Collated Gene Ontology terms

Biological process: SH3 domain binding(2025) protein-macromolecule adaptor activity(2025) ubiquitin-like ligase-substrate adaptor activity(2022, 2025) protein-RNA adaptor activity(2022, 2025) glutathione transferase activity(2022)

Molecular function: cytoskeleton organization2022, 2025 proteasome-mediated ubiquitin-dependent protein catabolic process2022, 2025 positive regulation of cytoplasmic translational initiation2022, 2025 positive regulation of actin filament bundle assembly2025

Cellular component: cytosol2022, 2025 nucleus2005, 2025 ruffle membrane2022, 2025 plasma membrane2025 nucleoplasm2024, 2025 cytoplasm2005, 2025 extracellular exosome2013, 2014 nuclear membrane2025 nuclear body2025 extracellular space2013

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 0/1 
Porifera: 0/0 
Choanoflagellates+: 7/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
SH3L2_HUMAN
Ensembl»
0.5
SH3BGRL2 SH3 domain-binding glutamic acid-rich-like protein
2 (Fovea-associated SH3 domain-binding protein)		 Homo sapiens
TI:9606 None
 
SH3BG_HUMAN
Ensembl»
0.5
SH3BGR SH3 domain-binding glutamic acid-rich protein
(SH3BGR protein) (21-glutamic acid-rich protein) (21-GARP)		 Homo sapiens
TI:9606 None
 
SH3L1_MOUSE
Ensembl»
4.0
Sh3bgrl Adapter Sh3bgrl (SH3 domain-binding
glutamic acid-rich-like protein 1)		 Mus musculus
TI:10090 None
 
SH3L1_HUMAN
Ensembl»
5.2
SH3BGRL Adapter SH3BGRL (SH3 domain-binding
glutamic acid-rich-like protein 1)		 Homo sapiens
TI:9606 None
 
SH3L3_HUMAN
Ensembl»
2.1
SH3BGRL3 SH3 domain-binding glutamic acid-rich-like protein 3 (SH3 domain-binding
protein 1) (SH3BP-1) (TNF inhibitory protein B1) (TIP-B1)		 Homo sapiens
TI:9606 None
 
Q7T2A8_DANRE
ZFIN»
2.0
sh3bgrl SH3 domain-binding
glutamic acid-rich-like protein		 Danio rerio
TI:7955 None
 
SH3BG_DROME
FlyBase»
0.0
Sh3beta SH3 domain-binding glutamic acid-rich
protein homolog (SH3BGR protein)		 Drosophila melanogaster
TI:7227 None
 
SH3L2_MOUSE
Ensembl»
0.5
Sh3bgrl2 SH3 domain-binding glutamic
acid-rich-like protein 2		 Mus musculus
TI:10090 None
 
Q7ZUC9_DANRE
ZFIN»
0.5
sh3bgrl3 SH3 domain-binding glutamic
acid-rich-like protein 3		 Danio rerio
TI:7955 None
 
SH3L3_MOUSE
Ensembl»
1.5
Sh3bgrl3 SH3 domain-binding glutamic
acid-rich-like protein 3		 Mus musculus
TI:10090 None
 
SH3L3_RAT
RGD»
1.5
Sh3bgrl3 SH3 domain-binding glutamic acid-rich-like protein
3 (TNF inhibitory protein B1) (TIP-B1)		 Rattus norvegicus
TI:10116 None
 
K8ES47_CAEEL
WormBase»
0.0
CELE_Y105E8A.1 Y105E8A.1 Glutaredoxin domain-containing protein Caenorhabditis elegans
TI:6239 None
 
Q54XE7_DICDI
dictyBase»
0.0
DDB_G0279011 Thioredoxin domain-containing protein Dictyostelium discoideum
TI:44689 None 		 
 
SH3BG_MOUSE
Ensembl»
0.5
Sh3bgr SH3 domain-binding glutamic
acid-rich protein (SH3BGR protein)		 Mus musculus
TI:10090 None
 
SH3L2_DANRE
ZFIN»
0.5
sh3bgrl2 SH3 domain-binding glutamic
acid-rich-like protein 2		 Danio rerio
TI:7955 None
 
A0A8I6GHH3_RAT
RGD»
4.0
Sh3bgrl SH3 domain-binding glutamic
acid-rich-like protein 1		 Rattus norvegicus
TI:10116 None
   
A0A8M1P0S2_DANRE
ZFIN»
0.5
zgc:153284 Uncharacterized protein LOC751696 isoform 1 Danio rerio
TI:7955 None
   
A0A8M2BH31_DANRE
ZFIN»
0.5
sh3bgr SH3 domain-binding glutamic
acid-rich protein isoform X1		 Danio rerio
TI:7955 None
   
A0A8V0XFH0_CHICK
Ensembl»
0.5
SH3BGRL2 SH3 domain-binding
glutamic acid-rich-like protein		 Gallus gallus
TI:9031 None
   
A0A8V0YLT6_CHICK
Ensembl»
0.5
SH3BGRL3 SH3 domain-binding glutamic
acid-rich-like protein 3		 Gallus gallus
TI:9031 None
   
A0A8V0YSJ7_CHICK
Ensembl»
0.5
SH3BGR SH3 domain binding glutamate rich protein Gallus gallus
TI:9031 None
   
A0A8V0Z2K4_CHICK
Ensembl»
2.0
SH3BGRL SH3 domain-binding glutamic
acid-rich-like protein 1		 Gallus gallus
TI:9031 None
   
A0ABK0LV52_RAT
RGD»
0.0
Sh3bgrl2 SH3 domain binding glutamate-rich protein like 2 Rattus norvegicus
TI:10116 None
   
D4AAC3_RAT
RGD»
0.5
Sh3bgr SH3 domain binding glutamate-rich protein Rattus norvegicus
TI:10116 None