Collated Gene Ontology terms

Biological process: transcription elongation factor activity(2025) structural constituent of skin epidermis(2023, 2025) RNA polymerase II complex binding(2023, 2025) structural constituent of tooth enamel(2003) identical protein binding(2008)

Molecular function: transcription elongation by RNA polymerase II2025 microtubule anchoring at centrosome2017, 2024, 2025 intracellular signal transduction2011, 2025 maintenance of ER location2006, 2024, 2025 transcription initiation at RNA polymerase II promoter2024, 2025 intracellular protein localization2017, 2025 biomineral tissue development2025 odontogenesis2003 bone mineralization2003

Cellular component: I band2011, 2024, 2025 RNA polymerase II, core complex2020, 2024, 2025 nucleus2024, 2025 centriole2017, 2024, 2025 DNA-directed RNA polymerase complex2025 transcription preinitiation complex2023, 2025 nuclear envelope2010, 2025 cytoplasmic side of plasma membrane2023, 2025 cytoplasm2010, 2025 cortical actin cytoskeleton2011, 2025
centriolar subdistal appendage2017, 2025 neuronal cell body2006, 2025 extracellular region2003, 2025 cytoskeleton2011, 2025 plasma membrane2025 anchoring junction2025 Z disc2025 membrane2011, 2025

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 0/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 1/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
CCD68_HUMAN
Ensembl»
2.9
CCDC68 Coiled-coil domain-containing protein 68 (Cutaneous T-cell
lymphoma-associated antigen se57-1) (CTCL-associated antigen se57-1)		 Homo sapiens
TI:9606 None
 
GRL1A_HUMAN
Ensembl»
2.9
POLR2M DNA-directed RNA polymerase II subunit GRINL1A (DNA-directed RNA
polymerase II subunit M) (Glutamate receptor-like protein 1A)		 Homo sapiens
TI:9606 None
 
GRL1A_MOUSE
Ensembl»
2.8
Polr2m DNA-directed RNA polymerase II subunit GRINL1A (DNA-directed RNA
polymerase II subunit M) (Glutamate receptor-like protein 1A)		 Mus musculus
TI:10090 None
 
TUFT1_HUMAN
Ensembl»
2.6
TUFT1 Tuftelin Homo sapiens
TI:9606 None
 
GRL1A_RAT
RGD»
2.5
Polr2m DNA-directed RNA polymerase II subunit GRINL1A (DNA-directed RNA
polymerase II subunit M) (Glutamate receptor-like protein 1A)		 Rattus norvegicus
TI:10116 None
 
MYZAP_MOUSE
Ensembl»
1.3
Myzap Myocardial zonula adherens protein Mus musculus
TI:10090 None
 
MYZAP_RAT
RGD»
1.0
Myzap Myocardial zonula adherens protein Rattus norvegicus
TI:10116 None
 
TUFT1_MOUSE
Ensembl»
1.0
Tuft1 Tuftelin Mus musculus
TI:10090 None
 
Q9VDY6_DROME
FlyBase»
0.6
Polr2M RNA polymerase II subunit M Drosophila melanogaster
TI:7227 None
 
A0A8I5Y0E9_RAT
RGD»
0.5
Ccdc68 Coiled-coil domain containing 68 Rattus norvegicus
TI:10116 None
   
A0ABK0LXR5_RAT
Ensembl»
0.5
Myzap Myocardial zonula adherens protein Rattus norvegicus
TI:10116 None
   
CCD68_MOUSE
Ensembl»
0.5
Ccdc68 Coiled-coil domain-containing protein 68 Mus musculus
TI:10090 None
 
MYZAP_HUMAN
Ensembl»
0.5
MYZAP Myocardial zonula adherens protein
(GRINL1A upstream protein) (Gup)		 Homo sapiens
TI:9606 None
 
A0A0G2K7T4_RAT
RGD»
0.0
Tuft1 Tuftelin 1 Rattus norvegicus
TI:10116 None
   
A0A1L8F570_XENLA
Xenbase»
0.0
tuft1.S Tuftelin Xenopus laevis
TI:8355 None
   
A0A1L8FD99_XENLA
CTD»
0.0
tuft1.L Tuftelin isoform X1 Xenopus laevis
TI:8355 None
   
A0A1L8H0C6_XENLA
CTD»
0.0
LOC108711365 DNA-directed RNA polymerase II subunit GRINL1A Xenopus laevis
TI:8355 None
   
A0A1L8HRZ5_XENLA
Xenbase»
0.0
ccdc68.S Coiled-coil domain-containing protein 68 Xenopus laevis
TI:8355 None
   
