Collated Gene Ontology terms

Biological process: phosphatidylinositol-3,4,5-trisphosphate binding(2021, 2025) calcium ion binding(2025)

Molecular function: autophagy of mitochondrion2012, 2024, 2025 autophagy2025 DNA-templated transcription2025 response to hypoxia2012, 2025 mitophagy2019, 2024, 2025 intracellular triglyceride homeostasis2021, 2025 mitochondrial fusion2024, 2025 regulation of platelet activation2021 phospholipid homeostasis2016 mitochondrion organization2016

Cellular component: mitochondrial outer membrane2012, 2015, 2017, 2018, 2022, 2024, 2025 membrane2025 nucleus2014, 2025 mitochondrion2009, 2010, 2014, 2017, 2018, 2021, 2024, 2025

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 4/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 11/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 1/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 1/39 
Archea: 0/8 
Bacteria: 1/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
A0A0G2JX60_RAT
RGD»
0.5
Fundc2b FUN14 domain containing 2B Rattus norvegicus
TI:10116 None
   
A0A1D5PY21_CHICK
Ensembl»
0.5
FUNDC2 FUN14 domain-containing protein 2 (Hepatitis
C virus core-binding protein 6)		 Gallus gallus
TI:9031 None
   
A0A1D5QXT5_MACMU
Ensembl»
0.0
FUN14 domain-containing protein 2 Macaca mulatta
TI:9544 None
   
A0A1S4GYG0_ANOGA
EnsemblMetazoa»
0.0
Uncharacterized protein Anopheles gambiae
TI:7165 None
 
A0A2I2YIE7_GORGO
Ensembl»
0.0
FUNDC1 FUN14 domain containing 1 Gorilla gorilla
TI:9593 None
 
A0A2I2ZER9_GORGO
Ensembl»
0.0
FUNDC2 FUN14 domain-containing protein 2 (Hepatitis
C virus core-binding protein 6)		 Gorilla gorilla
TI:9593 None
 
A0A2I2ZR04_GORGO
Ensembl»
0.0
FUN14 domain containing 1 Gorilla gorilla
TI:9593 None
 
A0A2I3RCS9_PANTR
Ensembl»
0.0
FUNDC1 Pan troglodytes
TI:9598 None
 
A0A2I3RQD0_PANTR
Ensembl»
0.0
FUN14 domain containing 2 Pan troglodytes
TI:9598 None
 
A0A2I3TR91_PANTR
Ensembl»
0.0
FUN14 domain containing 1 Pan troglodytes
TI:9598 None
   
A0A3B3IHJ9_ORYLA
Ensembl»
0.0
FUNDC1 FUN14 domain containing 1 Oryzias latipes
TI:8090 None
   
A0A3Q1LWN7_BOVIN
Ensembl»
0.0
FUN14 domain containing 1 Bos taurus
TI:9913 None
   
A0A3Q1LZ17_BOVIN
Ensembl»
0.0
LOC107132671 FUN14 domain-containing protein 1 Bos taurus
TI:9913 None
   
A0A5F8GW77_MONDO
Ensembl»
0.0
FUN14 domain-containing protein 2 (Hepatitis
C virus core-binding protein 6)		 Monodelphis domestica
TI:13616 None
   
A0A5F8H9F6_MONDO
Ensembl»
0.0
FUNDC1 FUN14 domain containing 1 Monodelphis domestica
TI:13616 None
   
A0A6I8NW86_ORNAN
Ensembl»
0.0
FUNDC2 FUN14 domain-containing protein 2 (Hepatitis
C virus core-binding protein 6)		 Ornithorhynchus anatinus
TI:9258 None
   
A0A7M7NL48_STRPU
EnsemblMetazoa»
0.0
FUN14 domain-containing protein 1 Strongylocentrotus purpuratus
TI:7668 None
   
A0A7U2F8N7_PHANO
TubercuList»
0.0
JI435_093280 Uncharacterized protein Phaeosphaeria nodorum
TI:13684 None
 
