Cluster UKP07179
- CYTOCHROME C1 HEME LYASE
Standard knownness: 5.6; Custom knownness: None; Num. species: 53; Orthology database: Panther19.0; Protein members: 90
Collated Gene Ontology terms
Biological process:
holocytochrome-c synthase activity(2007, 2008, 2013, 2014, 2019, 2020, 2021, 2024)
metal ion binding(2024)
lyase activity(2024)
ATP binding(2024)
heme binding(2020, 2024)
protein kinase activity(2024)
kinase activity(2024)
eukaryotic translation initiation factor 2alpha kinase activity(2020)
protein serine/threonine kinase activity(2024)
Molecular function: cytochrome c-heme linkage2007, 2008, 2020, 2024 protein phosphorylation2024 phosphorylation2024 cytochrome c biosynthetic process2015, 2022 aerobic respiration2014 respiratory electron transport chain2024 mitochondrion organization2015 filamentous growth of a population of unicellular organisms2014 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2021 animal organ morphogenesis2003
Cellular component: mitochondrion2004, 2007, 2008, 2009, 2010, 2014, 2018, 2020, 2021, 2023, 2024 mitochondrial inner membrane2007, 2024 mitochondrial intermembrane space2004, 2013, 2024 membrane2020, 2024 cytosol2020, 2024 nucleus2024 cytoplasm2024 fungal-type cell wall2014
Phylogenetic distribution
| Chordates: | 21/21 |  |
| Echinoderms: | 0/0 | |
| Hemichordates: | 1/1 | |
| Annelids: | 1/1 | |
| Molluscs: | 0/0 | |
| Bryozoans: | 0/0 | |
| Platyhelminthes: | 0/0 | |
| Rotifers: | 0/0 | |
| Nematodes: | 2/3 | |
| Arthropods: | 5/5 | |
| Tardigrades: | 0/0 | |
| Placozoa: | 1/1 | |
| Cnidaria: | 1/1 | |
| Porifera: | 0/0 | |
| Choanoflagellates+: | 14/1 | |
| Dikarya: | 0/14 | |
| Fungi (other): | 0/1 | |
| Protozoa: | 2/3 | |
| Excavates: | 0/4 | |
| Harosa: | 3/4 | |
| Hacrobia: | 0/0 | |
| Plants: | 2/39 | |
| Archea: | 0/8 | |
| Bacteria: | 0/35 |
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Proteins
| UniProt ID Organism DB» |
Standard knownness | clustom knownness | Gene name | Description | Species [Key only] | GO terms | Seq. links | Protein domain links | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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CCHL_HUMAN Ensembl» |
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HCCS | Holocytochrome c-type synthase (EC 4.4.1.17) (Cytochrome c-type heme lyase) |
Homo sapiens TI:9606 None |
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A0A1D8PN32_CANAL EnsemblFungi» |
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CYC3 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Candida albicans TI:5476 None |
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A0A2K3CU79_CHLRE EnsemblPlants» |
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CHLRE_16g690050v5 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Chlamydomonas reinhardtii TI:3055 None |
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A0A3Q2II97_HORSE Ensembl» |
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HCCS | Holocytochrome c-type synthase (EC 4.4.1.17) |
Equus caballus TI:9796 None |
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A0A5F8GJ34_MONDO Ensembl» |
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HCCS | Holocytochrome c-type synthase (EC 4.4.1.17) |
Monodelphis domestica TI:13616 None |
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A0A6I8MZK1_ORNAN Ensembl» |
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RWDD3 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Ornithorhynchus anatinus TI:9258 None |
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A0A7M7PHX4_STRPU EnsemblMetazoa» |
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Holocytochrome c-type synthase (EC 4.4.1.17) |
Strongylocentrotus purpuratus TI:7668 None |
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A0A8I3Q0E2_CANLF Ensembl» |
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HCCS | Holocytochrome c-type synthase (EC 4.4.1.17) |
Canis lupus TI:9612 None |
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A0A8J0PYY3_XENLA Xenbase» |
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hccs.S | Holocytochrome c-type synthase (EC 4.4.1.17) |
Xenopus laevis TI:8355 None |
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A0A8J0QEM4_XENTR Xenbase» |
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hccs | Holocytochrome c-type synthase (EC 4.4.1.17) |
Xenopus tropicalis TI:8364 None |
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A0A8M2BAG4_DANRE CTD» |
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hccsa.1 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Danio rerio TI:7955 None |
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A0A8M6YUX6_DANRE CTD» |
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hccsa.2 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Danio rerio TI:7955 None |
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A0A9J7NC40_BRAFL CTD» |
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LOC118431246 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Branchiostoma floridae TI:7739 None |
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A4DA81_ASPFU EnsemblFungi» |
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AFUA_4G04600 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Aspergillus fumigatus TI:746128 None |
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A7EF66_SCLS1 EnsemblFungi» |
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SS1G_03957 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Sclerotinia sclerotiorum TI:5180 None |
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A7EHI2_SCLS1 EnsemblFungi» |
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SS1G_04774 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Sclerotinia sclerotiorum TI:5180 None |
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A7RTZ6_NEMVE EnsemblMetazoa» |
