Collated Gene Ontology terms

Biological process: cholesterol transfer activity(2018, 2021, 2024) cholesterol binding(2018, 2021, 2024) sterol transfer activity(2018, 2019, 2020, 2021, 2024) sterol binding(2015, 2021) phosphatidylserine binding(2018, 2024) phosphatidic acid binding(2018, 2024) lipid binding(2020, 2024)

Molecular function: intracellular sterol transport2015, 2021, 2024 cellular response to cholesterol2018, 2024 sterol transport2021, 2024 cholesterol homeostasis2018, 2024 lipid transport2024 autophagy2024 protein targeting to vacuole2021 positive regulation of gene expression2024 piecemeal microautophagy of the nucleus2021 intermembrane sterol transfer2020
cellular response to rapamycin2022 apoptotic process2024 aggregation involved in sorocarp development2022

Cellular component: endoplasmic reticulum membrane2018, 2023, 2024 plasma membrane2014, 2018, 2023, 2024 endoplasmic reticulum-plasma membrane contact site2018, 2020, 2021, 2024 membrane2014, 2024 organelle membrane contact site2018, 2024 organelle2024 mitochondrion2013, 2018, 2021, 2024 cortical endoplasmic reticulum2015, 2021 endoplasmic reticulum2018, 2024 intracellular membrane-bounded organelle2024
cytosol2023, 2024 nucleus-vacuole junction2015, 2017 cytoplasmic vesicle2024 cytoplasm2018, 2024 autophagosome2024 perinuclear endoplasmic reticulum membrane2020, 2024 mitochondria-associated endoplasmic reticulum membrane2015 vacuole-mitochondrion membrane contact site2015 mitochondrial membrane2024 cell periphery2018

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 14/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 2/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
ASTRA_RAT
RGD»
4.5
Gramd1a Protein Aster-A (EG1RVC)
(GRAM domain-containing protein 1A)		 Rattus norvegicus
TI:10116 None
 
A0A8I6A887_RAT
RGD»
4.5
Gramd1b GRAM domain containing 1B Rattus norvegicus
TI:10116 None
   
ASTRA_HUMAN
Ensembl»
3.0
GRAMD1A Protein Aster-A (GRAM
domain-containing protein 1A)		 Homo sapiens
TI:9606 None
 
YSP2_YEAST
SGD»
4.7
YSP2 Membrane-anchored lipid-binding protein YSP2 (Lipid transfer at contact site protein 4) (Lipid
transfer protein anchored at membrane contact sites 3) (Yeast suicide protein 2)		 Saccharomyces cerevisiae
TI:4932 None
 
ASTRB_HUMAN
Ensembl»
4.5
GRAMD1B Protein Aster-B (GRAM
domain-containing protein 1B)		 Homo sapiens
TI:9606 None
 
ASTRC_HUMAN
Ensembl»
3.0
GRAMD1C Protein Aster-C (GRAM
domain-containing protein 1C)		 Homo sapiens
TI:9606 None
 
ASTRA_MOUSE
Ensembl»
2.4
Gramd1a Protein Aster-A (GRAM
domain-containing protein 1A)		 Mus musculus
TI:10090 None
 
A0A5G2QL79_PIG
Ensembl»
0.0
GRAMD1B GRAM domain containing 1B Sus scrofa
TI:9823 None
   
F7G3Z6_MONDO
Ensembl»
0.0
GRAMD1B GRAM domain containing 1B Monodelphis domestica
TI:13616 None
   
LAM6_YEAST
SGD»
3.1
LAM6 Membrane-anchored lipid-binding protein LAM6 (Lipid transfer at contact site protein
1) (Lipid transfer protein anchored at membrane contact sites 1)		 Saccharomyces cerevisiae
TI:4932 None
 
M3W1Z8_FELCA
Ensembl»
0.0
GRAMD1B GRAM domain containing 1B Felis catus
TI:9685 None
 
ASTRB_MOUSE
Ensembl»
4.8
Gramd1b Protein Aster-B (GRAM
domain-containing protein 1B)		 Mus musculus
TI:10090 None
 
LAM4_YEAST
SGD»
3.9
LAM4 Membrane-anchored lipid-binding protein LAM4 (Lipid transfer at contact site protein
3) (Lipid transfer protein anchored at membrane contact sites 1)		 Saccharomyces cerevisiae
TI:4932 None
 
