Collated Gene Ontology terms

Biological process: protein kinase activity(2024) molecular adaptor activity(2024) ATP binding(2024)

Molecular function: retrograde transport, endosome to Golgi2013, 2017, 2024 endocytosis2009, 2017, 2024 protein localization2013, 2017, 2024 protein transport2024 apical protein localization2015, 2024 protein phosphorylation2024 piecemeal microautophagy of the nucleus2021 intracellular protein transport2006 clathrin-coated vesicle cargo loading, AP-1-mediated2020 Golgi to vacuole transport2021

Cellular component: cytosol2009, 2023, 2024 endocytic vesicle2009, 2017, 2024 nuclear speck2023, 2024 intracellular membrane-bounded organelle2023, 2024 Golgi apparatus2009, 2024 nucleus2009, 2024 cytoplasmic vesicle2024 clathrin-coated vesicle2024 membrane2014, 2024 cytoplasm2024
perinuclear region of cytoplasm2024

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 3/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 13/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
A0A0B4KGF6_DROME
FlyBase»
3.1
Dmel\CG2747 Uncharacterized protein, isoform F Drosophila melanogaster
TI:7227 None
 
A0A0R4ISV1_DANRE
ZFIN»
1.5
heatr5b HEAT repeat-containing 5B
(HEAT repeat-containing protein 5B)		 Danio rerio
TI:7955 None
 
A0A139WP21_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_04631 HEAT repeat-containing protein 5B-like Protein Tribolium castaneum
TI:7070 None
 
A0A1D5REU2_MACMU
Ensembl»
0.0
HEATR5B HEAT repeat containing 5B Macaca mulatta
TI:9544 None 		     
A0A287BPP2_PIG
Ensembl»
0.0
HEATR5B HEAT repeat containing 5B Sus scrofa
TI:9823 None
   
A0A2A6CRY3_PRIPA
EnsemblMetazoa»
0.0
WBGene00102000 Soap-1 Pristionchus pacificus
TI:54126 None
 
A0A2I2UT24_FELCA
Ensembl»
0.0
HEATR5B HEAT repeat containing 5B Felis catus
TI:9685 None
 
A0A337SQL6_FELCA
Ensembl»
0.0
HEATR5A HEAT repeat containing 5A Felis catus
TI:9685 None
 
A0A5F5PXX2_HORSE
Ensembl»
0.0
HEATR5B HEAT repeat containing 5B Equus caballus
TI:9796 None
   
A0A5F8ARR6_MACMU
Ensembl»
0.0
HEATR5A HEAT repeat containing 5A Macaca mulatta
TI:9544 None
   
A0A6I8QC90_XENTR
Xenbase»
0.0
heatr5a HEAT repeat-containing protein 5A (HEAT
repeat-containing protein 5A isoform X1)		 Xenopus tropicalis
TI:8364 None 		     
A0A7M7PWN0_STRPU
EnsemblMetazoa»
0.0
HEAT repeat-containing protein 5B Strongylocentrotus purpuratus
TI:7668 None
   
A0A803TPX7_ANOCA
Ensembl»
0.0
HEATR5A HEAT repeat containing 5A Anolis carolinensis
TI:28377 None 		     
A0A8I3NLT1_CANLF
Ensembl»
0.0
HEATR5A HEAT repeat containing 5A Canis lupus
TI:9612 None 		     
A0A8I3PDP6_CANLF
Ensembl»
0.0
HEATR5B HEAT repeat containing 5B Canis lupus
TI:9612 None
   
A0A8I6AF96_RAT
RGD»
1.5
Heatr5a HEAT repeat containing 5A Rattus norvegicus
TI:10116 None
   
A0A8I6GJQ5_RAT
RGD»
1.5
Heatr5b HEAT repeat containing 5B Rattus norvegicus
TI:10116 None
   
A0A8J0TMY3_XENLA
Xenbase»
0.0
heatr5a.L HEAT repeat-containing protein 5A isoform X1 Xenopus laevis
TI:8355 None
   