A0A1L8I2P3_XENLA
Xenbase»
0.0
ccdc68.L Coiled-coil domain-containing protein
68 isoform X1		 Xenopus laevis
TI:8355 None
   
A0A2I3SBP4_PANTR
Ensembl»
0.0
DNA-directed RNA polymerase II subunit GRINL1A (DNA-directed RNA
polymerase II subunit M) (Glutamate receptor-like protein 1A)		 Pan troglodytes
TI:9598 None
 
A0A2I3TJD0_PANTR
Ensembl»
0.0
POLR2M RNA polymerase II subunit M Pan troglodytes
TI:9598 None
 
A0A3Q1MGN7_BOVIN
Ensembl»
0.0
TUFT1 Tuftelin 1 Bos taurus
TI:9913 None 		     
A0A3Q2H7R7_HORSE
Ensembl»
0.0
LOC100630725 DNA-directed RNA polymerase II subunit GRINL1A (DNA-directed RNA
polymerase II subunit M) (Glutamate receptor-like protein 1A)		 Equus caballus
TI:9796 None
   
A0A3Q2LTA6_HORSE
Ensembl»
0.0
LOC111772353 DNA-directed RNA polymerase II subunit GRINL1A (DNA-directed RNA
polymerase II subunit M) (Glutamate receptor-like protein 1A)		 Equus caballus
TI:9796 None
   
A0A3Q2TW24_CHICK
Ensembl»
0.0
MYZAP Myocardial zonula adherens protein Gallus gallus
TI:9031 None 		     
A0A4X1W2Q2_PIG
Ensembl»
0.0
TUFT1 Tuftelin 1 Sus scrofa
TI:9823 None
   
A0A5F8G3S3_MONDO
Ensembl»
0.0
CCDC68 Coiled-coil domain containing 68 Monodelphis domestica
TI:13616 None
   
A0A6I8N790_ORNAN
Ensembl»
0.0
DNA-directed RNA polymerase II subunit GRINL1A (DNA-directed RNA
polymerase II subunit M) (Glutamate receptor-like protein 1A)		 Ornithorhynchus anatinus
TI:9258 None
   
A0A6I8R4D2_XENTR
Xenbase»
0.0
polr2m Protein GRINL1A (RNA polymerase II subunit M) Xenopus tropicalis
TI:8364 None
   
A0A6I8RT14_XENTR
Xenbase»
0.0
tuft1 Tuftelin 1 (Tuftelin isoform X1) Xenopus tropicalis
TI:8364 None
   
A0A7M7NCH4_STRPU
EnsemblMetazoa»
0.0
Uncharacterized protein Strongylocentrotus purpuratus
TI:7668 None
   
A0A8D0RNR0_PIG
Ensembl»
0.0
POLR2M DNA-directed RNA polymerase II subunit GRINL1A (DNA-directed RNA
polymerase II subunit M) (Glutamate receptor-like protein 1A)		 Sus scrofa
TI:9823 None
   
A0A8I3MLB2_CANLF
Ensembl»
0.0
CCDC68 Coiled-coil domain containing 68 Canis lupus
TI:9612 None
   
A0A8I3PGE2_CANLF
Ensembl»
0.0
TUFT1 Tuftelin 1 Canis lupus
TI:9612 None 		     
A0A8I3QLZ9_CANLF
Ensembl»
0.0
MYZAP DNA-directed RNA polymerase II subunit GRINL1A (DNA-directed RNA
polymerase II subunit M) (Glutamate receptor-like protein 1A)		 Canis lupus
TI:9612 None
   
A0A8J0UJY7_XENLA
CTD»
0.0
LOC108711364 Myocardial zonula adherens protein Xenopus laevis
TI:8355 None
   
A0A8J0UVN8_XENLA
CTD»
0.0
LOC108712935 Myocardial zonula adherens protein isoform X2 Xenopus laevis
TI:8355 None
   
A0A8N7TAE9_DANRE
ZFIN»
0.0
myzap Myocardial zonula adherens protein isoform X1 Danio rerio
TI:7955 None 		     
A0A8V0ZKV7_CHICK
Ensembl»
0.0
DNA-directed RNA polymerase II subunit GRINL1A (DNA-directed RNA
polymerase II subunit M) (Glutamate receptor-like protein 1A)		 Gallus gallus
TI:9031 None
   
A0A8V1A6P7_CHICK
Ensembl»
0.0
TUFT1 Tuftelin 1 Gallus gallus
TI:9031 None
   
A0A9J7MG19_BRAFL
euHCVdb»
0.0
LOC118409629 Uncharacterized protein LOC118409629 Branchiostoma floridae
TI:7739 None
   
