Collated Gene Ontology terms

Biological process: phospholipase A2 activity(2003, 2004, 2019, 2025) calcium ion binding(2025) metal ion binding(2025) hydrolase activity(2025) serine-type peptidase activity(2025) peptidase activity(2025) serine-type endopeptidase activity(2025) cysteine-type peptidase activity(2025) cysteine-type endopeptidase activity(2025)

Molecular function: lipid catabolic process2004, 2025 phospholipid metabolic process2025 arachidonate secretion2025 triglyceride homeostasis2013, 2019, 2025 cholesterol homeostasis2013, 2019, 2025 lipid metabolic process2025 proteolysis2025 low-density lipoprotein particle remodeling2020 immune system process2025 protein processing2025
complement activation2025 apoptotic process2025

Cellular component: extracellular region2003, 2011, 2025 cytoplasm2025 membrane2025 endoplasmic reticulum2011 Golgi apparatus2011

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 0/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 2/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
Q9VUV6_DROME
FlyBase»
0.6
GXIVsPLA2 GXIVsPLA2, isoform A (GXIVsPLA2, isoform D
(EC 3.1.1.4)) (Group XIV secreted phospholipase A2)		 Drosophila melanogaster
TI:7227 None
 
A0A8V0XHP6_CHICK
Ensembl»
0.5
PLA2G12A Group XIIA secretory phospholipase
A2 (Phosphatidylcholine 2-acylhydrolase 12A)		 Gallus gallus
TI:9031 None
   
A3KNJ5_DANRE
ZFIN»
0.5
pla2g12a Group XIIA secretory phospholipase
A2 (Phosphatidylcholine 2-acylhydrolase 12A)		 Danio rerio
TI:7955 None
 
A0A2R8Y3M9_HUMAN
Ensembl»
0.0
Group XIIA secretory phospholipase A2
(EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase 12A)		 Homo sapiens
TI:9606 None
 
B0K018_RAT
RGD»
1.0
Pla2g12a Group XIIA secretory phospholipase A2
(EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase 12A)		 Rattus norvegicus
TI:10116 None
 
PG12A_HUMAN
Ensembl»
1.1
PLA2G12A Group XIIA secretory phospholipase A2 (GXII
sPLA2) (sPLA2-XII) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase 12A)		 Homo sapiens
TI:9606 None
 
PG12A_MOUSE
Ensembl»
2.3
Pla2g12a Group XIIA secretory phospholipase A2 (GXII
sPLA2) (sPLA2-XII) (EC 3.1.1.4) (Phosphatidylcholine 2-acylhydrolase 12A)		 Mus musculus
TI:10090 None
 
A0ACD6B6F5_DANRE
ZFIN»
0.0
pla2g12b Group XIIB secretory phospholipase
A2-like protein isoform X1		 Danio rerio
TI:7955 None 		     
A0A8V0ZJ65_CHICK
Ensembl»
1.0
PLA2G12B Group XIIB secretory phospholipase A2-like protein
(Group XIII secretory phospholipase A2-like protein) (sPLA2-GXIIB)		 Gallus gallus
TI:9031 None
   
M0RCI5_RAT
RGD»
2.5
Pla2g12b Group XIIB secretory phospholipase A2-like protein
(Group XIII secretory phospholipase A2-like protein) (sPLA2-GXIIB)		 Rattus norvegicus
TI:10116 None
   
PG12B_HUMAN
Ensembl»
1.0
PLA2G12B Group XIIB secretory phospholipase A2-like protein (Group XIII
secretory phospholipase A2-like protein) (GXIII sPLA2-like) (sPLA2-GXIIB) (GXIIB)		 Homo sapiens
TI:9606 None
 
PG12B_MOUSE
AG»
3.4
Pla2g12b Group XIIB secretory phospholipase A2-like protein (Group XIII
secretory phospholipase A2-like protein) (GXIII sPLA2-like) (sPLA2-GXIIB) (GXIIB)		 Mus musculus
TI:10090 None