Standard knownness: 4.7; Custom knownness: None; Num. species: 34; Orthology database: Panther19.0; Protein members: 69
Molecular function: protein insertion into ER membrane2016, 2021, 2024 SRP-dependent cotranslational protein targeting to membrane, translocation2015, 2024 protein transport2024 response to unfolded protein2021, 2024 cotranslational protein targeting to membrane2003, 2021, 2024 collagen biosynthetic process2009, 2024 determination of heart left/right asymmetry2020, 2024 sphingolipid metabolic process2024 ceramide biosynthetic process2024
Cellular component: membrane2003, 2024 endoplasmic reticulum membrane2010, 2018, 2021, 2024 endoplasmic reticulum2003, 2015, 2024 rough endoplasmic reticulum2013 periciliary membrane compartment2014 dendrite terminus2015
| Chordates: | 22/21 |  | 
| Echinoderms: | 0/0 | |
| Hemichordates: | 1/1 | |
| Annelids: | 1/1 | |
| Molluscs: | 0/0 | |
| Bryozoans: | 0/0 | |
| Platyhelminthes: | 0/0 | |
| Rotifers: | 0/0 | |
| Nematodes: | 3/3 | |
| Arthropods: | 5/5 | |
| Tardigrades: | 0/0 | |
| Placozoa: | 1/1 | |
| Cnidaria: | 1/1 | |
| Porifera: | 0/0 | |
| Choanoflagellates+: | 0/1 | |
| Dikarya: | 0/14 | |
| Fungi (other): | 0/1 | |
| Protozoa: | 0/3 | |
| Excavates: | 0/4 | |
| Harosa: | 0/4 | |
| Hacrobia: | 0/0 | |
| Plants: | 0/39 | |
| Archea: | 0/8 | |
| Bacteria: | 0/35 | 
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| UniProt ID Organism DB» | Standard knownness | clustom knownness | Gene name | Description | Species [Key only] | GO terms | Seq. links | Protein domain links | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A0A803U1L2_ANOCA Ensembl» | 
 | 
 | LOC100563926 | Translocating chain-associated membrane protein | Anolis carolinensis TI:28377 None |  |  | ||||||
| G1KDK7_ANOCA Ensembl» | 
 | 
 | TRAM2 | Translocating chain-associated membrane protein | Anolis carolinensis TI:28377 None |  |  | ||||||
| G1KQI6_ANOCA Ensembl» | 
 | 
 | tram1 | Translocating chain-associated membrane protein | Anolis carolinensis TI:28377 None |  |  | ||||||
| Q7QDS0_ANOGA EnsemblMetazoa» | 
 | 
 | 1272659 | AGAP010386-PA | Anopheles gambiae TI:7165 None |  |  |  | |||||
| E1BCM2_BOVIN Ensembl» | 
 | 
 | TRAM2 | Translocating chain-associated membrane protein | Bos taurus TI:9913 None |  |  | ||||||
| TRAM1_BOVIN Ensembl» | 
 | 
 | TRAM1 | Translocating chain-associated membrane protein 1 (Protein TRAM1) | Bos taurus TI:9913 None |  |  |  | |||||
| A0A9J7HIK3_BRAFL CTD» | 
 | 
 | LOC118404847 | Translocating chain-associated membrane protein 1-like isoform X1 | Branchiostoma floridae TI:7739 None |  |  | ||||||
| A8WUY1_CAEBR WormBase» | 
 | 
 | tram-1 | Translocating chain-associated membrane protein | Caenorhabditis briggsae TI:6238 None |  |  |  | |||||
| Q9XXK7_CAEEL WormBase» | 
 | 