A0A9L0RLQ2_HORSE
Ensembl»
0.0
CCDC68 Coiled-coil domain containing 68 Equus caballus
TI:9796 None 		     
A0ABI7XZB7_FELCA
Ensembl»
0.0
POLR2M DNA-directed RNA polymerase II subunit GRINL1A (DNA-directed RNA
polymerase II subunit M) (Glutamate receptor-like protein 1A)		 Felis catus
TI:9685 None
   
A0ABI7Y0X4_FELCA
Ensembl»
0.0
MYZAP Myocardial zonula adherens protein Felis catus
TI:9685 None 		     
A0ABI7Y1T3_FELCA
Ensembl»
0.0
CCDC68 Coiled-coil domain containing 68 Felis catus
TI:9685 None 		     
A0ABI8AFC6_FELCA
Ensembl»
0.0
TUFT1 Tuftelin 1 Felis catus
TI:9685 None 		     
A0ABK0L6P7_RAT
Ensembl»
0.0
LOC134483254 DNA-directed RNA polymerase II subunit GRINL1A (DNA-directed RNA
polymerase II subunit M) (Glutamate receptor-like protein 1A)		 Rattus norvegicus
TI:10116 None
   
A0ABK0LGF0_RAT
Ensembl»
0.0
LOC134483171 DNA-directed RNA polymerase II subunit GRINL1A (DNA-directed RNA
polymerase II subunit M) (Glutamate receptor-like protein 1A)		 Rattus norvegicus
TI:10116 None
   
A0ABK0LH87_RAT
Ensembl»
0.0
DNA-directed RNA polymerase II subunit GRINL1A (DNA-directed RNA
polymerase II subunit M) (Glutamate receptor-like protein 1A)		 Rattus norvegicus
TI:10116 None
   
A0ABK0LUM8_RAT
Ensembl»
0.0
LOC134483601 DNA-directed RNA polymerase II subunit GRINL1A (DNA-directed RNA
polymerase II subunit M) (Glutamate receptor-like protein 1A)		 Rattus norvegicus
TI:10116 None
   
A0ABK0LUN2_RAT
Ensembl»
0.0
LOC134483124 DNA-directed RNA polymerase II subunit GRINL1A (DNA-directed RNA
polymerase II subunit M) (Glutamate receptor-like protein 1A)		 Rattus norvegicus
TI:10116 None
   
A0JML6_DANRE
ZFIN»
0.0
tuft1a Tuftelin 1a (Zgc:153955) Danio rerio
TI:7955 None 		 
 
A7RS76_NEMVE
neXtProt»
0.0
NEMVEDRAFT_v1g201348 Uncharacterized protein Nematostella vectensis
TI:45351 None
 
E1BJG8_BOVIN
Ensembl»
0.0
CCDC68 Coiled-coil domain containing 68 Bos taurus
TI:9913 None
   
F1N2J6_BOVIN
Ensembl»
0.0
MYZAP Myocardial zonula adherens protein Bos taurus
TI:9913 None
   
F1Q864_DANRE
ZFIN»
0.0
polr2m Protein GRINL1A (RNA polymerase II subunit M) Danio rerio
TI:7955 None
 
F1RZH1_PIG
Ensembl»
0.0
MYZAP Myocardial zonula adherens protein Sus scrofa
TI:9823 None
 
F1S1Z2_PIG
Ensembl»
0.0
CCDC68 Coiled-coil domain containing 68 (Coiled-coil
domain-containing protein 68 isoform X1)		 Sus scrofa
TI:9823 None
 
F6SNR2_ORNAN
Ensembl»
0.0
MYZAP Myocardial zonula adherens protein Ornithorhynchus anatinus
TI:9258 None 		     
F6ZH40_HORSE
Ensembl»
0.0
TUFT1 Tuftelin 1 Equus caballus
TI:9796 None
   
F7AKE3_MONDO
Ensembl»
0.0
MYZAP Myocardial zonula adherens protein Monodelphis domestica
TI:13616 None
   
F7C8M2_ORNAN
Ensembl»
0.0
TUFT1 Tuftelin 1 Ornithorhynchus anatinus
TI:9258 None
   
F7CH25_HORSE
Ensembl»
0.0
LOC111772352 Myocardial zonula adherens protein Equus caballus
TI:9796 None
   
F7D1R4_MACMU
Ensembl»
0.0
TUFT1 Tuftelin 1 (Tuftelin isoform 2) Macaca mulatta
TI:9544 None 		 
 
