Collated Gene Ontology terms

Biological process: transferase activity(2025) methyltransferase activity(2025) rRNA (adenine) methyltransferase activity(2013, 2021, 2025) S-adenosyl-L-methionine binding(2017, 2023, 2025) protein-containing complex binding(2024, 2025) S-adenosylmethionine-dependent methyltransferase activity(2013)

Molecular function: methylation2025 regulation of TORC1 signaling2023, 2025 rRNA methylation2014, 2025 cellular response to amino acid starvation2017, 2025 positive regulation of TORC1 signaling2023, 2025 cellular response to methionine2023, 2025 negative regulation of TORC1 signaling2025 ribosomal large subunit biogenesis2025 protein-containing complex localization2025 protein localization to lysosome2025
positive regulation of translational initiation2025 negative regulation of translational initiation2025 cytoplasmic translation2025 cellular response to nutrient levels2025 TORC1 signaling2025

Cellular component: nucleolus2009, 2013, 2018, 2021, 2025 nucleus2009, 2025 cytosol2019 cytoplasm2025

Phylogenetic distribution

Chordates: 21/21 
Echinoderms: 0/0 
Hemichordates: 1/1 
Annelids: 0/1 
Molluscs: 0/0 
Bryozoans: 0/0 
Platyhelminthes: 0/0 
Rotifers: 0/0 
Nematodes: 0/3 
Arthropods: 5/5 
Tardigrades: 0/0 
Placozoa: 1/1 
Cnidaria: 1/1 
Porifera: 0/0 
Choanoflagellates+: 15/1 
Dikarya: 0/14 
Fungi (other): 0/1 
Protozoa: 0/3 
Excavates: 2/4 
Harosa: 1/4 
Hacrobia: 0/0 
Plants: 0/39 
Archea: 0/8 
Bacteria: 0/35 

Find a cluster

Protein ID:
UniProt ID, accession, gene name or model org. database name
Cluster ID:
e.g. "UKP00123" or "123"

Download

Protein sequences (FASTA format)

Knownness history

2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 2025 0 2 4 6 8 10 Knownness

Click here to switch to the previous version of the database.

Proteins

UniProt ID
Organism DB»		 Standard knownness clustom knownness Gene name Description Species  [Key only] GO terms Seq. links Protein domain links
A0A1L8GYV9_XENLA
Xenbase»
0.0
samtor.L S-adenosylmethionine sensor upstream of mTORC1
(Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)		 Xenopus laevis
TI:8355 None
   
A0A1S4H0J8_ANOGA
EnsemblMetazoa»
0.0
S-adenosylmethionine sensor upstream of mTORC1
(Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)		 Anopheles gambiae
TI:7165 None
 
A0A287B754_PIG
Ensembl»
0.0
BMT2 S-adenosylmethionine sensor upstream of mTORC1
(Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)		 Sus scrofa
TI:9823 None
 
A0A3B3HUC4_ORYLA
Ensembl»
0.0
SAMTOR S-adenosylmethionine sensor upstream of mTORC1
(Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)		 Oryzias latipes
TI:8090 None
   
A0A5F8GI30_MONDO
Ensembl»
0.0
BMT2 S-adenosylmethionine sensor upstream of mTORC1
(Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)		 Monodelphis domestica
TI:13616 None
   
A0A7M7PF12_STRPU
EnsemblMetazoa»
0.0
S-adenosylmethionine sensor upstream of mTORC1
(Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)		 Strongylocentrotus purpuratus
TI:7668 None
   
A0A7M7RB75_STRPU
EnsemblMetazoa»
0.0
S-adenosylmethionine sensor upstream of mTORC1
(Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)		 Strongylocentrotus purpuratus
TI:7668 None
   
A0A7U2F8F0_PHANO
TubercuList»
0.0
JI435_090110 25S rRNA adenine-N(1)
methyltransferase (EC 2.1.1.-)		 Phaeosphaeria nodorum
TI:13684 None
 
A0A8I3SCN3_CANLF
Ensembl»
0.0
BMT2 S-adenosylmethionine sensor upstream of mTORC1
(Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)		 Canis lupus
TI:9612 None
   
A0A9J7L4H9_BRAFL
euHCVdb»
0.0
LOC118415350 S-adenosylmethionine sensor upstream of mTORC1
(Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)		 Branchiostoma floridae
TI:7739 None
   
A0A9J7LMN0_BRAFL
euHCVdb»
0.0
LOC118422339 S-adenosylmethionine sensor upstream of mTORC1
(Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)		 Branchiostoma floridae
TI:7739 None
   
