, 2025 autophagy2013 ascospore-type prospore-specific spindle pole body remodeling2008, 2025
ascospore formation2008, 2025 meiotic cell cycle2025 intracellular protein transport2005 hyphal growth2014 filamentous growth2014 ciliary basal body-plasma membrane docking2025 Golgi to plasma membrane transport2008

Cellular component: cytosol2005, 2013, 2014, 2016, 2024, 2025 cell tip2009, 2020 nucleus2005, 2025 centrosome2024, 2025 nucleoplasm2024, 2025 meiotic spindle pole body2016, 2017, 2024, 2025 cytoplasm2006, 2025 cellular bud neck2013, 2018, 2025 Golgi to plasma membrane transport vesicle2014, 2025 transport vesicle2013, 2025
proximal dendrite2016, 2025 perinuclear region of cytoplasm2016, 2025 lamellipodium2025 cytoskeleton2025 cellular bud tip2013, 2025 vesicle2025 prospore membrane2016, 2025 meiotic spindle pole2017, 2025 medial cortical node2016, 2025 cytoplasmic vesicle2025 cell cortex of cell tip2016, 2025 spitzenkorper2014 spindle pole body2025 mating projection tip2018 ciliary basal body2008 cell division site2009

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 3/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 15/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
RAB3I_HUMAN
Ensembl»
7.3
RAB3IP Rab-3A-interacting protein (Rab3A-interacting protein)
(Rabin-3) (Rabin8) (SSX2-interacting protein)		 Homo sapiens
TI:9606 None
 
G3QZA3_GORGO
Ensembl»
0.0
RAB3IP RAB3A interacting protein Gorilla gorilla
TI:9593 None
 
G3R9L2_GORGO
Ensembl»
0.0
RAB3IL1 GDP/GTP exchange factor
Sec2 N-terminal domain-containing protein		 Gorilla gorilla
TI:9593 None
 
H2Q6G3_PANTR
Ensembl»
0.0
RAB3IP RAB3A interacting protein Pan troglodytes
TI:9598 None
 
RAB3I_RAT
RGD»
6.9
Rab3ip Rab-3A-interacting protein (Rab3A-interacting
protein) (Rabin-3) (SSX2-interacting protein)		 Rattus norvegicus
TI:10116 None
 
B7QK76_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW014818 Rabin, putative Ixodes scapularis
TI:6945 None
 
B7QK75_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW014817 Uncharacterized protein Ixodes scapularis
TI:6945 None
 
R3GEF_HUMAN
Ensembl»
3.0
RAB3IL1 Guanine nucleotide exchange factor for Rab-3A (Rab-3A-interacting-like
protein 1) (Rab3A-interacting-like protein 1) (Rabin3-like 1)		 Homo sapiens
TI:9606 None
 
R3GEF_MOUSE
Ensembl»
2.5
Rab3il1 Guanine nucleotide exchange factor for Rab-3A (Rab-3A-interacting-like
protein 1) (Rab3A-interacting-like protein 1) (Rabin3-like 1)		 Mus musculus
TI:10090 None
 
SEC2_YEAST
SGD»
7.7
SEC2 Rab guanine nucleotide exchange factor
SEC2 (GDP-GTP exchange factor SEC2)		 Saccharomyces cerevisiae
TI:4932 None
 
H3BNG1_HUMAN
Ensembl»
0.0
RAB3I protein Homo sapiens
TI:9606 None
 
T1FB94_HELRO
EnsemblMetazoa»
0.0
20206093 GDP/GTP exchange factor
Sec2 N-terminal domain-containing protein		 Helobdella robusta
TI:6412 None
 
A0A7U2EPL9_PHANO
TubercuList»
0.0
JI435_001720 GDP/GTP exchange factor
Sec2 N-terminal domain-containing protein		 Phaeosphaeria nodorum
TI:13684 None
 
A0A7U2FDL9_PHANO
TubercuList»
0.0
JI435_101130 GDP/GTP exchange factor
Sec2 N-terminal domain-containing protein		 Phaeosphaeria nodorum
TI:13684 None
 
