Cluster UKP07991
- MODULATOR OF SMOOTHENED PROTEIN
Standard knownness: 9.6; Custom knownness: None; Num. species: 30; Orthology database: Panther19.0; Protein members: 37
Collated Gene Ontology terms
Molecular function:
negative regulation of smoothened signaling pathway2018, 2019, 2024
regulation of protein stability2018, 2024
regulation of neuron differentiation2018, 2024
smoothened signaling pathway2024
protein localization2024
lung development2024
left/right pattern formation2024
in utero embryonic development2024
heart development2024
gene expression2024
embryonic skeletal system development2024
embryonic limb morphogenesis2024
cell differentiation2024
cranial skeletal system development2023
Cellular component: ciliary membrane2018, 2019, 2024 Golgi apparatus2018, 2019, 2024 membrane2024 plasma membrane2018, 2024 cell projection2024
Phylogenetic distribution
| Chordates: | 21/21 |  |
| Echinoderms: | 0/0 | |
| Hemichordates: | 1/1 | |
| Annelids: | 1/1 | |
| Molluscs: | 0/0 | |
| Bryozoans: | 0/0 | |
| Platyhelminthes: | 0/0 | |
| Rotifers: | 0/0 | |
| Nematodes: | 0/3 | |
| Arthropods: | 5/5 | |
| Tardigrades: | 0/0 | |
| Placozoa: | 0/1 | |
| Cnidaria: | 1/1 | |
| Porifera: | 0/0 | |
| Choanoflagellates+: | 1/1 | |
| Dikarya: | 0/14 | |
| Fungi (other): | 0/1 | |
| Protozoa: | 0/3 | |
| Excavates: | 0/4 | |
| Harosa: | 0/4 | |
| Hacrobia: | 0/0 | |
| Plants: | 0/39 | |
| Archea: | 0/8 | |
| Bacteria: | 0/35 |
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Proteins
| UniProt ID Organism DB» |
Standard knownness | clustom knownness | Gene name | Description | Species [Key only] | GO terms | Seq. links | Protein domain links | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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A0A2I2YD15_GORGO Ensembl» |
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Modulator of smoothened |
Gorilla gorilla TI:9593 None |
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A0A2I2ZL45_GORGO Ensembl» |
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Modulator of smoothened |
Gorilla gorilla TI:9593 None |
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A0A7M7HJH4_STRPU EnsemblMetazoa» |
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Uncharacterized protein |
Strongylocentrotus purpuratus TI:7668 None |
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A0A7M7NS48_STRPU EnsemblMetazoa» |
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Modulator of smoothened protein |
Strongylocentrotus purpuratus TI:7668 None |
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H2XLC8_CIOIN Ensembl» |
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Uncharacterized protein |
Ciona intestinalis TI:7719 None |
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W5MNK1_LEPOC Ensembl» |
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Modulator of smoothened |
Lepisosteus oculatus TI:7918 None |
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Q7QNF4_ANOGA EnsemblMetazoa» |
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1268296 | AGAP012554-PA |
Anopheles gambiae TI:7165 None |
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Q7Q020_ANOGA EnsemblMetazoa» |
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1280479 | AGAP012207-PA |
Anopheles gambiae TI:7165 None |
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T1F994_HELRO EnsemblMetazoa» |
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20205393 | Uncharacterized protein |
Helobdella robusta TI:6412 None |
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B7PZ75_IXOSC EnsemblMetazoa» |
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8033543 | Uncharacterized protein |
Ixodes scapularis TI:6945 None |
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D6WF05_TRICA EnsemblMetazoa» |
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AUGUSTUS-3.0.2_03319 | Uncharacterized protein C16orf52 homolog A-like Protein |
Tribolium castaneum TI:7070 None |
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A0A8V0Z3N5_CHICK Ensembl» |
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C16orf52 | Modulator of smoothened |
Gallus gallus TI:9031 None |
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E9FW33_DAPPU EnsemblMetazoa» |
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DAPPUDRAFT_230240 | Uncharacterized protein |
Daphnia pulex TI:6669 None |
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Q9VW61_DROME FlyBase» |
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Dmel\CG14182 | MIP13743p (Uncharacterized protein, isoform A) (Uncharacterized protein, isoform B) (Uncharacterized protein, isoform D) |
Drosophila melanogaster TI:7227 None |
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A0A3B3HE63_ORYLA Ensembl» |
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LOC101154810 | Modulator of smoothened |