A0ABI7WFJ7_FELCA
Ensembl»
0.0
BMT2 S-adenosylmethionine sensor upstream of mTORC1
(Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)		 Felis catus
TI:9685 None
   
A7E400_SCLS1
TubercuList»
0.0
SS1G_00022 25S rRNA adenine-N(1)
methyltransferase (EC 2.1.1.-)		 Sclerotinia sclerotiorum
TI:5180 None
 
A7RVZ9_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g95431 S-adenosylmethionine sensor upstream of mTORC1
(Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)		 Nematostella vectensis
TI:45351 None
 
A7SA21_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g243875 S-adenosylmethionine sensor upstream of mTORC1
(Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)		 Nematostella vectensis
TI:45351 None
 
A7SFM2_NEMVE
euHCVdb»
0.0
NEMVEDRAFT_v1g116530 Uncharacterized protein Nematostella vectensis
TI:45351 None
 
A9UQ29_MONBE
neXtProt»
0.0
MONBRDRAFT_22269 Uncharacterized protein Monosiga brevicollis
TI:81824 None
 
A9VCB4_MONBE
euHCVdb»
0.0
MONBRDRAFT_12452 Probable methyltransferase BMT2
homolog (EC 2.1.1.-)		 Monosiga brevicollis
TI:81824 None
 
B3RUW6_TRIAD
CTD»
0.0
TRIADDRAFT_55439 S-adenosylmethionine sensor upstream of mTORC1
(Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)		 Trichoplax adhaerens
TI:10228 None
 
B3RWS7_TRIAD
CTD»
0.0
TRIADDRAFT_56862 Uncharacterized protein Trichoplax adhaerens
TI:10228 None
 
B6K335_SCHJY
TubercuList»
0.0
bmt2 25S rRNA adenine-N(1)
methyltransferase (EC 2.1.1.-)		 Schizosaccharomyces japonicus
TI:4897 None
 
B7QMD5_IXOSC
EnsemblMetazoa»
0.0
IscW_ISCW023505 Uncharacterized protein Ixodes scapularis
TI:6945 None
 
BMT2_SCHPO
PomBase»
1.5
SPAC630.10 25S rRNA adenine-N(1)
methyltransferase (EC 2.1.1.-)		 Schizosaccharomyces pombe
TI:4896 None
 
BMT2_YEAST
SGD»
2.6
BMT2 25S rRNA (adenine(2142)-N(1))-methyltransferase (EC 2.1.1.286)
(Base MethylTransferase of 25S RNA)		 Saccharomyces cerevisiae
TI:4932 None
 
D3ZV22_RAT
RGD»
3.0
Samtor S-adenosylmethionine sensor upstream of mTORC1
(Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)		 Rattus norvegicus
TI:10116 None
   
D6WEG1_TRICA
euHCVdb»
0.0
GLEAN_03256 S-adenosylmethionine sensor upstream of mTORC1
(Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)		 Tribolium castaneum
TI:7070 None
 
E1B7X8_BOVIN
Ensembl»
0.0
BMT2 S-adenosylmethionine sensor upstream of mTORC1
(Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)		 Bos taurus
TI:9913 None
   
E3KY48_PUCGT
TubercuList»
0.0
PGTG_15090 25S rRNA adenine-N(1)
methyltransferase (EC 2.1.1.-)		 Puccinia graminis
TI:5297 None
 
E9HEG8_DAPPU
euHCVdb»
0.0
EOG090X0FUY S-adenosylmethionine sensor upstream of mTORC1
(Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)		 Daphnia pulex
TI:6669 None
 
F4NVV7_BATDJ
euHCVdb»
0.0
BATDEDRAFT_86179 25S rRNA adenine-N(1)
methyltransferase (EC 2.1.1.-)		 Batrachochytrium dendrobatidis
TI:109871 None
 
F6Z4Z8_HORSE
Ensembl»
0.0
BMT2 S-adenosylmethionine sensor upstream of mTORC1
(Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)		 Equus caballus
TI:9796 None
   
G1KG09_ANOCA
Ensembl»
0.0
BMT2 S-adenosylmethionine sensor upstream of mTORC1
(Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)		 Anolis carolinensis
TI:28377 None
   
G3S2J7_GORGO
Ensembl»
0.0
BMT2 S-adenosylmethionine sensor upstream of mTORC1
(Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)		 Gorilla gorilla
TI:9593 None
 
G7MM54_MACMU
Ensembl»
0.0
BMT2 S-adenosylmethionine sensor upstream of mTORC1
(Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)		 Macaca mulatta
TI:9544 None
 