LAM5_YEAST
SGD»
2.5
LAM5 Membrane-anchored lipid-binding protein LAM5 (Lipid transfer at contact site protein
2) (Lipid transfer protein anchored at membrane contact sites 1)		 Saccharomyces cerevisiae
TI:4932 None
 
YGZ7_SCHPO
PomBase»
3.9
SPBC20F10.07 Uncharacterized membrane protein C20F10.07 Schizosaccharomyces pombe
TI:4896 None
 
A0A5F5XYK9_FELCA
Ensembl»
0.0
GRAMD1A GRAM domain containing 1A Felis catus
TI:9685 None
 
F6QVR0_BOVIN
Ensembl»
0.0
GRAMD1A GRAM domain containing 1A Bos taurus
TI:9913 None
   
A0A3Q1LXS5_BOVIN
Ensembl»
0.0
GRAMD1B GRAM domain containing 1B Bos taurus
TI:9913 None
   
F1SP95_PIG
Ensembl»
0.0
GRAMD1C GRAM domain containing 1C Sus scrofa
TI:9823 None
   
F6QIT1_HORSE
Ensembl»
0.0
GRAMD1C GRAM domain containing 1C Equus caballus
TI:9796 None
   
G3R234_GORGO
Ensembl»
0.0
GRAMD1C GRAM domain containing 1C Gorilla gorilla
TI:9593 None
 
H2R140_PANTR
Ensembl»
0.0
GRAMD1C GRAM domain containing 1C Pan troglodytes
TI:9598 None
 
M3WWM4_FELCA
Ensembl»
0.0
GRAMD1C GRAM domain containing 1C Felis catus
TI:9685 None
 
A0A1D8PE20_CANAL
EnsemblFungi»
0.0
CAALFM_C107440WA orf19.11901 VASt domain-containing protein Candida albicans
TI:5476 None
 
ASTRC_MOUSE
Ensembl»
2.4
Gramd1c Protein Aster-C (GRAM
domain-containing protein 1C)		 Mus musculus
TI:10090 None
 
B6K0D6_SCHJY
EnsemblFungi»
0.0
SJAG_01329 GRAM domain-containing protein Schizosaccharomyces japonicus
TI:4897 None
 
A0A5G2QQB5_PIG
Ensembl»
0.0
GRAMD1A GRAM domain containing 1A Sus scrofa
TI:9823 None
   
A0A8I6AME7_RAT
RGD»
1.5
Gramd1c GRAM domain containing 1C Rattus norvegicus
TI:10116 None
   
F4P1K5_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_87991 Uncharacterized protein Batrachochytrium dendrobatidis
TI:109871 None
 
Q55FU7_DICDI
dictyBase»
3.9
DDB_G0267942 GRAM domain-containing protein Dictyostelium discoideum
TI:44689 None
 
A0A1D8PPH7_CANAL
EnsemblFungi»
0.0
CAALFM_C600890WA orf19.7736 VASt domain-containing protein Candida albicans
TI:5476 None
 
A0A3B3HQA0_ORYLA
Ensembl»
0.0
gramd1a GRAM domain containing 1A Oryzias latipes
TI:8090 None
   
A0A3B3IBI2_ORYLA
Ensembl»
0.0
gramd1b GRAM domain containing 1B Oryzias latipes
TI:8090 None
   
A0A5F8G1V0_MONDO
Ensembl»
0.0
GRAMD1A GRAM domain containing 1A Monodelphis domestica
TI:13616 None
   
A0A6I8NW78_ORNAN
Ensembl»
0.0
GRAM domain containing 1B Ornithorhynchus anatinus
TI:9258 None
   
A0A6I8PKJ0_ORNAN
Ensembl»
0.0
GRAMD1C GRAM domain containing 1C Ornithorhynchus anatinus
TI:9258 None
   
A0A8M2B566_DANRE
CTD»
1.5
gramd1a GRAM domain-containing protein 1A isoform X1 Danio rerio
TI:7955 None
   
A0A8M9Q6Q6_DANRE
CTD»
1.5
gramd1ba GRAM domain-containing protein
1B-like isoform X2		 Danio rerio
TI:7955 None
   
A0A8M9Q853_DANRE
CTD»
1.5
gramd1c GRAM domain-containing protein 1C isoform X1 Danio rerio
TI:7955 None
   