F7DXR1_MACMU
Ensembl»
0.0
POLR2M DNA-directed RNA polymerase II subunit GRINL1A (DNA-directed RNA
polymerase II subunit M) (Glutamate receptor-like protein 1A)		 Macaca mulatta
TI:9544 None
   
F7E4J3_MACMU
Ensembl»
0.0
CCDC68 Coiled-coil domain containing 68 Macaca mulatta
TI:9544 None
   
F7ETY5_MONDO
Ensembl»
0.0
TUFT1 Tuftelin 1 Monodelphis domestica
TI:13616 None
   
F7GET9_MONDO
Ensembl»
0.0
DNA-directed RNA polymerase II subunit GRINL1A (DNA-directed RNA
polymerase II subunit M) (Glutamate receptor-like protein 1A)		 Monodelphis domestica
TI:13616 None
   
G3QY68_GORGO
Ensembl»
0.0
TUFT1 Tuftelin 1 Gorilla gorilla
TI:9593 None 		 
 
G3R8W5_GORGO
Ensembl»
0.0
POLR2M Myocardial zonula adherens protein Gorilla gorilla
TI:9593 None
 
G3RMR8_GORGO
Ensembl»
0.0
CCDC68 Coiled-coil domain containing 68 Gorilla gorilla
TI:9593 None
 
GRL1A_BOVIN
Ensembl»
0.0
POLR2M DNA-directed RNA polymerase II subunit GRINL1A (DNA-directed RNA polymerase II
subunit M) (GRINL1A downstream protein 1) (Gdown1) (Glutamate receptor-like protein 1A)		 Bos taurus
TI:9913 None
 
H2L464_ORYLA
Ensembl»
0.0
tuft1b Tuftelin 1b Oryzias latipes
TI:8090 None 		     
H2LWK6_ORYLA
Ensembl»
0.0
MYZAP Myocardial zonula adherens protein Oryzias latipes
TI:8090 None 		     
H2LWK7_ORYLA
Ensembl»
0.0
POLR2M RNA polymerase II subunit M Oryzias latipes
TI:8090 None
   
H2M121_ORYLA
Ensembl»
0.0
tuft1a Tuftelin 1a Oryzias latipes
TI:8090 None 		     
H2QEK4_PANTR
Ensembl»
0.0
CCDC68 Coiled-coil domain containing 68 Pan troglodytes
TI:9598 None
 
H8Y6P7_HUMAN
Ensembl»
0.0
GCOM1 DNA-directed RNA polymerase II subunit GRINL1A (DNA-directed RNA
polymerase II subunit M) (Glutamate receptor-like protein 1A)		 Homo sapiens
TI:9606 None
 
H9GEF6_ANOCA
Ensembl»
0.0
CCDC68 Coiled-coil domain containing 68 Anolis carolinensis
TI:28377 None
   
H9GI41_ANOCA
Ensembl»
0.0
Uncharacterized protein Anolis carolinensis
TI:28377 None
   
H9GQI8_ANOCA
Ensembl»
0.0
POLR2M DNA-directed RNA polymerase II subunit GRINL1A (DNA-directed RNA
polymerase II subunit M) (Glutamate receptor-like protein 1A)		 Anolis carolinensis
TI:28377 None
   
K7DJ59_PANTR
Ensembl»
0.0
TUFT1 Tuftelin 1 Pan troglodytes
TI:9598 None 		 
 
K7EDT1_ORNAN
Ensembl»
0.0
CCDC68 Coiled-coil domain containing 68 Ornithorhynchus anatinus
TI:9258 None
   
K9J7U2_XENTR
Xenbase»
0.0
ccdc68 Coiled-coil domain containing 68 (Coiled-coil
domain-containing protein 68 isoform X1)		 Xenopus tropicalis
TI:8364 None
   
MYZAP_XENTR
Ensembl»
0.0
myzap Myocardial zonula adherens protein Xenopus tropicalis
TI:8364 None
 
Q1L8T4_DANRE
ZFIN»
0.0
tuft1b Tuftelin 1b Danio rerio
TI:7955 None 		 
 
TUFT1_BOVIN
Ensembl»
0.0
TUFT1 Tuftelin (Enamelin) Bos taurus
TI:9913 None
 
TUFT1_PIG
euHCVdb»
0.0
TUFT1 Tuftelin Sus scrofa
TI:9823 None
 
W5M6Z9_LEPOC
Ensembl»
0.0
Coiled-coil domain containing 68 Lepisosteus oculatus
TI:7918 None 		 
 
W5N7W8_LEPOC
Ensembl»
0.0
Myocardial zonula adherens protein Lepisosteus oculatus
TI:7918 None