Collated Gene Ontology terms

Biological process: actin filament binding(2024, 2025) microtubule binding(2024, 2025) protein phosphatase 2A binding(2014, 2025) actin binding(2025) ATP hydrolysis activity(2025) ATP binding(2025) SH3 domain binding(2025)

Molecular function: protein localization to actin cytoskeleton2020, 2024 negative regulation of cilium assembly2024, 2025 stress fiber assembly2024, 2025 contractile ring contraction2024, 2025 regulation of synapse organization2021, 2025 regulation of protein complex stability2024, 2025 modification of postsynaptic structure2024, 2025 apical constriction2024, 2025 neural fold bending2012, 2025 protein dephosphorylation2014
ventricular septum development2012 protein secretion2024 proteasomal protein catabolic process2024 neuron migration2024 negative regulation of transporter activity2014 negative regulation of transmembrane transport2014 intracellular protein localization2024 hindgut development2024 gene expression2024 corpus callosum development2024 cerebral cortex development2024 artery development2012 regulation of modification of postsynaptic actin cytoskeleton2025 regulation of hippo signaling2024 positive regulation of neuron projection arborization2020 positive regulation of lamellipodium morphogenesis2020 positive regulation of Arp2/3 complex-mediated actin nucleation2020 actin filament bundle retrograde transport2020

Cellular component: actin cytoskeleton2010, 2024, 2025 glutamatergic synapse2021, 2024, 2025 centrosome2022, 2024, 2025 cytoplasm2012, 2025 stress fiber2020, 2024, 2025 FAR/SIN/STRIPAK complex2020, 2024, 2025 cell projection2025 dendritic spine2024, 2025 midbody2024, 2025 chromosome, centromeric region2024, 2025
cell cortex2025 spindle midzone2024, 2025 nucleus2006, 2025 ciliary basal body2024, 2025 actin filament2024, 2025 tight junction2024, 2025 CERF complex2024, 2025 postsynaptic actin cytoskeleton2024, 2025 lamellipodium2020, 2025 spindle2025 postsynapse2024, 2025 perikaryon2025 microtubule2025 membrane2014, 2025 dendrite2025 cytoskeleton2025 bicellular tight junction2025 synaptic vesicle2025 plasma membrane2025 nucleolus2025 extracellular exosome2014 cytosol2020

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 0/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
Q95QQ9_CAEEL
WormBase»
0.0
C49H3.6 CELE_C49H3.6 Cortactin-binding protein-2
N-terminal domain-containing protein		 Caenorhabditis elegans
TI:6239 None
 
A0A8N7UVR0_DANRE
ZFIN»
0.5
luzp1 Leucine zipper protein 1 Danio rerio
TI:7955 None
 
A0AB13AB69_DANRE
CTD»
0.0
filip1a Filamin A interacting protein 1a Danio rerio
TI:7955 None 		     
A0AB40E9R1_DANRE
ZFIN»
0.0
cttnbp2nlb CTTNBP2 N-terminal like b isoform 2 Danio rerio
TI:7955 None
   
F1Q9J8_DANRE
ZFIN»
0.5
cttnbp2nla CTTNBP2 N-terminal-like a
(CTTNBP2 N-terminal-like protein)		 Danio rerio
TI:7955 None
 
F1QFV1_DANRE
ZFIN»
0.5
cttnbp2 Cortactin-binding protein 2 Danio rerio
TI:7955 None
 
FIL1L_DANRE
ZFIN»
0.5
filip1l Filamin A-interacting protein 1-like Danio rerio
TI:7955 None
 
CT2NL_DROME
FlyBase»
5.1
Naus CTTNBP2 N-terminal-like
protein (Protein Nausicaa)		 Drosophila melanogaster
TI:7227 None
 
A0A8V0XMV6_CHICK
Ensembl»
0.5
FILIP1 Filamin A interacting protein 1 Gallus gallus
TI:9031 None
   
A0A8V0XPR3_CHICK
Ensembl»
0.0
FILIP1L Filamin A interacting protein 1 like Gallus gallus
TI:9031 None 		     
A0A8V0YPS1_CHICK
Ensembl»
0.5
LUZP1 Leucine zipper protein 1 Gallus gallus
TI:9031 None
   
A0A8V1A3G3_CHICK
Ensembl»
0.0
CTTNBP2NL CTTNBP2 N-terminal like Gallus gallus
TI:9031 None
   
A0M8U5_CHICK
Ensembl»
0.5
CORTBP2 Cortactin-binding protein 2 Gallus gallus
TI:9031 None
 
CT2NL_HUMAN
Ensembl»
3.7
CTTNBP2NL CTTNBP2 N-terminal-like protein Homo sapiens
TI:9606 None
 
CTTB2_HUMAN
Ensembl»
0.5
CTTNBP2 Cortactin-binding protein 2 (CortBP2) Homo sapiens
TI:9606 None
 
FIL1L_HUMAN
Ensembl»
0.5
FILIP1L Filamin A-interacting protein 1-like (130 kDa GPBP-interacting protein) (90
kDa GPBP-interacting protein) (Protein down-regulated in ovarian cancer 1) (DOC-1)		 Homo sapiens
TI:9606 None
 
FLIP1_HUMAN
Ensembl»
0.5
FILIP1 Filamin-A-interacting protein 1 (FILIP) Homo sapiens
TI:9606 None
 
LUZP1_HUMAN
Ensembl»
5.2
LUZP1 Leucine zipper protein 1 (Filamin
mechanobinding actin cross-linking protein) (Fimbacin)		 Homo sapiens
TI:9606 None
 
CT2NL_MOUSE
Ensembl»
3.3
Cttnbp2nl CTTNBP2 N-terminal-like protein Mus musculus
TI:10090 None
 
FIL1L_MOUSE
Ensembl»
4.5
Filip1l Filamin A-interacting protein 1-like (Protein down-regulated
in ovarian cancer 1 homolog) (DOC-1)		 Mus musculus
TI:10090 None
 
FLIP1_MOUSE
Ensembl»
4.5
Filip1 Filamin-A-interacting protein 1 (FILIP) Mus musculus
TI:10090 None
 
LUZP1_MOUSE
Ensembl»
10.1
Luzp1 Leucine zipper protein 1 (Filamin mechanobinding actin
cross-linking protein) (Fimbacin) (Leucine zipper motif-containing protein)		 Mus musculus
TI:10090 None
 
D4A8X8_RAT
RGD»
0.5
Cttnbp2nl CTTNBP2 N-terminal like Rattus norvegicus
TI:10116 None
   
D4A900_RAT
RGD»
3.0
Filip1l Filamin A interacting protein 1-like Rattus norvegicus
TI:10116 None
   
FLIP1_RAT
RGD»
2.5
Filip1 Filamin-A-interacting protein 1 (FILIP) Rattus norvegicus
TI:10116 None
 
LUZP1_RAT
RGD»
9.0
Luzp1 Leucine zipper protein 1 (Filamin mechanobinding actin
cross-linking protein) (Fimbacin) (Leucine zipper motif-containing protein)		 Rattus norvegicus
TI:10116 None