 | tram-1 | Translocating chain-associated membrane protein | Caenorhabditis elegans TI:6239 None |  |  |  | |||||
| A0A8I3N8J0_CANLF Ensembl» | 
 | 
 | TRAM2 | Translocation associated membrane protein 2 | Canis lupus TI:9612 None |  |  | ||||||
| A0A8I3S761_CANLF Ensembl» | 
 | 
 | TRAM1L1 | Translocation associated membrane protein 1 like 1 | Canis lupus TI:9612 None |  |  | ||||||
| TRAM1_CANLF Ensembl» | 
 | 
 | TRAM1 | Translocating chain-associated membrane protein 1 (Protein TRAM1) | Canis lupus TI:9612 None |  |  |  | |||||
| Q68A32_CIOIN Ensembl» | 
 | 
 | Ci-Tram1/2 | Translocating chain-associated membrane protein | Ciona intestinalis TI:7719 None |  |  |  | |||||
| Q58EH7_DANRE ZFIN» | 
 | 
 | zgc:113278 | Translocating chain-associated membrane protein | Danio rerio TI:7955 None |  |  |  | |||||
| Q6P4U7_DANRE ZFIN» | 
 | 
 | tram | Translocating chain-associated membrane protein | Danio rerio TI:7955 None |  |  |  | |||||
| Q802X7_DANRE ZFIN» | 
 | 
 | wu:fb20c11 | Translocating chain-associated membrane protein | Danio rerio TI:7955 None |  |  |  | |||||
| E9H3M1_DAPPU EnsemblMetazoa» | 
 | 
 | DAPPUDRAFT_325070 | Translocating chain-associated membrane protein | Daphnia pulex TI:6669 None |  |  |  | |||||
| Q9W5C2_DROME FlyBase» | 
 | 
 | TRAM | Translocating chain-associated membrane protein | Drosophila melanogaster TI:7227 None |  |  |  | |||||
| A0A3Q2GV83_HORSE Ensembl» | 
 | 
 | TRAM2 | Translocation associated membrane protein 2 | Equus caballus TI:9796 None |  |  | ||||||
| A0A3Q2HBF4_HORSE Ensembl» | 
 | 
 | TRAM1L1 | Translocation associated membrane protein 1 like 1 | Equus caballus TI:9796 None |  |  | ||||||
| A0A5F5Q0X1_HORSE Ensembl» | 
 | 
 | LACTB2 | Lactamase beta 2 | Equus caballus TI:9796 None |  |  | ||||||
| M3VZI1_FELCA Ensembl» | 
 | 
 | TRAM2 | Translocating chain-associated membrane protein | Felis catus TI:9685 None |  |  |  | |||||
| M3X7C1_FELCA Ensembl» | 
 | 
 | TRAM1 | Translocating chain-associated membrane protein | Felis catus TI:9685 None |  |  |  | |||||
| Q8AXQ0_CHICK Ensembl» | 
 | 
 | TRAM | Translocating chain-associated membrane protein | Gallus gallus TI:9031 None |  |  |  | |||||
| G3QD22_GORGO Ensembl» | 
 | 
 | TRAM1L1 | Translocating chain-associated membrane protein | Gorilla gorilla TI:9593 None |  |  |  | |||||
| G3QJX0_GORGO Ensembl» | 
 | 
 | TRAM1 | Translocation associated membrane protein 1 | Gorilla gorilla TI:9593 None |  |  |  | |||||
| G3R8C8_GORGO Ensembl» | 
 | 
 | TRAM2 | Translocating chain-associated membrane protein | Gorilla gorilla TI:9593 None |  |  |  | |||||
| T1G3D9_HELRO EnsemblMetazoa» | 
 | 
 | 20215587 | Translocating chain-associated membrane protein | Helobdella robusta TI:6412 None |  |  |  | |||||
| TR1L1_HUMAN Ensembl» | 
 | 
 | TRAM1L1 | Translocating chain-associated membrane protein 1-like 1 | Homo sapiens TI:9606 None |  |  |  | |||||
| TRAM1_HUMAN Ensembl» | 
