Collated Gene Ontology terms

Biological process: cobalamin binding(2007, 2009, 2011, 2017, 2020, 2022, 2024) cargo receptor ligand activity(2021, 2022, 2023, 2024) metal ion binding(2024) vitamin binding(2005) molecular sequestering activity(2022) catalytic activity(2024)

Molecular function: cobalamin transport2005, 2009, 2017, 2021, 2022, 2023, 2024 cobalt ion transport2024 cellular response to xenobiotic stimulus2008

Cellular component: extracellular space2003, 2007, 2009, 2014, 2017, 2018, 2021, 2022, 2024 extracellular region2013, 2021, 2024 microvillus2009, 2024 endosome2009, 2024 apical plasma membrane2009, 2024 external side of plasma membrane2021, 2024 membrane2024 lysosomal lumen2021 tertiary granule lumen2016 specific granule lumen2016
plasma membrane2021

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 0/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 1/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
TCO2_HUMAN
Ensembl»
4.3
TCN2 Transcobalamin-2 (TC-2) (Transcobalamin
II) (TC II) (TCII)		 Homo sapiens
TI:9606 None
 
IF_HUMAN
Ensembl»
4.3
CBLIF Cobalamin binding intrinsic factor (Gastric
intrinsic factor) (Intrinsic factor) (IF) (INF)		 Homo sapiens
TI:9606 None
 
TCO2_RAT
RGD»
4.7
Tcn2 Transcobalamin-2 (TC-2) (Transcobalamin
II) (TC II) (TCII)		 Rattus norvegicus
TI:10116 None
 
IF_RAT
RGD»
4.2
Cblif Cobalamin binding intrinsic factor (Gastric
intrinsic factor) (Intrinsic factor) (IF) (INF)		 Rattus norvegicus
TI:10116 None
 
TCO2_MOUSE
Ensembl»
3.4
Tcn2 Transcobalamin-2 (TC-2) (Transcobalamin
II) (TC II) (TCII)		 Mus musculus
TI:10090 None
 
IF_MOUSE
Ensembl»
3.4
Cblif Cobalamin binding intrinsic factor (Gastric
intrinsic factor) (Intrinsic factor) (IF) (INF)		 Mus musculus
TI:10090 None
 
TCO1_HUMAN
Ensembl»
3.5
TCN1 Transcobalamin-1 (TC-1) (Haptocorrin) (HC) (Protein
R) (Transcobalamin I) (TC I) (TCI)		 Homo sapiens
TI:9606 None
 
F2Z4S3_DANRE
ZFIN»
2.6
si:ch211-102c2.6 Transcobalamin II (Transcobalamin-2 precursor) Danio rerio
TI:7955 None
 
Y3556_DROME
FlyBase»
1.0
CG3556 Uncharacterized protein CG3556 Drosophila melanogaster
TI:7227 None
 
A0A8V0X783_CHICK
Ensembl»
0.0
TCN2 Transcobalamin 2 Gallus gallus
TI:9031 None
   
A0A8V1A3I6_CHICK
Ensembl»
0.0
GIF DUF4430 domain-containing protein Gallus gallus
TI:9031 None
   
A2BFS9_DANRE
ZFIN»
1.6
hm:zeh0098 Transcobalamin beta
b (Transcobalamin-like precursor)		 Danio rerio
TI:7955 None
 
A2BFT0_DANRE
ZFIN»
0.8
LOC566714 Similar to Transcobalamin-1 (Transcobalamin I) (TCI) (TC
I) (Transcobalamin beta a) (Transcobalamin beta a precursor)		 Danio rerio
TI:7955 None