A0A803TBF0_ANOCA
Ensembl»
0.0
Uncharacterized protein Anolis carolinensis
TI:28377 None
   
A0A803TNZ4_ANOCA
Ensembl»
0.0
fundc1 FUN14 domain containing 1 Anolis carolinensis
TI:28377 None
   
A0A8I3S6M5_CANLF
Ensembl»
0.0
FUNDC1 FUN14 domain containing 1 Canis lupus
TI:9612 None
   
A0A8R1Y4H5_PRIPA
EnsemblMetazoa»
0.0
WBGene00089727 Uncharacterized protein Pristionchus pacificus
TI:54126 None
   
A0A9J7M3W1_BRAFL
euHCVdb»
0.0
LOC118428216 FUN14 domain-containing protein 1-like Branchiostoma floridae
TI:7739 None
   
A0ABI7VTB5_FELCA
Ensembl»
0.0
FUNDC2 FUN14 domain-containing protein 2 (Hepatitis
C virus core-binding protein 6)		 Felis catus
TI:9685 None
   
A0ABI7VTZ4_FELCA
Ensembl»
0.0
FUNDC1 FUN14 domain containing 1 Felis catus
TI:9685 None
   
A0ABI7XRW6_FELCA
Ensembl»
0.0
FUN14 domain containing 1 Felis catus
TI:9685 None
   
A0ABK0L7N0_RAT
RGD»
1.5
Fundc2 FUN14 domain-containing protein 2 (Hepatitis
C virus core-binding protein 6)		 Rattus norvegicus
TI:10116 None
   
A7SUB5_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g247457 FUN14 domain-containing protein 1 Nematostella vectensis
TI:45351 None
 
A8IPT6_CHLRE
euHCVdb»
0.0
CHLRE_17g704600v5 EF-hand domain-containing protein Chlamydomonas reinhardtii
TI:3055 None
 
A8WT57_CAEBR
WormBase»
0.0
fndc-1 Protein CBG02943 Caenorhabditis briggsae
TI:6238 None
 
A9V929_MONBE
euHCVdb»
0.0
MONBRDRAFT_28749 EF-hand domain-containing protein Monosiga brevicollis
TI:81824 None
 
B3S8D7_TRIAD
CTD»
0.0
TRIADDRAFT_60503 FUN14 domain-containing protein 1 Trichoplax adhaerens
TI:10228 None
 
B8BWF9_THAPS
euHCVdb»
0.0
THAPSDRAFT_3956 Uncharacterized protein Thalassiosira pseudonana
TI:35128 None
 
B8C4W1_THAPS
euHCVdb»
0.0
THAPSDRAFT_5865 EF-hand domain-containing protein Thalassiosira pseudonana
TI:35128 None
 
D6W785_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_14240 FUN14 domain-containing protein 1-like Protein Tribolium castaneum
TI:7070 None
 
D6WD77_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_00806 FUN14 domain-containing protein 1B-like Protein Tribolium castaneum
TI:7070 None
 
E3KIZ0_PUCGT
TubercuList»
0.0
PGTG_10643 Uncharacterized protein Puccinia graminis
TI:5297 None
 
E3KTU8_PUCGT
TubercuList»
0.0
PGTG_13558 Uncharacterized protein Puccinia graminis
TI:5297 None
 
E3KY39_PUCGT
TubercuList»
0.0
PGTG_15081 FUN14 domain-containing protein 1 Puccinia graminis
TI:5297 None
 
E9HCY2_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_93478 FUN14 domain-containing protein 1 Daphnia pulex
TI:6669 None
 
F0ZZ80_DICPU
TubercuList»
0.0
DICPUDRAFT_92918 FUN14 family protein Dictyostelium purpureum
TI:5786 None
 
F1RWZ9_PIG
Ensembl»
0.0
FUNDC1 FUN14 domain containing 1 Sus scrofa
TI:9823 None
   
F4NSR4_BATDJ
euHCVdb»
0.0
BATDEDRAFT_22171 FUN14 family protein Batrachochytrium dendrobatidis
TI:109871 None
 