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NEMVEDRAFT_v1g228742 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Nematostella vectensis TI:45351 None |
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A8J5J2_CHLRE EnsemblPlants» |
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CHLRE_12g525700v5 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Chlamydomonas reinhardtii TI:3055 None |
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A8WT56_CAEBR WormBase» |
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cchl-1 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Caenorhabditis briggsae TI:6238 None |
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A9V6U7_MONBE EnsemblProtists» |
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MONBRDRAFT_27974 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Monosiga brevicollis TI:81824 None |
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A9VA32_MONBE EnsemblProtists» |
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MONBRDRAFT_38782 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Monosiga brevicollis TI:81824 None |
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B3S3P9_TRIAD EnsemblMetazoa» |
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TRIADDRAFT_28549 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Trichoplax adhaerens TI:10228 None |
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B5YNR0_THAPS EnsemblProtists» |
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THAPS_23599 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Thalassiosira pseudonana TI:35128 None |
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B6K3L0_SCHJY EnsemblFungi» |
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SJAG_03199 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Schizosaccharomyces japonicus TI:4897 None |
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B6K5N2_SCHJY EnsemblFungi» |
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SJAG_04008 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Schizosaccharomyces japonicus TI:4897 None |
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B7PEK0_IXOSC EnsemblMetazoa» |
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8051129 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Ixodes scapularis TI:6945 None |
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B8C628_THAPS EnsemblProtists» |
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THAPSDRAFT_28667 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Thalassiosira pseudonana TI:35128 None |
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C8VCA9_EMENI EnsemblFungi» |
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ANIA_10879 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Emericella nidulans TI:162425 None |
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CCHL_BOVIN Ensembl» |
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HCCS | Holocytochrome c-type synthase (EC 4.4.1.17) (Cytochrome c-type heme lyase) (CCHL) |
Bos taurus TI:9913 None |
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CCHL_CHICK Ensembl» |
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HCCS | Holocytochrome c-type synthase (EC 4.4.1.17) (Cytochrome c-type heme lyase) (CCHL) |
Gallus gallus TI:9031 None |
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CCHL_MOUSE Ensembl» |
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Hccs | Holocytochrome c-type synthase (EC 4.4.1.17) (Cytochrome c-type heme lyase) (CCHL) |
Mus musculus TI:10090 None |
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D3ZL85_RAT RGD» |
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Hccs | Holocytochrome c-type synthase (EC 4.4.1.17) |
Rattus norvegicus TI:10116 None |
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D6X0A1_TRICA EnsemblMetazoa» |
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AUGUSTUS-3.0.2_11725 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Tribolium castaneum TI:7070 None |
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D8SHA5_SELML EnsemblPlants» |
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SELMODRAFT_4288 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Selaginella moellendorffii TI:88036 None |
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D8TCL9_SELML EnsemblPlants» |
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SELMODRAFT_4287 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Selaginella moellendorffii TI:88036 None |
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E3JQ46_PUCGT EnsemblFungi» |
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PGTG_00085 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Puccinia graminis TI:5297 None |
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E3JT69_PUCGT EnsemblFungi» |
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PGTG_01941 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Puccinia graminis TI:5297 None |
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E9GEU5_DAPPU EnsemblMetazoa» |
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DAPPUDRAFT_302793 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Daphnia pulex TI:6669 None |
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F1A1M4_DICPU EnsemblProtists» |
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DICPUDRAFT_42199 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Dictyostelium purpureum TI:5786 None |
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F1SG16_PIG Ensembl» |
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HCCS | Holocytochrome c-type synthase (EC 4.4.1.17) |
Sus scrofa TI:9823 None |
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F4P4Q2_BATDJ EnsemblBacteria» |
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BATDEDRAFT_5095 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Batrachochytrium dendrobatidis TI:109871 None |
