Collated Gene Ontology terms

Biological process: signaling receptor activity(2003)

Molecular function: protein insertion into ER membrane2016, 2021, 2025 SRP-dependent cotranslational protein targeting to membrane, translocation2015, 2025 protein transport2025 response to unfolded protein2021, 2025 cotranslational protein targeting to membrane2003, 2021, 2025 collagen biosynthetic process2009, 2025 sphingolipid metabolic process2024 determination of heart left/right asymmetry2020

Cellular component: endoplasmic reticulum membrane2010, 2018, 2021, 2024, 2025 membrane2003, 2025 endoplasmic reticulum2003, 2015, 2025 rough endoplasmic reticulum2013, 2025 periciliary membrane compartment2014, 2025 dendrite terminus2015, 2025

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
Q7QDS0_ANOGA
EnsemblMetazoa»
0.0
1272659 AGAP010386-PA Anopheles gambiae
TI:7165 None
 
A0A7M7N2H9_STRPU
EnsemblMetazoa»
0.0
TLC domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A8R1Z766_PRIPA
EnsemblMetazoa»
0.0
WBGene00304377 TLC domain-containing protein Pristionchus pacificus
TI:54126 None
   
A0ABI7XDS2_FELCA
Ensembl»
0.0
TRAM1 TLC domain-containing protein Felis catus
TI:9685 None
   
A0ABI7YCC6_FELCA
Ensembl»
0.0
TRAM2 TLC domain-containing protein Felis catus
TI:9685 None
   
A7S839_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g108310 TLC domain-containing protein Nematostella vectensis
TI:45351 None
 
A7T828_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g223617 TLC domain-containing protein Nematostella vectensis
TI:45351 None
 
B3S439_TRIAD
CTD»
0.0
TRIADDRAFT_58943 TLC domain-containing protein Trichoplax adhaerens
TI:10228 None
 
A0A287BDF6_PIG
Ensembl»
0.0
TRAM1 Translocating chain-associated
membrane protein 1		 Sus scrofa
TI:9823 None
   
A0A5F5Q0X1_HORSE
Ensembl»
0.0
TRAM1 Translocating chain-associated
membrane protein 1		 Equus caballus
TI:9796 None
   
A0A6I8N2E0_ORNAN
Ensembl»
0.0
TRAM1 Translocating chain-associated
membrane protein 1		 Ornithorhynchus anatinus
TI:9258 None
   
F7EXV8_MONDO
Ensembl»
0.0
Translocating chain-associated
membrane protein 1		 Monodelphis domestica
TI:13616 None
   
G3QJX0_GORGO
Ensembl»
0.0
TRAM1 Translocating chain-associated
membrane protein 1		 Gorilla gorilla
TI:9593 None
 
TRAM2_HUMAN
Ensembl»
2.1
TRAM2 Translocating chain-associated
membrane protein 2		 Homo sapiens
TI:9606 None
 
TRAM2_MOUSE
Ensembl»
2.0
Tram2 Translocating chain-associated
membrane protein 2		 Mus musculus
TI:10090 None
 
A0A9J7HIK3_BRAFL
euHCVdb»
0.0
LOC118404847 Translocating chain-associated membrane
protein 1-like isoform X1		 Branchiostoma floridae
TI:7739 None
   
D6WFR2_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_01570 Translocating chain-associated membrane
protein 1-like Protein		 Tribolium castaneum
TI:7070 None
 
TR1L1_HUMAN
Ensembl»
0.5
TRAM1L1 Translocating chain-associated membrane
protein 1-like 1		 Homo sapiens
TI:9606 None
 
TR1L1_MOUSE
Ensembl»
0.5
Tram1l1 Translocating chain-associated membrane
protein 1-like 1		 Mus musculus
TI:10090 None
 
TR1L1_XENLA
Xenbase»
0.0
tram1l1 Translocating chain-associated membrane
protein 1-like 1		 Xenopus laevis
TI:8355 None
 
TRAM1_BOVIN
Ensembl»
0.0
TRAM1 Translocating chain-associated membrane
protein 1 (Protein TRAM1)		 Bos taurus
TI:9913 None
 
TRAM1_CANLF
Ensembl»
0.0
TRAM1 Translocating chain-associated membrane
protein 1 (Protein TRAM1)		 Canis lupus
TI:9612 None
 
