Collated Gene Ontology terms

Biological process: metal ion binding(2025) cytochrome-c oxidase activity(2003, 2005, 2006, 2008, 2013, 2023, 2025) oxidoreductase activity(2025) electron transfer activity(2006)

Molecular function: mitochondrial electron transport, cytochrome c to oxygen2010, 2021, 2024, 2025 oxidative phosphorylation2024 proton transmembrane transport2025 cellular respiration2025 spinal cord motor neuron differentiation2008 embryonic organ development2008 positive regulation of cell cycle2008

Cellular component: respiratory chain complex IV2013, 2019, 2021, 2023, 2024, 2025 mitochondrial inner membrane2005, 2006, 2013, 2017, 2024, 2025 mitochondrion2006, 2009, 2013, 2014, 2018, 2021, 2024, 2025 mitochondrial membrane2025 plasma membrane2014 myelin sheath2014 mitochondrial intermembrane space2024

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 15/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
A0A8V0ZU95_CHICK
Ensembl»
0.5
COX5A Cytochrome c oxidase subunit 5A,
mitochondrial (Cytochrome c oxidase polypeptide Va)		 Gallus gallus
TI:9031 None
   
COX5A_DROME
FlyBase»
3.4
COX5A Cytochrome c oxidase subunit 5A,
mitochondrial (Cytochrome c oxidase polypeptide Va)		 Drosophila melanogaster
TI:7227 None
 
COX5A_HUMAN
Ensembl»
3.5
COX5A Cytochrome c oxidase subunit 5A,
mitochondrial (Cytochrome c oxidase polypeptide Va)		 Homo sapiens
TI:9606 None
 
COX6_YEAST
SGD»
2.9
COX6 Cytochrome c oxidase subunit 6,
mitochondrial (Cytochrome c oxidase polypeptide VI)		 Saccharomyces cerevisiae
TI:4932 None
 
COX5A_MOUSE
Ensembl»
1.0
Cox5a Cytochrome c oxidase subunit 5A,
mitochondrial (Cytochrome c oxidase polypeptide Va)		 Mus musculus
TI:10090 None
 
COX5A_RAT
RGD»
2.2
Cox5a Cytochrome c oxidase subunit 5A,
mitochondrial (Cytochrome c oxidase polypeptide Va)		 Rattus norvegicus
TI:10116 None
 
COX5A_CAEEL
WormBase»
1.3
cox-5A Cytochrome c oxidase subunit 5A,
mitochondrial (Cytochrome c oxidase polypeptide Va)		 Caenorhabditis elegans
TI:6239 None
 
Q4VBU7_DANRE
ZFIN»
2.9
cox5aa Cytochrome c oxidase subunit 5A,
mitochondrial (Cytochrome c oxidase polypeptide Va)		 Danio rerio
TI:7955 None
 
A0A0R4IVC8_DANRE
ZFIN»
2.9
cox5ab Cytochrome c oxidase subunit 5A,
mitochondrial (Cytochrome c oxidase polypeptide Va)		 Danio rerio
TI:7955 None
 
COX6_SCHPO
PomBase»
2.5
cox6 Cytochrome c oxidase subunit 6,
mitochondrial (Cytochrome c oxidase polypeptide VI)		 Schizosaccharomyces pombe
TI:4896 None