Collated Gene Ontology terms

Biological process: actin binding(2024) transcription coregulator activity(2005, 2010, 2011)

Molecular function: somatic stem cell population maintenance2012, 2024 negative regulation of smooth muscle cell differentiation2012, 2024 regulation of transcription by RNA polymerase II2005, 2007 positive regulation of transcription initiation by RNA polymerase II2014, 2018 positive regulation of transcription elongation by RNA polymerase II2014, 2018 RNA polymerase II preinitiation complex assembly2014, 2018 transcription by RNA polymerase II2011

Cellular component: nucleus2011, 2014, 2018, 2024 mediator complex2007, 2009, 2012, 2022, 2024 core mediator complex2014, 2018, 2024 nucleoplasm2015, 2023, 2024 cytoskeleton2012, 2024 cortical actin cytoskeleton2012, 2024 membrane2024 cytoplasm2024

Phylogenetic distribution

Chordates: 22/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 1/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 0/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 0/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 2/3 
Excavates: 0/4 
Harosa: 0/4 
Hacrobia: 0/0 
Plants: 1/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 0 2 4 6 8 10 Knownness

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Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
A0A2K3DJ05_CHLRE
EnsemblPlants»
0.0
CHLRE_07g320300v5 Mediator of RNA polymerase
II transcription subunit 28		 Chlamydomonas reinhardtii
TI:3055 None
 
A0A310U7F8_XENLA
Xenbase»
0.0
med28.L Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Xenopus laevis
TI:8355 None
   
A0A6I8NX83_ORNAN
Ensembl»
0.0
MED28 Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Ornithorhynchus anatinus
TI:9258 None
   
A0A7M7NTN1_STRPU
EnsemblMetazoa»
0.0
Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Strongylocentrotus purpuratus
TI:7668 None
   
A0A803SXE5_ANOCA
Ensembl»
0.0
Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Anolis carolinensis
TI:28377 None
   
A0A8D1SI70_PIG
Ensembl»
0.0
MED28 Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Sus scrofa
TI:9823 None
   
A0A8I3MAU1_CANLF
Ensembl»
0.0
MED28 Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Canis lupus
TI:9612 None
   
A0A8V0Y948_CHICK
Ensembl»
0.0
MED28 Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Gallus gallus
TI:9031 None
   
A0A9J7LDG3_BRAFL
CTD»
0.0
LOC118417913 Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Branchiostoma floridae
TI:7739 None
   
A7S0P6_NEMVE
EnsemblMetazoa»
0.0
NEMVEDRAFT_v1g204982 Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Nematostella vectensis
TI:45351 None
 
B7PAW5_IXOSC
EnsemblMetazoa»
0.0
8027162 Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Ixodes scapularis
TI:6945 None
 
D6WAK9_TRICA
EnsemblMetazoa»
0.0
AUGUSTUS-3.0.2_01173 Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Tribolium castaneum
TI:7070 None
 
E9HJR9_DAPPU
EnsemblMetazoa»
0.0
DAPPUDRAFT_114938 Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Daphnia pulex
TI:6669 None
 
F1A4B2_DICPU
EnsemblProtists»
0.0
DICPUDRAFT_11971 Mediator complex subunit 28 Dictyostelium purpureum
TI:5786 None
 
F1MNZ6_BOVIN
Ensembl»
0.0
MED28 Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Bos taurus
TI:9913 None
   
F6PSC7_HORSE
Ensembl»
0.0
MED28 Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Equus caballus
TI:9796 None
   
F6S9Q4_MONDO
Ensembl»
0.0
MED28 Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Monodelphis domestica
TI:13616 None
   
G1KKU8_ANOCA
Ensembl»
0.0
MED28 Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Anolis carolinensis
TI:28377 None
   
G3QFM0_GORGO
Ensembl»
0.0
MED28 Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Gorilla gorilla
TI:9593 None
 
G7MSM6_MACMU
Ensembl»
0.0
MED28 Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Macaca mulatta
TI:9544 None
   
H2LV36_ORYLA
Ensembl»
0.0
med28 Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Oryzias latipes
TI:8090 None
   
H2XQC0_CIOIN
Ensembl»
0.0
LOC100186879 Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Ciona intestinalis
TI:7719 None
 
K7BCC3_PANTR
Ensembl»
0.0
MED28 Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Pan troglodytes
TI:9598 None
 
M3WXV8_FELCA
Ensembl»
0.0
MED28 Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Felis catus
TI:9685 None
 
MED28_BOVIN
CTD»
0.0
MED28 Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Bos taurus
TI:9913 None
 
MED28_DANRE
ZFIN»
0.0
med28 Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Danio rerio
TI:7955 None
 
MED28_DICDI
dictyBase»
2.0
med28 Putative mediator of RNA polymerase II transcription
subunit 28 (Putative mediator complex subunit 28)		 Dictyostelium discoideum
TI:44689 None
 
MED28_DROME
FlyBase»
3.1
MED28 Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28) (dMED23)		 Drosophila melanogaster
TI:7227 None
 
MED28_HUMAN
Ensembl»
1.8
MED28 Mediator of RNA polymerase II transcription subunit 28 (Endothelial-derived protein 1) (Mediator
complex subunit 28) (Merlin and Grb2-interacting cytoskeletal protein) (Magicin) (Tumor angiogenesis marker EG-1)		 Homo sapiens
TI:9606 None
 
MED28_MOUSE
Ensembl»
3.4
Med28 Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Mus musculus
TI:10090 None
 
MED28_RAT
RGD»
1.0
Med28 Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Rattus norvegicus
TI:10116 None
 
MED28_XENTR
Xenbase»
0.0
med28 Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Xenopus tropicalis
TI:8364 None
 
Q7PS84_ANOGA
EnsemblMetazoa»
0.0
1271602 Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Anopheles gambiae
TI:7165 None
 
T1FAU8_HELRO
EnsemblMetazoa»
0.0
20205947 Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Helobdella robusta
TI:6412 None
 
W5M624_LEPOC
Ensembl»
0.0
Mediator of RNA polymerase II transcription
subunit 28 (Mediator complex subunit 28)		 Lepisosteus oculatus
TI:7918 None