Collated Gene Ontology terms

Biological process: zinc ion binding(2025) metal ion binding(2025) DNA binding(2025) RNA polymerase II cis-regulatory region sequence-specific DNA binding(2020, 2023, 2025) protease binding(2009, 2025) DNA-binding transcription factor activity(2020, 2025) transcription cis-regulatory region binding(2017) nucleic acid binding(2025) RNA polymerase II transcription regulatory region sequence-specific DNA binding(2020) DNA-binding transcription factor activity, RNA polymerase II-specific(2020)
DNA-binding transcription activator activity, RNA polymerase II-specific2025

Molecular function: regulation of transcription by RNA polymerase II2020, 2023, 2025 negative regulation of cell cycle2009, 2025 negative regulation of transcription by RNA polymerase II2020, 2025 DNA-templated transcription2025 regulation of DNA-templated transcription2017 positive regulation of transcription by RNA polymerase II2025 dendrite morphogenesis2013

Cellular component: nucleus2009, 2020, 2023, 2025 nucleoplasm2025 chromatin2020, 2025

Phylogenetic distribution

Chordates: 19/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 0/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
A0A1S4GQA1_ANOGA
EnsemblMetazoa»
0.0
Uncharacterized protein Anopheles gambiae
TI:7165 None
 
A0A1S4H5N2_ANOGA
EnsemblMetazoa»
0.0
THAP-type domain-containing protein Anopheles gambiae
TI:7165 None
 
A0A2I2YIT7_GORGO
Ensembl»
0.0
THAP domain-containing protein 5 Gorilla gorilla
TI:9593 None
 
A0A2I2Z9V4_GORGO
Ensembl»
0.0
THAP domain containing 5 Gorilla gorilla
TI:9593 None
 
A0A2I3RYG0_PANTR
Ensembl»
0.0
THAP domain-containing protein 5 Pan troglodytes
TI:9598 None
 
A0A3B3HFN0_ORYLA
Ensembl»
0.0
THAP-type domain-containing protein Oryzias latipes
TI:8090 None
   
A0A3B3HK99_ORYLA
Ensembl»
0.0
THAP-type domain-containing protein Oryzias latipes
TI:8090 None
   
A0A3B3HQN7_ORYLA
Ensembl»
0.0
THAP-type domain-containing protein Oryzias latipes
TI:8090 None
   
A0A3B3HQY2_ORYLA
Ensembl»
0.0
THAP-type domain-containing protein Oryzias latipes
TI:8090 None
   
A0A3B3HWN5_ORYLA
Ensembl»
0.0
THAP-type domain-containing protein Oryzias latipes
TI:8090 None
   
A0A3B3I4U7_ORYLA
Ensembl»
0.0
THAP-type domain-containing protein Oryzias latipes
TI:8090 None
   
A0A3B3ICU1_ORYLA
Ensembl»
0.0
THAP-type domain-containing protein Oryzias latipes
TI:8090 None
   
A0A3B3IEK7_ORYLA
Ensembl»
0.0
THAP-type domain-containing protein Oryzias latipes
TI:8090 None
   
A0A3B3INL1_ORYLA
Ensembl»
0.0
THAP-type domain-containing protein Oryzias latipes
TI:8090 None
   
A0A453YZ31_ANOGA
EnsemblMetazoa»
0.0
THAP-type domain-containing protein Anopheles gambiae
TI:7165 None
 
A0A453YZK5_ANOGA
EnsemblMetazoa»
0.0
Transposable element P transposase-like
RNase H domain-containing protein		 Anopheles gambiae
TI:7165 None 		 
 
A0A453YZL4_ANOGA
EnsemblMetazoa»
0.0
THAP-type domain-containing protein Anopheles gambiae
TI:7165 None
 
A0A453Z0R0_ANOGA
EnsemblMetazoa»
0.0
THAP-type domain-containing protein Anopheles gambiae
TI:7165 None
 
A0A7M7HMZ3_STRPU
EnsemblMetazoa»
0.0
THAP-type domain-containing protein Strongylocentrotus purpuratus
TI:7668 None
   
W5LYI8_LEPOC
Ensembl»
0.0
THAP domain-containing protein 5 Lepisosteus oculatus
TI:7918 None
   
Q7Q704_ANOGA
EnsemblMetazoa»
0.0
1276258 AGAP005573-PA Anopheles gambiae
TI:7165 None
 
T1ET39_HELRO
EnsemblMetazoa»
0.0
20199739 THAP-type domain-containing protein Helobdella robusta
TI:6412 None
 
T1F9Y3_HELRO
EnsemblMetazoa»
0.0
20205632 THAP-type domain-containing protein Helobdella robusta
TI:6412 None
 
T1FBQ7_HELRO
EnsemblMetazoa»
0.0
20206256 Uncharacterized protein Helobdella robusta
TI:6412 None 		 
 