F6Q6K5_ORNAN
Ensembl»
0.0
FUNDC1 FUN14 domain containing 1 Ornithorhynchus anatinus
TI:9258 None
   
F6RA93_HORSE
Ensembl»
0.0
FUNDC2 FUN14 domain-containing protein 2 (Hepatitis
C virus core-binding protein 6)		 Equus caballus
TI:9796 None
   
F7E3C0_MACMU
Ensembl»
0.0
FUNDC1 FUN14 domain containing 1
(FUN14 domain-containing protein 1)		 Macaca mulatta
TI:9544 None
 
F7EH14_MACMU
Ensembl»
0.0
FUNDC1 FUN14 domain containing 1
(FUN14 domain-containing protein 1)		 Macaca mulatta
TI:9544 None
 
FNDC1_CAEEL
WormBase»
1.3
fndc-1 FUN14 domain-containing protein fndc-1 Caenorhabditis elegans
TI:6239 None
 
FUD1A_XENLA
Xenbase»
0.0
fundc1-a FUN14 domain-containing protein 1A Xenopus laevis
TI:8355 None
 
FUD1B_XENLA
AG»
0.0
fundc1-b FUN14 domain-containing protein 1B Xenopus laevis
TI:8355 None
 
FUN14_YEAST
SGD»
2.1
FUN14 Protein FUN14 Saccharomyces cerevisiae
TI:4932 None
 
FUND1_BOVIN
Ensembl»
0.0
FUNDC1 FUN14 domain-containing protein 1 Bos taurus
TI:9913 None
 
FUND1_CHICK
CTD»
1.5
FUNDC1 FUN14 domain-containing protein 1 Gallus gallus
TI:9031 None
 
FUND1_DANRE
ZFIN»
1.5
fundc1 FUN14 domain-containing protein 1 Danio rerio
TI:7955 None
 
FUND1_HUMAN
Ensembl»
6.1
FUNDC1 FUN14 domain-containing protein 1 Homo sapiens
TI:9606 None
 
FUND1_MOUSE
Ensembl»
3.5
Fundc1 FUN14 domain-containing protein 1 Mus musculus
TI:10090 None
 
FUND1_RAT
RGD»
3.5
Fundc1 FUN14 domain-containing protein 1 Rattus norvegicus
TI:10116 None
 
FUND1_XENTR
Xenbase»
0.0
fundc1 FUN14 domain-containing protein 1 Xenopus tropicalis
TI:8364 None
 
FUND2_BOVIN
Ensembl»
0.0
FUNDC2 FUN14 domain-containing protein 2 (Hepatitis
C virus core-binding protein 6)		 Bos taurus
TI:9913 None
 
FUND2_HUMAN
Ensembl»
2.6
FUNDC2 FUN14 domain-containing protein 2 (Cervical cancer proto-oncogene 3
protein) (HCC-3) (Hepatitis C virus core-binding protein 6)		 Homo sapiens
TI:9606 None
 
FUND2_MACMU
CTD»
0.0
FUNDC2 FUN14 domain-containing protein 2 (Hepatitis
C virus core-binding protein 6)		 Macaca mulatta
TI:9544 None
 
FUND2_MOUSE
Ensembl»
3.3
Fundc2 FUN14 domain-containing protein 2 (Hepatitis
C virus core-binding protein 6)		 Mus musculus
TI:10090 None
 
FUND2_PIG
Ensembl»
0.0
FUNDC2 FUN14 domain-containing protein 2 (Hepatitis
C virus core-binding protein 6)		 Sus scrofa
TI:9823 None
 
G3RFF3_GORGO
Ensembl»
0.0
FUN14 domain containing 2 Gorilla gorilla
TI:9593 None
 
H2MF74_ORYLA
Ensembl»
0.0
fundc1 FUN14 domain-containing protein 2 (Hepatitis
C virus core-binding protein 6)		 Oryzias latipes
TI:8090 None
   
H2R4R7_PANTR
Ensembl»
0.0
FUNDC1 FUN14 domain containing 1 Pan troglodytes
TI:9598 None
 
