Collated Gene Ontology terms

Biological process: RNA binding(2013, 2014, 2020, 2025) protein-macromolecule adaptor activity(2013) ubiquitin protein ligase activity(2021) myosin binding(2013) enzyme regulator activity(2011) DNA binding(2025)

Molecular function: mRNA processing2023, 2025 mRNA 3'-end processing by stem-loop binding and cleavage2009, 2025 mRNA 3'-end processing2025 pericentric heterochromatin formation2024, 2025 nuclear mRNA surveillance of mRNA 3'-end processing2020, 2025 co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway2020, 2025 ubiquitin-dependent protein catabolic process2021 termination of RNA polymerase II transcription, poly(A)-coupled2025 response to xenobiotic stimulus2014 regulation of mRNA 3'-end processing2011
positive regulation of transcription by RNA polymerase II2018

Cellular component: mRNA cleavage and polyadenylation specificity factor complex2004, 2006, 2011, 2013, 2017, 2025 nucleus2009, 2011, 2022, 2025 nucleoplasm2015, 2024, 2025 nuclear exosome focus2020, 2025 heterochromatin island2024, 2025 chromatin2020, 2025 cytosol2023

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 2/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 15/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 1/4 
Harosa: 3/4 
Hacrobia: 0/0 
Plants: 1/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
FIP1_HUMAN
Ensembl»
1.8
FIP1L1 Pre-mRNA 3'-end-processing factor FIP1 (hFip1) (FIP1-like 1
protein) (Factor interacting with PAP) (Rearranged in hypereosinophilia)		 Homo sapiens
TI:9606 None
 
FIP1_MOUSE
Ensembl»
3.0
Fip1l1 Pre-mRNA 3'-end-processing factor
FIP1 (FIP1-like 1 protein)		 Mus musculus
TI:10090 None
 
FIP1_YEAST
SGD»
4.6
FIP1 Pre-mRNA polyadenylation factor FIP1 Saccharomyces cerevisiae
TI:4932 None
 
A0A164D3G3_CAEEL
WormBase»
0.5
fipp-1 Pre-mRNA polyadenylation factor
Fip1 domain-containing protein		 Caenorhabditis elegans
TI:6239 None
 
FIP1X_SCHPO
PomBase»
2.4
SPAC22G7.10 Pre-mRNA polyadenylation factor fip1 Schizosaccharomyces pombe
TI:4896 None
 
FIP1_DANRE
ZFIN»
0.5
fip1l1 Pre-mRNA 3'-end-processing factor
FIP1 (FIP1-like 1 protein)		 Danio rerio
TI:7955 None
 
FIP1_RAT
RGD»
1.0
Fip1l1 Pre-mRNA 3'-end-processing factor
FIP1 (FIP1-like 1 protein)		 Rattus norvegicus
TI:10116 None
 
Q54IF1_DICDI
dictyBase»
0.5
fip1l1 Cleavage and polyadenylation
specificity factor FIP1		 Dictyostelium discoideum
TI:44689 None
 
Q54RC2_DICDI
dictyBase»
0.0
DDB_G0283325 Uncharacterized protein Dictyostelium discoideum
TI:44689 None
 
Q9VN31_DROME
FlyBase»
2.9
Fip1 Factor interacting with poly(A) polymerase 1 Drosophila melanogaster
TI:7227 None
 
A0A8V0YCT7_CHICK
Ensembl»
0.5
FIP1L1L Pre-mRNA polyadenylation factor
Fip1 domain-containing protein		 Gallus gallus
TI:9031 None
   
A0A8V0YQ64_CHICK
Ensembl»
0.5
FIP1L1 Pre-mRNA 3'-end-processing factor
FIP1 (FIP1-like 1 protein)		 Gallus gallus
TI:9031 None