Oryzias latipes TI:8090 None |
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A0A3Q2I9R5_HORSE Ensembl» |
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LOC111769919 | Modulator of smoothened |
Equus caballus TI:9796 None |
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C3Y9L6_BRAFL CTD» |
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LOC118408743 | Uncharacterized protein C16orf52 homolog A-like |
Branchiostoma floridae TI:7739 None |
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A9UW96_MONBE EnsemblProtists» |
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MONBRDRAFT_36587 | Uncharacterized protein |
Monosiga brevicollis TI:81824 None |
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A0A287ABX3_PIG Ensembl» |
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MOSMO | Modulator of smoothened |
Sus scrofa TI:9823 None |
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A0A5F8GTC5_MONDO Ensembl» |
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MOSMO | Modulator of smoothened |
Monodelphis domestica TI:13616 None |
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A0A8I3RQY7_CANLF Ensembl» |
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MOSMO | Modulator of smoothened |
Canis lupus TI:9612 None |
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F6RRH1_ORNAN Ensembl» |
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MOSMO | Modulator of smoothened |
Ornithorhynchus anatinus TI:9258 None |
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F7DBW4_HORSE Ensembl» |
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MOSMO | Modulator of smoothened |
Equus caballus TI:9796 None |
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H2LXI0_ORYLA Ensembl» |
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MOSMO | Modulator of smoothened |
Oryzias latipes TI:8090 None |
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H9GKJ6_ANOCA Ensembl» |
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MOSMO | Modulator of smoothened |
Anolis carolinensis TI:28377 None |
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I0FKB6_MACMU Ensembl» |
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MOSMO | Modulator of smoothened |
Macaca mulatta TI:9544 None |
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K7CDE3_PANTR Ensembl» |
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MOSMO | Chromosome 16 open reading frame 52 (Modulator of smoothened) |
Pan troglodytes TI:9598 None |
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M3WY53_FELCA Ensembl» |
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MOSMO | Modulator of smoothened |
Felis catus TI:9685 None |
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MOSMO_HUMAN Ensembl» |
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MOSMO | Modulator of smoothened protein (Attenuator of hedgehog) |
Homo sapiens TI:9606 None |
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A0A8I6A5P2_RAT RGD» |
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Mosmo | Modulator of smoothened |
Rattus norvegicus TI:10116 None |
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MOSMO_MOUSE Ensembl» |
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Mosmo | Modulator of smoothened protein (Attenuator of hedgehog) |
Mus musculus TI:10090 None |
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A7SLD0_NEMVE EnsemblMetazoa» |
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NEMVEDRAFT_v1g214064 | Uncharacterized protein |
Nematostella vectensis TI:45351 None |
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A7SLC9_NEMVE EnsemblMetazoa» |
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NEMVEDRAFT_v1g235646 | Modulator of smoothened protein |
Nematostella vectensis TI:45351 None |
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B0BM66_XENTR Xenbase» |
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mosmo | LOC100144972 protein (Modulator of smoothened) (Uncharacterized protein C16orf52 homolog) |
Xenopus tropicalis TI:8364 None |
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A0A8J1LRR8_XENLA Xenbase» |
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mosmo.L | Uncharacterized protein C16orf52 homolog B isoform X1 |
Xenopus laevis TI:8355 None |
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F1QJW0_DANRE Ensembl» |
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mosmoa | Modulator of smoothened a (Uncharacterized protein C16orf52 homolog B) |
Danio rerio TI:7955 None |
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MOSMO_DANRE ZFIN» |
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mosmob | Modulator of smoothened protein (Attenuator of hedgehog) |
Danio rerio TI:7955 None |
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