A0A8V0XMK3_CHICK
Ensembl»
0.0
HEATR5A HEAT repeat containing 5A Gallus gallus
TI:9031 None 		     
A0A8W4FMJ8_PIG
Ensembl»
0.0
HEAT repeat containing 5A Sus scrofa
TI:9823 None 		     
A0A9J7M2G1_BRAFL
CTD»
0.0
LOC118427331 HEAT repeat-containing protein 5B-like Branchiostoma floridae
TI:7739 None 		     
A7EUF0_SCLS1
EnsemblFungi»
0.0
SS1G_08957 HEAT repeat-containing protein 5B Sclerotinia sclerotiorum
TI:5180 None 		 
 
A7EUF1_SCLS1
VEuPathDB»
0.0
SS1G_08958 MMS19 nucleotide excision repair protein Sclerotinia sclerotiorum
TI:5180 None 		 
 
A7T979_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g151016 HEAT repeat-containing protein 1 Nematostella vectensis
TI:45351 None 		 
 
A8XUT0_CAEBR
WormBase»
0.0
soap-1 Protein CBG19103 Caenorhabditis briggsae
TI:6238 None
 
A9VBE0_MONBE
EnsemblProtists»
0.0
MONBRDRAFT_34393 Protein kinase domain-containing protein Monosiga brevicollis
TI:81824 None
 
B3RZ01_TRIAD
EnsemblMetazoa»
0.0
TRIADDRAFT_26322 HEAT repeat-containing protein 5B Trichoplax adhaerens
TI:10228 None
 
B5YN77_THAPS
EnsemblProtists»
0.0
THAPS_23497 DUF4042 domain-containing protein Thalassiosira pseudonana
TI:35128 None 		 
 
B6K4E8_SCHJY
EnsemblFungi»
0.0
SJAG_03504 Pof6 interacting protein Sip1 Schizosaccharomyces japonicus
TI:4897 None
 
B7PYM8_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW020278 HEAT repeat-containing protein 5B, putative Ixodes scapularis
TI:6945 None
 
E1BB26_BOVIN
Ensembl»
0.0
HEATR5B HEAT repeat containing 5B Bos taurus
TI:9913 None
   
E1BGU0_BOVIN
Ensembl»
0.0
HEATR5A HEAT repeat containing 5A Bos taurus
TI:9913 None
   
E1C8J1_CHICK
Ensembl»
1.5
HEATR5B HEAT repeat containing 5B Gallus gallus
TI:9031 None
   
E3KZY1_PUCGT
EnsemblFungi»
0.0
PGTG_15818 Uncharacterized protein Puccinia graminis
TI:5297 None
 
E9HBA8_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_112212 HEAT repeat-containing protein 5B Daphnia pulex
TI:6669 None
 
F0ZNM1_DICPU
EnsemblProtists»
0.0
DICPUDRAFT_34947 HEAT repeat-containing protein Dictyostelium purpureum
TI:5786 None
 
F1SHF7_PIG
Ensembl»
0.0
HEATR5A HEAT repeat containing 5A Sus scrofa
TI:9823 None 		     
F4NZM3_BATDJ
EnsemblBacteria»
0.0
BATDEDRAFT_34806 Uncharacterized protein Batrachochytrium dendrobatidis
TI:109871 None
 
F6Q9A6_ORNAN
Ensembl»
0.0
HEATR5A HEAT repeat containing 5A Ornithorhynchus anatinus
TI:9258 None
   
F6WHJ9_MONDO
Ensembl»
0.0
HEATR5B HEAT repeat containing 5B Monodelphis domestica
TI:13616 None
   
F6Y2G6_MONDO
Ensembl»
0.0
HEATR5A HEAT repeat containing 5A Monodelphis domestica
TI:13616 None
   
F7G406_ORNAN
Ensembl»
0.0
HEATR5B HEAT repeat containing 5B Ornithorhynchus anatinus
TI:9258 None
   
G1KHM8_ANOCA
Ensembl»
0.0
HEATR5B HEAT repeat containing 5B Anolis carolinensis
TI:28377 None
   
G3QEF3_GORGO
Ensembl»
0.0
HEATR5A HEAT repeat containing 5A Gorilla gorilla
TI:9593 None
 
G3QQP3_GORGO
Ensembl»
0.0
HEATR5B HEAT repeat containing 5B Gorilla gorilla
TI:9593 None
 
H2MAH0_ORYLA
Ensembl»
0.0
heatr5b HEAT repeat containing 5B Oryzias latipes
TI:8090 None
   