TRAM1_HUMAN
Ensembl»
4.7
TRAM1 Translocating chain-associated membrane
protein 1 (Protein TRAM1)		 Homo sapiens
TI:9606 None
 
TRAM1_MOUSE
Ensembl»
3.5
Tram1 Translocating chain-associated membrane
protein 1 (Protein TRAM1)		 Mus musculus
TI:10090 None
 
TRAM1_RAT
RGD»
4.0
Tram1 Translocating chain-associated membrane
protein 1 (Protein TRAM1)		 Rattus norvegicus
TI:10116 None
 
A0A1L8G5V6_XENLA
Xenbase»
0.0
tram2.S Translocating chain-associated membrane protein Xenopus laevis
TI:8355 None
   
A0A3Q2HBF4_HORSE
Ensembl»
0.0
TRAM1L1 Translocating chain-associated membrane protein Equus caballus
TI:9796 None
   
A0A5F7ZK86_MACMU
Ensembl»
0.0
TRAM2 Translocating chain-associated membrane protein Macaca mulatta
TI:9544 None
   
A0A6I8NRY7_ORNAN
Ensembl»
0.0
TRAM2 Translocating chain-associated membrane protein Ornithorhynchus anatinus
TI:9258 None
   
A0A803U1L2_ANOCA
Ensembl»
0.0
LOC100563926 Translocating chain-associated membrane protein Anolis carolinensis
TI:28377 None
   
A0A8W4FI69_PIG
Ensembl»
0.0
TRAM1L1 Translocating chain-associated membrane protein Sus scrofa
TI:9823 None
   
A0ABI7W6W1_FELCA
Ensembl»
0.0
TRAM1 Translocating chain-associated membrane protein Felis catus
TI:9685 None
   
A0ABK0LZ70_RAT
Ensembl»
0.0
Tram1l1 Translocating chain-associated membrane protein Rattus norvegicus
TI:10116 None
   
A7S840_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g186830 Translocating chain-associated membrane protein Nematostella vectensis
TI:45351 None
 
A8WUY1_CAEBR
WormBase»
0.0
tram-1 Translocating chain-associated membrane protein Caenorhabditis briggsae
TI:6238 None
 
B4F6I6_XENTR
Xenbase»
0.0
tram2 Translocating chain-associated membrane protein Xenopus tropicalis
TI:8364 None
 
E1BCM2_BOVIN
Ensembl»
0.0
TRAM2 Translocating chain-associated membrane protein Bos taurus
TI:9913 None
   
E9H3M1_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_325070 Translocating chain-associated membrane protein Daphnia pulex
TI:6669 None
 
F7GCV4_MACMU
Ensembl»
0.0
TRAM1 Translocating chain-associated membrane protein Macaca mulatta
TI:9544 None
 
F7HQE5_MACMU
Ensembl»
0.0
TRAM1L1 Translocating chain-associated membrane protein Macaca mulatta
TI:9544 None
 
G1KDK7_ANOCA
Ensembl»
0.0
TRAM2 Translocating chain-associated membrane protein Anolis carolinensis
TI:28377 None
   
G1KQI6_ANOCA
Ensembl»
0.0
tram1 Translocating chain-associated membrane protein Anolis carolinensis
TI:28377 None
   
G3QD22_GORGO
Ensembl»
0.0
TRAM1L1 Translocating chain-associated membrane protein Gorilla gorilla
TI:9593 None
 
G3R8C8_GORGO
Ensembl»
0.0
TRAM2 Translocating chain-associated membrane protein Gorilla gorilla
TI:9593 None
 
H2LVK8_ORYLA
Ensembl»
0.0
TRAM1L1 Translocating chain-associated membrane protein Oryzias latipes
TI:8090 None
   
H2M9D4_ORYLA
Ensembl»
0.0
zgc:113278 Translocating chain-associated membrane protein Oryzias latipes
TI:8090 None
   
H2MCG9_ORYLA
Ensembl»
0.0
TRAM2 Translocating chain-associated membrane protein Oryzias latipes
TI:8090 None
   
H2QWA3_PANTR
Ensembl»
0.0
TRAM1 Translocating chain-associated membrane protein Pan troglodytes
TI:9598 None
 
