Collated Gene Ontology terms

Biological process: oxidoreductase activity(2025) NAD(P)H oxidase H2O2-forming activity(2025) molecular sensor activity(2025) flavin adenine dinucleotide binding(2011, 2014, 2017, 2025) thiosulfate-cyanide sulfurtransferase activity(2024) NADPH dehydrogenase activity(2025) NADH dehydrogenase activity(2025) NADP binding(2025) protein disulfide isomerase activity(2025) electron-transferring-flavoprotein dehydrogenase activity(2017)
CoA-disulfide reductase (NADPH) activity2025 rubredoxin-NAD+ reductase activity2014, 2025 oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor2014, 2025 rubredoxin-NADP+ reductase activity2011 nitrite reductase activity2025 metal ion binding2025 iron-sulfur cluster binding2025 heme binding2025 NADPH:sulfur oxidoreductase activity2025 L-amino-acid oxidase activity2025 2 iron, 2 sulfur cluster binding2025

Molecular function: cellular response to oxidative stress2017, 2025 tRNA exon ligation2025 tRNA processing2025 sulfur utilization2024 respiratory electron transport chain2025 nitric oxide catabolic process2014 nitrate assimilation2025 cellular response to nitric oxide2014 alkane catabolic process2024

Cellular component: cytoplasm2018, 2022, 2024, 2025 nucleus2017, 2018, 2024, 2025 sarcomere2017, 2025 cytosol2025

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 3/3 
Excavates: 1/4 
Harosa: 1/4 
Hacrobia: 0/0 
Plants: 1/39 
Archea: 7/8 
Bacteria: 23/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

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Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
PYRD1_HUMAN
Ensembl»
3.2
PYROXD1 tRNA ligase complex-associated NAD(P)H dehydrogenase PYROXD1 (EC
1.6.99.1) (Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1)		 Homo sapiens
TI:9606 None
 
NORW_ECOLI
EnsemblBacteria»
4.5
norW Nitric oxide reductase FlRd-NAD(+) reductase (EC
1.18.1.-) (Flavorubredoxin reductase) (FlRd-reductase) (FlavoRb reductase)		 Escherichia coli
TI:562 None
 
PYRD1_DROME
FlyBase»
0.5
Pyroxd1 tRNA ligase complex-associated NAD(P)H dehydrogenase PYROXD1 (EC
1.6.99.1) (Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1)		 Drosophila melanogaster
TI:7227 None
 
PYRD1_MOUSE
Ensembl»
2.5
Pyroxd1 tRNA ligase complex-associated NAD(P)H dehydrogenase PYROXD1 (EC
1.6.99.1) (Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1)		 Mus musculus
TI:10090 None
 
PYRD1_DANRE
ZFIN»
0.0
pyroxd1 tRNA ligase complex-associated NAD(P)H dehydrogenase PYROXD1 (EC
1.6.99.1) (Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1)		 Danio rerio
TI:7955 None
 
PYRD1_DICDI
dictyBase»
0.0
pyroxd1 tRNA ligase complex-associated NAD(P)H dehydrogenase PYROXD1 (EC
1.6.99.1) (Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1)		 Dictyostelium discoideum
TI:44689 None
 
PYRD1_RAT
RGD»
2.5
Pyroxd1 tRNA ligase complex-associated NAD(P)H dehydrogenase PYROXD1 (EC
1.6.99.1) (Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1)		 Rattus norvegicus
TI:10116 None
 
Q18213_CAEEL
WormBase»
0.0
C26D10.3 CELE_C26D10.3 Pyridine nucleotide-disulfide oxidoreductase
domain-containing protein 1		 Caenorhabditis elegans
TI:6239 None
 
A0A8V0YNN2_CHICK
Ensembl»
0.0
PYROXD1 Pyridine nucleotide-disulfide oxidoreductase
domain-containing protein 1		 Gallus gallus
TI:9031 None