H2QHR2_PANTR
Ensembl»
0.0
HEATR5B HEAT repeat containing 5B Pan troglodytes
TI:9598 None
 
H2Y0W9_CIOIN
Ensembl»
0.0
HEAT repeat-containing protein 5B Ciona intestinalis
TI:7719 None
 
H3GHD1_PHYRM
EnsemblProtists»
0.0
Uncharacterized protein Phytophthora ramorum
TI:164328 None 		 
 
HTR5A_DANRE
ZFIN»
1.5
heatr5a HEAT repeat-containing protein 5A Danio rerio
TI:7955 None
 
HTR5A_HUMAN
Ensembl»
1.5
HEATR5A HEAT repeat-containing protein 5A Homo sapiens
TI:9606 None
 
HTR5A_MOUSE
Ensembl»
0.0
Heatr5a HEAT repeat-containing protein 5A Mus musculus
TI:10090 None 		 
 
HTR5A_XENTR
Xenbase»
0.0
heatr5a HEAT repeat-containing protein 5A Xenopus tropicalis
TI:8364 None 		 
 
HTR5B_HUMAN
Ensembl»
1.5
HEATR5B HEAT repeat-containing protein 5B Homo sapiens
TI:9606 None
 
HTR5B_MOUSE
Ensembl»
0.0
Heatr5b HEAT repeat-containing protein 5B Mus musculus
TI:10090 None
 
HTR5B_XENTR
Xenbase»
0.0
heatr5b HEAT repeat-containing protein 5B Xenopus tropicalis
TI:8364 None
 
K7CEL0_PANTR
Ensembl»
0.0
HEATR5A HEAT repeat containing 5A Pan troglodytes
TI:9598 None
 
LAA1_YEAST
SGD»
4.7
LAA1 AP-1 accessory protein LAA1
(Large AP-1 accessory protein 1)		 Saccharomyces cerevisiae
TI:4932 None
 
O01485_CAEEL
WormBase»
2.3
soap-1 HEAT repeat-containing protein 5B Caenorhabditis elegans
TI:6239 None
 
Q4V7I5_XENLA
Xenbase»
0.0
heatr5b.L MGC115675 protein
(Uncharacterized protein LOC734613)		 Xenopus laevis
TI:8355 None
 
Q4WDA7_ASPFU
EnsemblFungi»
0.0
AFUA_6G04080 HEAT repeat protein Aspergillus fumigatus
TI:746128 None
 
Q54U23_DICDI
dictyBase»
1.5
DDB_G0281353 Uncharacterized protein Dictyostelium discoideum
TI:44689 None
 
Q5A881_CANAL
EnsemblFungi»
0.0
CAALFM_CR01080WA orf19.10757 AP-1 accessory protein LAA1 Candida albicans
TI:5476 None
 
Q5AYN2_EMENI
EnsemblFungi»
0.0
ANIA_06598 HEAT repeat protein Emericella nidulans
TI:162425 None
 
Q5KER6_CRYNJ
EnsemblFungi»
0.0
CNF04530 Clathrin-coated vesicle protein, putative Cryptococcus neoformans
TI:5207 None
 
Q6CA83_YARLI
EnsemblFungi»
0.0
YALI0_D05049g YALI0D05049p Yarrowia lipolytica
TI:4952 None
 
Q7PEZ3_ANOGA
EnsemblMetazoa»
0.0
1269345 AGAP002215-PA Anopheles gambiae
TI:7165 None
 
Q7S2X7_NEUCR
EnsemblFungi»
0.0
NCU08993 HEAT repeat containing protein Neurospora crassa
TI:5141 None
 
SIP1_SCHPO
PomBase»
3.3
sip1 Pof6 interactor protein 1 Schizosaccharomyces pombe
TI:4896 None
 
T1ELN1_HELRO
EnsemblMetazoa»
0.0
20197481 HEAT repeat-containing protein 5B Helobdella robusta
TI:6412 None
 
W5MTI8_LEPOC
Ensembl»
0.0
HEAT repeat containing 5A Lepisosteus oculatus
TI:7918 None 		 
 
W5MTJ7_LEPOC
Ensembl»
0.0
HEAT repeat containing 5a Lepisosteus oculatus
TI:7918 None
 
W5NG46_LEPOC
Ensembl»
0.0
HEAT repeat containing 5B Lepisosteus oculatus
TI:7918 None