Collated Gene Ontology terms

Biological process: cysteine-type endopeptidase inhibitor activity involved in apoptotic process(2007, 2017, 2023) identical protein binding(2023) phosphatidylinositol transfer activity(2015, 2020, 2023) phosphatidylinositol binding(2015, 2023) small molecule binding(2022) molecular sequestering activity(2022)

Molecular function: regulation of apoptotic process2023 negative regulation of inflammatory response2012, 2017, 2023 negative regulation of T cell activation2012, 2017, 2023 negative regulation of TOR signaling2014, 2017, 2023 positive regulation of apoptotic process2017, 2023 T cell activation2012, 2023 innate immune response2023 immune system process2023 positive regulation of ERK1 and ERK2 cascade2015, 2023 phospholipid transport2015, 2023
intermembrane lipid transfer2023 apoptotic process2023 lipid transport2023 defense response to Gram-positive bacterium2013 salivary gland morphogenesis2015 regulation of microtubule cytoskeleton organization2015 regulation of autophagy2015 positive regulation of JNK cascade2015 phospholipid metabolic process2023 negative regulation of apoptotic process2003

Cellular component: cytoplasm2007, 2012, 2014, 2015, 2017, 2023 nucleoplasm2023 cytosol2016, 2023 plasma membrane2015, 2023 nucleus2023 lysosome2023 membrane2023 cytoskeleton2023 cell projection2015

Phylogenetic distribution

Chordates: 20/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 1/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 0 2 4 6 8 10 Knownness

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
TFP8L_DROME
FlyBase»
4.2
sigmar Protein salivary glands marred (Tumor necrosis factor alpha-induced
protein 8-like protein) (TNF alpha-induced protein 8-like protein)		 Drosophila melanogaster
TI:7227 None
 
A0A0G2K2P3_RAT
RGD»
3.0
Tnfaip8 TNF alpha induced protein 8 Rattus norvegicus
TI:10116 None
   
A0A8I5ZY03_RAT
RGD»
1.5
Tnfaip8l1 TNF alpha induced protein 8 like 1 Rattus norvegicus
TI:10116 None
   
F1NZ26_CHICK
Ensembl»
0.5
TNFAIP8L1 TNF alpha induced protein 8 like 1 Gallus gallus
TI:9031 None
   
A0A3Q3AZP2_CHICK
Ensembl»
0.0
TNFAIP8L3 TNF alpha induced protein 8 like 3 Gallus gallus
TI:9031 None
   
F1LX20_RAT
RGD»
2.0
Tnfaip8l3 TNF alpha induced protein 8 like 3 Rattus norvegicus
TI:10116 None
   
TFIP8_CHICK
Ensembl»
1.5
TNFAIP8 Tumor necrosis factor alpha-induced protein
8 (TNF alpha-induced protein 8)		 Gallus gallus
TI:9031 None
 
TFIP8_MOUSE
Ensembl»
4.9
Tnfaip8 Tumor necrosis factor alpha-induced protein
8 (TNF alpha-induced protein 8)		 Mus musculus
TI:10090 None
 
TFIP8_HUMAN
Ensembl»
3.0
TNFAIP8 Tumor necrosis factor alpha-induced protein 8 (TNF alpha-induced protein 8) (Head and neck
tumor and metastasis-related protein) (MDC-3.13) (NF-kappa-B-inducible DED-containing protein) (NDED) (SCC-S2) (TNF-induced protein GG2-1)		 Homo sapiens
TI:9606 None
 
TP8L1_CHICK
CTD»
1.0
TNFAIP8L1 Tumor necrosis factor alpha-induced protein 8-like protein 1 (TIPE1)
(TNF alpha-induced protein 8-like protein 1) (TNFAIP8-like protein 1)		 Gallus gallus
TI:9031 None
 
TP8L1_DANRE
ZFIN»
0.5
tnfaip8l1 Tumor necrosis factor alpha-induced protein 8-like protein 1 (TIPE1)
(TNF alpha-induced protein 8-like protein 1) (TNFAIP8-like protein 1)		 Danio rerio
TI:7955 None
 
TP8L1_HUMAN
Ensembl»
1.8
TNFAIP8L1 Tumor necrosis factor alpha-induced protein 8-like protein 1 (TIPE1) (TNF alpha-induced
protein 8-like protein 1) (TNFAIP8-like protein 1) (Oxidative stress-regulated gene-beta) (Oxy-beta)		 Homo sapiens
TI:9606 None
 
TP8L1_MOUSE
Ensembl»
1.8
Tnfaip8l1 Tumor necrosis factor alpha-induced protein 8-like protein 1 (TIPE1) (TNF alpha-induced
protein 8-like protein 1) (TNFAIP8-like protein 1) (Oxidative stress regulated gene-beta) (Oxy-beta)		 Mus musculus
TI:10090 None
 
TP8L2_MOUSE
Ensembl»
3.4
Tnfaip8l2 Tumor necrosis factor alpha-induced protein 8-like protein 2 (TIPE2)
(TNF alpha-induced protein 8-like protein 2) (TNFAIP8-like protein 2)		 Mus musculus
TI:10090 None
 
TP8L2_RAT
RGD»
2.5
Tnfaip8l2 Tumor necrosis factor alpha-induced protein 8-like protein 2 (TIPE2)
(TNF alpha-induced protein 8-like protein 2) (TNFAIP8-like protein 2)		 Rattus norvegicus
TI:10116 None
 
TP8L2_HUMAN
Ensembl»
1.0
TNFAIP8L2 Tumor necrosis factor alpha-induced protein 8-like protein 2 (TIPE2) (TNF alpha-induced
protein 8-like protein 2) (TNFAIP8-like protein 2) (Inflammation factor protein 20)		 Homo sapiens
TI:9606 None
 
TP8L3_DANRE
ZFIN»
0.0
tnfaip8l3 Tumor necrosis factor alpha-induced protein 8-like protein 3
(TNF alpha-induced protein 8-like protein 3) (TNFAIP8-like protein 3)		 Danio rerio
TI:7955 None
 
TP8L3_HUMAN
Ensembl»
3.8
TNFAIP8L3 Tumor necrosis factor alpha-induced protein 8-like protein 3
(TNF alpha-induced protein 8-like protein 3) (TNFAIP8-like protein 3)		 Homo sapiens
TI:9606 None
 
TP8L3_MOUSE
Ensembl»
3.2
Tnfaip8l3 Tumor necrosis factor alpha-induced protein 8-like protein 3
(TNF alpha-induced protein 8-like protein 3) (TNFAIP8-like protein 3)		 Mus musculus
TI:10090 None
 
TPL2A_DANRE
ZFIN»
0.0
tnfaip8l2a Tumor necrosis factor, alpha-induced protein 8-like protein 2 A (TIPE2 A)
(TNF alpha-induced protein 8-like protein 2 A) (TNFAIP8-like protein 2 A)		 Danio rerio
TI:7955 None
 
TPL2B_DANRE
ZFIN»
0.0
tnfaip8l2b Tumor necrosis factor, alpha-induced protein 8-like protein 2 B (TIPE2 B)
(TNF alpha-induced protein 8-like protein 2 B) (TNFAIP8-like protein 2 B)		 Danio rerio
TI:7955 None