Collated Gene Ontology terms

Biological process: actin binding(2025) transcription coregulator activity(2005, 2010, 2011)

Molecular function: DNA-templated transcription2025 stem cell population maintenance2012 regulation of transcription by RNA polymerase II2005, 2007 positive regulation of transcription initiation by RNA polymerase II2024, 2025 positive regulation of transcription elongation by RNA polymerase II2024, 2025 negative regulation of smooth muscle cell differentiation2012 RNA polymerase II preinitiation complex assembly2024, 2025 transcription by RNA polymerase II2011 positive regulation of DNA-templated transcription2024

Cellular component: nucleus2011, 2024, 2025 mediator complex2007, 2009, 2012, 2025 nucleoplasm2015, 2024, 2025 cytoskeleton2012, 2025 cortical actin cytoskeleton2012, 2025 membrane2025 cytoplasm2025 core mediator complex2025

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 1/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Show all] GO terms Seq. links Protein domain links
MED28_DANRE
ZFIN»
0.0
med28 Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Danio rerio
TI:7955 None
 
MED28_DICDI
dictyBase»
2.0
med28 Putative mediator of RNA polymerase II transcription
subunit 28 (Putative mediator complex subunit 28)		 Dictyostelium discoideum
TI:44689 None
 
MED28_DROME
FlyBase»
3.7
MED28 Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28) (dMED23)		 Drosophila melanogaster
TI:7227 None
 
A0A8V0Y948_CHICK
Ensembl»
0.0
MED28 Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Gallus gallus
TI:9031 None
   
MED28_HUMAN
Ensembl»
1.8
MED28 Mediator of RNA polymerase II transcription subunit 28 (Endothelial-derived protein 1) (Mediator
complex subunit 28) (Merlin and Grb2-interacting cytoskeletal protein) (Magicin) (Tumor angiogenesis marker EG-1)		 Homo sapiens
TI:9606 None
 
MED28_MOUSE
Ensembl»
3.4
Med28 Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Mus musculus
TI:10090 None
 
MED28_RAT
RGD»
1.0
Med28 Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Rattus norvegicus
TI:10116 None