T1FCB8_HELRO
EnsemblMetazoa»
0.0
20206467 THAP-type domain-containing protein Helobdella robusta
TI:6412 None
 
T1FDD1_HELRO
EnsemblMetazoa»
0.0
20206830 THAP-type domain-containing protein Helobdella robusta
TI:6412 None
 
T1FHI4_HELRO
EnsemblMetazoa»
0.0
20208283 Uncharacterized protein Helobdella robusta
TI:6412 None 		 
 
T1FK11_HELRO
EnsemblMetazoa»
0.0
20209160 THAP-type domain-containing protein Helobdella robusta
TI:6412 None 		 
 
T1G5R9_HELRO
EnsemblMetazoa»
0.0
20216416 THAP-type domain-containing protein Helobdella robusta
TI:6412 None
 
Q5TRK1_ANOGA
EnsemblMetazoa»
0.0
3290000 AGAP005572-PA Anopheles gambiae
TI:7165 None
 
Q5TRK0_ANOGA
EnsemblMetazoa»
0.0
3290002 AGAP005574-PA Anopheles gambiae
TI:7165 None
 
B7PXG4_IXOSC
EnsemblMetazoa»
0.0
8032791 THAP-type domain-containing protein Ixodes scapularis
TI:6945 None
 
B7PXM0_IXOSC
EnsemblMetazoa»
0.0
8032858 THAP-type domain-containing protein Ixodes scapularis
TI:6945 None
 
B7Q2S4_IXOSC
EnsemblMetazoa»
0.0
8035044 THAP-type domain-containing protein Ixodes scapularis
TI:6945 None
 
B7QKD5_IXOSC
EnsemblMetazoa»
0.0
8042562 THAP-type domain-containing protein Ixodes scapularis
TI:6945 None
 
D6WDK7_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_02756 Transposable element P transposase-like
RNase H domain-containing protein		 Tribolium castaneum
TI:7070 None 		 
 
D6X1G7_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_10989 THAP-type domain-containing protein Tribolium castaneum
TI:7070 None
 
A0A139W8N4_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_31680 THAP-type domain-containing protein Tribolium castaneum
TI:7070 None
 
A0A139WEA3_TRICA
euHCVdb»
0.0
AUGUSTUS-3.0.2_33935 THAP-type domain-containing protein Tribolium castaneum
TI:7070 None
 
Q7PXC8_ANOGA
EnsemblMetazoa»
0.0
AgaP_AGAP001340 AGAP001340-PA Anopheles gambiae
TI:7165 None
 
E9HCG2_DAPPU
euHCVdb»
0.0
DAPPUDRAFT_328078 THAP-type domain-containing protein Daphnia pulex
TI:6669 None
 
Q9VJ27_DROME
FlyBase»
3.3
Dmel\CG10431 Uncharacterized protein, isoform A
(Uncharacterized protein, isoform B)		 Drosophila melanogaster
TI:7227 None
 
B7PBW6_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW002265 THAP-type domain-containing protein Ixodes scapularis
TI:6945 None
 
B7PJ45_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW004578 THAP-type domain-containing protein Ixodes scapularis
TI:6945 None
 
B7Q678_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW021410 THAP-type domain-containing protein Ixodes scapularis
TI:6945 None
 
B7Q661_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW021686 THAP-type domain-containing protein Ixodes scapularis
TI:6945 None
 
B7QDX4_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW022713 THAP-type domain-containing protein Ixodes scapularis
TI:6945 None
 
F7A2M7_CIOIN
Ensembl»
0.0
LOC100183291 Uncharacterized LOC100183291 Ciona intestinalis
TI:7719 None
 
H2L6Z7_ORYLA
Ensembl»
0.0
LOC101158963 THAP-type domain-containing protein Oryzias latipes
TI:8090 None
   
H2M2W4_ORYLA
Ensembl»
0.0
LOC101166268 THAP domain-containing protein 5 Oryzias latipes
TI:8090 None
   
A0A1L8HWG5_XENLA
CTD»
0.0
LOC108696057 THAP domain-containing protein 1 isoform X1 Xenopus laevis
TI:8355 None
   
A0A8J1LXJ8_XENLA
CTD»
0.0
LOC108704674 THAP domain-containing protein 1 Xenopus laevis
TI:8355 None
   
A0A8I3Q8Q1_CANLF
Ensembl»
0.0
LOC119876977 THAP domain-containing protein 5 Canis lupus
TI:9612 None
   
F6U3I5_CIOIN
Ensembl»
0.0
LOC778872 Uncharacterized LOC778872 Ciona intestinalis
TI:7719 None
 
A0A286ZRG1_PIG
Ensembl»
0.0
THAP5 THAP domain-containing protein 5 Sus scrofa
TI:9823 None
   
A0A5F8GEJ3_MONDO
Ensembl»
0.0
THAP5 THAP domain-containing protein 5 Monodelphis domestica
TI:13616 None
   