E3LBH0_PUCGT
EnsemblFungi»
0.0
PGTG_19923 VASt domain-containing protein Puccinia graminis
TI:5297 None
 
F4NUU6_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_85160 VASt domain-containing protein Batrachochytrium dendrobatidis
TI:109871 None
 
F4PEG3_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_92706 GRAM domain-containing protein Batrachochytrium dendrobatidis
TI:109871 None
 
H9GAI1_ANOCA
Ensembl»
0.0
VASt domain-containing protein Anolis carolinensis
TI:28377 None
   
Q4WU40_ASPFU
EnsemblFungi»
0.0
AFUA_5G07100 GRAM domain protein Aspergillus fumigatus
TI:746128 None
 
Q5BB65_EMENI
EnsemblFungi»
0.0
ANIA_02215 GRAM domain
protein (AFU_orthologue AFUA_5G07100)		 Emericella nidulans
TI:162425 None
 
Q5KNJ2_CRYNJ
EnsemblFungi»
0.0
CNA06300 VASt domain-containing protein Cryptococcus neoformans
TI:5207 None
 
Q6CGT7_YARLI
EnsemblFungi»
0.0
YALI0_A16291g YALI0A16291p Yarrowia lipolytica
TI:4952 None
 
Q759H0_ASHGO
EnsemblFungi»
0.0
AGOS_ADR294C ADR294Cp Ashbya gossypii
TI:33169 None
 
Q75CZ1_ASHGO
EnsemblFungi»
0.0
AGOS_ABR231W ABR231Wp Ashbya gossypii
TI:33169 None
 
V5IMX1_NEUCR
EnsemblFungi»
0.0
NCU06999 VASt domain-containing protein Neurospora crassa
TI:5141 None
 
W5M5I8_LEPOC
Ensembl»
0.0
GRAM domain containing 1c Lepisosteus oculatus
TI:7918 None
 
W5MC68_LEPOC
Ensembl»
0.0
GRAM domain containing 1A Lepisosteus oculatus
TI:7918 None
 
A0A7M7NB39_STRPU
EnsemblMetazoa»
0.0
VASt domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7SV96_STRPU
EnsemblMetazoa»
0.0
VASt domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A8XG60_CAEBR
WormBase»
0.0
CBG12618 CBG_12618 Protein CBG12618 Caenorhabditis briggsae
TI:6238 None
 
B3RW86_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_55922 VASt domain-containing protein Trichoplax adhaerens
TI:10228 None
 
D6WAV3_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_00335 GRAM domain-containing protein 1B-like Protein Tribolium castaneum
TI:7070 None
 
F4P1H5_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_88351 VASt domain-containing protein Batrachochytrium dendrobatidis
TI:109871 None
 
H2L0J6_CAEEL
WormBase»
1.5
CELE_ZC328.3 ZC328.3 VASt domain-containing protein Caenorhabditis elegans
TI:6239 None
 
R9PY62_DROME
FlyBase»
1.5
GramD1B GRAM domain containing 1B, isoform E Drosophila melanogaster
TI:7227 None
 
A0A146M1U1_PLAF7
EnsemblProtists»
0.0
PF3D7_0803600.1 GRAM domain-containing protein Plasmodium falciparum
TI:5833 None
 
A0A7M7N9L1_STRPU
EnsemblMetazoa»
0.0
GRAM domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A8I3Q447_CANLF
Ensembl»
0.0
GRAMD1C GRAM domain containing 1C Canis lupus
TI:9612 None
   
A0A8J1L8Y9_XENLA
Xenbase»
0.0
LOC108695813 Protein Aster-B isoform X1 Xenopus laevis
TI:8355 None
   
A0A8J1L9R6_XENLA
Xenbase»
0.0
gramd1a.L Protein Aster-A isoform X1 Xenopus laevis
TI:8355 None
   
A0A8J1LCJ4_XENLA
Xenbase»
0.0
LOC108697225 Protein Aster-B isoform X1 Xenopus laevis
TI:8355 None
   
A0A8J1LDL8_XENLA
Xenbase»
0.0
gramd1a.S Protein Aster-A isoform X1 Xenopus laevis
TI:8355 None
   
A0A8J1M6E2_XENLA
Xenbase»
0.0
gramd1c.L GRAM domain containing 1C L homeolog isoform X1 Xenopus laevis
TI:8355 None
   
