Collated Gene Ontology terms

Biological process: growth factor activity(2023) sulfatide binding(2018, 2022, 2023) lipid binding(2023) transferase activity(2023) calcium ion binding(2023) RNA binding(2014)

Molecular function: neuron projection development2009, 2017 dopaminergic neuron differentiation2012, 2017 signal transduction2023 regulation of response to endoplasmic reticulum stress2018, 2022, 2023 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure2012, 2023 response to unfolded protein2023 regulation of dopaminergic neuron differentiation2023 developmental growth2018, 2022 synaptic transmission, dopaminergic2010 neuron cellular homeostasis2009
dopamine metabolic process2013

Cellular component: extracellular region2013, 2016, 2023 endoplasmic reticulum2013, 2017, 2023 extracellular space2007, 2017 endoplasmic reticulum lumen2018, 2023 sarcoplasmic reticulum lumen2023 sarcoplasmic reticulum2023 perinuclear region of cytoplasm2010 membrane2023 synapse2023 nucleus2014
endomembrane system2014 cytosol2016

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 0 2 4 6 8 10 Knownness

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
MANF_CAEEL
WormBase»
3.4
manf-1 Mesencephalic astrocyte-derived neurotrophic factor
homolog (ARMET-like protein) (MANF/CDNF-like protein)		 Caenorhabditis elegans
TI:6239 None
 
A4QNW4_DANRE
ZFIN»
1.8
cdnf Cerebral dopamine neurotrophic factor (Cerebral
dopamine neurotrophic factor precursor) (Zgc:162209 protein)		 Danio rerio
TI:7955 None
 
Q08CA7_DANRE
ZFIN»
1.8
zgc:153327 Mesencephalic astrocyte-derived neurotrophic factor
precursor (Zgc:153327) (Zgc:153327 protein)		 Danio rerio
TI:7955 None
 
ARMET_DROME
FlyBase»
4.2
Manf Mesencephalic astrocyte-derived neurotrophic factor
homolog (DmMANF) (MANF/CDNF-like protein)		 Drosophila melanogaster
TI:7227 None
 
A0A8V1A7N4_CHICK
Ensembl»
0.0
MANF Mesencephalic astrocyte
derived neurotrophic factor		 Gallus gallus
TI:9031 None 		     
CDNF_HUMAN
Ensembl»
1.0
CDNF Cerebral dopamine neurotrophic factor (ARMET-like
protein 1) (Conserved dopamine neurotrophic factor)		 Homo sapiens
TI:9606 None
 
MANF_HUMAN
Ensembl»
3.1
MANF Mesencephalic astrocyte-derived neurotrophic factor
(Arginine-rich protein) (Protein ARMET)		 Homo sapiens
TI:9606 None
 
CDNF_MOUSE
Ensembl»
1.0
Cdnf Cerebral dopamine neurotrophic factor (ARMET-like
protein 1) (Conserved dopamine neurotrophic factor)		 Mus musculus
TI:10090 None
 
MANF_MOUSE
Ensembl»
2.8
Manf Mesencephalic astrocyte-derived neurotrophic factor
(Arginine-rich protein) (Protein ARMET)		 Mus musculus
TI:10090 None
 
CDNF_RAT
RGD»
1.0
Cdnf Cerebral dopamine neurotrophic factor (ARMET-like protein 1) (Arginine-rich protein
mutated in early stage tumors-like 1) (Conserved dopamine neurotrophic factor)		 Rattus norvegicus
TI:10116 None
 
MANF_RAT
RGD»
2.5
Manf Mesencephalic astrocyte-derived neurotrophic factor
(Arginine-rich protein) (Protein ARMET)		 Rattus norvegicus
TI:10116 None