Collated Gene Ontology terms

Biological process: cysteine-type endopeptidase inhibitor activity involved in apoptotic process(2007, 2017, 2024) identical protein binding(2024) phosphatidylinositol transfer activity(2015, 2020, 2024) phosphatidylinositol binding(2015, 2024) small molecule binding(2022) molecular sequestering activity(2022)

Molecular function: regulation of apoptotic process2024 negative regulation of inflammatory response2012, 2017, 2024 negative regulation of T cell activation2012, 2017, 2024 negative regulation of TOR signaling2014, 2017, 2024 innate immune response2024 apoptotic process2024 positive regulation of apoptotic process2017, 2024 T cell activation2012, 2024 positive regulation of ERK1 and ERK2 cascade2015, 2024 phospholipid transport2015, 2024
intermembrane lipid transfer2024 lipid transport2024 defense response to Gram-positive bacterium2013 salivary gland morphogenesis2015 regulation of microtubule cytoskeleton organization2015 regulation of autophagy2015 positive regulation of JNK cascade2015 phospholipid metabolic process2024 negative regulation of apoptotic process2003

Cellular component: cytoplasm2007, 2012, 2014, 2015, 2017, 2024 nucleoplasm2023, 2024 cytosol2016, 2023, 2024 plasma membrane2015, 2024 nucleus2024 lysosome2024 cytoskeleton2024 cell projection2015

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 1/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 1/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
TFP8L_DROME
FlyBase»
4.2
sigmar Protein salivary glands marred (Tumor necrosis factor alpha-induced
protein 8-like protein) (TNF alpha-induced protein 8-like protein)		 Drosophila melanogaster
TI:7227 None
 
A0A0G2K2P3_RAT
RGD»
3.0
Tnfaip8 TNF alpha induced protein 8 Rattus norvegicus
TI:10116 None
   
A0A8I5ZY03_RAT
RGD»
1.5
Tnfaip8l1 TNF alpha induced protein 8 like 1 Rattus norvegicus
TI:10116 None
   
F1NZ26_CHICK
Ensembl»
0.5
TNFAIP8L1 TNF alpha induced protein 8 like 1 Gallus gallus
TI:9031 None
   
A0A3Q3AZP2_CHICK
Ensembl»
0.0
TNFAIP8L3 TNF alpha induced protein 8 like 3 Gallus gallus
TI:9031 None
   
F1LX20_RAT
RGD»
2.0
Tnfaip8l3 TNF alpha induced protein 8 like 3 Rattus norvegicus
TI:10116 None
   
TFIP8_CHICK
Ensembl»
1.5
TNFAIP8 Tumor necrosis factor alpha-induced protein
8 (TNF alpha-induced protein 8)		 Gallus gallus
TI:9031 None
 
TFIP8_MOUSE
Ensembl»
3.4
Tnfaip8 Tumor necrosis factor alpha-induced protein
8 (TNF alpha-induced protein 8)		 Mus musculus
TI:10090 None
 
TFIP8_HUMAN
Ensembl»
3.0
TNFAIP8 Tumor necrosis factor alpha-induced protein 8 (TNF alpha-induced protein 8) (Head and neck
tumor and metastasis-related protein) (MDC-3.13) (NF-kappa-B-inducible DED-containing protein) (NDED) (SCC-S2) (TNF-induced protein GG2-1)		 Homo sapiens
TI:9606 None
 
TP8L1_CHICK
CTD»
1.0
TNFAIP8L1 Tumor necrosis factor alpha-induced protein 8-like protein 1 (TIPE1)
(TNF alpha-induced protein 8-like protein 1) (TNFAIP8-like protein 1)		 Gallus gallus
TI:9031 None
 
TP8L1_DANRE
ZFIN»
0.5
tnfaip8l1 Tumor necrosis factor alpha-induced protein 8-like protein 1 (TIPE1)
(TNF alpha-induced protein 8-like protein 1) (TNFAIP8-like protein 1)		 Danio rerio
TI:7955 None
 
TP8L1_HUMAN
Ensembl»
1.8
TNFAIP8L1 Tumor necrosis factor alpha-induced protein 8-like protein 1 (TIPE1) (TNF alpha-induced
protein 8-like protein 1) (TNFAIP8-like protein 1) (Oxidative stress-regulated gene-beta) (Oxy-beta)		 Homo sapiens
TI:9606 None
 
TP8L1_MOUSE
Ensembl»
0.8
Tnfaip8l1 Tumor necrosis factor alpha-induced protein 8-like protein 1 (TIPE1) (TNF alpha-induced
protein 8-like protein 1) (TNFAIP8-like protein 1) (Oxidative stress regulated gene-beta) (Oxy-beta)		 Mus musculus
TI:10090 None
 
TP8L2_MOUSE
Ensembl»
2.4
Tnfaip8l2 Tumor necrosis factor alpha-induced protein 8-like protein 2 (TIPE2)
(TNF alpha-induced protein 8-like protein 2) (TNFAIP8-like protein 2)		 Mus musculus
TI:10090 None
 
TP8L2_RAT
RGD»
2.5
Tnfaip8l2 Tumor necrosis factor alpha-induced protein 8-like protein 2 (TIPE2)
(TNF alpha-induced protein 8-like protein 2) (TNFAIP8-like protein 2)		 Rattus norvegicus
TI:10116 None
 
TP8L2_HUMAN
Ensembl»
1.0
TNFAIP8L2 Tumor necrosis factor alpha-induced protein 8-like protein 2 (TIPE2) (TNF alpha-induced
protein 8-like protein 2) (TNFAIP8-like protein 2) (Inflammation factor protein 20)		 Homo sapiens
TI:9606 None
 
TP8L3_DANRE
ZFIN»
0.0
tnfaip8l3 Tumor necrosis factor alpha-induced protein 8-like protein 3
(TNF alpha-induced protein 8-like protein 3) (TNFAIP8-like protein 3)		 Danio rerio
TI:7955 None
 
TP8L3_HUMAN
Ensembl»
3.8
TNFAIP8L3 Tumor necrosis factor alpha-induced protein 8-like protein 3
(TNF alpha-induced protein 8-like protein 3) (TNFAIP8-like protein 3)		 Homo sapiens
TI:9606 None
 
TP8L3_MOUSE
Ensembl»
3.2
Tnfaip8l3 Tumor necrosis factor alpha-induced protein 8-like protein 3
(TNF alpha-induced protein 8-like protein 3) (TNFAIP8-like protein 3)		 Mus musculus
TI:10090 None
 
TPL2A_DANRE
ZFIN»
0.0
tnfaip8l2a Tumor necrosis factor, alpha-induced protein 8-like protein 2 A (TIPE2 A)
(TNF alpha-induced protein 8-like protein 2 A) (TNFAIP8-like protein 2 A)		 Danio rerio
TI:7955 None
 
TPL2B_DANRE
ZFIN»
0.0
tnfaip8l2b Tumor necrosis factor, alpha-induced protein 8-like protein 2 B (TIPE2 B)
(TNF alpha-induced protein 8-like protein 2 B) (TNFAIP8-like protein 2 B)		 Danio rerio
TI:7955 None