A0A8J1MBC4_XENLA
Xenbase»
0.0
MGC81152 Uncharacterized protein LOC414690 isoform X1 Xenopus laevis
TI:8355 None
   
A0BFR5_PARTE
EnsemblProtists»
0.0
GSPATT00028417001 Chromosome undetermined scaffold_104,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None
 
A0BV97_PARTE
EnsemblProtists»
0.0
GSPATT00005710001 Chromosome undetermined scaffold_13,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None
 
A0C7S1_PARTE
EnsemblProtists»
0.0
GSPATT00035969001 Chromosome undetermined scaffold_156,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None
 
A0CIT6_PARTE
EnsemblProtists»
0.0
GSPATT00007838001 Chromosome undetermined scaffold_19,
whole genome shotgun sequence		 Paramecium tetraurelia
TI:5888 None
 
A7EB90_SCLS1
EnsemblFungi»
0.0
SS1G_02576 VASt domain-containing protein Sclerotinia sclerotiorum
TI:5180 None
 
A9V2A6_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_26412 VASt domain-containing protein Monosiga brevicollis
TI:81824 None
 
D6X4Y7_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_30578 GRAM domain-containing protein Tribolium castaneum
TI:7070 None
 
E9H1J9_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_307278 GRAM domain-containing protein Daphnia pulex
TI:6669 None
 
F0ZW53_DICPU
EnsemblProtists»
0.0
DICPUDRAFT_99088 VASt domain-containing protein Dictyostelium purpureum
TI:5786 None
 
F1A542_DICPU
EnsemblProtists»
0.0
DICPUDRAFT_100061 VASt domain-containing protein Dictyostelium purpureum
TI:5786 None
 
F4PF26_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_28763 VASt domain-containing protein Batrachochytrium dendrobatidis
TI:109871 None
 
G3MZV7_BOVIN
Ensembl»
0.0
GRAMD1C GRAM domain containing 1C Bos taurus
TI:9913 None
   
Q4QEC5_LEIMA
EnsemblProtists»
0.0
LMJF_17_0730 VASt domain-containing protein Leishmania major
TI:5664 None
 
Q7QCN8_ANOGA
EnsemblMetazoa»
0.0
1273236 AGAP002732-PA Anopheles gambiae
TI:7165 None
 
Q86AF6_DICDI
dictyBase»
1.5
DDB_G0272406 VASt domain-containing protein Dictyostelium discoideum
TI:44689 None
 
A7USU0_ANOGA
EnsemblMetazoa»
0.0
5667408 AGAP002617-PA Anopheles gambiae
TI:7165 None
 
B3RS64_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_54487 GRAM domain-containing protein Trichoplax adhaerens
TI:10228 None
 
F0ZEW6_DICPU
EnsemblProtists»
0.0
DICPUDRAFT_97228 C2 domain-containing protein Dictyostelium purpureum
TI:5786 None
 
Q4Q722_LEIMA
EnsemblProtists»
0.0
LMJF_30_2720 GRAM domain-containing protein Leishmania major
TI:5664 None
 
Q4QEC6_LEIMA
EnsemblProtists»
0.0
LMJF_17_0740 VASt domain-containing protein Leishmania major
TI:5664 None
 
Q553Y9_DICDI
dictyBase»
1.5
DDB_G0275287 C2 domain-containing protein Dictyostelium discoideum
TI:44689 None
 
T1F013_HELRO
EnsemblMetazoa»
0.0
20202163 VASt domain-containing protein Helobdella robusta
TI:6412 None
 
W5M303_LEPOC
Ensembl»
0.0
GRAM domain containing 1Bb Lepisosteus oculatus
TI:7918 None
 
A0A3Q2GXW5_HORSE
Ensembl»
0.0
GRAMD1B GRAM domain containing 1B Equus caballus
TI:9796 None
   
Q8MLV6_DROME
FlyBase»
1.5
BcDNA:AT12437 AT22714p (Uncharacterized protein, isoform A) Drosophila melanogaster
TI:7227 None
 
A0A1D5QTT7_MACMU
Ensembl»
0.0
GRAMD1B GRAM domain containing 1B Macaca mulatta
TI:9544 None
   
A0A2I3TR24_PANTR
Ensembl»
0.0
GRAMD1A GRAM domain containing 1A Pan troglodytes
TI:9598 None
 
A0A803JG50_XENTR
Ensembl»
0.0
gramd1a GRAM domain containing 1A
(Protein Aster-A isoform X1)		 Xenopus tropicalis
TI:8364 None
   