A0A8V0XA52_CHICK
Ensembl»
0.0
THAP5 THAP domain-containing protein 5 Gallus gallus
TI:9031 None
   
A0A9L0RSX0_HORSE
Ensembl»
0.0
THAP5 THAP domain-containing protein 5 Equus caballus
TI:9796 None
   
A0ABI7WDM7_FELCA
Ensembl»
0.0
THAP5 THAP domain-containing protein 5 Felis catus
TI:9685 None
   
F1MH63_BOVIN
Ensembl»
0.0
THAP5 THAP domain-containing protein 5 Bos taurus
TI:9913 None
   
F7EY05_ORNAN
Ensembl»
0.0
THAP5 THAP domain-containing protein 5 Ornithorhynchus anatinus
TI:9258 None
   
F7H729_MACMU
Ensembl»
0.0
THAP5 THAP domain-containing protein 5 Macaca mulatta
TI:9544 None
   
H2QV87_PANTR
Ensembl»
0.0
THAP5 THAP domain-containing protein 5 Pan troglodytes
TI:9598 None
 
THAP5_BOVIN
CTD»
0.0
THAP5 THAP domain-containing protein 5 Bos taurus
TI:9913 None
 
THAP5_CHICK
CTD»
0.0
THAP5 THAP domain-containing protein 5 Gallus gallus
TI:9031 None
 
THAP5_HUMAN
Ensembl»
2.4
THAP5 THAP domain-containing protein 5 Homo sapiens
TI:9606 None
 
A0A3Q2HM59_HORSE
Ensembl»
0.0
THAP8 THAP domain containing 8 Equus caballus
TI:9796 None
   
A0A6I8P9V3_ORNAN
Ensembl»
0.0
THAP8 THAP domain containing 8 Ornithorhynchus anatinus
TI:9258 None
   
A0A8I3MVR2_CANLF
Ensembl»
0.0
THAP8 THAP domain containing 8 Canis lupus
TI:9612 None
   
A0A8W4FK19_PIG
Ensembl»
0.0
THAP8 THAP domain containing 8 Sus scrofa
TI:9823 None
   
F1MXZ9_BOVIN
Ensembl»
0.0
THAP8 THAP domain containing 8 Bos taurus
TI:9913 None
   
F7CAH3_MACMU
Ensembl»
0.0
THAP8 THAP domain containing 8
(THAP domain-containing protein 8)		 Macaca mulatta
TI:9544 None
 
G3SFY1_GORGO
Ensembl»
0.0
THAP8 THAP-type domain-containing protein Gorilla gorilla
TI:9593 None
 
K7AG80_PANTR
Ensembl»
0.0
THAP8 THAP domain containing 8 Pan troglodytes
TI:9598 None
 
THAP8_HUMAN
Ensembl»
0.0
THAP8 THAP domain-containing protein 8 Homo sapiens
TI:9606 None
 
B3S879_TRIAD
CTD»
0.0
TRIADDRAFT_60440 THAP-type domain-containing protein Trichoplax adhaerens
TI:10228 None
 
A0A6I8S2A9_XENTR
Xenbase»
0.0
XB5721690 Uncharacterized XB5721690 (Uncharacterized
protein LOC100497555 isoform X1)		 Xenopus tropicalis
TI:8364 None 		     
A0A1L8F8P8_XENLA
Xenbase»
0.0
XB5721690.L Uncharacterized protein XB5721690.L Xenopus laevis
TI:8355 None 		     
A0A1L8F3R9_XENLA
Xenbase»
0.0
XB5721690.S Uncharacterized protein XB5721690.S Xenopus laevis
TI:8355 None 		     
A0A8J0QNH9_XENTR
Xenbase»
0.0
XB5728948 THAP domain-containing protein 1 Xenopus tropicalis
TI:8364 None
   
A0A0R4INZ0_DANRE
ZFIN»
1.5
si:dkey-228b2.6 Si:dkey-228b2.6 (Uncharacterized
protein LOC563918)		 Danio rerio
TI:7955 None
 
A0A803T2Z9_ANOCA
Ensembl»
0.0
thap5 THAP domain-containing protein 5 Anolis carolinensis
TI:28377 None
   
A0A8J0QMD4_XENTR
Xenbase»
0.0
thap5 THAP domain-containing protein 5 Xenopus tropicalis
TI:8364 None
   
THAP5_XENLA
Xenbase»
0.0
thap5 THAP domain-containing protein 5 Xenopus laevis
TI:8355 None
 
A0A8J0UUX1_XENLA
Xenbase»
0.0
thap5.S THAP domain-containing protein 5 Xenopus laevis
TI:8355 None
   
H9G6G7_ANOCA
Ensembl»
0.0
thap8 THAP-type domain-containing protein Anolis carolinensis
TI:28377 None