 | 
 | TRAM1 | Translocating chain-associated membrane protein 1 (Protein TRAM1) | Homo sapiens TI:9606 None |  |  |  | |||||
| TRAM2_HUMAN Ensembl» | 
 | 
 | TRAM2 | Translocating chain-associated membrane protein 2 | Homo sapiens TI:9606 None |  |  |  | |||||
| B7P616_IXOSC EnsemblMetazoa» | 
 | 
 | IscW_ISCW000550 | Translocation associated membrane protein, putative (Translocation associated membrane protein, putative (Fragment)) | Ixodes scapularis TI:6945 None |  |  |  | |||||
| W5LXW4_LEPOC Ensembl» | 
 | 
 | Translocating chain-associated membrane protein | Lepisosteus oculatus TI:7918 None |  |  | |||||||
| W5M8N2_LEPOC Ensembl» | 
 | 
 | Translocating chain-associated membrane protein | Lepisosteus oculatus TI:7918 None |  |  |  | ||||||
| W5M8Z7_LEPOC Ensembl» | 
 | 
 | Translocating chain-associated membrane protein | Lepisosteus oculatus TI:7918 None |  |  |  | ||||||
| A0A5F7ZK86_MACMU Ensembl» | 
 | 
 | TRAM2 | Translocating chain-associated membrane protein | Macaca mulatta TI:9544 None |  |  | ||||||
| F7GCV4_MACMU Ensembl» | 
 | 
 | TRAM1 | Translocating chain-associated membrane protein | Macaca mulatta TI:9544 None |  |  |  | |||||
| F7HQE5_MACMU Ensembl» | 
 | 
 | TRAM1L1 | Translocating chain-associated membrane protein | Macaca mulatta TI:9544 None |  |  |  | |||||
| A0A5F8GF20_MONDO Ensembl» | 
 | 
 | Uncharacterized protein | Monodelphis domestica TI:13616 None |  |  | |||||||
| F6YZB4_MONDO Ensembl» | 
 | 
 | TRAM2 | Translocation associated membrane protein 2 | Monodelphis domestica TI:13616 None |  |  | ||||||
| F7EXV8_MONDO Ensembl» | 
 | 
 | TLC domain-containing protein | Monodelphis domestica TI:13616 None |  |  | |||||||
| TR1L1_MOUSE Ensembl» | 
 | 
 | Tram1l1 | Translocating chain-associated membrane protein 1-like 1 | Mus musculus TI:10090 None |  |  |  | |||||
| TRAM1_MOUSE Ensembl» | 
 | 
 | Tram1 | Translocating chain-associated membrane protein 1 (Protein TRAM1) | Mus musculus TI:10090 None |  |  |  | |||||
| TRAM2_MOUSE Ensembl» | 
 | 
 | Tram2 | Translocating chain-associated membrane protein 2 | Mus musculus TI:10090 None |  |  |  | |||||
| A7S839_NEMVE EnsemblMetazoa» | 
 | 
 | NEMVEDRAFT_v1g108310 | TLC domain-containing protein | Nematostella vectensis TI:45351 None |  |  |  | |||||
| A7S840_NEMVE EnsemblMetazoa» | 
 | 
 | NEMVEDRAFT_v1g186830 | Translocating chain-associated membrane protein | Nematostella vectensis TI:45351 None |  |  |  | |||||
| A7T828_NEMVE EnsemblMetazoa» | 
 | 
 | NEMVEDRAFT_v1g223617 | TLC domain-containing protein | Nematostella vectensis TI:45351 None |  |  |  | |||||
| A0A6I8N2E0_ORNAN Ensembl» | 
 | 
 | TLC domain-containing protein | Ornithorhynchus anatinus TI:9258 None |  |  | |||||||
| A0A6I8NRY7_ORNAN Ensembl» | 
 | 
 | TRAM2 | Translocating chain-associated membrane protein | Ornithorhynchus anatinus TI:9258 None |  |  | ||||||