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F4P789_BATDJ EnsemblBacteria» |
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BATDEDRAFT_5923 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Batrachochytrium dendrobatidis TI:109871 None |
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F6S1K1_CIOIN Ensembl» |
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LOC100181858 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Ciona intestinalis TI:7719 None |
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G1KD75_ANOCA Ensembl» |
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Holocytochrome c-type synthase (EC 4.4.1.17) |
Anolis carolinensis TI:28377 None |
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G3QWL4_GORGO Ensembl» |
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HCCS | Holocytochrome c-type synthase (EC 4.4.1.17) |
Gorilla gorilla TI:9593 None |
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G7NS87_MACMU Ensembl» |
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HCCS | Holocytochrome c-type synthase (EC 4.4.1.17) |
Macaca mulatta TI:9544 None |
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H3GBQ0_PHYRM EnsemblProtists» |
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Holocytochrome c-type synthase (EC 4.4.1.17) |
Phytophthora ramorum TI:164328 None |
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K7DKZ2_PANTR Ensembl» |
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HCCS | Holocytochrome c-type synthase (EC 4.4.1.17) |
Pan troglodytes TI:9598 None |
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M3XCQ6_FELCA Ensembl» |
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HCCS | Holocytochrome c-type synthase (EC 4.4.1.17) |
Felis catus TI:9685 None |
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Q4WNV8_ASPFU EnsemblFungi» |
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AFUA_4G07120 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Aspergillus fumigatus TI:746128 None |
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Q5AMR8_CANAL EnsemblFungi» |
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CYT2 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Candida albicans TI:5476 None |
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Q5B4W5_EMENI EnsemblFungi» |
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ANIA_04415 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Emericella nidulans TI:162425 None |
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Q5KFQ2_CRYNJ EnsemblFungi» |
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CNF00970 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Cryptococcus neoformans TI:5207 None |
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Q5KQ86_CRYNJ EnsemblFungi» |
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CNA00150 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Cryptococcus neoformans TI:5207 None |
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Q6C6U2_YARLI EnsemblFungi» |
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YALI0_E06215g | Holocytochrome c-type synthase (EC 4.4.1.17) |
Yarrowia lipolytica TI:4952 None |
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Q6CC34_YARLI EnsemblFungi» |
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YALI0_C12918g | Holocytochrome c-type synthase (EC 4.4.1.17) |
Yarrowia lipolytica TI:4952 None |
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Q758Z5_ASHGO EnsemblFungi» |
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AGOS_ADR382W | Holocytochrome c-type synthase (EC 4.4.1.17) |
Ashbya gossypii TI:33169 None |
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Q759W8_ASHGO EnsemblFungi» |
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AGOS_ADR154W | Holocytochrome c-type synthase (EC 4.4.1.17) |
Ashbya gossypii TI:33169 None |
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Q7QFU4_ANOGA EnsemblMetazoa» |
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1271579 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Anopheles gambiae TI:7165 None |
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Q7S3Z2_NEUCR EnsemblFungi» |
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NCU08138 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Neurospora crassa TI:5141 None |
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Q7ZTL8_XENLA Xenbase» |
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hccs.L | Holocytochrome c-type synthase (EC 4.4.1.17) |
Xenopus laevis TI:8355 None |
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Q803H2_DANRE ZFIN» |
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hccs | Holocytochrome c-type synthase (EC 4.4.1.17) |
Danio rerio TI:7955 None |
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Q8I5H1_PLAF7 EnsemblProtists» |
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PF3D7_1224600 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Plasmodium falciparum TI:5833 None |
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Q8I609_PLAF7 EnsemblProtists» |
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PF3D7_1203600 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Plasmodium falciparum TI:5833 None |
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Q9VD55_DROME FlyBase» |
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Cchl | Holocytochrome c-type synthase (EC 4.4.1.17) |
Drosophila melanogaster TI:7227 None |
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T1EGB5_HELRO EnsemblMetazoa» |
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20195617 | Holocytochrome c-type synthase (EC 4.4.1.17) |
Helobdella robusta TI:6412 None |
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W5MNJ5_LEPOC Ensembl» |