H2RFU8_PANTR
Ensembl»
0.0
TRAM2 Translocating chain-associated membrane protein Pan troglodytes
TI:9598 None
 
Q58EH7_DANRE
ZFIN»
0.5
zgc:113278 Translocating chain-associated membrane protein Danio rerio
TI:7955 None
 
Q5HZN0_XENLA
Xenbase»
0.0
tram2.L Translocating chain-associated membrane protein Xenopus laevis
TI:8355 None
 
Q68A32_CIOIN
Ensembl»
0.0
Ci-Tram1/2 Translocating chain-associated membrane protein Ciona intestinalis
TI:7719 None
 
Q6NVP0_XENTR
Xenbase»
0.0
tram1 Translocating chain-associated membrane protein Xenopus tropicalis
TI:8364 None
 
Q6P4U7_DANRE
ZFIN»
1.3
tram1 Translocating chain-associated membrane protein Danio rerio
TI:7955 None
 
Q802X7_DANRE
ZFIN»
0.5
tram2 Translocating chain-associated membrane protein Danio rerio
TI:7955 None
 
Q8AXQ0_CHICK
Ensembl»
0.5
TRAM Translocating chain-associated membrane protein Gallus gallus
TI:9031 None
 
Q90ZM0_XENLA
Xenbase»
0.0
tram1.S Translocating chain-associated membrane protein Xenopus laevis
TI:8355 None
 
Q9W5C2_DROME
FlyBase»
0.5
TRAM Translocating chain-associated membrane protein Drosophila melanogaster
TI:7227 None
 
Q9XXK7_CAEEL
WormBase»
1.0
tram-1 Translocating chain-associated membrane protein Caenorhabditis elegans
TI:6239 None
 
T1G3D9_HELRO
EnsemblMetazoa»
0.0
20215587 Translocating chain-associated membrane protein Helobdella robusta
TI:6412 None
 
W5LXW4_LEPOC
Ensembl»
0.0
Translocating chain-associated membrane protein Lepisosteus oculatus
TI:7918 None
   
W5M8N2_LEPOC
Ensembl»
0.0
Translocating chain-associated membrane protein Lepisosteus oculatus
TI:7918 None
 
W5M8Z7_LEPOC
Ensembl»
0.0
Translocating chain-associated membrane protein Lepisosteus oculatus
TI:7918 None
 
B7P616_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW000550 Translocation associated
membrane protein, putative		 Ixodes scapularis
TI:6945 None
 
A0A8I3S761_CANLF
Ensembl»
0.0
TRAM1L1 Translocation associated membrane
protein 1 like 1		 Canis lupus
TI:9612 None
   
A0AAA9S714_BOVIN
Ensembl»
0.0
TRAM1L1 Translocation associated membrane
protein 1 like 1		 Bos taurus
TI:9913 None
   
A0A287A9W0_PIG
Ensembl»
0.0
TRAM2 Translocation associated membrane protein 2 Sus scrofa
TI:9823 None
   
A0A3Q2GV83_HORSE
Ensembl»
0.0
TRAM2 Translocation associated membrane protein 2 Equus caballus
TI:9796 None
   
A0A8I3N8J0_CANLF
Ensembl»
0.0
TRAM2 Translocation associated membrane protein 2 Canis lupus
TI:9612 None
   
A0ABK0LU55_RAT
Ensembl»
1.0
Tram2 Translocation associated membrane protein 2 Rattus norvegicus
TI:10116 None
   
F6YZB4_MONDO
Ensembl»
0.0
TRAM2 Translocation associated membrane protein 2 Monodelphis domestica
TI:13616 None
   
A0A5F8GF20_MONDO
Ensembl»
0.0
Uncharacterized protein Monodelphis domestica
TI:13616 None
   
A0A803SQ34_ANOCA
Ensembl»
0.0
Uncharacterized protein Anolis carolinensis
TI:28377 None
   
A0A803T1Y7_ANOCA
Ensembl»
0.0
Uncharacterized protein Anolis carolinensis
TI:28377 None
   
A0A803TV90_ANOCA
Ensembl»
0.0
Uncharacterized protein Anolis carolinensis
TI:28377 None