| H2LVK8_ORYLA Ensembl» | 
 | 
 | tram1 | Translocating chain-associated membrane protein | Oryzias latipes TI:8090 None |  |  | ||||||
| H2M9D4_ORYLA Ensembl» | 
 | 
 | LOC101155768 | Translocating chain-associated membrane protein | Oryzias latipes TI:8090 None |  |  | ||||||
| H2MCG9_ORYLA Ensembl» | 
 | 
 | LOC101161454 | Translocating chain-associated membrane protein | Oryzias latipes TI:8090 None |  |  | ||||||
| H2QWA3_PANTR Ensembl» | 
 | 
 | TRAM1 | Translocating chain-associated membrane protein | Pan troglodytes TI:9598 None |  |  |  | |||||
| H2RFU8_PANTR Ensembl» | 
 | 
 | TRAM2 | Translocating chain-associated membrane protein | Pan troglodytes TI:9598 None |  |  |  | |||||
| A0A8R1Z766_PRIPA EnsemblMetazoa» | 
 | 
 | WBGene00304377 | TLC domain-containing protein | Pristionchus pacificus TI:54126 None |  |  | ||||||
| F1LUA2_RAT RGD» | 
 | 
 | Tram2 | Translocating chain-associated membrane protein | Rattus norvegicus TI:10116 None |  |  | ||||||
| TRAM1_RAT RGD» | 
 | 
 | Tram1 | Translocating chain-associated membrane protein 1 (Protein TRAM1) | Rattus norvegicus TI:10116 None |  |  |  | |||||
| A0A7M7N2H9_STRPU EnsemblMetazoa» | 
 | 
 | TLC domain-containing protein | Strongylocentrotus purpuratus TI:7668 None |  |  | |||||||
| A0A287A9W0_PIG Ensembl» | 
 | 
 | TRAM2 | Translocation associated membrane protein 2 | Sus scrofa TI:9823 None |  |  | ||||||
| A0A287AY88_PIG Ensembl» | 
 | 
 | TRAM1 | Translocation associated membrane protein 1 | Sus scrofa TI:9823 None |  |  | ||||||
| A0A8W4FI69_PIG Ensembl» | 
 | 
 | TRAM1L1 | Translocating chain-associated membrane protein | Sus scrofa TI:9823 None |  |  | ||||||
| D6WFR2_TRICA EnsemblMetazoa» | 
 | 
 | AUGUSTUS-3.0.2_01570 | Translocating chain-associated membrane protein 1-like Protein | Tribolium castaneum TI:7070 None |  |  |  | |||||
| B3S439_TRIAD EnsemblMetazoa» | 
 | 
 | TRIADDRAFT_58943 | TLC domain-containing protein | Trichoplax adhaerens TI:10228 None |  |  |  | |||||
| A0A1L8G5V6_XENLA Xenbase» | 
 | 
 | tram2.S | Translocating chain-associated membrane protein | Xenopus laevis TI:8355 None |  |  | ||||||
| B4F6I6_XENTR Xenbase» | 
 | 
 | tram2 | Translocating chain-associated membrane protein | Xenopus tropicalis TI:8364 None |  |  |  | |||||
| Q5HZN0_XENLA Xenbase» | 
 | 
 | tram2.L | Translocating chain-associated membrane protein | Xenopus laevis TI:8355 None |  |  |  | |||||
| Q6NVP0_XENTR Xenbase» | 
 | 
 | tram1 | Translocating chain-associated membrane protein | Xenopus tropicalis TI:8364 None |  |  |  | |||||
| Q90ZM0_XENLA Xenbase» | 
 | 
 | tram1.S | Translocating chain-associated membrane protein | Xenopus laevis TI:8355 None |  |  |  | |||||
| TR1L1_XENLA Xenbase» | 
 | 
 | tram1l1 | Translocating chain-associated membrane protein 1-like 1 | Xenopus laevis TI:8355 None |  |  |  | |||||