H2RFF5_PANTR
Ensembl»
0.0
FUNDC2 FUN14 domain-containing protein 2 (Hepatitis
C virus core-binding protein 6)		 Pan troglodytes
TI:9598 None
 
H2XYG4_CIOIN
Ensembl»
0.0
LOC100177927 FUN14 domain-containing protein 1B-like Ciona intestinalis
TI:7719 None
   
H3GCB0_PHYRM
EnsemblProtists»
0.0
EF-hand domain-containing protein Phytophthora ramorum
TI:164328 None
 
H3GDQ5_PHYRM
EnsemblProtists»
0.0
EF-hand domain-containing protein Phytophthora ramorum
TI:164328 None
 
H9FYR9_MACMU
Ensembl»
0.0
FUNDC2 FUN14 domain-containing protein 2 (Hepatitis
C virus core-binding protein 6)		 Macaca mulatta
TI:9544 None
 
H9G3U9_ANOCA
Ensembl»
0.0
FUN14 domain-containing protein 2 (Hepatitis
C virus core-binding protein 6)		 Anolis carolinensis
TI:28377 None
   
Q4WUD8_ASPFU
TubercuList»
0.0
AFUA_5G08100 FUN14 family protein Aspergillus fumigatus
TI:746128 None
 
Q586B6_TRYB2
TubercuList»
0.0
Tb06.4F7.90 FUN14 family Trypanosoma brucei
TI:5691 None
 
Q5APK1_CANAL
CGD»
0.0
CAALFM_C109060CA orf19.12227 Fun14p Candida albicans
TI:5476 None
 
Q5AVF6_EMENI
TubercuList»
0.0
ANIA_07724 Uncharacterized protein Emericella nidulans
TI:162425 None
 
Q5XJ60_DANRE
ZFIN»
0.0
fundc2 FUN14 domain-containing protein 2 (Hepatitis
C virus core-binding protein 6)		 Danio rerio
TI:7955 None
 
Q6CI94_YARLI
TubercuList»
0.0
YALI0_A00440g YALI0A00440p Yarrowia lipolytica
TI:4952 None
 
Q75K07_DICDI
dictyBase»
0.0
DDB_G0277699 Transmembrane protein Dictyostelium discoideum
TI:44689 None
 
Q7RYL7_NEUCR
TubercuList»
0.0
NCU00111 Uncharacterized protein Neurospora crassa
TI:5141 None
 
Q9D9Q3_MOUSE
Ensembl»
1.5
Fundc2b FUN14 domain containing 2B Mus musculus
TI:10090 None
 
Q9RXW2_DEIRA
EnsemblBacteria»
0.0
DR_0193 FUN14 family protein Deinococcus radiodurans
TI:1299 None
 
Q9VL16_DROME
FlyBase»
2.6
Fundc1 RE45833p Drosophila melanogaster
TI:7227 None
 
Q9VMN4_DROME
FlyBase»
0.5
Dmel\CG12511 Uncharacterized protein, isoform B Drosophila melanogaster
TI:7227 None
 
R4GMF5_CHICK
Ensembl»
0.5
FUNDC1 FUN14 domain containing 1 Gallus gallus
TI:9031 None
   
T1EKQ8_HELRO
EnsemblMetazoa»
0.0
20197158 FUN14 domain-containing protein Helobdella robusta
TI:6412 None
 
T1F367_HELRO
EnsemblMetazoa»
0.0
20203266 FUN14 domain-containing protein Helobdella robusta
TI:6412 None
 
W5M1H0_LEPOC
Ensembl»
0.0
FUN14 domain containing 1 Lepisosteus oculatus
TI:7918 None
 
W5N8P9_LEPOC
Ensembl»
0.0
FUN14 domain-containing protein 2 (Hepatitis
C virus core-binding protein 6)		 Lepisosteus oculatus
TI:7918 None
 
YDPH_SCHPO
PomBase»
0.5
SPAC29A4.17c Uncharacterized protein C29A4.17c Schizosaccharomyces pombe
TI:4896 None