Collated Gene Ontology terms

Biological process: phospholipase A2 activity(2004, 2019, 2024) calcium ion binding(2024) hydrolase activity(2024) metal ion binding(2024) serine-type peptidase activity(2024) serine-type endopeptidase activity(2024) cysteine-type peptidase activity(2024) cysteine-type endopeptidase activity(2024) calcium-dependent phospholipase A2 activity(2003, 2021) identical protein binding(2024)
cysteine-type endopeptidase activity involved in execution phase of apoptosis2024 cysteine-type endopeptidase activity involved in apoptotic process2024

Molecular function: lipid catabolic process2004, 2024 phospholipid metabolic process2024 arachidonic acid secretion2024 triglyceride homeostasis2013, 2019, 2024 cholesterol homeostasis2013, 2019, 2024 proteolysis2024 low-density lipoprotein particle remodeling2020 regulation of programmed cell death2024 pyroptosis2024 protein autoprocessing2024
positive regulation of necroptotic process2024 positive regulation of apoptotic process2024 intrinsic apoptotic signaling pathway by p53 class mediator2024 hepatocyte apoptotic process2024 execution phase of apoptosis2024 epithelial cell differentiation2024 complement activation2024 cellular response to staurosporine2024 apoptotic process2024 activation of innate immune response2024

Cellular component: extracellular region2003, 2011, 2024 membrane2024 cytoplasm2024 nucleus2024 nucleoplasm2024 endoplasmic reticulum2011 cytosol2024 Golgi apparatus2011

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 0/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
Q18339_CAEEL
WormBase»
0.0
C31H1.5 CELE_C31H1.5 Phospholipase A(2) Caenorhabditis elegans
TI:6239 None
 
Q8MQ50_CAEEL
WormBase»
0.0
CELE_F44B9.10 F44B9.10 Secretory peptide Caenorhabditis elegans
TI:6239 None
 
A3KNJ5_DANRE
ZFIN»
0.5
zgc:162119 Group XIIA secretory phospholipase A2 precursor (EC
3.1.1.4) (Phospholipase A2, group XIIA) (Zgc:162119 protein)		 Danio rerio
TI:7955 None
 
F1R147_DANRE
ZFIN»
1.0
wu:fb26d02 Group XIIB secretory phospholipase A2-like protein
isoform X1 (Phospholipase A2, group XIIB)		 Danio rerio
TI:7955 None
 
Q9VUV6_DROME
FlyBase»
0.6
GXIVsPLA2 GXIVsPLA2, isoform A (GXIVsPLA2, isoform D
(EC 3.1.1.4)) (Group XIV secreted phospholipase A2)		 Drosophila melanogaster
TI:7227 None
 
A0A8V0XHP6_CHICK
Ensembl»
0.0
PLA2G12A Phospholipase A2 group XIIA Gallus gallus
TI:9031 None
   
A0A8V0ZJ65_CHICK
Ensembl»
0.0
PLA2G12B Phospholipase A2 group XIIB Gallus gallus
TI:9031 None
   
A0A2R8Y3M9_HUMAN
Ensembl»
0.0
Complement factor I Homo sapiens
TI:9606 None
 
PG12A_HUMAN
Ensembl»
1.1
PLA2G12A Group XIIA secretory phospholipase A2 (GXII
sPLA2) (sPLA2-XII) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase 12A)		 Homo sapiens
TI:9606 None
 
PG12B_HUMAN
Ensembl»
1.0
PLA2G12B Group XIIB secretory phospholipase A2-like protein (Group XIII
secretory phospholipase A2-like protein) (GXIII sPLA2-like) (sPLA2-GXIIB) (GXIIB)		 Homo sapiens
TI:9606 None
 
PG12A_MOUSE
Ensembl»
1.8
Pla2g12a Group XIIA secretory phospholipase A2 (GXII
sPLA2) (sPLA2-XII) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase 12A)		 Mus musculus
TI:10090 None
 
PG12B_MOUSE
AG»
2.4
Pla2g12b Group XIIB secretory phospholipase A2-like protein (Group XIII
secretory phospholipase A2-like protein) (GXIII sPLA2-like) (sPLA2-GXIIB) (GXIIB)		 Mus musculus
TI:10090 None
 
B0K018_RAT
RGD»
1.0
Pla2g12a Phospholipase A2, group XIIA (Pla2g12a protein) Rattus norvegicus
TI:10116 None
 
M0RCI5_RAT
RGD»
2.5
Pla2g12b Phospholipase A2, group XIIB Rattus norvegicus
TI:10116 None