A0A803JTX0_XENTR
Xenbase»
0.0
gramd1c GRAM domain-containing 1C
(Protein Aster-C isoform X1)		 Xenopus tropicalis
TI:8364 None
   
A0A803TXL7_ANOCA
Ensembl»
0.0
GRAMD1C GRAM domain containing 1C Anolis carolinensis
TI:28377 None
   
A0A803U115_ANOCA
Ensembl»
0.0
GRAM domain containing 1B Anolis carolinensis
TI:28377 None
   
A0A8I3MS15_CANLF
Ensembl»
0.0
GRAMD1A GRAM domain containing 1A Canis lupus
TI:9612 None
   
A0A8J1JX07_XENTR
Xenbase»
0.0
gramd1b Protein Aster-B isoform X1 Xenopus tropicalis
TI:8364 None
   
A0A8M9PMT0_DANRE
CTD»
0.0
gramd1bb GRAM domain-containing protein 1B isoform X1 Danio rerio
TI:7955 None
   
A0A8V0XYT1_CHICK
Ensembl»
0.0
GRAMD1C GRAM domain containing 1C Gallus gallus
TI:9031 None
   
A0A8V1A5T0_CHICK
Ensembl»
0.0
GRAMD1B GRAM domain containing 1B Gallus gallus
TI:9031 None
   
F6TRB7_MACMU
Ensembl»
0.0
GRAMD1C GRAM domain containing 1C Macaca mulatta
TI:9544 None
   
F7CCG4_MONDO
Ensembl»
0.0
GRAMD1C GRAM domain containing 1C Monodelphis domestica
TI:13616 None
   
F7G8S7_MACMU
Ensembl»
0.0
GRAMD1A GRAM domain containing 1A Macaca mulatta
TI:9544 None
   
G3QXG9_GORGO
Ensembl»
0.0
GRAMD1B GRAM domain containing 1B Gorilla gorilla
TI:9593 None
 
G3RG58_GORGO
Ensembl»
0.0
GRAMD1A GRAM domain containing 1A Gorilla gorilla
TI:9593 None
 
H2Q502_PANTR
Ensembl»
0.0
GRAMD1B GRAM domain containing 1B Pan troglodytes
TI:9598 None
 
A0A2A6CES1_PRIPA
EnsemblMetazoa»
0.0
WBGene00094567 VASt domain-containing protein Pristionchus pacificus
TI:54126 None
 
A0A8I3NCG2_CANLF
Ensembl»
0.0
GRAMD1B GRAM domain containing 1B Canis lupus
TI:9612 None
   
A0A9J7MQJ4_BRAFL
CTD»
0.0
LOC118415446 LOW QUALITY PROTEIN: protein Aster-B-like Branchiostoma floridae
TI:7739 None
   
T1G1U8_HELRO
EnsemblMetazoa»
0.0
20215046 VASt domain-containing protein Helobdella robusta
TI:6412 None
 
A2DNR1_TRIV3
VEuPathDB»
0.0
TVAG_225320 VASt domain-containing protein Trichomonas vaginalis
TI:5722 None
 
A7RTK5_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g92968 GRAM domain-containing protein Nematostella vectensis
TI:45351 None
 
A7TB47_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g248872 GRAM domain-containing protein Nematostella vectensis
TI:45351 None
 
H2LZ86_ORYLA
Ensembl»
0.0
gramd1c GRAM domain containing 1C Oryzias latipes
TI:8090 None
   
H2N1P7_ORYLA
Ensembl»
0.0
GRAM domain-containing protein Oryzias latipes
TI:8090 None
   
T1EEU0_HELRO
EnsemblMetazoa»
0.0
20195092 GRAM domain-containing protein Helobdella robusta
TI:6412 None
 
T1FPI4_HELRO
EnsemblMetazoa»
0.0
20210731 VASt domain-containing protein Helobdella robusta
TI:6412 None
 
A0A2A6C136_PRIPA
EnsemblMetazoa»
0.0
WBGene00280341 VASt domain-containing protein Pristionchus pacificus
TI:54126 None 		 
 
B7QJG6_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW014095 VASt domain-containing protein Ixodes scapularis
TI:6945 None 		 
 
E9HJ95_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_330332 VASt domain-containing protein Daphnia pulex
TI:6669 None