A7EDG4_SCLS1
TubercuList»
0.0
SS1G_03354 GDP/GTP exchange factor
Sec2 N-terminal domain-containing protein		 Sclerotinia sclerotiorum
TI:5180 None
 
A7EFC4_SCLS1
TubercuList»
0.0
SS1G_04015 GDP/GTP exchange factor
Sec2 N-terminal domain-containing protein		 Sclerotinia sclerotiorum
TI:5180 None
 
A7SDC4_NEMVE
neXtProt»
0.0
NEMVEDRAFT_v1g233044 GDP/GTP exchange factor
Sec2 N-terminal domain-containing protein		 Nematostella vectensis
TI:45351 None
 
A8WNL5_CAEBR
WormBase»
0.0
CBG00556 CBG_00556 Protein CBG00556 Caenorhabditis briggsae
TI:6238 None
 
A9UNZ6_MONBE
neXtProt»
0.0
MONBRDRAFT_21913 GDP/GTP exchange factor
Sec2 N-terminal domain-containing protein		 Monosiga brevicollis
TI:81824 None
 
B3SC23_TRIAD
CTD»
0.0
TRIADDRAFT_61823 GDP/GTP exchange factor
Sec2 N-terminal domain-containing protein		 Trichoplax adhaerens
TI:10228 None
 
B6K2A0_SCHJY
TubercuList»
0.0
sec2 Guanyl-nucleotide exchange factor Sec2 Schizosaccharomyces japonicus
TI:4897 None
 
B6K2R3_SCHJY
TubercuList»
0.0
spo13 Sporulation specific protein Spo13 Schizosaccharomyces japonicus
TI:4897 None
 
D2A3H1_TRICA
neXtProt»
0.0
AUGUSTUS-3.0.2_07982 Guanine nucleotide exchange
factor for Rab-3A-like Protein		 Tribolium castaneum
TI:7070 None
 
E3KLL2_PUCGT
TubercuList»
0.0
PGTG_11356 GDP/GTP exchange factor
Sec2 N-terminal domain-containing protein		 Puccinia graminis
TI:5297 None
 
E9HNC8_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_302453 GDP/GTP exchange factor
Sec2 N-terminal domain-containing protein		 Daphnia pulex
TI:6669 None
 
F4NWC2_BATDJ
euHCVdb»
0.0
BATDEDRAFT_36635 Expressed protein Batrachochytrium dendrobatidis
TI:109871 None
 
F4P3A3_BATDJ
neXtProt»
0.0
BATDEDRAFT_88527 GDP/GTP exchange factor
Sec2 N-terminal domain-containing protein		 Batrachochytrium dendrobatidis
TI:109871 None
 
F6PJ75_CIOIN
Ensembl»
0.0
GDP/GTP exchange factor
Sec2 N-terminal domain-containing protein		 Ciona intestinalis
TI:7719 None
 
H2R5C8_PANTR
Ensembl»
0.0
RAB3IL1 RAB3A interacting protein like 1 Pan troglodytes
TI:9598 None
 
Q20759_CAEEL
WormBase»
0.5
rabi-1 GDP/GTP exchange factor
Sec2 N-terminal domain-containing protein		 Caenorhabditis elegans
TI:6239 None
 
Q28G01_XENTR
Xenbase»
0.0
rab3ip RAB3A interacting protein (Rabin3)
(Rab-3A-interacting protein isoform X1)		 Xenopus tropicalis
TI:8364 None
 
Q2KI32_BOVIN
Ensembl»
0.0
RAB3IP RAB3A interacting protein Bos taurus
TI:9913 None
 
Q4WZM8_ASPFU
TubercuList»
0.0
AFUA_2G16390 GDP/GTP exchange factor
Sec2 N-terminal domain-containing protein		 Aspergillus fumigatus
TI:746128 None
 
Q5AWH8_EMENI
TubercuList»
0.0
ANIA_07352 GDP/GTP exchange factor
Sec2 N-terminal domain-containing protein		 Emericella nidulans
TI:162425 None
 