H2XS31_CIOIN
Ensembl»
0.0
LOC100185310 S-adenosylmethionine sensor upstream of mTORC1
(Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)		 Ciona intestinalis
TI:7719 None
 
H2XZZ2_CIOIN
Ensembl»
0.0
S-adenosylmethionine sensor upstream of mTORC1
(Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)		 Ciona intestinalis
TI:7719 None
 
H3GRM7_PHYRM
EnsemblProtists»
0.0
Probable methyltransferase BMT2
homolog (EC 2.1.1.-)		 Phytophthora ramorum
TI:164328 None
 
K7CX06_PANTR
Ensembl»
0.0
BMT2 S-adenosylmethionine sensor upstream of mTORC1
(Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)		 Pan troglodytes
TI:9598 None
 
Q4QB47_LEIMA
TubercuList»
0.0
LMJF_23_1090 Probable methyltransferase BMT2
homolog (EC 2.1.1.-)		 Leishmania major
TI:5664 None
 
Q4WTP8_ASPFU
TubercuList»
0.0
AFUA_5G05660 25S rRNA adenine-N(1)
methyltransferase (EC 2.1.1.-)		 Aspergillus fumigatus
TI:746128 None
 
Q52KX5_XENLA
Xenbase»
0.0
samtor.S S-adenosylmethionine sensor upstream of mTORC1
(Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)		 Xenopus laevis
TI:8355 None
 
Q57W77_TRYB2
TubercuList»
0.0
Tb08.28F14.350 Probable methyltransferase BMT2
homolog (EC 2.1.1.-)		 Trypanosoma brucei
TI:5691 None
 
Q59ZI0_CANAL
CGD»
0.0
BMT2 25S rRNA adenine-N(1)
methyltransferase (EC 2.1.1.-)		 Candida albicans
TI:5476 None
 
Q5AS75_EMENI
TubercuList»
0.0
ANIA_08855 25S rRNA adenine-N(1)
methyltransferase (EC 2.1.1.-)		 Emericella nidulans
TI:162425 None
 
Q5KF47_CRYD1
TubercuList»
0.0
CNF03010 25S rRNA adenine-N(1)
methyltransferase (EC 2.1.1.-)		 Cryptococcus deneoformans
TI:40410 None
 
Q6BZX8_YARLI
TubercuList»
0.0
BMT2 25S rRNA adenine-N(1)
methyltransferase (EC 2.1.1.-)		 Yarrowia lipolytica
TI:4952 None
 
Q757I7_EREGS
euHCVdb»
0.0
BMT2 25S rRNA adenine-N(1)
methyltransferase (EC 2.1.1.-)		 Eremothecium gossypii
TI:33169 None
 
Q7SBS8_NEUCR
TubercuList»
0.0
NCU06227 25S rRNA adenine-N(1)
methyltransferase (EC 2.1.1.-)		 Neurospora crassa
TI:5141 None
 
SAMTR_CHICK
Ensembl»
1.5
SAMTOR S-adenosylmethionine sensor upstream of mTORC1
(Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)		 Gallus gallus
TI:9031 None
 
SAMTR_DANRE
ZFIN»
1.5
samtor S-adenosylmethionine sensor upstream of mTORC1
(Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)		 Danio rerio
TI:7955 None
 
SAMTR_DROME
FlyBase»
0.8
CG3570 Probable S-adenosyl-L-methionine-dependent methyltransferase (EC 2.1.1.-)
(S-adenosylmethionine sensor upstream of mTORC1) (dSamtor)		 Drosophila melanogaster
TI:7227 None
 
SAMTR_HUMAN
Ensembl»
4.8
SAMTOR S-adenosylmethionine sensor upstream of mTORC1
(Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)		 Homo sapiens
TI:9606 None
 
SAMTR_MOUSE
Ensembl»
8.5
Samtor S-adenosylmethionine sensor upstream of mTORC1
(Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)		 Mus musculus
TI:10090 None
 
SAMTR_XENLA
Xenbase»
0.0
samtor S-adenosylmethionine sensor upstream of mTORC1
(Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)		 Xenopus laevis
TI:8355 None
 
SAMTR_XENTR
Xenbase»
0.0
samtor S-adenosylmethionine sensor upstream of mTORC1
(Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)		 Xenopus tropicalis
TI:8364 None
 
W5NG58_LEPOC
Ensembl»
0.0
BMT2 S-adenosylmethionine sensor upstream of mTORC1
(Probable methyltransferase BMT2 homolog) (EC 2.1.1.-)		 Lepisosteus oculatus
TI:7918 None