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Holocytochrome c-type synthase (EC 4.4.1.17) |
Lepisosteus oculatus TI:7918 None |
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CCHL_NEUCR EnsemblFungi» |
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cyt-2 | Holocytochrome-c synthase (EC 4.4.1.17) (Cytochrome c heme lyase) (CCHL) |
Neurospora crassa TI:5141 None |
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CCHL_YEAST SGD» |
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CYC3 | Holocytochrome-c synthase (EC 4.4.1.17) (Cytochrome c heme lyase) (CCHL) |
Saccharomyces cerevisiae TI:4932 None |
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CYT2_YEAST SGD» |
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CYT2 | Holocytochrome-c1 synthase (EC 4.4.1.17) (Cytochrome c1 heme lyase) (CC1HL) |
Saccharomyces cerevisiae TI:4932 None |
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CCHL_CAEEL WormBase» |
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cchl-1 | Probable holocytochrome-c-type synthase (EC 4.4.1.17) (Cytochrome c-type heme lyase) (CCHL) |
Caenorhabditis elegans TI:6239 None |
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CCHL_DICDI dictyBase» |
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cchl | Probable holocytochrome-c-type synthase (EC 4.4.1.17) (Cytochrome c-type heme lyase) (CCHL) |
Dictyostelium discoideum TI:44689 None |
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CCHL_SCHPO PomBase» |
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SPBC26H8.12 | Putative holocytochrome-c synthase (EC 4.4.1.17) (Cytochrome c heme lyase) (CCHL) |
Schizosaccharomyces pombe TI:4896 None |
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YE42_SCHPO PomBase» |
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SPAC24C9.02c | Putative holocytochrome-c1 synthase (EC 4.4.1.17) (Cytochrome c1 heme lyase) (CC1HL) |
Schizosaccharomyces pombe TI:4896 None |
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A0A2K3D4E1_CHLRE EnsemblPlants» |
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CHLRE_12g525776v5 | holocytochrome-c synthase (EC 4.4.1.17) |
Chlamydomonas reinhardtii TI:3055 None |
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A0A2K3D4E8_CHLRE EnsemblPlants» |
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CHLRE_12g525950v5 | holocytochrome-c synthase (EC 4.4.1.17) |
Chlamydomonas reinhardtii TI:3055 None |
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A0A2K3D4F1_CHLRE EnsemblPlants» |
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CHLRE_12g526030v5 | holocytochrome-c synthase (EC 4.4.1.17) |
Chlamydomonas reinhardtii TI:3055 None |
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A0A2K3D4F6_CHLRE EnsemblPlants» |
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CHLRE_12g526068v5 | holocytochrome-c synthase (EC 4.4.1.17) |
Chlamydomonas reinhardtii TI:3055 None |
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A0A2K3D4F8_CHLRE EnsemblPlants» |
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CHLRE_12g525750v5 | holocytochrome-c synthase (EC 4.4.1.17) |
Chlamydomonas reinhardtii TI:3055 None |
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A0A2K3D4G0_CHLRE EnsemblPlants» |
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CHLRE_12g526326v5 | holocytochrome-c synthase (EC 4.4.1.17) |
Chlamydomonas reinhardtii TI:3055 None |
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A0A2K3D4G1_CHLRE EnsemblPlants» |
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CHLRE_12g526150v5 | holocytochrome-c synthase (EC 4.4.1.17) |
Chlamydomonas reinhardtii TI:3055 None |
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A0A2K3D4G3_CHLRE EnsemblPlants» |
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CHLRE_12g526131v5 | holocytochrome-c synthase (EC 4.4.1.17) |
Chlamydomonas reinhardtii TI:3055 None |
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A0A2K3D4G5_CHLRE EnsemblPlants» |
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CHLRE_12g525970v5 | holocytochrome-c synthase (EC 4.4.1.17) |
Chlamydomonas reinhardtii TI:3055 None |
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A0A2K3D4H5_CHLRE EnsemblPlants» |
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CHLRE_12g526295v5 | holocytochrome-c synthase (EC 4.4.1.17) |
Chlamydomonas reinhardtii TI:3055 None |
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A0A2K3D4H8_CHLRE EnsemblPlants» |
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CHLRE_12g526515v5 | holocytochrome-c synthase (EC 4.4.1.17) |
Chlamydomonas reinhardtii TI:3055 None |
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A0A2K3D4I1_CHLRE EnsemblPlants» |
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CHLRE_12g526603v5 | holocytochrome-c synthase (EC 4.4.1.17) |
Chlamydomonas reinhardtii TI:3055 None |
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A0A2K3D4I5_CHLRE EnsemblPlants» |
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CHLRE_12g526200v5 | holocytochrome-c synthase (EC 4.4.1.17) |
Chlamydomonas reinhardtii TI:3055 None |
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A0A2K3D4J4_CHLRE EnsemblPlants» |
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CHLRE_12g526471v5 | holocytochrome-c synthase (EC 4.4.1.17) |
Chlamydomonas reinhardtii TI:3055 None |
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A0A2K3D4J7_CHLRE EnsemblPlants» |
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CHLRE_12g526559v5 | holocytochrome-c synthase (EC 4.4.1.17) |
Chlamydomonas reinhardtii TI:3055 None |
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A8J5I1_CHLRE EnsemblPlants» |
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CHLRE_12g526450v5 CHLRE_12g526650v5 | holocytochrome-c synthase (EC 4.4.1.17) |
Chlamydomonas reinhardtii TI:3055 None |
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