Q5B3X1_EMENI
TubercuList»
0.0
ANIA_04759 GDP/GTP exchange factor
Sec2p, putative (AFU_orthologue AFUA_3G06430)		 Emericella nidulans
TI:162425 None
 
Q5KAR5_CRYD1
TubercuList»
0.0
CNJ00770 GDP/GTP exchange factor
Sec2 N-terminal domain-containing protein		 Cryptococcus deneoformans
TI:40410 None
 
Q5KK49_CRYD1
TubercuList»
0.0
CNC04260 GDP/GTP exchange factor
Sec2 N-terminal domain-containing protein		 Cryptococcus deneoformans
TI:40410 None
 
Q6C068_YARLI
TubercuList»
0.0
YALI0_F27379g YALI0F27379p Yarrowia lipolytica
TI:4952 None
 
Q6DDN1_XENLA
Xenbase»
0.0
rab3ip.S RAB3A interacting protein
S homeolog (Rab3ip-prov protein)		 Xenopus laevis
TI:8355 None
 
Q752A5_EREGS
euHCVdb»
0.0
AGOS_AFR670W AFR670Wp Eremothecium gossypii
TI:33169 None
 
Q7S7T9_NEUCR
TubercuList»
0.0
NCU04154 GDP/GTP exchange factor
Sec2 N-terminal domain-containing protein		 Neurospora crassa
TI:5141 None
 
Q7SH95_NEUCR
TubercuList»
0.0
NCU01911 GDP/GTP exchange factor Sec2p Neurospora crassa
TI:5141 None
 
R3GEF_BOVIN
CTD»
0.0
RAB3IL1 Guanine nucleotide exchange factor for Rab-3A (Rab-3A-interacting-like
protein 1) (Rab3A-interacting-like protein 1) (Rabin3-like 1)		 Bos taurus
TI:9913 None
 
R3GEF_RAT
RGD»
3.1
Rab3il1 Guanine nucleotide exchange factor for Rab-3A (Rab-3A-interacting-like
protein 1) (Rab3A-interacting-like protein 1) (Rabin3-like 1)		 Rattus norvegicus
TI:10116 None
 
RAB3I_MOUSE
Ensembl»
6.4
Rab3ip Rab-3A-interacting protein (Rab3A-interacting
protein) (Rabin-3) (SSX2-interacting protein)		 Mus musculus
TI:10090 None
 
SEC2_ASPFU
EnsemblFungi»
0.0
sec2 Rab guanine nucleotide exchange factor sec2 Aspergillus fumigatus
TI:746128 None
 
SEC2_CANAL
EnsemblFungi»
0.0
SEC2 Rab guanine nucleotide exchange factor
SEC2 (GDP-GTP exchange factor SEC2)		 Candida albicans
TI:5476 None
 
SEC2_SCHPO
PomBase»
2.8
sec2 Rab guanine nucleotide exchange factor
sec2 (GDP-GTP exchange factor sec2)		 Schizosaccharomyces pombe
TI:4896 None
 
SPO13_SCHPO
PomBase»
4.8
spo13 Sporulation-specific protein 13 Schizosaccharomyces pombe
TI:4896 None
 
W5MJB7_LEPOC
Ensembl»
0.0
Uncharacterized protein Lepisosteus oculatus
TI:7918 None
 
W5NH72_LEPOC
Ensembl»
0.0
RAB3A interacting protein (rabin3) Lepisosteus oculatus
TI:7918 None
 
A0A1L8GYJ5_XENLA
Xenbase»
0.0
rab3ip.L RAB3A interacting protein L homeolog isoform X1 Xenopus laevis
TI:8355 None
   
A0A287B6H7_PIG
Ensembl»
0.0
RAB3IL1 RAB3A interacting protein like 1 Sus scrofa
TI:9823 None
   
A0A2A6B3W0_PRIPA
EnsemblMetazoa»
0.0
WBGene00112902 Uncharacterized protein Pristionchus pacificus
TI:54126 None
   
A0A2A6BD97_PRIPA
EnsemblMetazoa»
0.0
WBGene00105328 Uncharacterized protein Pristionchus pacificus
TI:54126 None
   
A0A3B3IFD2_ORYLA
Ensembl»
0.0
RAB3IP RAB3A interacting protein (rabin3) Oryzias latipes
TI:8090 None
   
A0A5F5PXH9_HORSE
Ensembl»
0.0
RAB3IL1 RAB3A interacting protein like 1 Equus caballus
TI:9796 None
   
A0A5F8A8K5_MACMU
Ensembl»
0.0
RAB3IP RAB3A interacting protein Macaca mulatta
TI:9544 None
   
A0A5F8GBW1_MONDO
Ensembl»
0.0
RAB3IP RAB3A interacting protein Monodelphis domestica
TI:13616 None
   
A0A6I8NYT6_ORNAN
Ensembl»
0.0
RAB3IL1 RAB3A interacting protein like 1 Ornithorhynchus anatinus
TI:9258 None
   
A0A6I8PNY6_ORNAN
Ensembl»
0.0
RAB3IP RAB3A interacting protein Ornithorhynchus anatinus
TI:9258 None
   
A0A6I8QMY7_XENTR
Xenbase»
0.0
rab3il1 Guanine nucleotide exchange factor for Rab-3A
isoform X1 (RAB3A interacting protein (rabin3)-like 1)		 Xenopus tropicalis
TI:8364 None
   
A0A7M7RB04_STRPU
EnsemblMetazoa»
0.0
GDP/GTP exchange factor
Sec2 N-terminal domain-containing protein		 Strongylocentrotus purpuratus
TI:7668 None
   
A0A8I3RY93_CANLF
Ensembl»
0.0
RAB3IL1 RAB3A interacting protein like 1 Canis lupus
TI:9612 None
   
A0A8I3S0B6_CANLF
Ensembl»
0.0
RAB3IP RAB3A interacting protein Canis lupus
TI:9612 None
   
A0A8J0V0C7_XENLA
Xenbase»
0.0
rab3il1.L Guanine nucleotide exchange factor
for Rab-3A isoform X1		 Xenopus laevis
TI:8355 None
   
A0A8J1JEU6_XENTR
Xenbase»
0.0
LOC101732885 Guanine nucleotide exchange factor
for Rab-3A-like isoform X1		 Xenopus tropicalis
TI:8364 None
   
A0A8M9PH17_DANRE
ZFIN»
0.5
rab3il1 Guanine nucleotide exchange factor
for Rab-3A isoform X1		 Danio rerio
TI:7955 None
   
A0A8V0YLA2_CHICK
Ensembl»
0.5
RAB3IP RAB3A interacting protein Gallus gallus
TI:9031 None
   
A0A8V1A7C2_CHICK
Ensembl»
0.5
RAB3IL1 RAB3A interacting protein like 1 Gallus gallus
TI:9031 None
   
A0A9J7HQI8_BRAFL
neXtProt»
0.0
LOC118406349 Guanine nucleotide exchange
factor for Rab-3A-like		 Branchiostoma floridae
TI:7739 None
   
A0ABI7WZR5_FELCA
Ensembl»
0.0
RAB3IP GDP/GTP exchange factor
Sec2 N-terminal domain-containing protein		 Felis catus
TI:9685 None
   
A0ABI7ZVQ7_FELCA
Ensembl»
0.0
RAB3IL1 GDP/GTP exchange factor
Sec2 N-terminal domain-containing protein		 Felis catus
TI:9685 None
   
F1SH42_PIG
Ensembl»
0.0
RAB3IP RAB3A interacting protein Sus scrofa
TI:9823 None
   
F6S434_MACMU
Ensembl»
0.0
RAB3IL1 RAB3A interacting protein like 1 Macaca mulatta
TI:9544 None
   
H2LNS5_ORYLA
Ensembl»
0.0
RAB3IL1 RAB3A interacting protein like 1 Oryzias latipes
TI:8090 None
   
H9G9E5_ANOCA
Ensembl»
0.0
RAB3IP RAB3A interacting protein Anolis carolinensis
TI:28377 None
   
H9GPF3_ANOCA
Ensembl»
0.0
RAB3IL1 RAB3A interacting protein like 1 Anolis carolinensis
TI:28377 None